Clinical trials: Functional Capacity, open to volunteers
Fibromyalgia
Respiratory Function in Fibromiyalgia Syndrome
Fibromyalgia is a condition that may lead to a decline in respiratory function, as well as impaired oxygen delivery to and utilization by the muscles-factors that contribute to fatigue and reduced exercise capacity.
- Trial name
- NCT07913126
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Conventional Radiofrequency Thermocoagulation Application to the Articular Branches of the Femoral and Obturator Nerve, Chronic Hip Pain
Long-Term Follow-up of Radiofrequency to Articular Branches of the Femoral and Obturator Nerve in Chronic Hip Pain
It has been observed that the deterioration in the physical performance of the hip, the medical need before the specialist consultation and the deterioration in the health status can progress treatment[3].
- Trial name
- NCT06751472
- Testing
- VPS (Verbal Pain Score), WOMAC (Western Ontario and McMaster Universities Arthritis Index) scale
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Aydin Adnan Menderes University
Cerebral Palsy
Augmenting Ankle Plantarflexor Function in Cerebral Palsy
The first specific aim is to quantify improvement in ankle muscle function and functional mobility following targeted ankle resistance gait training in ambulatory children with cerebral palsy (CP).
- Trial name
- NCT05154253
- Testing
- Biomotum Spark: Robotic ankle assistance, Biomotum Spark: Robotic ankle resistance, Standard gait training
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Northern Arizona University
Postpartum Physical Fitness and Functional Performance
Strong as a Mother
This study will evaluate Strong as a Mother, an existing community exercise program for women returning to exercise after childbirth.
- Trial name
- NCT07867275
- Testing
- Supervised Postpartum Functional Strength Training and Aerobic Conditioning
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Penn State University
Dilated Cardiomyopathy
Bromocriptine in Dilated Cardiomyopathy Among Women of Reproductive Age
Dilated cardiomyopathy (DCM) is a condition associated with left and /or right ventricular (LV) dilatation and systolic dysfunction without coronary artery disease or abnormal loading circumstances proportionate to the severity…
- Trial name
- NCT06250257
- Testing
- Bromocriptine mesylate plus standard GDMT
- Where
- Ethiopia
- Volunteers
- 112 people
- Sponsor
- Jimma University
Chronic Disease, Type 2 Diabetes Mellitus (T2DM), Obesity, Overweight
Truway Diagnostic Tools in Primary Care
This study evaluates the effectiveness of Truway Health-sourced portable diagnostic devices, including ultrasound and blood glucose monitors, in early detection of chronic conditions in outpatient primary care settings.
- Conditions
- Chronic Disease, Type 2 Diabetes Mellitus (T2DM), Obesity, Overweight, Hypertension, Cardiovascular Disease Acute
- Trial name
- TruDxPC (NCT07209527)
- Testing
- Truway Portable Ultrasound Device, Truway Blood Glucose Monitor, Standard Oral Hypoglycemic Agent
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Truway Health, Inc.
Cardiovascular Diseases, Cardiac Rehabilitation
Threshold-Based Versus Range-Based Exercise Intensity Prescription in Cardiac Rehabilitation
Cardiac rehabilitation is an important part of the treatment of patients with cardiovascular disease. Supervised aerobic exercise improves physical fitness, functional capacity, and quality of life.
- Trial name
- T-REXI-CR (NCT07908810)
- Testing
- Threshold-Based Aerobic Exercise Intensity Prescription, Range-Based Aerobic Exercise Intensity Prescription
- Where
- 9 sites in Belgium
- Volunteers
- 230 people
- Sponsor
- Hasselt University
Atrial Fibrillation (AF), Heart Failure (HF)
Effects of Enhanced External Counterpulsation Combined With Cardiac Rehabilitation in Patients With Atrial Fibrillation
This is a prospective randomized controlled trial designed to evaluate the effectiveness of enhanced external counterpulsation (EECP) combined with cardiac rehabilitation in patients with atrial fibrillation.
- Conditions
- Atrial Fibrillation (AF), Heart Failure (HF), Cardiac Rehabilitation
- Trial name
- EECP AF CR (NCT07058987)
- Testing
- Cardiac Rehabilitation Combined With EECP, Routine Medical Care
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Lanzhou University Second Hospital
Juvenile Idiopathic Arthritis (JIA)
Reliability and Validity of the Glittre Activities of Daily Living Test in Children and Adolescents With Juvenile Idiopathic Arthritis
Juvenile Idiopathic Arthritis (JIA) is children's most common inflammatory rheumatic disease. The International League of Associations for Rheumatology (ILAR) defines it as a chronic arthritis condition that begins before the age…
- Trial name
- NCT06806774
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Hacettepe University
Sleep Disturbance, Aging
Sleep Quality in Assisted-Living Residents
Assisted living residents who have sleep disturbances are at great risk of developing cognitive impairments. The identification of factors that increase sleep problems in this population is the first step towards improving sleep…
- Trial name
- NCT04400617
- Testing
- Cross-sectional assessments to examine the relationship among sleep quality, functional/physical capacity, and cognitive performance.
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- University of Calgary
Stress, Psychological Factors
Body Awareness Therapy in High Stressed Young Adults: Effects on Function, Balance, Sleep and Mood
Body Awareness Therapy (BAT) is a holistic approach to human movement that considers the physical, physiological, psychological, and existential aspects of human existence.
- Conditions
- Stress, Psychological Factors, Sleep, Postural Balance
- Trial name
- NCT07045792
- Testing
- Body Awareness Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Fragility
Effects of VIVIFRAIL Program on Functional Capacity and Geriatric Syndromes in the Elderly.
The aim of this quasi-experimental, pretest-posttest study is to evaluate the effectiveness of the Vivifrail multicomponent physical exercise program in improving the functional capacity of pre-frail and frail older adults (aged…
- Trial name
- VIVIAL (NCT07436715)
- Testing
- Behavioral: Vivifrail multicomponent physical exercise program
- Where
- Spain
- Volunteers
- 86 people
- Sponsor
- Elena Pérez Expósito, MD
HFrEF - Heart Failure With Reduced Ejection Fraction
Impact of Barostimulation on Hemodynamics in Adults With Heart Failure
This study evaluates the effects of the implantation and adjustment of the CVRx Barostim device in adult patients with heart failure with reduced ejection fraction who are receiving maximally tolerated doses of guideline directed…
- Trial name
- BREATHE-HF (NCT07335510)
- Testing
- Baroreflex Activation Therapy
- Where
- 7 sites in United States
- Volunteers
- 58 people
- Sponsor
- Columbia University
Aortic Stenosis Disease
Clinical and CPET Parameters That Predict Improvement in Functional Capacity After TAVI
Determining Clinical and Cardiopulmonary exercise testing Parameters that may predict Improvement in Capacity After Transcatheter Aortic Valve Implantation
- Trial name
- NCT06833762
- Where
- Spain
- Volunteers
- 161 people
- Sponsor
- Hospital Clinic of Barcelona
Pulmonary Hypertension Due to Lung Disease (Disorder)
Influence of Cardiopulmonary Rehabilitation on Cardiorespiratory Adaptation in Patients With Pulmonary Hypertension
This study aims to investigate the effect of cardiopulmonary rehabilitation on cardiorespiratory parameters and functional capacity in patients with pulmonary hypertension.
- Trial name
- NCT07648524
- Testing
- cardiopulmonary rehabilitation in the form of moderate-intensity interval aerobic training, Inspiratory Muscle Training, Medical treatment
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Cairo University
Heart Failure and Reduced Ejection Fraction, Obesity & Overweight
Evaluation of the Efficacy and Safety of Tirzepatide, a Dual GLP-1/GIP Agonist, on Functional Capacity in Reduced Ejection Fraction Heart Failure Patients With Obesity
The goal of this clinical trial is to learn if tirzepatide works to improve physical function in adults with heart failure and obesity. It will also learn about the safety of tirzepatide.
- Conditions
- Heart Failure and Reduced Ejection Fraction, Obesity & Overweight, Tirzepatide
- Trial name
- DUAL-HFrEF (NCT07738276)
- Testing
- Tirzepatide
- Volunteers
- 60 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Polyneuropathy, Charcot Marie Tooth Disease (CMT)
Effects of Resistance Exercises in Hereditary Sensory-Motor Neuropathy (Charcot-Marie-Tooth Disease)
The goal of this clinical trial is to compare the effects of an 8-week resistance exercise training program on skeletal muscle quality, functional capacity, and quality of life in young individuals aged 15 to 29 years, with and…
- Trial name
- PNP (NCT07152197)
- Testing
- Progressive Resistance Exercise Training
- Where
- 2 sites in Chile
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Universidad de La Frontera
Alzheimer's Dementia (AD), Alzheimer Disease (AD)
Exercise in Alzheimer's Disease: Functional Biomarkers
Alzheimer's disease (AD) is the leading cause of dementia worldwide and involves systemic alterations beyond the brain, such as loss of muscle strength, chronic low-grade inflammation, and gut microbiome dysbiosis.
- Trial name
- AD-GUT-EX (NCT07918417)
- Testing
- High load, Moderate load, Healthy adults - High load
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- European University Miguel de Cervantes
Burpee Exercise, Water Exercises
Water Based Burpee Exercises on Functional Capacity in Poste-menopausal Women After Thyroidectomy
Skeletal muscle mass plays an important role with both metabolism and functional capacity. It is well established that the aging process leads to a significant decline in both muscle mass and strength which is associated with…
- Conditions
- Burpee Exercise, Water Exercises, Functional Capacity, Postmenopausal
- Trial name
- NCT07052279
- Testing
- water based burpee exercises, aerobic exercises
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Al-Zaytoonah University of Jordan
Healthy
CArdioMEtabolic Function and Reserve Capacity in Healthy Adults: The CAMERA Study
The purpose of this study is to evaluate pulmonary capillary wedge pressure (PCWP) and other hemodynamic measurements at rest and during exercise in healthy volunteers across the age spectrum.
- Trial name
- CAMERA (NCT06220396)
- Testing
- Right Heart Catheterization with Hemodynamics and Limited Echocardiogram, Magnetic Resonance Imaging (MRI), Dual X-ray absorptiometry (DEXA) scan
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic