Clinical trials: Frozen Embryos
Fertilization in Vitro, Embryo Transfer
Immediate Versus Delayed FET Following a Stimulated IVF Cycle
Information regarding the optimal timing for frozen-thawed embryo transfer (FET) following a stimulated in vitro fertilization (IVF) is lacking.
- Trial name
- NCT03201783
- Testing
- immediate frozen-thawed embryo transfer, delayed frozen-thawed embryo transfer
- Where
- China
- Volunteers
- 724 people
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
Infertility, Female
Personal FET in RIF Patients According to Histological Dating of Endometrial of Natural/ Hormone Replacement Cycle
At present, the evaluation criterion of endometrial receptivity is controversial. The development of a molecular diagnostic tool, the endometrial receptivity array (ERA) for diagnosis of endometrial receptivity .
- Trial name
- NCT03312309
- Testing
- personal embryo transfer
- Where
- China
- Volunteers
- 155 people
- Sponsor
- Reproductive & Genetic Hospital of CITIC-Xiangya
Endometrium
The Effect of Tamoxifen on Clinical Outcome in Women With Thin Endometrium Undergoing Frozen Thawed Cycle.
Cryopreservation of embryos created during fresh IVF cycles provides a less expensive and time-intensive opportunity for pregnancy. Ideal endometrium thickness is the key point to optimization FET cycle.
- Trial name
- NCT03060304
- Testing
- Tamoxifen, estradiol valerate
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Infertility
SHorter Treatment of Replacement Therapy for Frozen Embryo Transfer (FET)
This is a Single-centre pilot study, randomized, controlled open-label trial with the aim to assess the clinical pregnancy rate and the early pregnancy loss rate between two different schemas for frozen embryo transfer cycles…
- Trial name
- ShoRT (NCT03930706)
- Testing
- Longer administration of estradiol (Progynova®)
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Universitair Ziekenhuis Brussel
Recurrent Implantation Failure, Infertility
Comparing FET Guided by ERA Vs Standard Timing in Patients with Recurrent Implantation Failure
The pregnancy rate of in vitro fertilisation (IVF) remains around 35% per transfer. Women who are not pregnant following several embryo transfers are regarded as having recurrent implantation failure (RIF), with one of the causes…
- Trial name
- NCT06762626
- Testing
- Frozen embryo transfer according to endometrial receptivity analysis result
- Where
- China
- Volunteers
- 734 people
- Sponsor
- The University of Hong Kong
Infertility
The PrISICE Clinical Trial (Pre-Implantation Screening and Investigation on the Cryopreservation of Embryos)
The trial objective is to determine whether the deferred transfer of embryos following cryopreservation at the blastocyst stage following pre-implantation genetic screening (PGS-FET) improves live birthrates compared to both the…
- Trial name
- PrISICE (NCT03371745)
- Testing
- Trophectoderm biopsy, Cryopreservation, Embryo Transfer
- Where
- 3 sites in United States
- Volunteers
- 32 people
- Sponsor
- Yale University
Infertility
Study Comparing Outcomes Between Conventional IVF and a "Freeze-all"-Strategy in Assisted Reproductive Technology
The purpose of this study is to compare conventional fresh embryo transfer with a "freeze all and transfer later strategy" in assisted reproductive technology in terms of ongoing pregnancy rates, live birth rates as well as…
- Trial name
- NCT02746562
- Testing
- Freeze all
- Where
- 2 sites in Denmark
- Volunteers
- 424 people
- Sponsor
- Anja Bisgaard Pinborg
Infertility, Female
Deferred Versus Fresh Embryo Transfers
Controlled ovarian stimulation (COS) enhances the efficacy of ART (Assisted reproductive technology) by permitting multiple-oocyte yields, but also alters endometrial receptivity (ER) by an advancement of endometrial development…
- Trial name
- DEFETOSE (NCT03349905)
- Testing
- fresh transfer, Deferred-frozen embryo transfer
- Where
- France
- Volunteers
- 237 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pregnancy
Idealizing Pregnancy Outcome With Single Blastocyst Transfer in a FET Cycle
Single embryo transfer (SET) has been advocated as a means of reducing the risk of multiple pregnancies, but has meant a reduction in pregnancy risk per embryo transfer.
- Trial name
- NCT01987856
- Testing
- Blastocyst morphology
- Where
- Turkey (Türkiye)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Antalya IVF
Acupuncture, Female Infertility
Acupuncture in the Freeze-all IVF Cycle
In the early stage, our team found that Acupuncture intervention in freeze-all IVF cycles can improve the clinical pregnancy rate.
- Trial name
- NCT04931355
- Testing
- Acupuncture, Western medicine
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Peking University Third Hospital
In Vitro Fertilization, Frozen Embryo Transfer
Comparison of Thawing Embryos in Advance and on the Day of Transfer on Pregnancy Outcomes in FET Cycle
Respectively for patients with repeated transplant failure and routine patients, Thawing frozen embryos in advance (18h) to extend the duration of embryonic development or thawing embryos on the day of transfer in the frozen…
- Trial name
- NCT04455191
- Testing
- Thawing Embryos in Advance, Thawing Embryos on the Day of Transfer
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Jinan Central Hospital
Embryo Implantation
Nifedipine Treatment on Uterine Contractility in IVF
The main factors associated with pregnancy rate in In Vitro Fertilization (IVF) treatment are embryo quality and the uterine ability to accept the embryo for implantation.
- Trial name
- NCT02072291
- Testing
- Nifedipine
- Where
- Israel
- Volunteers
- 90 people
- Sponsor
- Hadassah Medical Organization
Infertility
Efficacy and Safety of Crinone Versus Combination Medication (ACCESS)
The study to compare to the efficacy and safety of Crinone versus combination medication in infertile women receive frozen-thawed embryo transfer (FET) in artificial cycles (AC).
- Trial name
- NCT03858049
- Testing
- Crinone, Duphaston
- Where
- China
- Volunteers
- 172 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Polycystic Ovary Syndrome, Infertility, Female
GnRH Agonist Plus Hormone Replacement Therapy vs Hormone Replacement Therapy on IVF Outcomes
The study is conducted at Arash Women's Hospital on all women undergoing the frozen embryo transfer cycle. Patients who signed informed consent will be randomly divided into two groups.
- Trial name
- NCT05189873
- Testing
- Long GnRH agonist + HRT, HRT
- Where
- Iran
- Volunteers
- 128 people
- Sponsor
- Tehran University of Medical Sciences
Comparison of Pregnancy Rate (HCG+ Level) Obtained After a Replacement Embryonic in Spontaneous Cycle and Following Protocol "NPP". Comparison
Prospective Randomized Non-Inferiority Study Comparing Natural Cycle Frozen Embryo Transfer (NC-FET) to a New Type of Endometrial Preparation for FET: Natural Proliferative Phase (NPP-FET)
Frozen embryo replacement cycle :Two methods traditionally used: the spontaneous cycle and the artificial cycle.Now, Emergence of new protocols: NPP-FET or "Natural proliferative phase - frozen embryo transfer" Demonstrate…
- Trial name
- NPP (NCT06859944)
- Testing
- Embryo transfer
- Where
- Belgium
- Volunteers
- 272 people
- Sponsor
- Erasme University Hospital
Pregnancy Rate
Luteal-Phase GnRH Agonist Administration in Frozen-Thawed IVF Embryo Transfer Cycles
Supraphysiological hormonal stimulation enables collecting many oocytes in an In-Vitro Fertilization treatment, but may have a negative effect on uterine function and contribute the fact that the majority of preembryos placed in…
- Trial name
- NCT00542126
- Testing
- Decapeptyl 0.1 mg after embryo transfer
- Where
- Israel
- Sponsor
- Shaare Zedek Medical Center
Infertility, Female, Frozen Embryo Transfer
Luteal Phase Support During Frozen Embryo Transfer Cycle
We aimed to decrease quantity of exogenous estrogen and evaluated the success rate of ongoing pregnancy in women undergone artificial FET who have a surplus embryos at previous fertility treatment cycles.
- Trial name
- NCT04013438
- Testing
- Strogen
- Where
- Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Royan Institute
Infertility, Polycystic Ovarian Syndrome
HRT Versus MOS for Endometrial Preparation Prior to FET in PCOS Patients
Evaluation of endometrial preparation using either hormonal therapy or ovarian stimulation prior to frozen-thawed embryo transfer (FET) in patients with polycystic ovarian syndrome (PCOS)
- Trial name
- NCT02273791
- Testing
- Estradiol valerate, Sequential Clomiphene citrate and Gonadotropin
- Where
- 2 sites in Egypt
- Volunteers
- 126 people
- Sponsor
- Mansoura University
hCG, FET
Administration of Human Chorionic Gonadotrophin Before Secretory Transformation of Frozen-thawed Embryo Transfer Cycles
Successful embryo implantation is complicated process that requires synchrony between good-quality embryos and receptive endometrium.
- Conditions
- hCG, FET, Frozen-thawed Embryo Transfe, Human Chorionic Gonadotrophin
- Trial name
- NCT05340010
- Testing
- Human Chorionic Gonadotrophin Intramuscular injection 10.000 IU
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Alexandria University
Infertility, IVF
Optimization of Frozen Embryo Transfers by Studying Progesterone on the Day of Transfer
The number of embryo transfers after freezing has increased over the last 10 years due to improvements in embryo freezing techniques and in particular the development of vitrification.
- Trial name
- OTEC (NCT04290520)
- Testing
- bioassay
- Where
- France
- Volunteers
- 115 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes