Clinical trials: Frozen Embryo Pregnancy Rate
Infertility
Efficacy and Safety of Crinone Versus Combination Medication (ACCESS)
The study to compare to the efficacy and safety of Crinone versus combination medication in infertile women receive frozen-thawed embryo transfer (FET) in artificial cycles (AC).
- Trial name
- NCT03858049
- Testing
- Crinone, Duphaston
- Where
- China
- Volunteers
- 172 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Embryo Transfer, Luteal Support
Modified Luteal Support for Frozen-Thawed Embryo Transfer - A Prospective Study
This study evaluates the outcomes of frozen-thawed embryo transfer (FET) success rate with modified luteal support - addition of a single injection of HCG and GnRH-agonist, on day of ET and 4 days later, respectively vs.
- Trial name
- NCT02825290
- Testing
- Choriogonadotropin alfa, Triptorelin acetate
- Where
- Israel
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Infertility, Implantation
Impact of a Previous CS on the Ongoing Pregnancy Rate in Single Euploid Frozen Embryo Transfer (ET)
As embryo ploidy is a crucial factor not only for implantation but also for maintenance of a pregnancy, the aim of this study is to evaluate the impact of the CS / isthmocele on the ongoing pregnancy rates and the implantation…
- Trial name
- NCT05798624
- Testing
- Ultrasound between 6+0 and 6+7 weeks of pregnancy - With Isthmocele, Ultrasound between 6+0 and 6+7 weeks of pregnancy - Without Isthmocele, Ultrasound between 6+0 and 6+7 weeks of pregnancy
- Where
- United Arab Emirates
- Volunteers
- 1,050 people
- Sponsor
- ART Fertility Clinics LLC
Thin Endometrium, Female Infertility
Intrauterine G-CSF Infusion for Thin Endometrium
Thin endometrium is a condition in which the lining of the uterus is too thin during preparation for embryo transfer. This may reduce the chance of pregnancy and live birth in patients undergoing frozen-thawed embryo transfer.
- Trial name
- GIFT (NCT07692672)
- Testing
- Granulocyte Colony-Stimulating Factor(G-CSF), Normal Saline
- Volunteers
- 620 people
- Sponsor
- Nanjing University
Pregnancy Related, Infertility, Female
Comparison of Live Birth Rate in Natural Cycle Single Euploid FET Versus Without Luteal Phase Support
To evaluate whether single euploid embryo transfer in NC without routinely administered LPS is non-inferior to NC with routinely administered LPS.
- Trial name
- NCT05969795
- Testing
- Transvaginal ultrasound, Serial serum LH, E2, P4, Progesterone 100 Mg Vaginal Insert
- Where
- 3 sites in United Arab Emirates
- Volunteers
- 342 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Infertility, Female, Reproductive Techniques, Assisted
SISTER: Sibling Oocyte Insemination With Frozen Sperm From Third Party Donors: Evaluation of Reproductive Techniques
The goal of this clinical trial is to learn whether two different methods of helping eggs and sperm join-intracytoplasmic sperm injection (ICSI) and conventional in vitro fertilization (IVF)-lead to better embryo development when…
- Conditions
- Infertility, Female, Reproductive Techniques, Assisted, Fertilization in Vitro
- Trial name
- SISTER (NCT07175571)
- Testing
- Intracytoplasmic Sperm Injection (ICSI), Conventional Insemination (IVF)
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Shady Grove Fertility Reproductive Science Center
Ovarian Hyperstimulation Syndrome, Frozen-thawed Embryo Transfers
Association Between Live Birth Rate and Serum Progesterone During Hormonal Replacement Therapy
Nowadays, frozen-thawed embryo transfers (FET) are expending. This practice avoids risk of ovarian hyperstimulation syndrome (OHSS), as well as allowing better synchronization between endometrium and embryo, which is fundamental…
- Trial name
- PROGEVOL (NCT05588635)
- Testing
- Identification of predictive factors
- Where
- France
- Volunteers
- 168 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Infertility, Female
Traditional Chinese Medicine Herbs in the Freeze-all IVF Cycle
In the early stage, the preliminary study found that traditional Chinese medicine (TCM) intervention aimed at Nourishing kidney and regulating blood circulation in freeze-all IVF cycles can improve the clinical pregnancy rate.
- Trial name
- NCT04935073
- Testing
- Prescription of traditional Chinese Medicine named Er Zhi Wan combined with Si Wu Tang, Recombinant Human Follitropin Alfa for Injection、Fructose Injection、Tetyacycline Hydrochloride Capsules、Cetrorelix Acetate Powder for Injection
- Volunteers
- 90 people
- Sponsor
- Peking University Third Hospital
Infertility
Intrauterine Injection of Human Chorionic Gonadotropin Injection (hCG) Before Embryo Transfer on Pregnancy Outcomes in Frozen Embryo Transfer Cycles.
The present study is designed as a pilot study with 50 patients in each group. Data collection form will be filled by the researcher who does not know the type of intervention in each group
- Trial name
- NCT02825108
- Testing
- Intra uterine injection of tissue culture medium containing HCG+ET, Intra uterine injection of tissue culture medium +ET, ET
- Where
- Iran
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Royan Institute
Pregnancy
Serum Vitamin D Levels and Pregnancy Rates in Women Undergoing Elective Frozen Embryo Transfer (eFET)
The aim of this study is determining the affects of serum vitamin D levels to implantation and clinical pregnancy rates in women undergoing elective vitrified/thawed embryo transfer.
- Trial name
- NCT02361710
- Testing
- frozen embryo transfer
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Bahceci Clinic
IVF
Comparative Study Between Fresh and Frozen Embryo Transfer in PCOS Patients Undergoing IVF Treatment
The objective of our study is to compare in vitro fertilization (IVF) outcomes between fresh embryo transfer (ET) and frozen-thawed ET in women with polycystic ovary syndrome (PCOS).
- Trial name
- NCT05167838
- Testing
- fresh embryo transfer, Frozen embryo transfer
- Where
- Egypt
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Cairo University
IVF
The Effect of Sildenafil Citrate on Frozen Embryo Transfer Cycles
to investigate the value of adding sildenafil citrate during endometrial preparation in patients undergoing frozen-thawed embryo transfer and its effect on endometrial thickness and pregnancy rates.
- Trial name
- NCT05951413
- Testing
- Sildenafil Citrate, estradiol
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Beni-Suef University
Complications Associated With Artificial Fertilization, Placenta; Implantation
Effect of Assisted Hatching on Vitrified Embryo Transfer Clinical Outcome
The objective of study is to assess the possible impact of assisted hatching on the implantation, pregnancy rate and delivery rate after transfer of vitrified-warmed human embryos.
- Conditions
- Complications Associated With Artificial Fertilization, Placenta; Implantation, Pregnancy
- Trial name
- VitHatSZMC (NCT02124291)
- Testing
- Mechanical Assisted Hatching
- Where
- Israel
- Volunteers
- 18 people
- Sponsor
- Shaare Zedek Medical Center
Infertility, Female, Frozen Embryo Transfer
Luteal Phase Support During Frozen Embryo Transfer Cycle
We aimed to decrease quantity of exogenous estrogen and evaluated the success rate of ongoing pregnancy in women undergone artificial FET who have a surplus embryos at previous fertility treatment cycles.
- Trial name
- NCT04013438
- Testing
- Strogen
- Where
- Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Royan Institute
Infertility
SHorter Treatment of Replacement Therapy for Frozen Embryo Transfer (FET)
This is a Single-centre pilot study, randomized, controlled open-label trial with the aim to assess the clinical pregnancy rate and the early pregnancy loss rate between two different schemas for frozen embryo transfer cycles…
- Trial name
- ShoRT (NCT03930706)
- Testing
- Longer administration of estradiol (Progynova®)
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Universitair Ziekenhuis Brussel
Acupuncture, Female Infertility
Acupuncture in the Freeze-all IVF Cycle
In the early stage, our team found that Acupuncture intervention in freeze-all IVF cycles can improve the clinical pregnancy rate.
- Trial name
- NCT04931355
- Testing
- Acupuncture, Western medicine
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Peking University Third Hospital
Ivf, Frozen Embryo Transfer (FET)
Comparison of Pregnancy Rates in Modified Natural Frozen Embryo Transfer (FET) Cycle After Luteal Support with GnRH Agonist Versus Progesterone
Background: The capability to transfer frozen embryos reduces embryo loss following in vitro fertilization (IVF) and results in higher pregnancy rates compared to a single IVF cycle.
- Trial name
- NCT06870266
- Testing
- Nafarelin nasal spray, Utrogestan®
- Volunteers
- 150 people
- Sponsor
- Shaare Zedek Medical Center
Human Embryo Cryopreservation
Comparison Between Three Freezing Protocols to Preserve Human Embryos
This randomized study compares three different freezing methods to store human in vitro fertilization (IVF) embryos: vitrification with two commercial kits or slow freezing.
- Trial name
- NCT00910390
- Testing
- Slow freezing, VIT-Irvine, Vit-Vitrolife
- Where
- Belgium
- Volunteers
- 584 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital
Endometrial Disorder, Infertility, Female
Endometrial Compaction and Its Influence on Pregnancy Rate in Frozen Embryo Cycle Regimes
For a pregnancy to occur, an euploid embryo at blastocyst developmental stage, a receptive endometrium and the synchrony of both is crucial.
- Conditions
- Endometrial Disorder, Infertility, Female, IVF, Pregnancy Early
- Trial name
- NCT04454749
- Testing
- Blood test, Ultrasound
- Where
- United Arab Emirates
- Volunteers
- 3 people
- Sponsor
- ART Fertility Clinics LLC
Infertility (IVF Patients), Infertility Assisted Reproductive Technology
Estradiol 8 vs 12 mg for Endometrial Preparation in HRT-FET
The goal of this clinical trial is to learn whether 12 mg or 8 mg of oral estradiol valerate is better for preparing the endometrium in women undergoing hormone replacement frozen embryo transfer (HRT-FET) cycles.
- Conditions
- Infertility (IVF Patients), Infertility Assisted Reproductive Technology, Frozen Embryo Transfer (FET), Endometrial Preparation
- Trial name
- NCT07526207
- Testing
- Progynova®
- Where
- 2 sites in Egypt
- Volunteers
- 850 people
- Sponsor
- Cairo University