Clinical trials: Functional Aging
Healthy Aging
Neuroathletic Exercise In The Elderly
Objective: The aim of this protocol study was to investigate the effect of neuroathletic exercise on walking speed, fall risk and cognitive function in the elderly.
- Trial name
- NCT07070336
- Testing
- Neuroathletic exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Strength Aerobic Training Elderly Lymphoma Sarcopenia Aging
Strength and Aerobic Training in Elderly Lymphoma Patients During Chemotherapy and Its Impact on Treatment Outcomes, Patients Functioning and Biological Markers of Aging
Frailty, one of geriatric syndromes, is considered a major obstacle for recovery from physiological stress. Such stress is imposed on patients with cancer by virtue of the disease itself but even more so by the treatment.
- Trial name
- NCT03100175
- Testing
- physiotherapy
- Volunteers
- 100 people
- Sponsor
- Rabin Medical Center
Ageing
Generation 100: Blood Volume and Cardiac Function in Healthy Aging
Hypothesis: Exercise will reduce morbidity and mortality rates in an elderly population. The extent of reduction will be intensity dependent.
- Trial name
- NCT01765816
- Testing
- high intensity interval training, moderate intensity training
- Where
- Norway
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Postmenopausal, Female
How Seasons Affect Kidney Health in Post-Menopausal Females
The investigators are assessing how seasonal changes affect kidney function biomarkers in post-menopausal women, an understudied group.
- Trial name
- NCT06866743
- Testing
- There will be no intervention.
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Florida State University
Aging
Acute Passive Heating in Healthy Older Adults
Aging is associated with a decline in cardiovascular health, cognitive function and losses in muscle strength, with half or more of those over age 65 suffering from two or more comorbidities (e.g., heart disease, type 2…
- Trial name
- NCT05622747
- Testing
- Passive heating
- Where
- United Kingdom
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Portsmouth
Aging, Healthy
ACTIVE: Advanced Cognitive Training for Independent and Vital Elderly
The purpose of the ACTIVE study was to test if cognitive training interventions could maintain functional independence in elders by improving basic mental abilities, with follow-up assessments through five years.
- Trial name
- ACTIVE (NCT00298558)
- Testing
- Cognitive Training
- Where
- 7 sites in United States
- Volunteers
- 2,832 people, healthy volunteers welcome
- Sponsor
- Carelon Research
Lifestyle, Healthy, Muscle Weakness
RE-inventing Strategies for Healthy Ageing; Recommendations and Tools
The goal of the RESTART RCT is to examine whether a complex lifestyle intervention, coordinated with municipal and non-government organizations (NGO), can establish and preserve improvements in risk factors and functional…
- Conditions
- Lifestyle, Healthy, Muscle Weakness, Abdominal Obesity, Cardiometabolic Syndrome
- Trial name
- RESTART (NCT06122441)
- Testing
- Complex lifestyle intervention, Physical activity monitoring and recommendations
- Where
- Norway
- Volunteers
- 119 people
- Sponsor
- University of Tromso
Aging
Westlake Nutrition and Brain Health Study
The Westlake Nutrition and Brain Study (WEBRAIN), a sub-study of the Guangzhou Nutrition and Health Study, is a prospective cohort study of residents in Guangzhou city.
- Trial name
- WEBRAIN (NCT04135066)
- Testing
- Refine grain breakfast, Whole grain breakfast, Oral Glucose Tolerance test (75g 2-hour)
- Where
- China
- Volunteers
- 1,425 people, healthy volunteers welcome
- Sponsor
- Westlake University
Aging, Oxidative Stress
Whole Body Vibrations on Functional Capacity, Muscular Strength, and Biochemical Profile in Elders
This study is a randomized clinical trial that has as objective to evaluate the effects of training with a vibratory platform on body composition, muscular strength functional capacity, flexibility and biochemical profile on…
- Trial name
- NCT03030456
- Testing
- Power Plate®
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Santa Cruz do Sul
Aging
Functional Mobility in the Elderly: Influence of Morphological, Neuromuscular and Training Parameters
Life expectancy and elderly population are increasing. Health professionals try to provide longevity with good quality of life for this population, through the functional independence maintenance.
- Trial name
- NCT03206580
- Testing
- Concentric training, Concentric-Eccentric training
- Where
- Brazil
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Obesity
Vibegron for ENergy Thinking and Resilience in Aging
This 12-week randomized, double-blind, placebo-controlled trial will test the hypothesis that Vibegron (brand name GEMTESA) can improve energy metabolism, cardiometabolic risk factors, and physical and cognitive function in…
- Trial name
- VENTURA (NCT06987383)
- Testing
- Vibegron
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Wake Forest University Health Sciences
Aging
Role of Flavanols In Cardiovascular Function in Healthy Aging
Groups of naturally occurring compounds called flavonoids are found in foods such as fruits and vegetables, red wine, tea, dark chocolate and cocoa products.
- Trial name
- NCT01395277
- Testing
- High Flavanol first then Low Flavanol, Low Flavanol first then High Flavanol
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Exercise Training, Executive Function
Multi-Domain Exercise and Memory in Adults Relative to ApoE Genotype: A fMRI Study
The current project utilizes a single-blinded, double arm, 6-month randomized controlled trial to assess the effects of a multi-domain exercise program on memory performance, as well as cortical activities during the memory tasks…
- Conditions
- Exercise Training, Executive Function, Aging
- Trial name
- NCT05068271
- Testing
- Multi-Domain Exercise Program, Control Group
- Where
- 2 sites in Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Fall, Healthy Aging
Validity and Reliability of a Depth Camera-based Automated Physical Function and Fall Risk Assessments
Falls significantly reduce physical function as well as quality of life which leads to failure of successful aging among elders.
- Trial name
- NCT06519864
- Testing
- Azure Kinect-based Tandem Stance Test (ATST) and Physical Therapist's Measurements of Tandem Stance Test (PTST), Azure Kinect-based Five Times Sit-to-Stand Test (AFTSS) and Physical Therapist's Measurements of Five Times Sit-to-Stand Test (PFTSS), Azure Kinect-based Timed Up and Go Test (ATUG) and Physical Therapist's Measurements of Timed Up and Go Test (PTUG)
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sahmyook University
Frailty, Aging
Community-Based Multicomponent Exercise and Recreational Programme for Older Adults
This quasi-experimental, non-randomized controlled evaluation examined whether participation in ELDERPLAY, a community-based programme combining Vivifrail-based multicomponent exercise with adapted traditional games, was…
- Conditions
- Frailty, Aging, Physical Functional Performance, Postural Balance
- Trial name
- ELDERPLAY (NCT07864831)
- Testing
- ELDERPLAY multicomponent exercise and recreational programme
- Where
- Spain
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Brain Aging
AvoCog - the Effect of Daily Avocado Intake on Cognitive Function in Older Adults
The goal of this clinical trial is to determine if adding avocados to the diet of impacts cognition in 70 older adults, age 65-85, without dementia.
- Trial name
- AvoCog (NCT06137339)
- Testing
- Avocado Group
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Physical Activity
Supervised Group-based Walking Intervention Among Inactive Older Adults in Saudi Arabia
The purpose of the proposed study is to compare the effects of supervised group-based walking and non-supervised individual-based walking interventions on frailty, cognitive function and quality of life among inactive older…
- Trial name
- NCT05151575
- Testing
- supervised group-based walking and non-supervised individual-based walking interventions
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
Physical Activity, Physical Function
Structured Self-Talk and Wearable-Assisted Walking for Physical Activity and Function in Older Adults
The goal of this randomized clinical trial was to examine whether adding structured self-talk to wearable-assisted walking could support physical activity and physical function in community-dwelling older adults.
- Conditions
- Physical Activity, Physical Function, Healthy Aging
- Trial name
- NCT07767136
- Testing
- Moderate-Intensity Walking Program, Wearable Activity Device, Structured Self-Talk Training
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- CHENG-EN WU
Aging, Frailty
Evaluation of a Health Monitoring Platform for Elderly in Home Care Context
This study aims at, as a primary objective, studying acceptability of elderly about a health monitoring platform for home support and home care.
- Trial name
- ACCORDS (NCT04514536)
- Testing
- Health monitors
- Where
- France
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Aging
Yoga and Diet on Cognitive, Nutritional Status, Mental and Functional Abilities in Older Adults
Yoga has emerged as a powerful therapeutic practice for enhancing physical and mental health across all age groups, including older adults and younger individuals.
- Trial name
- NCT06304688
- Testing
- Yoga and Mediterranean Diet intervention
- Where
- Spain
- Volunteers
- 125 people
- Sponsor
- University of Jaén