Clinical trials: Freezing of Gait, open to volunteers
Parkinson Disease
Smartshoes for Freezing of Gait in Parkinson's Disease
This is a pilot research study aimed at evaluating whether an FDA listed wearable shoe with capability to deliver vibration feedback can be safe and tolerable for patients with Parkinson disease and control participants and…
- Trial name
- NCT07001072
- Testing
- Smartshoes with haptic vibration feedback
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Stanford University
Parkinson Disease
Function-based Accelerated Stimulation Therapy (FAST-therapy) for Freezing of Gait (FOG) After Parkinson's Disease (PD)
Parkinson disease (PD) is a common disorder in which reduced speed of movement results from inadequate brain production of the chemical dopamine.
- Trial name
- NCT05509842
- Testing
- rTMS
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Michigan
Parkinsons Disease (PD)
Neuroimaging of Parkinson's
Parkinson's Disease (PD) is a neurodegenerative disorder caused by dysfunction in both subcortical structures and the cortex. The investigators recently discovered a new brain system called the Somato-Cognitive Action Network…
- Trial name
- NCT07024875
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Parkinson Disease, Freezing of Gait Symptoms in Parkinson Disease
TURN-IT FOG: Improving Turning and Freezing of Gait in People With PD
The goals of this clinical trial are to 1) learn how two different rehabilitation interventions for PD can reduce Freezing of Gait (FOG) in people with Parkinson's disease, as assessed by patients, clinicians, and wearable…
- Trial name
- NCT06815302
- Testing
- Experimental intervention, Active intervention
- Where
- 3 sites in United States, Brazil
- Volunteers
- 60 people
- Sponsor
- Oregon Health and Science University
Parkinson Disease
Cue2Walk, Cost-effectiveness of Automated Freezing Detection and Provision of External Cues in Comparison to Usual Care in People With Parkinson's Disease
The majority of people with Parkinson's disease incur Freezing of Gait (FoG), which is not addressed adequately by medication. Cueing is a proven strategy to overcome FoG.
- Trial name
- NCT06416345
- Testing
- Cue2Walk, Usual Care
- Where
- 2 sites in Netherlands
- Volunteers
- 84 people
- Sponsor
- Amsterdam UMC, location VUmc
Freezing of Gait, Parkinson Disease
DBS and Levodopa for Treating Freezing of Gait in Parkinson's Disease
Freezing of gait (FoG) is a complex symptom of Parkinson's disease (PD) that cause falls and disability in PD patients, heavily affect patients' autonomy and quality of life.
- Trial name
- NCT06316232
- Testing
- STIM ON plus, MED ON plus
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- IRCCS Istituto delle Scienze Neurologiche di Bologna
Parkinson Disease, Idiopathic, Freezing of Gait
Vortioxetine for Depressive Symptoms and Freezing of Gait in Parkinson Disease
The present study involves patients with Parkinson Disease (PD) suffering from freezing of gait (FOG) and depressive symptoms. The main aim of the study is evaluating the efficacy of vortioxetine in reducing moderate/severe FOG…
- Conditions
- Parkinson Disease, Idiopathic, Freezing of Gait, Depression Not Otherwise Specified
- Trial name
- NCT06805266
- Testing
- Vortioxetine (tablet)
- Volunteers
- 40 people
- Sponsor
- Marianna Amboni
Freezing of Gait Symptoms in Parkinson Disease
A System to Help With Freezing of Gait in Parkinson's Patients
The goal of this clinical trial is to learn if the ParkinSense system, a customizable, multimodal, and adaptable cueing system, can assist with freezing of gait (FOG) in patients with Parkinson's disease.
- Trial name
- NCT07542743
- Testing
- ParkinSense System
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Barron Associates, Inc.
PD - Parkinson's Disease
Freezing of Gait - Clinical Outcomes Assessment
To develop a reliable and accurate clinician-reported outcome (ClinRO) measure (against a new and precise definition) and patient reported outcome (PRO) for use by clinicians and researchers to quantify the severity of Freezing…
- Trial name
- FOG-COA (NCT06519279)
- Testing
- Opals, Axivity
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Freezing of Gait, Parkinson Disease
Percept Transitions in FOG and PD
The purpose of this research is to examine the possible causes and signs of freezing of gait (FOG) secondary to Parkinson's disease (PD).
- Trial name
- NCT06848205
- Testing
- OFF Parkinson's Medication(s), OFF Deep Brain Stimulation
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Minnesota
Parkinson Disease, Freezing of Gait
Remote Mental Practice for Freezing of Gait in Parkinson's Disease
This single-blind, randomized controlled trial investigates the effects of a remotely delivered intervention based on mental practice (MP) combined with physical practice (PP) on freezing of gait (FOG) severity in people with…
- Trial name
- NCT06957405
- Testing
- MPPG (Mental and Physical Practice Group), PPG (Physical Practice Group)
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo General Hospital
Parkinson's Disease With Freezing of Gait
Validation of cueStim for Reduction of Freezing of Gait in Parkinson's Disease
The goal of this clinical trial is to learn if the cueStim device can reduce the duration of freezing of gait (FoG) that occurs in patients with Parkinson's Disease.
- Trial name
- NCT07675408
- Testing
- CueStim
- Where
- 6 sites in United States
- Volunteers
- 60 people
- Sponsor
- Fortis Medical Devices Limited
Parkinson Disease
Adaptive Deep Brain Stimulation for Freezing of Gait in Parkinson's Disease
The goal of this clinical trial is to learn if adaptive deep brain stimulation (DBS) can decrease or prevent freezing of gait in participants with Parkinson's disease.
- Trial name
- NCT06819020
- Testing
- Percept RC
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Doris Wang, MD, PhD
Parkinson Disease (PD)
Robotic Apparel to Prevent Freezing of Gait in Parkinson Disease
Freezing-of-gait (FoG) in Parkinson Disease (PD) is one of the most vivid and disturbing gait phenomena in neurology. Often described by patients as a feeling of "feet getting glued to the floor," FoG is formally defined as a…
- Trial name
- XF (NCT06602544)
- Testing
- Robotic Apparel
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Harvard Medical School (HMS and HSDM)
Parkinson Disease, Idiopathic, Freezing of Gait
AID-FOG: Artificial Intelligence-Driven Freezing of Gait Detection in the Home
Freezing of gait (FOG) is a debilitating symptom of Parkinson's disease increases the risk of falling. Despite being a common symptom, it is still difficult to evaluate freezing of gait quickly and accurately.
- Conditions
- Parkinson Disease, Idiopathic, Freezing of Gait, Validation, Wearable Sensors
- Trial name
- AID-FOG (NCT07580612)
- Where
- 3 sites in Belgium, Germany and 1 more
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Parkinson Disease, Freezing of Gait Symptoms in Parkinson's Disease
Brain-Machine Interface for Freezing of Gait
Gait problems in Parkinson's disease (PD), especially freezing of gait (FOG), greatly affect quality of life. While deep brain stimulation (DBS) is a highly effective treatment for many motor symptoms of PD, it is less effective…
- Trial name
- NCT06642519
- Testing
- Brain Stimulation
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of Toronto
Parkinson Disease, Freezing of Gait
Decoding the Neural Mechanisms Underlying Postural Instability and Gait Dysfunction in Parkinson's Disease
The purpose of this study is to learn how brain signals are related to freezing of gait (FOG) and balance problems in Parkinson's disease (PD) and to study how different deep brain stimulation (DBS) settings may affect these…
- Trial name
- NCT07748962
- Testing
- Multiple Deep Brain Stimulation (DBS) Conditions, Moving Overground in a Virtual Environment (MOVE), Cleveland Clinic Stair Ambulation and Functional Evaluation of Gait (SAFE-Gait)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- The Cleveland Clinic
Transcranial Direct Current Stimulation
Exploring the Possible Beneficial Impact of Non-invasive and Invasive Neuromodulation on Freezing of Gait in Parkinson's Disease During Different Ambulatory Complexities: An Electrophysiological and fMRI Study
Freezing of gait (FOG) stands out as a devastating symptom of Parkinson's disease (PD), where patients may become momentarily glued to the ground, rendering them incapable of walking efficiently.
- Trial name
- NCT06505460
- Testing
- Transcranial direct current stimulation
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Freezing of Gait, Parkinson's Disease
Etiology-Phenotype-Outcome Pathway Study on Freezing of Gait (FOG)
This study is a prospective, multicenter, observational cohort (patient registry) designed to better understand freezing of gait (FOG), a disabling walking problem that can occur in Parkinson's disease and other related…
- Conditions
- Freezing of Gait, Parkinson's Disease, Parkinsonism, Vascular Parkinsonism
- Trial name
- NCT07386015
- Testing
- Observational Data Collection
- Where
- China
- Volunteers
- 700 people
- Sponsor
- Tianjin Huanhu Hospital
Parkinson Disease, Gait Disorders, Neurologic
Correlation of STN-DBS Induced Visuospatial Changes and Freezing of Gait
The purpose of this research is to determine how deep brain stimulation (DBS) for Parkinson's disease affects attention and visuospatial function.
- Conditions
- Parkinson Disease, Gait Disorders, Neurologic, Visuospatial/Perceptual Abilities
- Trial name
- NCT06994728
- Testing
- Left STN-DBS on, right STN-DBS off first, Right STN-DBS on, left STN-DBS off first
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Medical University of South Carolina