Clinical trials: Functional Aging
Physical Activity, Physical Function
Structured Self-Talk and Wearable-Assisted Walking for Physical Activity and Function in Older Adults
The goal of this randomized clinical trial was to examine whether adding structured self-talk to wearable-assisted walking could support physical activity and physical function in community-dwelling older adults.
- Conditions
- Physical Activity, Physical Function, Healthy Aging
- Trial name
- NCT07767136
- Testing
- Moderate-Intensity Walking Program, Wearable Activity Device, Structured Self-Talk Training
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- CHENG-EN WU
Healthy Ageing
Blood Flow Restriction Cycling for Functional Mobility in Older Adults
This randomized, sham-controlled trial investigates whether a six-week, twice-weekly low-load cycling program combined with individualized blood flow restriction (BFR) improves functional mobility and health-related quality of…
- Trial name
- NCT07825987
- Testing
- Individualized Blood Flow Restriction (BFR) via Personalized Tourniquet System
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital, Bonn
Aging, Institutionalized Older Adults
Effects of Exercise, Cognitive Training, and Their Combination in Institutionalized Older Adults
The goal of this clinical trial is to learn if physical exercise, cognitive stimulation, or a combination of both can improve mobility, cognitive function, and psychosocial well-being in institutionalized older adults aged 65 and…
- Conditions
- Aging, Institutionalized Older Adults, Cognitive Abilities, Mobility and Independence
- Trial name
- NCT07082504
- Testing
- Physical Exercise Program, Cognitive Stimulation Program, Combined Physical Exercise and Cognitive Stimulation
- Volunteers
- 140 people
- Sponsor
- University of Salamanca
Aging, Mortality
Longevity Metrics AI/ML Development Study
This study builds AI models that score diagnostic screening tests, and that predict screening results, clinical judgment, and life expectancy.
- Conditions
- Aging, Mortality, Cardiovascular Disease Prevention, Metabolic Syndrome
- Trial name
- NCT07808619
- Testing
- AIML scored health screening battery
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.
Healthy Aging, Cognition
Effects of Cannabidiol on Memory and Attention in Adults Aged 60-70: A Pilot Study
This pilot study aims to investigate the effects of a single oral dose of cannabidiol (CBD) on memory and attention in healthy adults aged 60 to 70 years.
- Trial name
- CBD-MAP (NCT07910292)
- Testing
- Cannabidiol (CBD)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of Silesia
Exercise Intolerance, Aging
Heat Therapy and Muscle Function Study
Exercise tolerance decreases with age and a sedentary lifestyle. Muscle critical power (CP), is a sensitive measure of exercise tolerance that is more even more relevant to and predictive of endurance performance than VO2max.
- Conditions
- Exercise Intolerance, Aging, Heat Therapy, High Intensity Interval Training
- Trial name
- NCT04733287
- Testing
- High Intensity Interval Training of the Knee Extensors, Muscle Heat Therapy, Muscle Disuse
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Brigham Young University
Seniors, Old Age
Mental Effort During Low Load Resistance Training in Older Adults
The goal of this clinical trial is to determine the effect of maximal mental effort combined with low-intensity resistance training on strength and neuromuscular function in older adults.
- Conditions
- Seniors, Old Age, Sarcopenia
- Trial name
- NCT07687316
- Testing
- Low Intensity Resistance Training with Maximal Mental Effort, Low Intensity Resistance Training
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kennesaw State University
Aging, Type2 Diabetes
Cardiovascular Risk and Functional Responses From Dancing at Home in the Elderly With and Without Type 2 Diabetes
The goal of this randomized controlled trial is to investigate the effects of a dance intervention performed at home, on cardiovascular risk factors and functional capacity of elderly individuals with and without type 2 diabetes…
- Trial name
- NCT04840368
- Testing
- Dancing
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Aging, Cardiovascular Risk Factor
A Combined Multidomain Intervention to Prevent Cognitive Decline Associated With Cardiovascular Risk Factors.
The ACTIONcardioRisk trial is designed to investigate the effect of aerobic and progressive resistance training exercises combined with cognitive training, on neurocognitive functioning of sedentary older adults with and without…
- Trial name
- ACTIONcR (NCT04962061)
- Testing
- Cognitive Training, Aerobic and resistance exercises, Stretching and Toning
- Where
- Canada
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Louis Bherer
Aging Disorder, Aging Problems
Effects of Footwear Suitability on Functional Performance and Balance in Elderly
Proper footwear serves to protect the foot against external factors. Balance and functional performance are affected by the level of footwear suitability.
- Conditions
- Aging Disorder, Aging Problems, Aging
- Trial name
- NCT04151654
- Testing
- Footwear Assessment Score
- Volunteers
- 154 people
- Sponsor
- Tuba Maden
Aging
Optimal Exercise Training and Nutrition Supplementation in Older Men
As we age we tend to lose muscle mass and strength. These losses contribute to the increased incidence of falls and fractures, metabolic diseases such as type 2 diabetes, loss of independence and reduced quality of life in the…
- Trial name
- NCT02281331
- Testing
- Supplement
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- McMaster University
Cognitive Changes Due to Organic Disorder (Finding), Dementia
Gerontology Research Programme: The Singapore Longitudinal Ageing Studies (SLAS I & II)
The Gerontology Research Programme (GRP) in the National University Singapore's Department of Psychological Medicine, was formed to coordinate and facilitate the conduct of multi-disciplinary research on in a wide range of…
- Conditions
- Cognitive Changes Due to Organic Disorder (Finding), Dementia, Mild Cognitive Impairment, Frailty
- Trial name
- SLAS (NCT03405675)
- Testing
- SLAS 1, SLAS 2
- Where
- Singapore
- Volunteers
- 6,183 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Aging, Endothelial Dysfunction
Fisetin to Improve Vascular Function in Older Adults
This is a pilot clinical trial to test the efficacy of intermittent treatment with the flavonoid compound fisetin for improving vascular endothelial function and reducing aortic stiffness in older adults.
- Conditions
- Aging, Endothelial Dysfunction, Arterial Stiffness
- Trial name
- NCT06133634
- Testing
- Fisetin
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Aging
Power During Functional Tasks in Older Adults
The primary aim of this study is to optimize the methodology to measure lower limb power in older adults, so that clinicians are able to detect functional problems in this population earlier.
- Trial name
- NCT04019132
- Testing
- Muscle function test
- Where
- Belgium
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Longevity, Healthy Aging
Collagen Peptides and Cellular Aging
The goal of this clinical trial is to learn if daily collagen peptide supplementation can stabilize or lengthen telomeres and improve related markers of cellular aging in adults aged 50-70 years with overweight and…
- Conditions
- Longevity, Healthy Aging, Biological Ageing
- Trial name
- NCT07456449
- Testing
- Collagen peptides
- Where
- Austria
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Vienna
Aging
Functional Mobility in the Elderly: Influence of Morphological, Neuromuscular and Training Parameters
Life expectancy and elderly population are increasing. Health professionals try to provide longevity with good quality of life for this population, through the functional independence maintenance.
- Trial name
- NCT03206580
- Testing
- Concentric training, Concentric-Eccentric training
- Where
- Brazil
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
At Risk for AD-dementia, With Subjective Cognitive Decline, At Risk for Cognitive Decline
High-Velocity Resistance Training for Brain Blood Flow and Cognitive Function in Older Adults
The goal of this clinical trial is to learn whether a 12-week high-velocity resistance training program can improve brain blood flow and thinking skills in adults ages 60 to 79 who are at higher risk for Alzheimer's disease and…
- Trial name
- NCT07444554
- Testing
- High-Velocity Resistance Training
- Volunteers
- 60 people
- Sponsor
- University of Illinois Chicago
Subjective Cognitive Decline (SCD)
Cog-Fun Ageing Participation-centered, Health Promotion for Older Adults
The goal of this feasibility study is to test the feasibility of a group intervention program based on health management principles for older adults with Subjective Cognitive Decline (SCD).
- Trial name
- NCT06632145
- Testing
- Cog Fun Ageing intervention
- Where
- Israel
- Volunteers
- 11 people
- Sponsor
- Hebrew University of Jerusalem
Aging
Effect of Ankle Splinting on Vascular Function in Aging
Endothelial function of the skeletal muscle vasculature declines with advancing age. Although aerobic exercise training is commonly prescribed to combat loss of endothelial function in the elderly, the rate of compliance to…
- Trial name
- NCT02144896
- Testing
- Ankle splinting
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Florida
Aging
Effects of Resistance Training Programes At Different Intensities on Musculoskeletal, Metabolic, Lipid, Immunological, Inflammatory, Well-being and Functional Parameters in Older Adults.
The aging of the global population is recognized by the World Health Organization (WHO) as a major issue due to the disabilities and comorbidities related to this process, with women being the gender most affected.
- Trial name
- NCT06618469
- Testing
- Elastic band-based resistance training program at high intensity (HI), Elastic band-based resistance training program at moderate-high intensity (MHI-bands), Elastic band-based resistance training program at moderate intensity (MI)
- Where
- Spain
- Volunteers
- 320 people
- Sponsor
- University of Valencia