Clinical trials: Function
Cognitive Function, Preclinical, Chronic Kidney Diseases
Exercise Training and Cognitive Function in Kidney Disease
Chronic kidney disease (CKD), affects over 45% of all individuals over 70 years of age. Patients with moderate CKD have more than a two-fold increased risk of cognitive impairment than those without CKD; furthermore, as many as…
- Conditions
- Cognitive Function, Preclinical, Chronic Kidney Diseases, Older Adults
- Trial name
- NCT03197038
- Testing
- Partially supervised home-based walking exercise, Control
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Chronic Non-Specific Low Back Pain, Cognitive Decline
The Impacts of Chronic Non-specific Low Back Pain on Cognitive Functions of Older Adults
Chronic non-specific low back pain (CNSLBP) is a prevalent condition among older adult and has been associated with an increased risk of executive function impairment.
- Conditions
- Chronic Non-Specific Low Back Pain, Cognitive Decline, Cross-Sectional Study, Older Adults
- Trial name
- NCT06704425
- Testing
- For observational studies, participants are not assigned an intervention as part of the study.
- Where
- 3 sites in Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Ocular Physiology, Regional Blood Flow
Effects of Topical Clonidine vs. Brimonidine on Choroidal Blood Flow and Intraocular Pressure During Isometric Exercise
Brimonidine tartrate is an alpha-2 agonist ocular hypotensive drug that exerts its effect by causing both a decrease in aqueous production and an increase in uveoscleral outflow.
- Trial name
- NCT00312416
- Testing
- Clonidin, Brimonidine
- Where
- Austria
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Healthy Young Adults
Comparison of Device Based Inspiratory Muscle Training and Thera-band Resistive Training in Healthy Adults
This study aims to evaluate the impact of inspiratory muscle training and Thera-band resistive training on pulmonary function and diaphragmatic strength of healthy adults.
- Trial name
- NCT06632847
- Testing
- IMT based Resistance training, Theraband Resistive training
- Where
- Pakistan
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Postsurgical Adhesion
Effects of Soft Tissue Mobilization on Postsurgical Adhesions, Pain, Lumbopelvic Muscle Functions, Spinal Mobility, and Posture in Postpartum Women With Caesarean Section
Postpartum women with C-section receiving deep and superficial tissue mobilization would have better improvement on pain, lumbopelvic muscle functions, spinal mobility, and posture compare to the superficial tissue mobilization…
- Trial name
- NCT05008315
- Testing
- Myofascial abdominal diaphragm release, Direct focused scar release technique, Direct manipulations to visceral structures
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- YI-JU TSAI
Endothelial Dysfunction
Centella Asiatica in Older Adults
The purpose of this study is to determine the effects of a dietary supplement containing centella asiatica on on vascular endothelial function in older adults.
- Trial name
- NCT06472791
- Testing
- Centella Asiatica
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- National University of Natural Medicine
Cannabis, Cardiovascular Risk Factor
Cannabis Inhalation: Effects on Cardiovascular Function During Rest and Exercise
This two-phase project seeks to examine the cardiovascular response to consumption of cannabis variants of different cannabinoid composition through different methods (smoking vs. vaporizing), at rest and during aerobic exercise.
- Trial name
- NCT04693884
- Testing
- Cannabis
- Where
- Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Jamie Burr
Alzheimer's Disease
Multi-modal Neuroimaging in Alzheimer's Disease IMAP+
Alzheimer's disease (AD) is a major public health problem due to its socio-economic weight. An early diagnosis of AD is urgently needed as it would constitute a determinant breakthrough from a social, financial and research…
- Trial name
- IMAP+ (NCT01638949)
- Testing
- Memory assessment, Circulating biomarkers measure, ApoE4
- Where
- 7 sites in France
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Hearing Impaired Children
Effects of Pilates and Balance Proprioception Exercises on Hearing Impairment
Static balance is the ability to hold the body in a specific position and posture, while dynamic balance is the ability to maintain balance while moving.
- Trial name
- NCT06198049
- Testing
- Pilates Training, Balance Proprioception Exercises
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Pregnancy Related
Effects of Foot Exercises and Hydrotherapy on Pedal Edema & Lower Extremity Function
To determine the Effects of foot exercises with and without hydrotherapy on pedal Edema \& lower extremity function in antenatal women.
- Trial name
- NCT05777538
- Testing
- hydrotherapy, foot exercises
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Irritable Bowel Syndrome
Effect of MethylceIlulose or Psyllium on Fermentation of Inulin Assessed Using a Gas Sensing Capsule
The investigators plan to measure the local (in vivo) production of hydrogen when methylcellulose is ingested, to see if the investigators can show a shift of the site of fermentation to the distal colon.
- Trial name
- REALISTIC (NCT06551948)
- Testing
- psyllium, methylcellulose, maltodextrin
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Physical Exertion
Acute Exercise and Microvascular Function
It is well recognized that chronic exercise protects against the development of cardiovascular diseases. However, the responses of vasculature to acute exercise (AE) are not well known and not consistent in literature.
- Trial name
- NCT02727439
- Testing
- Acute Exhausting Exercise (AE)
- Where
- Croatia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Josip Juraj Strossmayer University of Osijek
Cardiovascular Disease
Fitness and Daily Function in Adults
The purpose of this study is to examine the impact of aerobic fitness on the ability of able and disabled older adults to perform daily functional activities.
- Trial name
- NCT00018265
- Testing
- Task specific endurance training, Tai Chi
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Cocaine Dependence
Measuring Distress Tolerance With Functional MRI
Background: People who are in treatment for substance abuse often feel distress during the withdrawal period and afterward. Some individuals feel distress more acutely than others, and this distress has been linked to poor…
- Trial name
- NCT01038232
- Where
- 2 sites in United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
IUGR, Fetal Growth Retardation
Cardiac Displacement From Third Trimester to Early Childhood
The aim is to increase awareness of the relationship between (IUGR) and cardiac function in the foetus, the development of cardiac function over time after delivery and what significance a possible early disturbed myocardial…
- Conditions
- IUGR, Fetal Growth Retardation, Intrauterine Growth Restriction
- Trial name
- CADETTE (NCT02583763)
- Testing
- Echocardiography, Blood sample
- Where
- 2 sites in Sweden
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University Hospital, Linkoeping
Cognitive Function, Neuroplasticity
How Cultural Background Affects Cognitive and Motor Learning Using Virtual Reality
This observational study examined how long-term cultural background is associated with differences in cognitive and motor learning within a virtual reality environment.
- Conditions
- Cognitive Function, Neuroplasticity, Motor Skills, Virtual Reality
- Trial name
- NCT07242937
- Testing
- Virtual reality beat saber training and cognitive and motor assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Cognition - Other, Strength Outcomes
Effects of Alpha-GPC on Muscle Power, GH Levels, and Cognitive Function
Purpose: To determine the effects of low dose and high dose Alpha-GPC on cognitive performance, muscle performance, and serum growth hormone levels.
- Trial name
- NCT06690619
- Testing
- 315 mg Alpha-GPC, 630 mg Alpha-GPC
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Exostoses, Multiple Hereditary
Height, Ulnar Length and Forearm Function in Multiple Hereditary Exostoses
the purpose of the present registry is to describe the epidemiology of forearm deformities in patients with Hereditary Multiple Exostoses and to identify, independent predictors of severity of the disease and potential…
- Trial name
- NCT05914298
- Testing
- blood and buccal swab genetic test, PUL, Range of motion
- Where
- Italy
- Volunteers
- 408 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Physical Endurance, Muscle Strength
Combined Effects of Game Profile-based Training and Small-sided Games Among Football Players
Game profile-based training is a methodology in sports, including football, where training sessions are designed to simulate the specific conditions and challenges that players face during actual games.
- Conditions
- Physical Endurance, Muscle Strength, Functional Performance
- Trial name
- NCT06536816
- Testing
- Game Profile-based training Group, Small-sided games Group, Combined training Group with both Game Profile-based training and Small-sided Games
- Where
- Pakistan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Chronic Kidney Disease Stage 3B, Chronic Kidney Disease stage4
Physiopathology of Neuromuscular Function Related to Fatigue in Chronic Renal Disease
Chronic Kidney Disease (CKD) induces many metabolic troubles especially for the advanced CKD (stage 3b-5) patients and their prevalence and importance grow with the deterioration of the glomerular filtration rate (GFR).
- Conditions
- Chronic Kidney Disease Stage 3B, Chronic Kidney Disease stage4, Chronic Kidney Disease Stage 5, Fatigue
- Trial name
- PIONEER (NCT04330807)
- Testing
- Handgrip fatigability test, Questionnaires
- Where
- France
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier le Mans