Clinical trials: Frozen Embryos
Infertility, Frozen Embryo Transfer (FET)
Platelet-Rich Plasma vs. Granulocyte Colony-Stimulating Factor vs. Placebo and Outcomes in Frozen Embryo Transfer
The goal of this clinical trial is to assess the impact of using Platelet-Rich Plasma (PRP) vs. Granulocyte Colony-Stimulating Factor (GCSF) vs.
- Trial name
- NCT03945812
- Testing
- Granulocyte Colony Stimulating Factor, Platelet Rich Plasma Arm, Saline
- Where
- Egypt
- Volunteers
- 665 people
- Sponsor
- Wael Elbanna Clinic
Clinical Pregnancy
Immediate Versus Delayed Natural Cycle Frozen Embryo Transfers
Introduction: Based on recent studies the suggestion is that natural cycle frozen embryo transfers (NC FET) should preferably be used, with evidence suggesting that artificial cycle FET (AC FET) is subject to increased risks of…
- Trial name
- FET (NCT05215119)
- Testing
- natural cycle endometrial preparation
- Where
- Turkey (Türkiye)
- Volunteers
- 818 people, healthy volunteers welcome
- Sponsor
- Antalya IVF
in Vitro Fertilization
Transfer of Frozen Embryos in Natural Cycle: Evaluation of Impact of Spontaneous Versus HCG-triggered Ovulation on Pregnancy Rate
The purpose of the study is to evaluated whether there is a difference in pregnancy rate when transferring frozen embryos between patietns having spontaneously ovulated versus those triggered to voulate with HCG.
- Trial name
- TECNAT (NCT03428165)
- Testing
- HCG
- Where
- 2 sites in France
- Volunteers
- 103 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Infertility, Female Infertility
the Effect of Endometrial Compaction Caused by Progesterone Effect on Pregnancy Outcomes
The purpose of this prospective cohort study is to assess the effect of endometrial compaction caused by progesterone effect on pregnancy outcomes
- Conditions
- Infertility, Female Infertility, Frozen-thawed Embryo Transfer
- Trial name
- NCT04733235
- Testing
- Progesterone
- Where
- Turkey (Türkiye)
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Embryo Transfer, Hypertension, Pregnancy Induced
Treatment Preventive for Pre-eclampsia by Acetylsalicylic Acid in Women Who Underwent Frozen Embryo Transfer
Title: A prospective multicentric interventional randomized controlled trial to assess the effect of low dose acetylsalicylic acid as a preventive treatment of pre-eclampsia in pregnant women who underwent frozen embryo transfer
- Trial name
- TePPAFET (NCT05460416)
- Testing
- Acetylsalicylic acid
- Where
- Belgium
- Volunteers
- 276 people
- Sponsor
- Centre Hospitalier Universitaire de Liege
Infertilities, Embryo Transfer
Impact of the Presence of the Corpus Luteum on Pregnancies Obtained Through Frozen Embryo Transfer(FET)
In pregnancies achieved through programmed frozen embryo transfer cycle (PC-FET) and modified natural frozen embryo transfer (mNC-FET), to determine whether there are differences in endothelial and placental function, maternal…
- Trial name
- LUTI (NCT06896617)
- Testing
- Estradiol + Progesterone, Ovitrelle ( Hcg 250 mcg)
- Where
- Spain
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- Fundacion Clinic per a la Recerca Biomédica
Infertility, Endometrial Peristalsis
Association Between Peri-Transfer Endometrial Peristalsis And Live Birth In Modified Natural Cycle Frozen Embryo Transfer: A Prospective Cohort Study
The uterus is a dynamic muscular organ that undergoes rhythmic, wave-like contractions known as endometrial peristalsis or endometrial waves.
- Conditions
- Infertility, Endometrial Peristalsis, Uterine Contraction, Endometrial Waves
- Trial name
- EPFE (NCT07358468)
- Testing
- Endometrial peristalsis and hormone measurements
- Where
- 2 sites in Vietnam
- Volunteers
- 384 people
- Sponsor
- Mỹ Đức Hospital
Infertility
Comparison of Frozen-thawed Embryo Transfers and Fresh Embryo Transfers With Whole Chromosome Analysis Using Next Generation Sequencing
The investigators propose to perform a clinical randomized trial to evaluate the effect of a frozen-thawed embryo transfer and a fresh embryo transfer on pregnancy and implantation rates; with the added benefit of a blastocyst…
- Trial name
- NCT02000349
- Testing
- PGD
- Where
- United States
- Volunteers
- 186 people
- Sponsor
- Reprogenetics
Subfertility
A Study of Human Chorionic Gonadotrophin as Luteal Phase Support in Frozen Embryo Transfer
A randomised trial on the use of luteal phase support in frozen-thawed embryo transfer cycles. The hypothesis of the study is that the use of luteal phase support with human chorionic gonadotrophin would increase the pregnancy…
- Trial name
- NCT01931384
- Testing
- Human chorionic gonadotrophin
- Where
- Hong Kong
- Volunteers
- 450 people
- Sponsor
- The University of Hong Kong
IVF
Serum Progesterone on the Day of Thawed Embryo Transfer and Pregnancy Rate After an Artificial Endometrial Preparation
To determine if different serum Progesterone levels on FET day are associated with different clinical pregnancy rates (CPR), and if increasing dosage of vaginal Progesterone in cases of lower serum Progesterone level on FET day…
- Trial name
- NCT04278508
- Testing
- Progesterone
- Where
- Israel
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Unrecognized Condition
Expression of Endometrium During Window of Implantation
The aim of this study was to investigate the expression of endometrium during window of implantation between natural cycles and artificial cycles.
- Trial name
- NCT05478616
- Where
- Taiwan
- Volunteers
- 3 people
- Sponsor
- Kaohsiung Veterans General Hospital.
IVF, Infertility, Female
Effect of Tadalafil on Endometrial Thickness and Frozen Embryo Transfer Outcomes
investigate the effect of different vasodilators as Tadalafil in women with unexplained infertility using IVF
- Trial name
- NCT07499804
- Testing
- Tadalafil 5mg, estradiol valerate 2 mg
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Beni-Suef University
Serum Progesterone Levels, Progesterone Supplementation
Effect of Intramuscular Progesterone Supplementation on Clinical and Ongoing Pregnancy Rates in Patients With Low Serum Progesterone Levels on the Day of Embryo Transfer in Artificial Frozen Cycles
The aim of this study is to investigate whether intramuscular progesterone supplementation will improve clinical pregnancy rates and ongoing pregnancy rates in patients with decreased serum progesterone levels on the day of…
- Conditions
- Serum Progesterone Levels, Progesterone Supplementation, Frozen Embryo Transfer, Clinical Pregnancy Rates
- Trial name
- NCT04837768
- Testing
- Twice-daily transvaginal progesterone supplementation, Twice-weekly intramuscular + Twice-daily transvaginal progesterone supplementation
- Where
- 2 sites in Egypt
- Volunteers
- 354 people
- Sponsor
- Cairo University
Infertility
A Study:the Different Outcomes Between Natural Cycle and Hormone Replacement Cycle in FET
There are three main cycle regimens used for endometrial preparation for frozen embryo transfer（FET）: natural cycles (NC) with/without ovulation triggering, hormone replacement therapy cycles (HRT) in which the endometrium is…
- Trial name
- NCT01780558
- Testing
- natural cycles, estradiol and progesterone
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Endometrial Preparation, Frozen Embryo Transfer
Effect of Adding Sildenafil to Protocol of Endometrial Preparation in Outcome of Frozen-thawed Embryo Transfer Cycles
The target of this study was an estimate the result of sildenafil on ultrasonographic endometrial thickness, endometrial pattern investigation estrogen level on the day of progesterone administration, Implantation rate and…
- Trial name
- sildenafil (NCT01668446)
- Testing
- Sildenafil, estradiol valerat
- Where
- Iran
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- farzaneh hojjat
Polycystic Ovary Syndrome (PCOS), In Vitro Maturation of Oocytes
IVM - Fresh ET (THE SAIGON PROTOCOL) Versus IVF - FET in PCOS Women
Assisted Reproductive Technologies (ART) aim to increase success rates while minimizing patient risks. For women with high AFC or PCOS, conventional IVF carries a high risk of OHSS (Ho et al., 2019).
- Conditions
- Polycystic Ovary Syndrome (PCOS), In Vitro Maturation of Oocytes, Fresh Embryo Transfer
- Trial name
- SAIGON-PTC (NCT07171970)
- Testing
- IVM-Fresh (No gonadotropin + Fresh embryo transfer), IVF-FET (GnRH-Antagonist - Agonist Trigger - Frozen embryo transfer)
- Where
- Vietnam
- Volunteers
- 600 people
- Sponsor
- Mỹ Đức Hospital
Complications Associated With Artificial Fertilization, Placenta; Implantation
Effect of Assisted Hatching on Vitrified Embryo Transfer Clinical Outcome
The objective of study is to assess the possible impact of assisted hatching on the implantation, pregnancy rate and delivery rate after transfer of vitrified-warmed human embryos.
- Conditions
- Complications Associated With Artificial Fertilization, Placenta; Implantation, Pregnancy
- Trial name
- VitHatSZMC (NCT02124291)
- Testing
- Mechanical Assisted Hatching
- Where
- Israel
- Volunteers
- 18 people
- Sponsor
- Shaare Zedek Medical Center
Infertility
Electro-acupuncture and Assisted Reproductive Technology
One of the most widely used procedures in reproductive medicine technologies is In Vitro Fertilization (IVF). During the IVF procedure, there are sometimes unused embryos that are frozen to be used at later times.
- Trial name
- NCT01481090
- Testing
- Acupuncture, Electro-Acupuncture
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- National University of Health Sciences
Fertility Disorders
Assessment of the New Automated Vitrification System "GAVI" for Early Cleaved Embryos Cryopreservation
The meta-analysis comparing the cryopreservation of human embryos by vitrification or slow-freezing suggested that more well design studies as randomized trials are necessary to identify the most successful method for…
- Trial name
- GAVI (NCT03478592)
- Testing
- reference technique, vitrification technique
- Where
- France
- Volunteers
- 423 people
- Sponsor
- University Hospital, Toulouse
Ovarian Hyperstimulation Syndrome, Pregnancy Related
Freeze All Strategy Versus Fresh Embryo Transfer After GnRH Analogue Trigger
Ovarian hyperstimulation syndrome (OHSS) is one of the most dangerous complications of assisted reproduction technology (ART), described in approximatively 3 to 10% of stimulation cycles although an underestimation of the real…
- Trial name
- NCT05362734
- Testing
- obstetric outcomes after fresh versus cryopreserved embryo transfer
- Volunteers
- 1,396 people
- Sponsor
- Istituto Clinico Humanitas