Clinical trials: Frozen Embryo Transfer, open to volunteers
Infertility, IVF
Immediate Versus Postponed Single Blastocyst Transfer in Programmed or Stimulated Cycle Frozen Embryo Transfer
The aim of this randomized controlled trial is to examine whether single blastocyst transfer in the first cycle after oocyte retrieval (immediate) is non-inferior to single blastocyst transfer in a subsequent cycle (postponed) in…
- Trial name
- NCT06304792
- Testing
- Immediate FET in a stimulated or programmed cycle
- Where
- Denmark
- Volunteers
- 484 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Embryo Transfer, IVF
Effect of Pentoxyfilline on Endometrial Thickness and Frozen Embryo Transfer Outcomes
The aim of this work was to investigate the effect of different vasodilators as pentoxifylline in women with unexplained infertility using IVF
- Conditions
- Embryo Transfer, IVF, Infertility
- Trial name
- NCT07499817
- Testing
- pentoxifylline 400 mg, (control)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Beni-Suef University
Chronic Endometritis
GnRH Agonist Pretreatment in Persistent Chronic Endometritis Undergoing FET
Women with PCE represent a treatment-resistant phenotype in whom the endometrial inflammatory and immune status remains abnormal despite antibiotic therapy.
- Trial name
- NCT07642700
- Testing
- Conventional estrogen-progesterone artificial cycle for endometrial preparation, GnRH agonist plus estrogen-progesterone for endometrial preparation
- Volunteers
- 150 people
- Sponsor
- Guoxia Yang
Embryo Transfer, Fertilization in Vitro
Does Sexual Intercourse Affect the Outcomes of Frozen-thawed Embryo Transfer?
The goal of this clinical trial is to test whether sexual intercourse the night after embryo transfer affects thawed embryo implantation rates.
- Conditions
- Embryo Transfer, Fertilization in Vitro, Coitus
- Trial name
- NCT06134609
- Testing
- Sexual intercourse
- Where
- Israel
- Volunteers
- 656 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Adenomyosis of Uterus, Frozen Embryo Transfer (FET)
GnRH Agonist Pretreatment Duration and Letrozole Supplementation in Frozen Embryo Transfer for Adenomyosis Patients
This randomized clinical trial aims to assess the comparative effectiveness of different pre-treatment protocols prior to frozen embryo transfer (FET) among women with adenomyosis, providing evidence-based guidance for clinical…
- Trial name
- GOLD-FET (NCT07065539)
- Testing
- GnRH-a-1M, GnRH-a-2M, GnRH-a+LE-1M
- Where
- China
- Volunteers
- 432 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Embryo Transfer, Hypertension, Pregnancy Induced
Treatment Preventive for Pre-eclampsia by Acetylsalicylic Acid in Women Who Underwent Frozen Embryo Transfer
Title: A prospective multicentric interventional randomized controlled trial to assess the effect of low dose acetylsalicylic acid as a preventive treatment of pre-eclampsia in pregnant women who underwent frozen embryo transfer
- Trial name
- TePPAFET (NCT05460416)
- Testing
- Acetylsalicylic acid
- Where
- Belgium
- Volunteers
- 276 people
- Sponsor
- Centre Hospitalier Universitaire de Liege
Infertility, Endometrial Peristalsis
Endometrial Peristalsis and Pregnancy Outcomes in Hormone Replacement Therapy (HRT) - Frozen Embryo Transfer (FET) Cycles
Endometrial peristalsis may influence embryo implantation and pregnancy outcomes, but its role during hormone replacement therapy (HRT)-prepared frozen embryo transfer (FET) cycles remains unclear.
- Conditions
- Infertility, Endometrial Peristalsis, Uterine Contraction, Endometrial Waves
- Trial name
- CONCO (NCT07675213)
- Testing
- Endometrial peristalsis and hormone measurements
- Where
- Vietnam
- Volunteers
- 442 people
- Sponsor
- Mỹ Đức Hospital
Assisted Hatching, Advanced Age
The Impact of Assisted Hatching on Pregnancy Outcomes After Vitrified-Warmed Embryo Transfer in Advanced-age Patients
The goal of this clinical trial is to evaluate the effect of laser assisted hatching (LAH) on pregnancy outcomes, with live birth rate as the primary outcome, in advanced age infertile women aged ≥35 years who are undergoing…
- Trial name
- NCT07490561
- Testing
- Laser assisted hatching
- Volunteers
- 916 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Recurrent Implantation Failure, Infertility
Comparing FET Guided by ERA Vs Standard Timing in Patients with Recurrent Implantation Failure
The pregnancy rate of in vitro fertilisation (IVF) remains around 35% per transfer. Women who are not pregnant following several embryo transfers are regarded as having recurrent implantation failure (RIF), with one of the causes…
- Trial name
- NCT06762626
- Testing
- Frozen embryo transfer according to endometrial receptivity analysis result
- Where
- China
- Volunteers
- 734 people
- Sponsor
- The University of Hong Kong
Tirzepatide, Frozen Embryo Transfer
Dual GIP/GLP-1 Receptor Agonist in Obese Women Before Frozen Embryo Transfer
To evaluate the efficacy and safety of Dual GIP/GLP-1 receptor agonist pretreatment on reproductive outcomes in obese women before frozen embryo transfer.
- Conditions
- Tirzepatide, Frozen Embryo Transfer, Obesity
- Trial name
- NCT07811895
- Testing
- Dual GIP/GLP-1 receptor agonist
- Where
- China
- Volunteers
- 1,510 people
- Sponsor
- RenJi Hospital
Subfertility
GnRH Agonist for Dual Trigger in IVF and for Luteal Phase Support in FET
The objectives of this study are to compare the efficacy of the dual trigger group vs the hCG trigger group on the live birth rate in women undergoing IVF and the efficacy of the agonist in LP group vs the placebo group on the…
- Trial name
- NCT04064840
- Testing
- IVF: Decapeptyl and hCG, FET: Decapeptyl, IVF: hCG and normal saline
- Where
- China
- Volunteers
- 784 people
- Sponsor
- The University of Hong Kong
Infertility Female, Frozen Embryo Transfer (FET)
FET-LET-2x2: Clinical Pregnancy Rates After Frozen Embryo Transfer in Natural and Modified Natural Cycles
The goal of this clinical trial is to learn whether different natural approaches to preparing the uterus for frozen embryo transfer (FET) can improve pregnancy success in women undergoing in vitro fertilization (IVF) treatment.
- Trial name
- FET-LET-2x2 (NCT07425990)
- Testing
- Letrozole (Aromatase Inhibitors), Choriogonadotropin alpha (r-hCG), Progesterone
- Where
- Serbia
- Volunteers
- 120 people
- Sponsor
- University of Novi Sad
Vitamin D Insufficiency, In Vitro Fertilization and Embryo Transfer
An Investigation of the Effect of Vitamin D Level During Frozen Embryo Transfer (FET) in IVF and Pregnancy Outcomes
Vitamin D is best known for keeping our bones healthy, but growing research suggests it may also play a role in fertility. Many In vitro fertilization (IVF) clinics now routinely check vitamin D levels and prescribe supplements…
- Trial name
- VitD in FET (NCT07681115)
- Testing
- No Intervention: Observational Cohort
- Where
- United Arab Emirates
- Volunteers
- 126 people
- Sponsor
- Fakih IVF Fertility Center
IVF, Infertility, Female
Effect of Tadalafil on Endometrial Thickness and Frozen Embryo Transfer Outcomes
investigate the effect of different vasodilators as Tadalafil in women with unexplained infertility using IVF
- Trial name
- NCT07499804
- Testing
- Tadalafil 5mg, estradiol valerate 2 mg
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Beni-Suef University
Infertility (IVF Patients)
Human Menopausal Gonadotropin Research in Infertility Assessing Cumulative Live Birth With Frozen Embryo Transfer.
The goal of this multicenter, randomized, placebo-controlled, double-blind clinical trial is toto evaluate the efficacy and safety of a human menopausal gonadotropin (hMG) in the development of multiple follicles, pregnancy, and…
- Trial name
- GRACE (NCT07216742)
- Testing
- hMG subcutaneous injection
- Where
- 16 sites in United States
- Volunteers
- 659 people
- Sponsor
- Granata Bio Corporation
Polycystic Ovary Syndrome
IVM With Low Cost Priming, Enhanced Oocyte Recovery, and Delayed Transfer
A protocol was developed to improve pregnancy results after IVM compared to results from studies in the literature. Differences from most published protocols include the use of the Steiner-Tan needle to optimize oocyte…
- Trial name
- IVMprt (NCT04149496)
- Testing
- in vitro maturation of oocytes
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Bruce Rose, MD
Embryo Transfer
Triggering Ovulation at Follicle Size Smaller or Larger Than 17mm in a Modified Natural Cycle
The rise in frozen embryo transfer (FET) cycles within assisted reproductive technology (ART) has sparked the need to refine endometrial preparation protocols.
- Trial name
- 17FET (NCT07088952)
- Testing
- Trigger at smaller folicular size
- Where
- Spain
- Volunteers
- 572 people
- Sponsor
- Vida Recoletas Sevilla
Luteal Support, Frozen Embryo Transfer (FET)
Is There a Need for Luteal Support in Modified Natural Cycle Frozen Embryo Transfer Cycles
Without progesterone there is no pregnancy. Following ovulation, the endocrine function of the follicle changes and progesterone replacing estradiol becomes its main secretory product.
- Trial name
- NCT06875752
- Testing
- no luteal support, Vaginal Progesterone, Progesterone plus HCG
- Where
- 5 sites in Hungary
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Dunamenti REK Istenhegyi IVF Center
IVF Outcomes
Comparison of Two Protocols in Frozen Embryo Transfer
This randomized clinical trial evaluates two different endometrial preparation protocols-hormone replacement therapy (HRT) and natural cycle-for frozen embryo transfer (FET) in infertile women undergoing assisted reproductive…
- Trial name
- NCT07003373
- Testing
- hormone replacement therapy (HRT) group
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Malihe Mahmoudinia
Preimplantation Genetic Testing (PGT), Frozen Embryo Transfer Cycle
Effects of Trophectoderm (TE) Biopsy on the Health and Development of Children Born After Preimplantation Genetic Testing (PGT) Cycles.
This study aims to investigate the effects of trophectoderm (TE) biopsy on the health and development of children born after preimplantation genetic testing (PGT) cycles.
- Conditions
- Preimplantation Genetic Testing (PGT), Frozen Embryo Transfer Cycle, Assisted Reproduction Technologies, Postnatal Health
- Trial name
- NCT07349966
- Testing
- Questionnaire
- Where
- Italy
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele