Clinical trials: Functional Capacity, open to volunteers
Chronic Obstructive Pulmonary Disease
Oral Sildenafil for Exercise Capacity, Dyspnea and Cardiopulmonary Function in COPD
Chronic obstructive pulmonary disease (COPD) is a condition characterized by airway obstruction. Patients with COPD experience significant shortness of breath on exertion.
- Trial name
- NCT05061368
- Testing
- Sildenafil Citrate
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Stroke
Effects of Inspiratory Muscle Training on Stroke Rehabilitation Outcomes
This study is designed to explore the effects of a 4-week protocol of inspiratory muscle training (IMT) at 50% maximum inspiratory pressure (MIP) on respiratory function, diaphragm thickness, balance control, exercise capacity…
- Trial name
- NCT06640101
- Testing
- IMT-stable group (sitting on a stable surface), IMT-unstable group (sitting on an unstable surface), Conventional treatment
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Hong Kong Metropolitan University
Diabetes, Elderly
Manual Diaphragmatic Release on Ventilatory Functions in Elderly Diabetic Women
Evaluate the effect of manual diaphragmatic release on ventilatory functions and functional capacity in elderly diabetic women.
- Trial name
- NCT06724744
- Testing
- Aerobic training, Manual Diaphragm Release
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Pelvic Floor Dysfunction, Defecation Disorders
The Relationship Between Pelvic Floor Dysfunction and Quality of Life, Functional Capacity, Gait Parameters, and Static Balance in Children With Defecation Disorders
Defecation disorders are common in children and may adversely affect pelvic floor function, gait, balance, functional capacity, and health-related quality of life.
- Trial name
- NCT07727837
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Izmir Bakircay University
Functional Capacity
6-Minute Walk Test Assessment Via Mobile App
This study aims to develop an Android-based 6-Minute Walk Test (6MWT) application to facilitate quick and efficient functional capacity assessment in clinical settings.
- Trial name
- NCT06839521
- Testing
- Walk Test-T, Walk Test-A
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Prehabilitation, Functional Capacity
Prehabilitation to Enhance Preoperative Function in Elderly Undergoing Abdominal Malignancy Surgery
The goal of this observational study is to evaluate the effectiveness of the multimodal prehabilitation program at the Siriraj Integrated Preoperative and Prehabilitation Center (SiPAP) on improving preoperative walking capacity…
- Trial name
- NCT07456943
- Volunteers
- 110 people
- Sponsor
- Siriraj Hospital
Percutaneous Coronary Intervention
Effects of Diaphragmatic and Abdominal Neuromuscular Electrical Stimulation in Post-PCI Patients
This study is a randomized controlled trial designed to evaluate the effects of combined diaphragmatic and abdominal neuromuscular electrical stimulation (NMES) on arterial blood gases, pulmonary function, left ventricular…
- Trial name
- NCT07629037
- Testing
- Neuromuscular Electrical Stimulation (NMES), Standard Cardiac Rehabilitation
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Congenital Heart Diseases, Resistance Training
Hospital-Based and Home-Based Resistance Training in Adult Congenital Heart Disease
Congenital heart disease (CHD) is defined as functional or anatomical abnormalities of the heart and major intrathoracic vessels present at birth.
- Conditions
- Congenital Heart Diseases, Resistance Training, Muscle Strength, Functional Capacity
- Trial name
- NCT06680973
- Testing
- Hospital-Based Resistance Training, Home-Based Resistance Training
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Hacettepe University
Hypertension, Aging
Effect of Heated Water-Based Versus Land-Based Exercise Training on Hemodynamic Variables, Functional Capacity and Quality of Life in Older Hypertensive
BACKGROUND: Physical exercise promotion is one of the main global goals of innumerous health and medical societies for preventing and managing noncommunicable chronic diseases (NCDs), being one of the main therapeutic for the…
- Conditions
- Hypertension, Aging, Exercise
- Trial name
- HExOLD (NCT07131748)
- Testing
- Physical Exercise Session in heated Swimming Pool - HEx, Physical Exercise Session in Land- LEx, Control Session Without Exercise- CON
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Sarcopenia, Liver Cirrhosis
ELECTRICAL STIMULATION AND EXERCISE FOR MUSCLE LOSS IN CIRRHOSIS PATIENTS
Introduction: Sarcopenia, whether primary or secondary, substantially impacts the quality of life of patients post-hospital discharge. Compromised functional capacity can lead to a high prevalence of readmissions.
- Trial name
- E-SEEM (NCT07162636)
- Testing
- NMES+, NMES -
- Volunteers
- 112 people
- Sponsor
- Hospital Universitário Professor Edgard Santos
Huntington Disease, Sarcopenia
Creatine and Beta-Hydroxy-Beta-Methylbutyrate (HMB) Supplementation Plus Home-Based Exercise for Sarcopenia in Huntington's Disease
Huntington's disease (HD) is a rare neurodegenerative disorder in which accelerated loss of muscle mass, strength and autonomy (physical frailty and sarcopenia) contributes to functional decline.
- Conditions
- Huntington Disease, Sarcopenia, Frailty
- Trial name
- SARCO-HD (NCT07902206)
- Testing
- Creatine monohydrate, Beta-hydroxy-beta-methylbutyrate (HMB), Home-based multicomponent exercise program
- Where
- Spain
- Volunteers
- 88 people
- Sponsor
- Universidad de Burgos
Sternotomy, Functional Capacity
Impact of Pre- and Early Post-operative Isometric Handgrip Training on Functional Capacity and Autonomic Function After Sternotomy
This study aims to evaluate the effect of isometric handgrip (IHG) training on functional capacity and autonomic function before and after sternotomy.
- Conditions
- Sternotomy, Functional Capacity, Autonomic Function
- Trial name
- NCT07906873
- Testing
- Isometric Handgrip Training using analog hand dynamometer, Standard care including breathing and motor exercises
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Chronic Kidney Disease (CKD), Stages 3-4 Exercise Tolerance / Functional Capacity Vascular Health / Arterial Stiffness Fatigue in CKD
"Hypoxic vs. Aerobic Training in Chronic Kidney Disease
Chronic kidney disease (CKD) leads to poor exercise tolerance, vascular dysfunction, and reduced quality of life. This randomized controlled trial will compare intermittent hypoxic training (IHT) with traditional aerobic training…
- Trial name
- IHT-CKD (NCT07180875)
- Testing
- hypoventilation group
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pharos University in Alexandria
Lupus Erythematosus, Systemic
Effects of High-intensity Interval Training in Patients With Systemic Lupus Erythematosus
The aim of this study is to evaluate the safety and effects of high-intensity interval training (HIIT) combined with resistance training in patients with systemic lupus erythematosus
- Trial name
- SLE-HIIT (NCT06166199)
- Testing
- HIIT combined with resistance training
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Geriatric, Aerobic Exercise
Comparing Music-Supported and Traditional Aerobic Training in Geriatric Health Outcomes
The aim of this study is to comparatively evaluate the effects of a music therapy-based aerobic exercise program and traditional aerobic exercise training on cardiopulmonary functions, functional capacity, balance, peripheral…
- Conditions
- Geriatric, Aerobic Exercise, Music Therapy, Physiotherapy and Rehabilitation
- Trial name
- NCT06980311
- Testing
- Aerobic Exercise, Aerobic exercise with music therapy
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Heart Failure With Preserved Ejection Fraction
EXercise and Activin Inhibition to Modulate InflammatioN Effects on Heart Failure and Cognition (EXAMINE-HFC)
The goal of this clinical trial is to learn if therapy with activin ligand-trap biological therapy (an investigational drug) combined with exercise training can improve exercise capacity and cognitive function in heart failure…
- Trial name
- EXAMINE-HFC (NCT07202000)
- Testing
- Activin ligand-trap biological therapy
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Massachusetts General Hospital
Incentive Spirometer, Pulmonary Function
Effect of Incentive Respiratory Training on Pulmonary Functions and Functional Capacity in Children With B-thalassemia Major
The study was done to: 1. Investigate the effect of respiratory training on functional lung capacity and 2. To detect the effect of respiratory training on pulmonary functions in children with β-thalassemia major. 3.
- Conditions
- Incentive Spirometer, Pulmonary Function, Functional Capacity, Child, Only
- Trial name
- NCT07112703
- Testing
- Incentive spirometer exercises, Diaphragmatic breathing, Pursed lip breathing:
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Rawan Mohammed Khairy Mostafa Elsawy
Ovarian Cancer, Ovarian Cancer Stage III
Prehabilitation in Gynaecological Cancer Patients
Prehabilitation refers to interventions aiming to improve patients' resilience and functional capacity before a known stressful event, e.g., scheduled surgery.
- Conditions
- Ovarian Cancer, Ovarian Cancer Stage III, Ovarian Cancer Stage IV, Endometrial Cancer
- Trial name
- PHOCUS (NCT04789694)
- Testing
- Physiological intervention, Psychological intervention, Nutritional intervention
- Where
- Czechia
- Volunteers
- 64 people
- Sponsor
- Charles University, Czech Republic
Pulmonary Disease, Chronic Obstructive (COPD)
Additional Effects of Box Breathing Technique With Short Term Pulmonary Rehabilitation on Dyspnea and Functional Capacity in Patients With Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease is progressive and irreversible respiratory condition characterized by persistent airflow limitation leading to dyspnea and reduced functional capacity.
- Trial name
- NCT07518472
- Testing
- Short term Pulmonary Rehabilitation, Box breathing with short term pulmonary rehabilitation
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Foundation University Islamabad
Investigating the Effects of Power Training in the Elderly
Effects of Different Power Training Intensities in Older Adults
Power (strength × velocity) is a crucial component for maintaining independence during aging. Therefore, investigating interventions aimed at improving this physical capacity is essential for this population.
- Trial name
- NCT07023146
- Testing
- Moderate to high intensity (PTMH; 65-80% of 1-repetition maximum [1RM]) ), low to moderate intensity (PTLM; 40-60% of 1-repetition maximum [1RM])
- Where
- Brazil
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul