Clinical trials: Functional Aging
Oral Health of Older Men, Dietary Assessment of Older Men
Composition of Functional Tooth Units and Nutrient Intake in Older Men
Various definitions of poor dentition in older adults has been linked with inadequate intake of nutrients and poor diet quality.
- Trial name
- CHAMP (NCT03295435)
- Testing
- Composition of functional tooth units
- Where
- Australia
- Volunteers
- 781 people
- Sponsor
- University of Sydney
HIV
Strength Training and Endurance Exercise for LIFE
Research is needed to determine safe and effective exercise rehabilitation programs to prevent and improve physical disability in older adults living with HIV. This problem is of great importance to the VA.
- Trial name
- STEEL (NCT02101060)
- Testing
- exercise
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- VA Office of Research and Development
Sarcopenia
Effect Study of Marine Protein Hydrolysates to Prevent Loss of Muscle Mass and Physical Function in Frail Elderly
The purpose of this study is to determine whether a marine protein hydrolysate given as a supplement can prevent age related loss of muscle mass and loss of physical function in frail elderly.
- Trial name
- NCT02890290
- Testing
- Marine Protein hydrolysate
- Volunteers
- 92 people
- Sponsor
- Molde University College
Aging, Blood Pressure
Coconut Sugar Lowers Blood Pressure and Arterial Stiffness in Middle-aged and Older Adults
The goal of this intervention is to determine the efficacy of coconut sap powder (CSP) to lower arterial stiffness and blood pressure in middle-aged and older adults.
- Conditions
- Aging, Blood Pressure, Arterial Stiffness
- Trial name
- NCT05645991
- Testing
- Coconut Sap Powder (CSP)
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Ball State University
Menopause, Elevated Blood Pressure
Blueberries for Improving Vascular Endothelial Function in Postmenopausal Women With Elevated Blood Pressure
Postmenopausal women are at an increased risk of developing cardiovascular disease (CVD) largely due to accelerated aging-related modifications to vascular health following menopause.
- Conditions
- Menopause, Elevated Blood Pressure, Hypertension, Endothelial Dysfunction
- Trial name
- NCT03370991
- Testing
- Blueberry Powder
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Colorado State University
Aging, Asymmetry
Fall Risk in Adults Over 65: The Relevance of Morphological and Functional Lower Limb Asymmetries.
Falls among older adults represent a major public health burden. Approximately 30% of individuals aged 65 and older experience at least one fall each year.
- Conditions
- Aging, Asymmetry, Fall Risk Factors, Fall Prevention
- Trial name
- ASY&FALL (NCT07742397)
- Where
- Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Sleep Fragmentation, Poor Sleep Quality
Acupuncture for Sleep Fragmentation in Older Adults: A Single-Arm Pilot Study
This single-group pilot study will enroll 20 adults aged 60 years or older with persistent poor sleep. All participants will receive a standardized 6-week acupuncture program.
- Trial name
- NCT07841938
- Testing
- Acupuncture
- Where
- 2 sites in Taiwan
- Volunteers
- 20 people
- Sponsor
- Chang Gung Memorial Hospital
Aging
Optimizing Strength Training in Older Adults
The objective of the current study is to determine whether lifting lighter loads close to failure improves strength training adaptations and function in older adults. The main questions it aims to answer are: 1.
- Trial name
- LOAD (NCT06812143)
- Testing
- Strength training
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Queens College, The City University of New York
Transcranial Direct Current Stimulation
fMRI Analysis of Aging and Awareness in Conditioning
Cathodal Transcranial direct current stimulation (tDCS) was administered to the right parietal region in order to determine if this stimulation could disrupt awareness of the conditioned stimulus (CS) - unconditioned stimulus…
- Trial name
- NCT03655769
- Testing
- transcranial direct current stimulation
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Muscle Weakness, Low Muscle Mass
Muscle Aging Phenotypes in Childhood Cancer Survivors
Childhood cancer survivors experience premature declines in muscle mass, strength, and physical function that contribute to morbidity and early mortality.
- Conditions
- Muscle Weakness, Low Muscle Mass, Sarcopenia
- Trial name
- NCT07531498
- Testing
- Multimodal Muscle Imaging and Functional Assessment, Multimodal Muscle Imaging and Neuromuscular Assessment, Comprehensive Muscle Phenotyping
- Where
- United States
- Volunteers
- 533 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Mitochondrial Function, Physical Function
Resveratrol to Enhance Vitality and Vigor in Elders
Resveratrol, a compound found in red wine and dark-skinned grapes, will improve the function of mitochondria (energy producing components) within the leg muscles of moderate functioning older adults.
- Trial name
- REVIVE (NCT02123121)
- Testing
- Resveratrol 1000 mg/day, Resveratrol 1500 mg/day, Vegetable cellulose
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Florida
Disability, Intellectual
The Effectiveness of Baduajin in People With Intellectual Disability
Due to the ageing process, individuals with intellectual disability (ID) experience decreased balance and loss of functionality at an earlier age than their peers without ID.
- Trial name
- NCT05107973
- Testing
- Baduajin
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)
Aging, Physical Functioning
Implementing a Physical and Cognitive Performance Assessment Cohort in the MURDOCK Study Community Registry and Biorepository
The purpose of this study is to use the MURDOCK Horizon 1.5 infrastructure (Duke Instutional Review Board Pro00011196) to specifically target and enroll 1,000 participants across age groups and other demographic categories in…
- Conditions
- Aging, Physical Functioning, Cognitive Functioning, Fitness
- Trial name
- PPS (NCT01720472)
- Testing
- Biomarker studies
- Where
- 6 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Duke University
Sleep Disturbances, Depression
Neurobiological Investigations of Mindfulness, Depression and Sleep Disturbances in Medical Staffs and Community Elders
The research team proposes a multi-year study with the first year focusing on the developmental phase. In this initial phase, we aim to recruit 40 participants (including healthcare staff and older adults) from Shuang-Ho Hospital…
- Trial name
- NIMDS (NCT07179172)
- Testing
- Mindfulness-Based Stress Reduction (MBSR) 8-Week Program
- Where
- Taiwan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Sarcopenia, Physical Inactivity
Women in Action: A Multicomponent Intervention for Older Women
"Women in Action" is a quasi-experimental, mixed-methods study evaluating a 16-week multicomponent intervention (supervised strength/aerobic/balance training plus psychoeducational and nutrition-focused behavioral workshops) for…
- Conditions
- Sarcopenia, Physical Inactivity, Menopause, Healthy Aging
- Trial name
- WIA (NCT07860424)
- Testing
- Multicomponent exercise, nutrition, and psychoeducational program
- Where
- 2 sites in Spain
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Universidad de Oviedo
Dehydrated, Water-Electrolyte Imbalance, Malnutrition, Dehydration (Physiology)
Effects of Increased Water Intake on Hormonal Response, Hydration Status, and Physical Function in Low-drinking Older Adults
DrinkAge is a randomized controlled trial investigating whether increasing daily water intake can improve hydration and health-related outcomes in adults aged 60 years or older who habitually drink relatively little water.
- Trial name
- DrinkAge (NCT07892742)
- Testing
- Water
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Polytechnic University of Santarém
Women, Aging
Beta3-adrenergic Receptors and Cardiovascular Function in Aging Women
To determine if vascular beta3 adrenergic receptors are present and functional in aging women and can be targeted to attenuate sympathetic vasoconstriction and enhance vascular function in aging women.
- Conditions
- Women, Aging, Menopause
- Trial name
- NCT07674680
- Testing
- Gemtesa
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Ageing
Effectiveness of the WHO ICOPE (Integrated Care for Older People) Program in Preventing Age-related Functional Decline (ICOPE Trial.Fr)
The World Health Organization (WHO) has designed an integrated care program (ICOPE) aimed at maintaining the functions of elderly people to preserve their autonomy.
- Trial name
- ICOPE Fr (NCT06676839)
- Testing
- the complete ICOPE program
- Where
- 6 sites in France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Toulouse
HIV
Feasibility of an Exercise Intervention
The overall purpose of this research is to evaluate the effect of a home-based exercise program on physical function and to improve the health and quality of life for the HIV-infected older adult community.
- Trial name
- MESH (NCT01984060)
- Testing
- HOME-EX
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of Rochester
Cognitive Decline, Cognitive Impairment
Effects of Cognitive Intervention on Cognition, Mobility and Brain Electrocortical Activity
Within this project the investigators tested the effectiveness of 2-month of computerized cognitive training (CCT) on CogniFit online platform on 77 older adults, which were randomly divided into intervention and control group.
- Conditions
- Cognitive Decline, Cognitive Impairment, Aging, Motor Coordination or Function
- Trial name
- GIBKOP (NCT03860441)
- Testing
- Computerized cognitive training
- Where
- Slovenia
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Science and Research Centre Koper