Clinical trials: Functional Cognitive Disorder
Anxiety
40-Hz Audiovisual Stimulation in Schizophrenia Spectrum Disorders
This randomized, sham-controlled trial evaluated the effects of 40-Hz binaural beat music (BBM) combined with 40-Hz rhythmic photic stimulation (RPS) in adults with schizophrenia spectrum disorders.
- Trial name
- NCT07782034
- Testing
- 40-Hz Binaural Beat Music Combined With 40-Hz Rhythmic Photic Stimulation
- Where
- Taiwan
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- National Cheng Kung University
Aging, Cognitive Decline
The Effect of a Single Bout of Balance and Coordination Exercise on Cognitive Function in Elderly People
Individuals of advanced age are at higher risk of cognitive deterioration.A single bout of aerobic exercise was found to improve cognitive functions.
- Trial name
- NCT03420365
- Testing
- Aerobic exercise
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Dementia, Mild Cognitive Impairment
HOme-based Brain Monitoring With a GARment-EEG to Study Cognitive Decline in the Aging Population
This study will investigate the validity of the HOGAR EEG/PSG monitoring kit designed by Bitbrain as a tool for characterizing and assessing cognitive function in older adults, as well as for detecting and predicting cognitive…
- Conditions
- Dementia, Mild Cognitive Impairment, Dementia Alzheimers, Dementia, Mixed
- Trial name
- Hogar (NCT06993207)
- Testing
- Home Lab
- Where
- Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Bitbrain
Alzheimer's Disease, Dementia
A Study to Evaluate the Effects of MK-0249 and an Alzheimer's Disease Medication on Cognitive Function in Adults With Alzheimer's Disease (MK-0249-023)
This study will evaluate acute symptomatic improvements in cognitive performance in healthy elderly participants with mild-to-moderate Alzheimer's disease.
- Trial name
- NCT00874939
- Testing
- MK-0249 7.5 mg, MK-0249 25 mg, Donepezil 5mg
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Cognitive Impairment, Mild, Executive Dysfunction
Does Computerized Cognitive Training Improve Executive Functioning in the Older Adult?
Explanation of the study: As the older adult population continues to rise, so will normal cognitive aging. This increase raises concern for maintaining cognitive function and possibly delaying the onset of disorders such as…
- Trial name
- CCT (NCT03170492)
- Testing
- RehaCom Computerized Cognitive Training for 480 minutes, Pencil-and-Paper Cognitive Training for 480 minutes
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of the Sciences in Philadelphia
Healthy
Phase I Single and Multiple Escalating Dose Study of RGN1016 in Healthy Male Subjects
This is a double-blind, randomized, placebo-controlled, dose-escalating, single dose and multiple dose study.
- Trial name
- NCT02820155
- Testing
- RGN1016
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Schizophrenia, Cognitive Impairment
Functional Magnetic Resonance Imaging Study in Schizophrenia Patients and Correlation With Cognitive Impairments
1. Comparison of functional activity at different brain areas related to different cognitive domains e.g. Memory, visuospatial abilities, executive functions, attention, concentration, language, orientation in schizophrenia to…
- Trial name
- NCT06471179
- Testing
- Functional MRI
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pain, Fatigue
Fatigue in Chronic Pain - Cognition, Emotional Aspects, Biomarkers, and Neuronal Correlates
The investigators will examine mental/cognitive as well as cognitive functions (executive functions, attention functions, processing speed, learning and memory) in 200 patients with chronic pain and 36 healthy controls.
- Conditions
- Pain, Fatigue, Cognitive Impairment
- Trial name
- NCT05452915
- Testing
- Neuropsychological (NPA), Imaging, Inflammatory biomarkers
- Where
- 3 sites in Sweden
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Danderyd Hospital
Mountain Sickness
Three New Ideas to Protect Special Forces From the Stress of High Altitude
Acute Mountain Sickness (AMS) is a well-documented syndrome that affects 42% of non-acclimatized individuals traveling to altitudes above 10,000 feet.
- Trial name
- NCT02463357
- Testing
- Quercetin, Nifedipine extended release, Methazolamide
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Cognitive Change
Executive Function Training for Children and Adolescents
The goal of this clinical trial is to evaluate how different approaches to executive function (like adding game-like features, varying the number of tasks, and providing coaching) can enhance executive function outcomes in…
- Trial name
- NCT07147894
- Testing
- Nongamified N-back training, Gamified N-back training, Multiple Domain Training
- Where
- United States
- Volunteers
- 780 people, healthy volunteers welcome
- Sponsor
- Northeastern University
Postoperative Complication, Cognitive Retention Disorder
Methylprednisolone Combined Electric-acupuncture on Cognitive Function
Postoperative cognitive dysfunction (POCD) refers to the patients in the central nervous system complications after general anesthesia and clinical manifestations of mental disorder, anxiety, personality changes, impaired memory…
- Trial name
- NCT02535039
- Testing
- Methylprednisolone, Physiological saline
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Attention Deficit Hyperactivity Disorder
Taekwondo Practice in Adolescents With Attention Deficit Hyperactivity Disorder
Attention Deficit Hyperactivity Disorder (ADHD) is one of the most common neuro-developmental/behavioral disorders among adolescents.
- Trial name
- NCT03678844
- Testing
- Taekwondo practice, CONTROL
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Genova
COPD
Effects of Combined Cognitive Rehabilitation in COPD Patients
This study was to examine the effect of endurance training combined with cognitive training in patients with COPD. The intervention group underwent Cognitive Training added to Endurance Training and the control group underwent…
- Trial name
- NCT03907839
- Testing
- clinical trials
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Faculty of Medicine, Sousse
Multiple Sclerosis
Study of Social Cognition by Morphological and Functional Imaging in Multiple Sclerosis Patients
In recent years, studies have brought knowledge of the difficulties of social cognition in Multiple Sclerosis (MS). The brain tissue alteration at the origin of these difficulties in social cognition mechanisms remain poorly…
- Trial name
- SOCOG-MS (NCT02290587)
- Testing
- Brain MRI - Clinical and cognitive evaluation, MRI
- Where
- France
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Musculoskeletal Pain, Cognitive Change
Health, Wellbeing and Performance in Law Enforcement Workers
This study aims to assess current health and fitness of law enforcement workers in various roles, and to evaluate the impact of an exercise intervention on markers on physical and mental wellbeing in this population.
- Conditions
- Musculoskeletal Pain, Cognitive Change, Occupational Stress, Inflammation
- Trial name
- NCT04204486
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University College, London
Nicotine Dependence
Brain Networks and Addiction Susceptibility
Background: The risk for becoming addicted to drugs varies from person to person, even among those using similar drugs in a similar way.
- Trial name
- NCT01924468
- Testing
- Oral methylphenidate and Oral haloperidol
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Healthy, Older Adults
The Combined Effect of Dietary Nitrate and Caloric Restriction on Cognitive and Vascular Function.
This pilot study will compare the effect of combining dietary nitrate and caloric restriction versus dietary nitrate alone. The participant will be contacted, having responded to an advertisement on social media and posters, to…
- Conditions
- Healthy, Older Adults, Overweight and Obesity
- Trial name
- CRNitrateMRI (NCT06151015)
- Testing
- Nitrate-rich beetroot juice plus calorie-restricted diet, Nitrate-rich beetroot juice plus weight-maintenance diet
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Moira Taylor
Aging, Sarcopenia
Effect of Immunocal® With Exercise Versus Casein With Exercise on Aging Processes in Elderly Persons
Aging is typically associated with a decrease in skeletal muscle mass and muscle function, which contributes decisively to disability in old age and to the loss of quality of life.Resistance exercise can increase muscle strength…
- Trial name
- NCT00935610
- Testing
- Immunocal, Casein
- Where
- Canada
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Immunotec Inc.
Brain Injury, Chronic
Investigating the Role of the Premotor Cortex in Higher Cognitive Functions
This project aims at understanding better the role of the frontal lobe of the brain in our capacity to perceive visual information consciously, and also, in our capacity to perceive others' actions.
- Trial name
- NCT00842413
- Where
- France
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
COPD
Impairments That Affect Correct Inhaler Use in COPD
INHALE is a one-year, multi-site observational research study funded by Viatris, with two aims: 1. Determine the prevalence of both cognitive impairment and impaired manual dexterity in stable out-patients with chronic…
- Trial name
- INHALE (NCT06135324)
- Where
- 9 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- COPD Foundation