Clinical trials: Functional Aging
Aging and Cognitive Health, Healty
PotenziaMente: A Digital Executive Function Training Intervention for Healthy Aging in the Elderly Population
The study, entitled "PotenziaMente: Cognitive Training in Aging," is a clinical trial designed to evaluate the effectiveness of an individualized tablet-based cognitive training program targeting executive functions (e.g.…
- Trial name
- NCT07639203
- Testing
- Remote Cognitive Training, Supervised In-Person Cognitive Training
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Trento
Brain Health, Longevity
L-serine and Strength Training in the Elderly
This study investigates whether taking the amino acid L-serine, either alone or in combination with targeted strength training, can have a positive effect on mental performance, brain function, and physical fitness in older…
- Conditions
- Brain Health, Longevity, Cognitive Performance, Strength Training Effects
- Trial name
- AAAging (NCT07466290)
- Testing
- Strength training, L-serine supplementation, Control (cornstarch)
- Where
- Austria
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Vienna
Cognitive Function, Exercise Training
Aerobic Exercise Effects on Cognitive Function in Aging Individuals
Positive effects are exerted by participating in moderate exercise training with physical activity which positively affects body health, including cognitive abilities, among older adults.
- Trial name
- NCT06650345
- Testing
- supervised aerobic exercise
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Saud University
Aging
Effects of Exergames on Muscle and Lung Function in Elderly
The goal of this study is to examine the effects of 8-weeks exergames program on pulmonary function, muscle strength and cognitive function in elderly.
- Trial name
- NCT06921057
- Testing
- exergame
- Where
- Taiwan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Chang Gung University
Hypertension, Physical Disability
The Effect of Sodium Reduction on Blood Pressure and Physical Function in Older Adults
This study will examine the effects of low sodium meal plan on seated blood pressure in older adults from a community-based, congregate senior living facility.
- Conditions
- Hypertension, Physical Disability, Aging
- Trial name
- SOTRUE (NCT04074941)
- Testing
- Dietary intervention
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hebrew SeniorLife
Healthy Ageing
Neuroplasticity: The Effects of Exercise Training on Cognitive and Affective Functioning of Older People
This study investigates the effects of exercise on older people's cognitive and affective functions, and the possible underlying neurobiological pathways.
- Trial name
- NCT04641429
- Testing
- Qigong exercise, Stretching exercise
- Where
- Hong Kong
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Sleep, Anxiety
Xbox Kinect, Sleep Quality, Anxiety and Functional Capacity in Older Adults
The present study aims to examine the effects of Xbox Kinect exercise training program on the sleep quality, anxiety and functional capacity in older adults. Older adults were randomized into two groups.
- Conditions
- Sleep, Anxiety, Aging, Exercise
- Trial name
- NCT04692272
- Testing
- Exercise in the XBOX kinect
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Physical Frailty
Protein and Exercise to Counteract Frailty in Older Adults
The purpose of this study is to determine the effects of interventions with high-protein diet alone or in combination with resistance training on muscle mechanical function (muscle power and strength), frailty status, functional…
- Trial name
- NCT03842579
- Testing
- Resistance training, High-protein diet, Recommendations
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- University of Southern Denmark
Aging, Adults With Overweight and Obesity
Effects of Physical Exercise and a Nutritional Supplement on Body Composition, Metabolic Function, and Overall Health in Adults With a Metabolically Challenging Profile
Early-onset metabolic disturbances (such as mild hyperglycemia, subclinical dyslipidemia, excess body fat, and reduced functional capacity) represent one of the major public health challenges among middle-aged and older adults.
- Conditions
- Aging, Adults With Overweight and Obesity, Supplementation, Exercise
- Trial name
- NCT07504068
- Testing
- Group 1: Exercise + thermogenic supplement (EX-TS)
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- University of Valencia
Erectile Dysfunction, Cardiac Disease
Stem Cells for the Improvement of Erectile and Cardiac Function in Aging Men
Men who present with erectile dysfunction as defined as an IIEF (International Index of Erectile Function) score less than 21 will be evaluated for risk factors for cardiovascular disease (CVD). This is a single-blind study.
- Trial name
- NCT02107118
- Testing
- ARM 1: AdMSC: adipose stem cells
- Where
- United States
- Sponsor
- Baylor College of Medicine
Obesity, Weight Loss
Utilizing Protein During Weight Loss to Impact Physical Function and Bone
This study is an ancillary study to the Utilizing Protein During Weight Loss to Impact Physical Function (UPLIFT) trial (NCT03074643) to evaluate the effects of diet composition (i.e., amount of protein and carbohydrate) during a…
- Conditions
- Obesity, Weight Loss, Diet Modification, Aging
- Trial name
- UPLIFT-Bone (NCT03819478)
- Testing
- Weight loss intervention months 0-6, Exercise intervention months 0-6, NutraBio™ CarboMax Supplement
- Where
- United States
- Volunteers
- 187 people
- Sponsor
- Wake Forest University Health Sciences
Ageing, Frailty
Physiotherapy Interventions on Functional Capacity, Balance and Mental Domains in Community-Dwelling Older Adults: A Randomized Clinical Trial With Two Parallel Groups
This study will investigate whether two different physiotherapy exercise programs can improve physical function, balance and mental well-being in older adults living in the community in Angola.
- Conditions
- Ageing, Frailty, Sarcopenia, Decline, Cognitive
- Trial name
- NCT07424274
- Testing
- Multicomponent Physiotherapy Exercise Program, Reduced Functional Physiotherapy Exercise Program
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Aveiro University
Cognitive Change, Cytokine Levels
The Effect of Oral Use of Lyophilised Royal Jelly on Cognitive Functions and Immune System in Elderly Individuals
Dementia is a significant public health problem, affecting 47 million people worldwide in 2015, according to World Health Organization data. It is expected to increase to 75 million in 2030 and reach 132 million in 2050.
- Conditions
- Cognitive Change, Cytokine Levels, Neuroinflammation
- Trial name
- NCT06404203
- Testing
- Balparmak Apitera Royal Jelly Herbal Capsule Food Supplement 500 mg/day, Balparmak Apitera Royal Jelly Herbal Capsule Food Supplement 1000 mg/day, Balparmak Apitera Royal Jelly Herbal Capsule Food Supplement 1500 mg/day
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medipol University
Aging
Feasibility Study of Post-hospitalization Interventions to Improve Physical Function in Older Adults
The purpose of this study is to test the feasibility of interventions to accelerate recovery of muscle mass and function in older adults following acute hospitalization.
- Trial name
- PACE (NCT02203656)
- Testing
- Nutritional Supplement, In-home exercise, Testosterone
- Where
- 2 sites in United States
- Volunteers
- 113 people
- Sponsor
- The University of Texas Medical Branch, Galveston
HIV, COPD
Translation Evaluation of Aging, Inflammation and HIV in Lung Function (TEAL)
Hypothesis;Aging modifies the risk of pulmonary dysfunction in HIV+ individuals. The study is a multicenter, prospective observational study of aging and pulmonary function in HIV.
- Conditions
- HIV, COPD, Pulmonary Disease, Aging
- Trial name
- TEAL (NCT02154880)
- Testing
- PFT, lab work, 6MWT
- Where
- United States
- Volunteers
- 323 people
- Sponsor
- University of Pittsburgh
Aging
Phosphatidylserine Improves Cognitive Function in the Elderly
Cognitive decline is a common symptom of aging, and age-related cognitive impairments are considered normal or inevitable, especially in people over 60, whose memory is more likely to be affected by age.
- Trial name
- PICFITE (NCT04920305)
- Testing
- Phosphatidylserine, Bean powder
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Older Adults, Physical Function
Curcumin and Function in Older Adults
This placebo-controlled RCT tests whether dietary supplementation with curcumin maintains or improves cognitive and physical function in older adults who are at high risk of functional decline due existing (mild) functional…
- Conditions
- Older Adults, Physical Function, Cognitive Function
- Trial name
- SPICE (NCT03085680)
- Testing
- Curcumin, microcrystalline cellulose
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Florida
Aging, Frailty
Mitophagy and Autophagy in Elderly Subjects
In recent years, evidence has shown that mitochondrial dysfunction plays an important role in the development of age-related muscle decline that may lead to frailty.
- Conditions
- Aging, Frailty, Mitophagy
- Trial name
- NCT02472340
- Testing
- Muscle Biopsy
- Where
- Netherlands
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Frailty Syndrome, Cognitive Impairment
Successful Aging and Frailty
Frailty is the term commonly utilized to describe the geriatric syndrome that exposes the elderly to increased risk of negative health-related events.
- Conditions
- Frailty Syndrome, Cognitive Impairment, Sarcopenia
- Trial name
- SAFe (NCT03963050)
- Testing
- Exercise Training, Exercise Training + Cognitive Training, Control
- Where
- Italy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Functional Aging, Subjective Cognitive Concerns
A Multidimensional Behavioral Intervention for Those at Risk for Alzheimer's Dementia
This intervention is designed to promote enhanced use of compensation strategies including calendar and task list use, and organization systems, as well as increased engagement with brain health activities including physical…
- Conditions
- Functional Aging, Subjective Cognitive Concerns, Compensation Strategies, Brain Health Activities
- Trial name
- NCT03549078
- Testing
- Intervention
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of California, Davis