Clinical trials: Functional Ability
Spinal Muscular Atrophy
Motor Function and Activity of Daily Life in Spinal Muscular Atrophy
This study will incorporate patients/ caregivers' perspectives to investigate the performance in daily activities of individuals with SMA and how it relates to their motor function abilities.
- Trial name
- NCT05931211
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Cognitive Deficits, Cognitive Ability, General
Childhood Anesthesia and Cognitive Function
The purpose of this study is to determine whether pediatric anesthesia is associated with long-term hippocampal dysfunction
- Trial name
- UCSF-Anes-01 (NCT01359215)
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Fall, Daily Activities
Incidence and Factors of Functional Decline After Emergency Department Discharge in Older Adults With Falls
The goal of this observational study is to learn about changes in activities of daily living (ADL) in older adults after being discharged from the emergency department (ED) following a fall.
- Conditions
- Fall, Daily Activities, Functional Decline, Older Adults (65 Years and Older)
- Trial name
- FALL-ADL (NCT07163715)
- Volunteers
- 280 people
- Sponsor
- Ege University
Stroke, Stroke Hemorrhagic
Task-Specific Self-Rehabilitation Training (TASSRET) Trial
The goal of this pilot RCT is to evaluate the effectiveness of a Task-specific Self-rehabilitation Training (TASSRET) program and compare the effect of the two formats of the TASSRET (video vs manual) on functional ability (upper…
- Conditions
- Stroke, Stroke Hemorrhagic, Stroke Ischemic, Hemiparesis After Stroke
- Trial name
- TASSRET (NCT07208422)
- Testing
- Video-based Task-specific Training, Manual-based Task-specific Training
- Where
- Nigeria
- Volunteers
- 50 people
- Sponsor
- National Assembly Clinic
Cognitive Ability, General
INSIGHT, A Comprehensive, Multidisciplinary Brain Training System
Adaptive reasoning and problem-solving are critical skills that allow for accurate decisions to be made based on varying levels of information.
- Trial name
- INSIGHT (NCT02780739)
- Testing
- Cognitive Training - 48 sessions, Fitness, Active Control
- Where
- United States
- Volunteers
- 521 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Stroke
Virtual Reality Exercise for Stroke Rehabilitation in Inpatients Who Are Unable to Stand
The purpose of this study is to determine if the addition of 10 to 12 sessions of sitting balance exercises using virtual reality training will provide additional gains in balance ability and function over standard inpatient…
- Trial name
- NCT02285933
- Testing
- virtual reality training, control
- Where
- Canada
- Volunteers
- 76 people
- Sponsor
- Bruyère Health Research Institute.
Ischemic Heart Disease
Diagnostic Performance and Prognostic Ability of the QFR
1. The primary technical endpoint was the diagnostic performance of the QFR against the FFR. 2. The primary clinical endpoint was target vessel failure (TVF) between two groups distributed by a QFR cut-off value of 0.8
- Trial name
- NCT04102917
- Testing
- QFR assessment
- Where
- South Korea
- Volunteers
- 915 people
- Sponsor
- Seoul St. Mary's Hospital
Individuals With Functional Limitations Which May Impact Their Forward Reach
Normative Biomechanical Measures of Reaching in Able-Bodied Adults
A study to obtain normative values and repeatability measures during functional reaching tasks in able-bodied individuals with no functional limitations.
- Trial name
- NCT05328947
- Testing
- Modified Functional Reach and Functional Reach
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Systemic Lupus Erythematosus, Arthralgia
The Impact of Exercise on Hand Function, Daily Activities Performance and Quality of Life of SLE' Patients
A total of 240 consecutive SLE patients fulfilling the SLICC classification criteria was evaluated. Sixty two patients who met the inclusion criteria were randomly assigned to the exercise group (n=32) or the control group…
- Trial name
- NCT03802578
- Testing
- HAND EXERCISE
- Where
- 2 sites in Greece
- Volunteers
- 62 people
- Sponsor
- National and Kapodistrian University of Athens
Spinal Cord Injuries, Spinal Cord Injury at C5-C7 Level
Multi-functional Neuroprosthetic System for Restoration of Motor Function in Spinal Cord Injury
This study is to evaluate the use of a fully implanted device for providing hand function, reach, and trunk function to individuals with cervical spinal cord injury. Funding Sources: FDA OOPD NIH NINDS
- Conditions
- Spinal Cord Injuries, Spinal Cord Injury at C5-C7 Level, Spinal Cord Injury Cervical, Spinal Cord Injury at C5-C7 Level With Complete Lesion
- Trial name
- NNP-UE+T (NCT02329652)
- Testing
- Networked Neuroprosthetic System for Grasp and Trunk
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Anne Bryden
Heart Failure
Heart Failure and Risk of Re-Admissions Determined by Abnormal REVEAL Parameters
The purpose of the Heart Failure and Risk of re-Admissions Determined by Abnormal REVEAL Parameters (HF RADAR) study is to evaluate the ability of cardiac rhythm (Cardiac Compass) data to predict future cardiac events in heart…
- Trial name
- HF-RADAR (NCT01357408)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Thomas Jefferson University
Stroke
Effects of Hemiplegic Shoulder Pain on Upper Extremity Motor Function, Trunk Control, Fear of Falling, Mobility and Indepence in Activities of Daily Living in Patients With Stroke
This study aimed to examine the effects of hemiplegic shoulder pain on upper extremity motor assessment, trunk control, fear of falling, mobility, and functional indepedence patients with stroke.
- Trial name
- NCT07559006
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Kutahya Health Sciences University
Patient Admission, Death
Intensive Care Unit (ICU) Admission Decisions in the Elderly : the ICE-CUB Study
Percentage of patients over 80 admitted in ICU varies greatly from one center to another. ICU admission criteria of older patients are scarcely described and benefit of ICU admission for those patients is uncertain.
- Conditions
- Patient Admission, Death, Activities of Daily Living
- Trial name
- IceCub (NCT00912600)
- Testing
- Intensive Care Unit admission
- Where
- France
- Volunteers
- 2,643 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Seasonal Allergic Rhinitis
Seasonal Allergic Rhinitis and Driving Ability
On-the-road driving performance of untreated seasonal allergic rhinitis patients during the allergic season (exposed) is compared to driving performance outside the allergic season (in winter, not-exposed).
- Trial name
- NCT00223587
- Testing
- 1 week of treatment discontinuation
- Where
- Netherlands
- Volunteers
- 22 people
- Sponsor
- Utrecht Institute for Pharmaceutical Sciences
Parkinson's Disease
Efficacy of Levodopa/Carbidopa/Entacapone vs Levodopa/Carbidopa in Parkinson's Disease Patients With Early Wearing-off
The study evaluated the efficacy of levodopa/carbidopa/entacapone vs levodopa/carbidopa in patients with Parkinson's disease and early wearing-off with levodopa
- Trial name
- NCT00391898
- Testing
- Levodopa/carbidopa/entacapone, Levodopa/carbidopa
- Where
- 26 sites in Spain
- Volunteers
- 95 people
- Sponsor
- Novartis
Type 2 Diabetes Mellitus (T2DM), Cognitive Function
Investigation of Motor Imagery Ability, Body Awareness and Cognitive Functions in Type 2 Diabetes Mellitus
The aim of this study is to examine the relationship between motor imagery skills, body awareness and cognitive functions in individuals with Type 2 Diabetes mellitus.
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Cognitive Function, Motor İmagery Ability
- Trial name
- NCT06588894
- Testing
- Questionnaire and Physical Exam, Motor Imagery Ability
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Kutahya Health Sciences University
Healthy Volunteer, Muscular Atrophy, Spinal
Ability of Muscle Imaging and Motor Function Measure (MFM) to Detect Changes in Disease Progression in Ambulant Spinal Muscular Atrophy Patients Compared to Healthy Volunteers.
This non-drug, single center, 24-week, longitudinal study in ambulant spinal muscular atrophy (SMA) patients and in age- and gender-matched healthy volunteers will assess the detection of disease progression by magnetic resonance…
- Trial name
- NCT02044029
- Where
- Switzerland
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Compression Fracture of Vertebral Body, Osteoporosis
Evaluation of Outcomes for Quality of Life and Activities of Daily Living for BKP in the Treatment of VCFs
The study objective is to collect and report 12-month outcomes pertaining to activities of daily living, quality of life, and safety parameters in a Medicare population to be treated with balloon kyphoplasty in the treatment of…
- Conditions
- Compression Fracture of Vertebral Body, Osteoporosis, Cancer
- Trial name
- EVOLVE (NCT01871519)
- Testing
- Balloon kyphoplasty
- Where
- 25 sites in United States
- Volunteers
- 354 people
- Sponsor
- Medtronic Spinal and Biologics
Lower Limb Amputation Knee, Lower Limb Amputation Above Knee (Injury)
Enhancing Abilities in Amputees and Patients With Peripheral Neuropathy Through Restoration of Sensory Feedback
Many amputees suffer from Phantom Limb Pain (PLP), a condition where painful perceptions arise from the missing limb. Leg amputees wear prostheses that do not provide any sensory feedback, apart from the stump-socket interaction.
- Conditions
- Lower Limb Amputation Knee, Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Below Knee (Injury), Diabetic Peripheral Neuropathy
- Trial name
- NCT04217005
- Testing
- Sensory Feedback
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- ETH Zurich
Hypoxia, COPD
Intelligent Oxygen Therapy During Activities of Daily Living
The aim of this study is to assess whether an auto-titrating oxygen system can maintain constant oxygen saturations (SpO2) in patients who are on long-term oxygen therapy (LTOT) during activities of daily living.
- Conditions
- Hypoxia, COPD, Hyperoxia
- Trial name
- NCT02683486
- Testing
- Intelligent oxygen therapy (an auto-titrating oxygen system), Long-term oxygen therapy
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- Imperial College London