Clinical trials: Frozen Thawed Embryo Transfer
Infertility, Embryo Transfer
Progesterone as Luteal Support in Frozen IVF Natural Cycles
The ProFET study aims to investigate if luteal phase support by vaginal progesterone, is superior to no luteal phase support, in terms of live birth rate per woman after a frozen embryo transfer (FET), in a natural cycle (NC)…
- Trial name
- ProFET (NCT04725864)
- Testing
- Progesterone vaginal tablet
- Where
- Sweden
- Volunteers
- 1,800 people
- Sponsor
- Vastra Gotaland Region
Infertility
Efficacy and Safety of Crinone Versus Combination Medication (ACCESS)
The study to compare to the efficacy and safety of Crinone versus combination medication in infertile women receive frozen-thawed embryo transfer (FET) in artificial cycles (AC).
- Trial name
- NCT03858049
- Testing
- Crinone, Duphaston
- Where
- China
- Volunteers
- 172 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Embryo Transfer, Luteal Support
Modified Luteal Support for Frozen-Thawed Embryo Transfer - A Prospective Study
This study evaluates the outcomes of frozen-thawed embryo transfer (FET) success rate with modified luteal support - addition of a single injection of HCG and GnRH-agonist, on day of ET and 4 days later, respectively vs.
- Trial name
- NCT02825290
- Testing
- Choriogonadotropin alfa, Triptorelin acetate
- Where
- Israel
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Thin Endometrium, Female Infertility
Intrauterine G-CSF Infusion for Thin Endometrium
Thin endometrium is a condition in which the lining of the uterus is too thin during preparation for embryo transfer. This may reduce the chance of pregnancy and live birth in patients undergoing frozen-thawed embryo transfer.
- Trial name
- GIFT (NCT07692672)
- Testing
- Granulocyte Colony-Stimulating Factor(G-CSF), Normal Saline
- Volunteers
- 620 people
- Sponsor
- Nanjing University
Supervision of Pregnancy Resulting From In-vitro Fertilization
Optimal Planning of a Day 3 Cryopreserved(Frozen)-Thawed Embryo Transfer in a Natural Cycle With hCG Administration or After Spontaneous LH Peak?
The aim of the study is to determine whether spontaneous LH peak is superior to human chorionic gonadotropin before a transfer of a day 3 frozen embryo.
- Trial name
- PLUS (NCT02145819)
- Testing
- hCG, LH peak
- Where
- Belgium
- Volunteers
- 240 people
- Sponsor
- Universitair Ziekenhuis Brussel
FET
Reduced Oestrogen Dosage to Improve the Outcome of Frozen-thawed Embryo Transfer
This study is a single-center, randomized, controlled prospective study. Those who will recieve hormone replacement therapy-frozen thawed embryo transfer (HRT-FET) are enrolled in the study.
- Trial name
- NCT05545592
- Testing
- Low oestrogen dosage
- Where
- China
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- Nanjing University
Ovarian Hyperstimulation Syndrome, Frozen-thawed Embryo Transfers
Association Between Live Birth Rate and Serum Progesterone During Hormonal Replacement Therapy
Nowadays, frozen-thawed embryo transfers (FET) are expending. This practice avoids risk of ovarian hyperstimulation syndrome (OHSS), as well as allowing better synchronization between endometrium and embryo, which is fundamental…
- Trial name
- PROGEVOL (NCT05588635)
- Testing
- Identification of predictive factors
- Where
- France
- Volunteers
- 168 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
In Vitro Fertilization
Follow-up Protocol on the Outcome of Frozen-thawed Embryo Transfer Cycles From Clinical Trial P05690 (P05711)
Clinical trial objective is to collect the outcome of Frozen-Thawed Embryo Transfer (FTET) cycles performed after the embryos are cryopreserved in the base study P05690 in order to estimate the cumulative pregnancy rate for each…
- Trial name
- NCT00702546
- Testing
- corifollitropin alfa, recFSH (follitropin alfa), gonadatropin releasing hormone (GnRH) antagonist ganirelix
- Volunteers
- 102 people
- Sponsor
- Organon and Co
IVF, ICSI
Randomized Prospective Trial on the Use of Laser Assisted Hatching (LAH) for Transfer of Frozen/Thawed Embryos in Human IVF/ICSI
At the time of transfer of frozen/thawed embryos in human IVF/ICSI, patients are randomized between study and control group.In the control group no additional intervention takes place on the embryos to be transferred,in the study…
- Trial name
- NCT00561249
- Testing
- laser assisted hatching
- Where
- Belgium
- Volunteers
- 293 people
- Sponsor
- University Hospital, Ghent
Miscarriage, Frozen Embryo Transfer
Natural Cycle Versus Hormone Replacement Therapy Cycle for a Frozen-thawed Embryo Transfer in PGT Patients
The aim of the current study is to compare miscarriage rates (before 8 weeks) between a true natural cycle (awaiting spontaneous LH surge) and a hormone replacement therapy cycle prior to blastocyst transfer in preimplantation…
- Conditions
- Miscarriage, Frozen Embryo Transfer, Natural Cycle, Hormone Replacement Therapy Cycle
- Trial name
- NCT03976544
- Testing
- Estradiol Valerate, Micronized progesterone
- Where
- Belgium
- Volunteers
- 362 people
- Sponsor
- CRG UZ Brussel
IVF
The Effect of Sildenafil Citrate on Frozen Embryo Transfer Cycles
to investigate the value of adding sildenafil citrate during endometrial preparation in patients undergoing frozen-thawed embryo transfer and its effect on endometrial thickness and pregnancy rates.
- Trial name
- NCT05951413
- Testing
- Sildenafil Citrate, estradiol
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Beni-Suef University
Thin Endometrium
Thin Endometrium Undergoing Frozen-thawed Embryo Transfer
The endometrium is essential for embryo implantation. The clinical pregnancy rate and live birth rate of patients with thin endometrium are significantly lower than those of normal endometrium.
- Trial name
- NCT04292886
- Testing
- Tamoxifen and femoston, Vitamin C and femoston
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Nanjing University
Subfertility
GnRH Agonist for Dual Trigger in IVF and for Luteal Phase Support in FET
The objectives of this study are to compare the efficacy of the dual trigger group vs the hCG trigger group on the live birth rate in women undergoing IVF and the efficacy of the agonist in LP group vs the placebo group on the…
- Trial name
- NCT04064840
- Testing
- IVF: Decapeptyl and hCG, FET: Decapeptyl, IVF: hCG and normal saline
- Where
- China
- Volunteers
- 784 people
- Sponsor
- The University of Hong Kong
Recurrent Implantation Failure
Zishen Yutai Pill for Patients With Recurrent Implantation Failure
The goal of this clinical trial is to evaluate the efficacy of Zishen Yutai Pill (ZYP) on pregnancy outcomes following embryo transfer and its safety in patients with recurrent implantation failure.
- Trial name
- NCT07641088
- Testing
- Zishen Yutai Pill
- Where
- 13 sites in China
- Volunteers
- 878 people
- Sponsor
- Peking University Third Hospital
Subfertility
A Study of Human Chorionic Gonadotrophin as Luteal Phase Support in Frozen Embryo Transfer
A randomised trial on the use of luteal phase support in frozen-thawed embryo transfer cycles. The hypothesis of the study is that the use of luteal phase support with human chorionic gonadotrophin would increase the pregnancy…
- Trial name
- NCT01931384
- Testing
- Human chorionic gonadotrophin
- Where
- Hong Kong
- Volunteers
- 450 people
- Sponsor
- The University of Hong Kong
In Vitro Fertilization
Follow-up Study of Frozen-thawed Embryo Transfer (FTET) Cycles After Cryopreservation of Embryos in Clinical Trial P05787 (P05716)
To collect the outcome of frozen-thawed embryo transfer cycles after the embryos are cryopreserved up to at least 1 year in Trial P05787 (NCT00696800), in order to estimate the cumulative pregnancy rate for each treatment group.
- Trial name
- NCT00702273
- Testing
- 150 µg Corifollitropin Alfa, 200 IU RecFSH/Follitropin beta (Days 1 to 7), 200 IU RecFSH/Follitropin beta (Days 8 to hCG)
- Volunteers
- 344 people
- Sponsor
- Organon and Co
Infertility
Subcutaneous Progesterone in Frozen- Thawed Single Euploid Blastocyst Transfer.
This is a multicenter, randomized, double-blind, double-dummy, active-controlled, non-inferiority clinical study in women aged 35 to 42 years.
- Trial name
- PROGRESS (NCT04549116)
- Testing
- Progesterone-IBSA Injectable Solution, Progesterone Vaginal Gel with Applicator
- Where
- 24 sites in United States
- Volunteers
- 688 people
- Sponsor
- IBSA Institut Biochimique SA
Infertility
Natural Cycle/Progesterone Fortified Protocol for Endometrial Preparation for Frozen/Thawed Embryo Transfer
This is a pilot study of a novel protocol for preparation of the endometrium for frozen/thawed embryo transfer whereby estrogen is not administered during the proliferative phase and progesterone is administered through vaginal…
- Trial name
- NCT02749344
- Testing
- FET after endometrial preparation
- Where
- Israel
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Infertility
Assesment of Embryo Viability and Re-expansion After Thawing in Blastocyst Stage Embryos
In this prospective study, the possible effects of embryo viability and degree of blastocele re-expansion on pregnancy outcomes before vitrified/thawed blastocyst transfer will be evaluated.
- Trial name
- NCT05474833
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Infertility
Frozen Embryo Transfer With GnRH-antagonist Trial
The fertility treatment in vitro fertilisation (IVF), sometimes including intra-cytoplasmic sperm injection (ICSI), involves the creation of embryos in a laboratory.
- Trial name
- NCT03763786
- Testing
- Cetrorelix Acetate
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- University of Oxford