Clinical trials: Functional Bowel Disorder, open to volunteers
Anal Cancer
ANCA II - Quality of Life and Functional Outcome in Patients With Anal Cancer
Anal cancer is a rare disease, but the incidence is rising. About 200 patients will get this type of cancer yearly in Sweden. Curative treatment includes chemotherapy and radiotherapy.
- Trial name
- ANCAII (NCT04792892)
- Testing
- Questionnaires
- Where
- Sweden
- Volunteers
- 600 people
- Sponsor
- Sahlgrenska University Hospital
IBS (Irritable Bowel Syndrome), Diarrhea
Use of A Complex Gut Bacterial Consortium (MITI 001) for the Treatment of Irritable Bowel Syndrome With Diarrhea
While the pathophysiology of diarrhea-predominant irritable bowel syndrome (IBS-D) is complex and heterogeneous, dysbiosis of the gut microbiome is frequently observed, suggesting that a substantial subset of patients with…
- Trial name
- CURE-IBS-D (NCT07238790)
- Testing
- MITI-001 administration
- Where
- 2 sites in United States
- Volunteers
- 13 people
- Sponsor
- Stanford University
Irritable Bowel Syndrome
Efficacy of Glutamine Supplementation in Patients Suffering From Irritable Bowel Syndrome With Impaired Intestinal Permeability
Irritable bowel syndrome (IBS) affects approximately 5% of the general population and remains a daily problem in the practice of clinicians with inconsistent effectiveness of treatments while patients' expectations are high.
- Trial name
- MISSISIIPI (NCT06291038)
- Testing
- • Experimental group: treatment with glutamine at a dose of 5g 3 times a day for 8 weeks, • Control group: treatment with a protein powder (Protifar) (Placébo) 5g 3 times a day for 8 weeks.
- Where
- 4 sites in France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Rouen
Functional Gastrointestinal Disorders, Gastroesophageal Reflux
Prevalence and Natural History of Functional Gastrointestinal Disorders Among At-risk Infants.
The goal of this observational study is to learn about the prevalence and characteristics of functional gastrointestinal disorders (FGID) in at risk infants (former preterm infants and those with birth asphyxia) during the first…
- Conditions
- Functional Gastrointestinal Disorders, Gastroesophageal Reflux, Constipation - Functional, Diarrhea
- Trial name
- FUSID (NCT06031025)
- Testing
- Questionnaire, clinical examination
- Where
- Italy
- Volunteers
- 71 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Alcoholic Liver Disease
French National MICMAF Cohort
Excessive alcohol consumption is a major public health problem, particularly in France. It is the leading cause of cirrhosis and hepatocellular carcinoma.
- Trial name
- MICMAF (NCT05895890)
- Testing
- Sequential sampling (stool, saliva, serum) .
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Mullerian Anomaly of Uterus, Nec, Mullerian Anomaly of Vagina
Diagnostic, Therapeutic and Reproductive Aspects of Patients With Mullerian Anomalies
The purpose of this study is to get a better understanding of the clinical implications (including reproductive problems and obstetric complications), appropriate diagnostic tools and correct surgical treatment of Mullerian…
- Conditions
- Mullerian Anomaly of Uterus, Nec, Mullerian Anomaly of Vagina, Mullerian Anomaly of Cervix
- Trial name
- MULAN (NCT04627818)
- Where
- Belgium
- Volunteers
- 1,500 people
- Sponsor
- University Hospital, Ghent
IBS (Irritable Bowel Syndrome)
High-Resolution Measurements of Diet-Microbiome Interactions
The goal of this clinical trial is to characterize regional intestinal fermentation physiology and determine how the response to fermentable dietary fiber differs between healthy individuals and individuals with irritable bowel…
- Trial name
- NCT07856823
- Testing
- Inulin, Low-fiber control breakfast shake, Atmo Gas-Sensing Capsule
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Stanford University
CHAPLE Disease
A Study to Test the Safety of Pozelimab in Pediatric Participants 1 to 5 Years of Age With a Rare Disease Called CHAPLE (Complement Hyperactivation, Angiopathic Thrombosis, Protein-losing Enteropathy) Disease
This study is researching a drug called pozelimab (called "study drug"). The main aim of this study is to monitor the safety and tolerability of the study drug.
- Trial name
- NCT07142343
- Testing
- Pozelimab
- Where
- Turkey (Türkiye)
- Volunteers
- 5 people
- Sponsor
- Regeneron Pharmaceuticals
Colorectal Cancer, Older Adults (60 - 85 Years Old)
Chemo Brain Prehab Project
Colorectal cancer is 37% higher in the North West than the national average and is treated by chemotherapy, including fluorouracil, capecitabine, and oxaliplatin.
- Conditions
- Colorectal Cancer, Older Adults (60 - 85 Years Old), Physically Inactive, Chemotherapy
- Trial name
- CHEMOBRAIN (NCT07341217)
- Testing
- Exercise Prehabilitation, Multivitamins, Standard Care (in control arm)
- Where
- 4 sites in United Kingdom
- Volunteers
- 86 people
- Sponsor
- Dr. Chris Gaffney
Irritable Bowel Syndrome (IBS)
Personalized Probiotic Treatments for Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is characterized by stomach pain and altered bowel habits. It affects about 5 million people in Canada. Doctors don't fully understand what causes IBS, so treatments often don't work well.
- Trial name
- NCT07872514
- Testing
- Probiotic containing B longum, Probiotic Lactobacillus
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- McMaster University
Bowel Sounds, Colorectal Cancer
The Value of Bowel Sounds in Evaluating Postoperative Intestinal Function Recovery in Colorectal Cancer Patients
This study enrolls patients scheduled to undergo curative surgery for colorectal cancer. Bowel sounds will be assessed preoperatively and postoperatively.
- Conditions
- Bowel Sounds, Colorectal Cancer, Intestinal Obstruction, Postoperative Ileus
- Trial name
- BRIEF (NCT07705139)
- Testing
- colorectal surgery
- Where
- China
- Volunteers
- 172 people
- Sponsor
- Zhongnan Hospital
IBS (Irritable Bowel Syndrome)
Transcranial Magnetic Stimulation and Pharmacologic/Probiotic Interventions for Diarrhea-Predominant IBS
What is the study about? This study is for adults with diarrhea-predominant irritable bowel syndrome (IBS-D) who suffer from chronic visceral pain.
- Trial name
- rTMS (NCT07172139)
- Testing
- Active rTMS + Pinaverium Bromide, Active rTMS + Bifidobacterium
- Volunteers
- 140 people
- Sponsor
- Rui Li
Irritable Bowel Syndrome With Diarrhea
Effects of the Multispecies Probiotic Ecologic Barrier in IBS Patients With Upper GI Symptoms and Anxiety, Depression, or Stress
The aim of this clinical trial is to find out whether Ecologic Barrier is effective in supporting the treatment of irritable bowel syndrome (IBS) in adults.
- Trial name
- NCT07656623
- Testing
- Ecologic Barrier
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- Institute of Gastroenterology and Hepatology, Vietnam
Irritable Bowel Syndrome
Calisthenics Versus Cycling Exercises on Interleukin-6 and Quality of Life in Benha University Students With Irritable Bowel Syndrome
this study will be conducted to compare between the effect of calisthenics versus cycling exercises on interleukin-6 and quality of life in Benha University students with irritable bowel syndrome.
- Trial name
- IBS (NCT07760298)
- Testing
- Calisthenics exercises, Cycling Exercises, diet advices
- Volunteers
- 60 people
- Sponsor
- Cairo University
Irritable Bowel Syndrome
Fecal Microbiota Transplantation to Relieve Symptoms of Irritable Bowel Syndrome With Constipation
Irritable bowel syndrome (IBS) is a complex multifactorial functional disorder, whose pathophysiology is largely associated to an impairment of the intestinal microbiota composition, namely dysbiosis.
- Trial name
- TRAMIR-S (NCT05803993)
- Testing
- Fecal microbiota transplantation (FMT) Single FMT infusion
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Pelvic Organ Prolapse, Rectocele
Multicenter Ventral Mesh Rectopexy Registry Collaborative
The goal of this multicenter observational study is to collect data prospectively of patients with pelvic organ prolapse undergoing ventral mesh rectopexy (as well as rectoceles, entero-/sigmoidoceles/ intussusception/ rectal…
- Conditions
- Pelvic Organ Prolapse, Rectocele, Enterocele, Rectal Prolapse
- Trial name
- M2R2 (NCT05918367)
- Where
- 5 sites in Belgium
- Volunteers
- 200 people
- Sponsor
- University Hospital, Antwerp
Irritable Bowel Syndrome, Irritable Bowel Syndrome - Constipation
Efficacy of Chatbot for Irritable Bowel Syndrome (IBS) Patients
The goal of this clinical trial is to evaluate the efficacy of an automated chatbot system in improving quality of life, reducing depression and anxiety, and decreasing visceral sensitivity in patients with Irritable Bowel…
- Conditions
- Irritable Bowel Syndrome, Irritable Bowel Syndrome - Constipation, Irritable Bowel Syndrome - Diarrhoea, Irritable Bowel Syndrome - Mixed
- Trial name
- IrBiS (NCT06837064)
- Testing
- Chatbot supporting system
- Where
- Russia
- Volunteers
- 54 people
- Sponsor
- Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department
COVID-19-Associated Encephalitis, Long COVID
Longterm Influence of Pediatric Long COVID Syndrome
We enroll pediatric patients who were diagnosed COVID-19 for main observation target. We will perform brain MRI and neuropsychiatric evaluation 4-6 months after COVID-19 diagnosed.
- Trial name
- NCT05566392
- Testing
- Brain MRI
- Where
- Taiwan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Tricuspid Regurgitation (TR)
Impact of Severe Tricuspid Regurgitation Correction on Gut Microbiota and Gastrointestinal Function
Tricuspid regurgitation (TR) is gaining increasing attention within the cardiological community due to its poor prognosis, challenging clinical presentation and difficult treatment.
- Trial name
- Tri-GuM (NCT06902922)
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Francesco Maisano
IBS (Irritable Bowel Syndrome), Bloating
A Study Evaluating the Impact of Regular FODMAP-targeting Digestive Enzyme Blend Use on Gastrointestinal Symptoms in Individuals With Self-Reported Bloating
This study is a randomized, double-blind, placebo-controlled, within-individual crossover trial designed to assess the impact of regular use of a consumer-grade FODMAP-targeting digestive enzyme blend (FODZYME®) on…
- Conditions
- IBS (Irritable Bowel Syndrome), Bloating, Abdominal Pain, Gut Health
- Trial name
- NCT07591584
- Testing
- FODMAP-targeting digestive enzyme blend
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Kiwi Health Inc