Clinical trials: Frailty, completed
Postoperative Delirium (POD), Frailty at Older Adults
Associations of Postoperative Delirium With Perioperative Frailty Worsening and Their Combined Effect on 1-Year Mortality in Older Surgical Patients
Postoperative delirium (POD) is a frequent complication in older surgical patients and is associated with adverse outcomes, while frailty is also highly prevalent during the perioperative period.
- Conditions
- Postoperative Delirium (POD), Frailty at Older Adults, Mortality, Recovery of Function
- Trial name
- NCT07259850
- Where
- China
- Volunteers
- 6,196 people
- Sponsor
- Chinese PLA General Hospital
Frail Elderly Syndrome, Cognitive Impairment
Investigating My Active and Healthy Aging
This is a multicenter, multicultural, randomized control trial. Participants will be recruited from 10 centers located in Italy, Germany, Austria, Spain, United Kingdom, Belgium, Sweden, Japan, South Korea and Australia.
- Conditions
- Frail Elderly Syndrome, Cognitive Impairment, Physical Dependence
- Trial name
- my-AHA (NCT03342976)
- Testing
- My-AHA platform
- Where
- Italy
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Fracture, Frailty
The CHARM Study-Coordinating Transitions from Hospital for Older Adults with Fractures
Background: Fall-related injuries like fractures are on the rise among older adults in New Brunswick. These injuries can lead to hospitalization and adverse health effects.
- Conditions
- Fracture, Frailty, Aging
- Trial name
- NCT06107699
- Testing
- Patient Navigation
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Horizon Health Network
Cognitive Deterioration
Pain Management in Elderly Patients With or Without Cognitive Frailty Hospitalized "ALGOGER"
Today, the standard treatment is to operate on patients suffering from a fracture of the upper end of the femur. The aim of treatment is to enable immediate mobilization and weight-bearing, and as rapid a return as possible to…
- Trial name
- ALGOGER (NCT06056934)
- Where
- France
- Volunteers
- 350 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Sarcopenia, Frailty
Sarcopenia Prevention With a Targeted Exercise and Protein Supplementation Program
Physical inactivity and protein malnutrition have been implicated to be key and modifiable causes of enhanced muscle mass loss among seniors.
- Conditions
- Sarcopenia, Frailty, Malnutrition; Protein, Fall
- Trial name
- STRONG (NCT03417531)
- Testing
- Protein Supplement, Protein-free Supplement, Active Exercise
- Where
- 2 sites in Switzerland
- Volunteers
- 801 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Frailty, Aging
AGE SELF CARE: Promoting Healthy Aging Through a Group Visit Program
Aim 1: To assess the feasibility and acceptability of delivering AGE SELF CARE through virtual medical group visits by measuring recruitment rate, adherence, and participant satisfaction.
- Conditions
- Frailty, Aging, Frailty Syndrome, Frail Elderly Syndrome
- Trial name
- NCT06079762
- Testing
- AGE SELF CARE group visit program
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Brigham and Women's Hospital
Cancer, Frailty
Qigong to Improve Frailty Among Older Cancer Survivors
The objective of the study is to examine the effects of a 16-week Baduanjin qigong intervention on frailty, physical performance, psychological well-being, and health-related quality of life (HRQoL) among post-treatment older…
- Conditions
- Cancer, Frailty, Survivorship, Elderly
- Trial name
- NCT04692233
- Testing
- Qigong Baduanjin, Light flexibility exercise
- Where
- 2 sites in Hong Kong
- Volunteers
- 226 people
- Sponsor
- The University of Hong Kong
Art, Wellness, Psychological
The Singapore Art-Health Study
The goal of the Singapore Art-Health RCT is to examine the effect of a standardized 12-week museum -based participatory art program on health condition, well-being, and quality of life in older community dweller, one that adheres…
- Conditions
- Art, Wellness, Psychological, Frailty, Quality of Life
- Trial name
- NCT05945589
- Testing
- Singapore A-Health Intervention
- Where
- Singapore
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Cirrhosis, Ascites
The BRAINFOOD Trial to Prevent Recurrent Hepatic Encephalopathy.
This study is being completed for patients with cirrhosis, including patients with a prior history of hepatic encephalopathy (HE) to evaluate the feasibility and benefits of medically-tailored meals as an intervention.
- Conditions
- Cirrhosis, Ascites, Liver Diseases, Frailty
- Trial name
- NCT04675775
- Testing
- Medically-tailored meals (MTM), Protein supplements, Nutrition education handout
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Michigan
Heart Disease, Physical Frailty
Genetics and Epidemiology of Aging Associated Conditions in the Sardinian Population
Background: The island of Sardinia, an Italian region, has a population that is highly interrelated. Researchers have developed the SardiNIA longitudinal study to examine the possible genetic factors that predispose individuals…
- Conditions
- Heart Disease, Physical Frailty, Exaggerated Personality Traits
- Trial name
- NCT00182949
- Where
- Italy
- Volunteers
- 6,926 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Diabetes, Type2 Diabetes
Electronic Frailty Index (eFI)Cacious-Diabetes Care
The purpose of this research is to explore whether a pharmacist-led diabetes management program can help optimize diabetes care for older adults.
- Trial name
- NCT05047237
- Testing
- Pharmacist-Led Optimization Intervention
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Wake Forest University Health Sciences
Multiple Myeloma
A Single-centre Prospective Study to Explore the Role of Frailty in Patients With Multiple Myeloma.
This study aims to explore the markers of frailty in a "real world" population of MM patients, and to monitor changes to those markers throughout treatment and follow-up.
- Trial name
- NCT04683393
- Volunteers
- 110 people
- Sponsor
- Manchester University NHS Foundation Trust
Social Isolation, Quality of Life
A 3-month Cycle of Virtual Guided Tours to Promote Health in Older Community Members in a Context of COVID-19 Induced Social Isolation: a Pilot Study
Social isolation is defined as the objective and/or subjective reduction of number and quality of interpersonal contacts leading to a loss of an individual's social role and stigmatization.
- Conditions
- Social Isolation, Quality of Life, Well Aging, Frailty
- Trial name
- VGV (NCT04593433)
- Testing
- Museum virtual guided tours
- Where
- Canada
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Jewish General Hospital
Postoperative Complications, Colorectal Cancer
Frailty Score and Postoperative Morbidity in Colorectal Cancer Surgery
This prospective observational study aims to evaluate the independent predictive value of the Edmonton Frailty Index (EFI) in estimating postoperative morbidity among older patients undergoing elective colorectal cancer surgery.
- Conditions
- Postoperative Complications, Colorectal Cancer, Frailty
- Trial name
- NCT06866678
- Testing
- Observational Data Collection
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Gastric Cancer, Frailty
Analysis of Influencing Factors of Preoperative Frailty in Elderly Patients With Gastric Cancer Based on the Health Ecology Theory
Frailty is common in patients with gastric cancer undergoing surgical treatment. Preoperative frailty can lead to many adverse outcomes in patients after surgery.
- Trial name
- NCT04929587
- Testing
- This is a observational research, there is no intervention
- Where
- China
- Volunteers
- 406 people
- Sponsor
- Nanjing Medical University
Aortic Stenosis
Frailty and Mortality in Older Old With Severe Aortic Stenosis
BACKGROUND.- The frailty syndrome (FS) associates an increase in morbidity and mortality in the elderly patient. When severe and symptomatic, aortic stenosis (AS) is a disease with poor prognosis, the most frequent cause of heart…
- Trial name
- SAS-frailty (NCT02745314)
- Testing
- Frailty measurement, Comprehensive Geriatric Assessment
- Where
- Spain
- Volunteers
- 605 people
- Sponsor
- Hospital de Meixoeiro
Lumbar Spinal Stenosis
Frailty and Associated Factors in Lumbar Spinal Stenosis
Lumbar spinal stenosis (LSS) is generally seen with advanced age, but it manifests itself with an increase in both physical and psychological health problems.
- Trial name
- NCT06959355
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people
- Sponsor
- Karabuk University
Frailty, Disability Physical
Functional Decline and QoL in People Aging with HIV in Asia
This is a multi-center prospective cross-sectional study to determine the burden of decline in intrinsic capacity and functional ability, and the prevalence of geriatric syndromes, such as frailty, and disability in adult people…
- Conditions
- Frailty, Disability Physical, HIV/AIDS
- Trial name
- NCT04212884
- Where
- 2 sites in Hong Kong
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Sarcopenia, Muscle Weakness
HORMA: Hormonal Regulators of Muscle and Metabolism in Aging
The purpose of this study is to determine the relationship of deficiencies in testosterone and growth hormone to loss of muscle mass (sarcopenia) and functional impairment during aging and whether there is an interaction of these…
- Conditions
- Sarcopenia, Muscle Weakness, Frailty
- Trial name
- NCT00183040
- Testing
- Topical testosterone, Recombinant human growth hormone
- Where
- 2 sites in United States
- Volunteers
- 108 people
- Sponsor
- National Institute on Aging (NIA)
Cardiac Surgery, Nutritional Risk
ERAS Compliance and Hospital Stay After Open Heart Surgery
This prospective observational study will evaluate the association between compliance with an Enhanced Recovery After Surgery (ERAS) protocol and length of hospital stay in 120 adults undergoing elective open heart surgery.
- Conditions
- Cardiac Surgery, Nutritional Risk, Frailty
- Trial name
- ERAS-CARD (NCT07783204)
- Testing
- ERAS Protocol Compliance Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Bursa City Hospital