Clinical trials: Functional Cognitive Disorder
Stroke, Epilepsy
Coronary and Cerebral Microvascular Dysfunction in Neurological Diseases
Neurological and cardiovascular diseases are increasing in relative and absolute terms globally, and pose a major burden in terms of morbidity, mortality, quality of life and healthcare costs.
- Conditions
- Stroke, Epilepsy, Transient Global Amnesia (TGA)
- Trial name
- G-HeBra (NCT07009990)
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Pre Diabetes, Vascular Stiffness
Dietary Exchanges With Avocado and Mango in Pre-diabetes
The research is designed as a randomized, 2-arm, parallel, controlled, human clinical trial to investigate the effects of avocado and mango consumption for 8 weeks on indices of macro- and micro- vascular function in individuals…
- Conditions
- Pre Diabetes, Vascular Stiffness, Vascular Dilation, Cognitive Change
- Trial name
- AVMa (NCT05353790)
- Testing
- Meals + snacks: control, Meals + snacks: Avocado mango
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Traumatic Brain Injury
Impact of Traumatic Brain Injury on Cognitive Function, Balance and Functional Independence in Children
The purpose of the study is to determine the impact of different levels of traumatic brain injury on cognitive function, functional independence and balance on children and relation of cognitive dysfunction, balance disturbance…
- Trial name
- Impact TBI (NCT07612410)
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Digestive System Diseases, Disorientation
Opioid Effects on Cognitive Function Following Colonoscopy
This study aims to compare the effects of fentanyl and alfentanil on postprocedural cognitive function in elective endoscopy. 150 patients will be enrolled in the study.
- Trial name
- NCT02267681
- Testing
- Fentanyl, Alfentanil, Propofol
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Perihan Ekmekçi
Attention Deficit Hyperactivity Disorder
Meta-cognitive Functional Intervention for Adults With ADHD: A Pilot Efficacy Study
The purpose of this study is to examine the initial efficacy of a psycho-social, metacognitive-functional intervention for Adults (Cog-Fun - A) with Attention Deficit Hyperactivity Disorder (ADHD).
- Trial name
- NCT02681575
- Testing
- Cog-Fun - A
- Where
- Israel
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Frailty Syndrome, Sarcopenia
Design and Validation of FEXO: A Playful Exercise Program for Institutionalized Frail Older Adults
This multicenter randomized controlled trial aims to evaluate the effectiveness of a playful multicomponent exercise intervention (FEXO - Fun Exercise for Older Adults) on intrinsic capacity, frailty, and functional health in…
- Trial name
- FEXO-FRAIL (NCT07133581)
- Testing
- FEXO (Fun Exercise for Older Adults)
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cardenal Herrera University
Breast Cancer
A Prospective Study to Evaluate the Effect of Systemic Adjuvant Therapy on the Cognitive Function of Breast Cancer Patients
The primary objective of this prospective pilot study is to examine the variation of cognitive function at various time-points in stage I-III breast cancer patients who have undergone or are undergoing adjuvant systemic therapy…
- Trial name
- NCT01596439
- Where
- Singapore
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Healthy Control Subjects, Schizophrenia Diagnosis
Understanding Lifespan Trajectories of Social Cognition, Brain Microstructure and Iron Dysregulation in Schizophrenia
This study aims to better understand how schizophrenia may affect social thinking, emotion regulation, brain function, and biological processes over time. Two groups will take part in the study: 1.
- Trial name
- NCT07856381
- Where
- Austria
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Older Adults Without Any Specific Clinical Condition
Impact of a Technology Mediated Dance Intervention
This study aims to investigate whether a technology-mediated dance impacts on psychosocial, physical and cognitive functions of the old adults when compared to usual activities.
- Trial name
- NCT05460039
- Testing
- Dance mediated by tecnhology
- Where
- Portugal
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Aveiro University
Multiple Sclerosis, Cognitive Rehabilitation
Randomised Controlled Clinical Trial of Cognitive Rehabilitation in Multiple Sclerosis
Despite the need for cognitive rehabilitation, there is a paucity of well-designed research studies to investigate treatment approaches or their effectiveness in MS.
- Trial name
- REACTIV (NCT01207856)
- Testing
- specific cognitive rehabilitation, non specific cognitive rehabilitation, no intervention
- Where
- France
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Cognitive Impairment, Functional Magnetic Resonance Imaging
Functional Magnetic Resonance Imaging (fMRI) of Brain in ICU Survivors With Cognitive Impairment
Long-term cognitive dysfunction greatly influences patient's quality of life after critical illness. However,its neurophysiological basis remains unknown.This is a 3 year fMRI study conducted at the Jiangyin people's Hospital.
- Conditions
- Cognitive Impairment, Functional Magnetic Resonance Imaging, Septic Shock, Inflammation
- Trial name
- NCT03946839
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jian-jun Yang
Obesity (Disorder), Systemic Inflammation Markers
Understanding How Gut and Brain Barriers Are Linked to Inflammation in Obesity
The goal of this observational study is to understand how obesity affects the function of the gut and blood-brain barriers in adults.
- Conditions
- Obesity (Disorder), Systemic Inflammation Markers, Intestinal Barrier Dysfunction, Blood Brain Barrier
- Trial name
- GUTBBB (NCT06787001)
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Resilience, Cognitive Function and Well-Being
Aging Resilience Through Microbiota Optimization and Regulation
Sarcopenia, characterized by the progressive loss of muscle mass and strength in older adults, is a key factor in health deterioration.
- Conditions
- Resilience, Cognitive Function and Well-Being, Muscle Function, Handgrip Strength Test, Insulin Sensitivity
- Trial name
- ARMOR (NCT06649981)
- Testing
- FMT capsule
- Where
- 2 sites in Chile
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Gonzalo Jorquera, PhD
Breast Cancer
Breast Cancer Survivorship & Work-Related Cognitive Limitation
The proposed study seeks to evaluate the relationship between biopsychosocial functioning and work-related cognitive limitation among employed breast cancer survivors in a cross-sectional study with healthy control group.
- Trial name
- BCSurvivorship (NCT02303145)
- Where
- United States
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Tara Emrani
Postoperative Complication, Cognitive Retention Disorder
Methylprednisolone Combined Electric-acupuncture on Cognitive Function
Postoperative cognitive dysfunction (POCD) refers to the patients in the central nervous system complications after general anesthesia and clinical manifestations of mental disorder, anxiety, personality changes, impaired memory…
- Trial name
- NCT02535039
- Testing
- Methylprednisolone, Physiological saline
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Memory Impairment, Sleep Disorder
Improving Patient Memory for Treatment for Mild Cognitive Impairment
The main empirical question to be addressed is: What types of memory support are most potent for patients who are experiencing a mild cognitive impairment (MCI) relative to non-MCI patients?
- Trial name
- NCT05668481
- Testing
- Transdiagnostic sleep and circadian intervention (TranS-C)
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Healthy
Effects of Vitamin D3 Supplementation on Cognitive Function in Community Dwelling Older Adults
Ireland is predicted to have the highest older adult population growth of any European Union country. A substantial economic and social challenge of this projected growth is the increased incidence of cognitive impairment and the…
- Trial name
- NCT02804841
- Testing
- Cholecalciferol -Vitamin D3
- Where
- Ireland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Dublin, Trinity College
Hypogonadism
Effects on the Brain of Lupron Induced Hypogonadotropic Hypogonadism With and Without Testosterone Replacement
There is evidence that suggests male sex hormones (androgens) play a significant role in brain (central nervous system) functioning.
- Trial name
- NCT00001412
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Congenital Heart Disease
Brain Function in Children With Congenital Heart Disease (CHD)
The purpose of the study is to determine whether the neurodevelopmental outcome and in particular executive functions in 9 to 14 year old school children with congenital heart disease who underwent cardiopulmonary bypass surgery…
- Trial name
- NCT02814539
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Bea Latal
Traumatic Brain Injury, Cognitive Impairment
Rehabilitation of Working Memory and Brain Plasticity After Traumatic Brain Injury: Plastim-MDTC
The aim of this study is to assess the brain correlates, as assessed with multimodal MRI, of working memory training in patients with severe traumatic brain injury (TBI)
- Trial name
- Plastim-MDTC (NCT03513133)
- Testing
- working memory training
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre d'Investigation Clinique et Technologique 805