Clinical trials: Frailty/Sarcopenia
Sarcopenia, Frailty
Health Data from Well on My Legs Program
The percentage of people aged over 80 will double in 25 years, reaching 10% of the population. This means that care practices for older adults will have to be adapted.
- Conditions
- Sarcopenia, Frailty, Physical Inactivity, Fear
- Trial name
- DS-BSSJ (NCT06659484)
- Testing
- Assessment, Multicomponent exercise program, Follow-up at T3 + 6 months and T3 + 12 months
- Where
- France
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Frailty, Sarcopenia
FrAilty Care and wEll-funcTion in Community Dwelling Older Adults
This study is looking at whether older people could benefit from an online monitoring platform to support their individual ambitions to maintain or improve functional ability.
- Conditions
- Frailty, Sarcopenia, Aging
- Trial name
- FACET (NCT03707145)
- Testing
- Consultation, Online Support, Empowered
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Aberystwyth University
Frailty, Surgery
Retrospective Analysis of Sarcopenia in Older Patients Undergoing Laparotomy
Assess the influence of sarcopenia on outcomes of emergency laparotomy in the over 65 age group
- Conditions
- Frailty, Surgery, Emergencies
- Trial name
- NCT04493710
- Testing
- Sarcopenia estimation
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Wirral University Teaching Hospital NHS Trust
Metabolic Disease
Effectiveness of Technology for Metabolic Diseases Combined Sarcopenia
The lifestyle program intervention program focusing on healthy dietary habit and exercise effectively prevents metabolic syndrome, sarcopenia or frailty.
- Trial name
- NCT05476536
- Testing
- self-management skills and healthy technology APP
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Chang Gung University of Science and Technology
Sarcopenia, Muscle Loss
Effect of Strength Training and Protein Ingestion in Old Versus Very-old
From 3 interventiongroups in the project with ClinicalTrials.gov ID NCT02034760, namely: HRTW: Heavy Strength Training x3/week \& 20g whey protein twice daily.
- Trial name
- NCT02105922
- Testing
- Heavy Resistance Training, Light Intensity Training, Protein Whey
- Where
- Denmark
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Healthy Aging, Sarcopenia
Plant-based Diets and Healthy Aging
This prospective study investigates the health effects of vegetarian and plant-based diets in middle-aged and older adults in Taiwan, specifically, recruiting 5000 Tzu Chi volunteers.
- Conditions
- Healthy Aging, Sarcopenia, Frailty, Cognitive Decline
- Trial name
- TCAS (NCT07151365)
- Where
- Taiwan
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- National Health Research Institutes, Taiwan
Sarcopenia
Frailty and Assocciated Factors in Sarcopenia
Primary sarcopenia is a condition that occurs with the aging process and is characterized by symptoms such as decreased muscle mass, impaired muscle function and decreased physical strength.
- Trial name
- NCT06931964
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Sarcopenia, Muscle Loss
Counteracting Age-related Loss of Skeletal Muscle Mass (CALM)
Up to 66 healthy elderly individuals (at least 65 years old) are recruited as subjects. They will be recruited as a subgroup to protocol ID: H-4-2013-070.
- Trial name
- CALM (NCT02115698)
- Testing
- Heavy Resistance Training, Light Intensity Training, Protein Whey
- Where
- Denmark
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Oral Frailty, Depression
Group Reading and Oral Exercise Program for Older Adults
Depression is common among older adults and is often associated with declines in physical and oral health. Non-pharmacological, community-based interventions are needed to support both mental and physical well-being.
- Conditions
- Oral Frailty, Depression, Sarcopenia, Physical Function Decline
- Trial name
- NCT07550335
- Testing
- Reading and Oral Exercise Program
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
Sarcopenia, Old Age; Debility
Study of the Validity and Reliability of Two Digital Dynamometers in Older People
It is a cross-sectional, randomized, and single-center study with a duration of 6 months. The study will follow the STROBE guidelines for cross-sectional studies and CONSORT 2024.
- Conditions
- Sarcopenia, Old Age; Debility, Frailty
- Trial name
- SOVARDDIOP (NCT06623019)
- Testing
- Validation and reliability
- Where
- Spain
- Volunteers
- 413 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Ambulatory Geriatric Outpatients at High Risk of Frailty
Impact of Chronic Disease Control and Aging Psychology on Outcomes of Frailty-Sarcopenia Syndrome in Ambulatory Geriatric Patients
Pursuant to our previous longitudinal study (ClinicalTrials.gov ID: NCT02073370) in geriatric outpatients cooperated with the Department of Family Medicine, Department of Geriatrics and Gerontology, National Taiwan University…
- Trial name
- NCT02160093
- Where
- Taiwan
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Sarcopenia, Frailty
Prevalence of Two Major Geriatric Syndromes: Sarcopenia and Frailty
Sarcopenia and frailty are two major syndromes in older adults. They are shown to be associated with low levels of functioning and higher rates of morbidity and mortality.
- Conditions
- Sarcopenia, Frailty, Frailty Syndrome
- Trial name
- NCT04146844
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Goztepe Training and Research Hospital
Sarcopenia
Multicomponent Intervention for Physical Frailty and Sarcopenia
The SPRINTT study will evaluate the efficacy of a multicomponent intervention programme (physical activity, nutritional counselling/dietary intervention, and information and communications technology intervention) compared with a…
- Trial name
- SPRINTT (NCT02582138)
- Testing
- Multicomponent intervention (MCI), Healthy Aging Lifestyle Education (HALE)
- Where
- Italy
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Sarcopenia
A Study of Muscle Strength Maintenance in Older Adults
This research study is being done to see whether losartan can prevent the decrease in strength associated with aging. Muscle loss is associated with aging and has multiple symptoms such as weakness, slowness, and fatigue…
- Trial name
- NCT01989793
- Testing
- Losartan
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Mobility
Best Function of Range of Motion (cRCT)
Mobility is a crucial factor for independence and quality of life in older people. However, the majority of those in retirement homes are not physically active to maintain mobility and independence.
- Trial name
- bestform (NCT04207307)
- Testing
- Multimodal exercise program, Usual Care
- Where
- Germany
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Sarcopenia, Aging
Effects of Polyphenol Supplementation and Exercise on Physical Performance in Older Adults
After approximately age 40 years, individuals experience a natural loss of muscle mass, strength, and physical function that is linked to higher risks of falls, disability, loss of independence, and mortality.
- Conditions
- Sarcopenia, Aging, Frailty
- Trial name
- NCT07441343
- Testing
- Polyphenol Rich-Extract, Resistance Band-Based & Aerobic Stationary Cycling Exercise
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Dr. Chris McGlory, PhD
Cognitive Decline, Sarcopenia
Holistic Integration for Healthy Longevity and Aging in Place
Background: Taiwan is experiencing rapid population aging, with a growing prevalence of chronic diseases and functional impairments among older adults.
- Conditions
- Cognitive Decline, Sarcopenia, Depression Disorders, Nutrition Disorder
- Trial name
- HIHOPE (NCT06882434)
- Testing
- Local intervention program, Referral Process, Telehealth Education & Digital Integration
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Frailty, Sarcopenia
Development of Frailty Prevention Clinic in Geriatric Comprehensive Clinic RSCM:
There is an increasing number of elderly population, not only in Indonesia, but also in the world. With increasing of age, there is also an increasing number of elderly with sarcopenia and frailty.
- Conditions
- Frailty, Sarcopenia, Resistance Training
- Trial name
- NCT05511311
- Testing
- Resistance Training, Standard Therapy
- Where
- Indonesia
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Sarcopenia, Nicotinamide Adenine Dinucleotide Concentration
Impacts of Nicotinamide Riboside on Functional Capacity and Muscle Physiology in Older Veterans
Frailty is an age-associated clinical condition of poor physiological reserve that increases risks for falls, hospitalization and mortality.
- Conditions
- Sarcopenia, Nicotinamide Adenine Dinucleotide Concentration, Muscle Quality and NAD+ Content
- Trial name
- NR-VET (NCT04691986)
- Testing
- Nicotinamide Riboside
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Frailty, Sarcopenia
A Randomized Control Trial of an Intervention to Reverse Frailty and Enhance Resilience Through Exercise and Education
Resistance training done at home and protein supplementation may be the most effective and easiest to implement interventions to reverse frailty and build resilience.
- Trial name
- REFEREE (NCT04628754)
- Testing
- Exercise and protein
- Where
- Ireland
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- University College Dublin