Clinical trials: Functional Cognitive Disorder
Diabetes Mellitus, Type 2
Colostrum Supplements Effect on the Physical Performance and Cognitive Function
The goal of this interventional Randomized clinical is to compare the effect of colostrum pharmaceutical preparation and placebo in a sample of Iraqi participants. The main questions to answer are: 1.
- Trial name
- NCT06007430
- Testing
- Colostrum Capsule 500 mg (Colostrum® 500 mg Veg Capsules, nowfoods®, Illinois, USA)
- Where
- Iraq
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Al-Mustafa University College
Metabolic Syndrome, Inflammation
Effects of Berries and Vegetables on Cardiometabolic Risk Markers and Cognitive Functions
The purpose of the study is to study the potential anti-inflammatory- and metabolic effects of polyphenols and dietary fibres in a product based on a mixture of several Swedish berries and vegetables that is known to have high…
- Conditions
- Metabolic Syndrome, Inflammation, Aging, Fermentation
- Trial name
- NCT01562392
- Testing
- berries and vegetables, control product
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lund University
Depression, Dementia
Antidepressant Medication Plus Donepezil for Treating Late-life Depression
This study will determine the effectiveness of combining escitalopram, venlafaxine, or duloxetine with donepezil, a medication used in Alzheimer's disease, in improving memory, concentration, attention, and problem solving…
- Trial name
- NCT00177671
- Testing
- Escitalopram, Donepezil, Venlafaxine
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Sleep Deprivation, Sleep
Effects of Napping in Sleep-Restricted Adolescents
To examine the neurobehavioural responses to two successive cycles of sleep restriction and recovery in adolescents, and to determine the benefits of napping on cognitive performance, alertness, and mood.
- Trial name
- NCT02838095
- Testing
- Nap
- Where
- Singapore
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Duke-NUS Graduate Medical School
Cognition, Affect (Mental Function)
BiomeBakery Project
This study aims to investigate the chronic effects of prebiotic fibre-fortified functional bakery product on cognitive, affective, inflammatory, metabolic, and anthropometric outcomes in healthy adults aged 60-75 years with mild…
- Conditions
- Cognition, Affect (Mental Function), C Reactive Protein
- Trial name
- NCT06796712
- Testing
- Prebiotic fibre fortified bread roll, Regular bread roll
- Where
- United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Reading
Alzheimer Disease
Effects of Enriched Gardens in Nursing Home Residents With Dementia
Comparing the effect of the frequentation of an enriched garden vs sensory conventional garden by nursing home residents with Alzheimer disease.
- Trial name
- NCT04903171
- Testing
- INCENTIVE VISITING A GARDEN : ENRICHED OR CONVENTIONAL SENSORY GARDEN
- Where
- France
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- RIVAGES
Diabetes Mellitus, Type 2, Diabetes Mellitus Type 2 in Obese
From Skin Fibroblasts to Neural Stem Cells to Investigate in Vitro the Impact of Diabetes on Adult Neurogenesis
Obesity and glucose intolerance or overt diabetes are increasing at an alarming rate in the population, and are bound to become a public health issue and a major cause of disability, loss of independence and high social costs in…
- Conditions
- Diabetes Mellitus, Type 2, Diabetes Mellitus Type 2 in Obese, Diabetes Mellitus Type 2 in Nonobese, Obesity
- Trial name
- NCT05755321
- Testing
- Skin biopsy
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Glaucoma, Mild Cognitive Impairment
Assessing Neurovisual Function in Patients With Cognitive Impairment
The aim of this study is to measure fitness to drive in patients with a visual and a cognitive impairment. To do so, Ocusweep is used in patients with glaucoma and Mild Cognitive Impairment.
- Conditions
- Glaucoma, Mild Cognitive Impairment, Glaucoma and Mild Cognitive Impairment, Healthy
- Trial name
- NCT03333096
- Testing
- Ocusweep test battery, Neuropsychological test battery
- Where
- Finland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Cognitive Impairment, Dementia
Predicting MRI Abnormalities With Longitudinal Data of the Whitehall II Substudy
Follow-up study within the Whitehall II study, selecting 800 participants for further neuropsychological, clinical and imaging (MRI) examinations to examine brain structure and function in relation to age-related diseases and the…
- Conditions
- Cognitive Impairment, Dementia, Affective Disorders
- Trial name
- NCT03335696
- Where
- United Kingdom
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Leukocytosis, Triglycerides
Acute High Fat Bulletproof Coffee vs Black Coffee on Metabolism, Inflammation and Cognitive Function in Healthy Adults
This study will determine whether acute ingestion of a high fat "Bulletproof Coffee" will lead to changes in plasma triglycerides, immune cell function, as well as cognitive function when compared to a black coffee.
- Conditions
- Leukocytosis, Triglycerides, Cognitive Function, Inflammatory Response
- Trial name
- NCT04307979
- Testing
- High-fat coffee, Black coffee
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Parkinson Disease, Prodromal Stage
Slowing Cognitive Decline in Alpha-synucleinopathies by Enhancing Physical Activity
α-Synucleinopathies, including Parkinson's disease and dementia with Lewy bodies, are the second most common neurodegenerative diseases.
- Conditions
- Parkinson Disease, Prodromal Stage, Neurodegenerative Diseases, Basal Ganglia Diseases
- Trial name
- ALPHA-FIT (NCT07324330)
- Testing
- Increase of physical activity volume and intensity with the use of a motivational smartphone application
- Where
- Germany
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bonn
Schizophrenia, Schizoaffective Disorder
Effect of Varenicline on Cognitive Function in Cigarette Smokers With Schizophrenia
Smokers with schizophrenia have more difficulties quitting smoking than smokers without a mental disorder. Varenicline (Champix) is a new stop smoking medication with a unique mechanism of action.
- Trial name
- NCT01093365
- Testing
- Varenicline
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Obesity
The Influence of Obesity on Level of Depression and Cognitive and Executive Functions
The proposed study is a randomized, open, comparative research involving an intervention group and two control groups. The aims of the study are: 1.To compare levels of depression in female adolescents with obesity and a control…
- Trial name
- NCT03087994
- Testing
- Nutritional guidance intervention
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Brain Damage, Chronic
The Effect of tDCS on Subcortical Brain Functioning
This research is being done to determine whether transcranial direct current stimulation (tDCS) can improve certain abilities related to cognition, emotion and/or physical functioning in individuals with subcortical brain damage.
- Trial name
- NCT01602276
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Physical Activity, Sedentary Behavior
Exploring Virtual Reality Adventure Training Exergaming
The current project aims to design and implement an 8-week Virtual Reality Adventure Therapy Exergaming (V-RATE) intervention focused on women veterans.
- Conditions
- Physical Activity, Sedentary Behavior, Depression, Cognitive Function
- Trial name
- V-RATE (NCT05563805)
- Testing
- Virtual Reality-based physical activity intervention
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Neurocognitive Disorders, Anesthesia
Total Intravenous Versus Inhalational Anesthesia- A Geriatric Anesthesia Study
Traditionally, general anesthesia is maintained with inhalational anesthesia (GAS), but there is a gap in knowledge regarding whether intravenous anesthesia (IV) can prevent deleterious postoperative outcomes in the geriatric…
- Conditions
- Neurocognitive Disorders, Anesthesia, Post-operative Delirium, Post-operative Cognitive Dysfunction
- Trial name
- TIVA GAS (NCT06036095)
- Testing
- Sevoflurane, Propofol
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Hypertension, Dyslipidemia
Supplementation With Flaxseed Oil in the State of Rio de Janeiro
The purpose of this study is to evaluate the effect of supplementation with flaxseed oil combined with a nutritional counseling in reducing cardiovascular risk factors in homocysteine , biomarkers of inflammation, oxidative…
- Trial name
- NCT01604681
- Testing
- Flaxseed Oil
- Where
- Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Hyperalgesia, Allodynia
Fenobam on Heat/Capsaicin Induced Hyperalgesia in Healthy Volunteers
Our goal is to demonstrate that healthy volunteers treated with fenobam will develop a significantly reduced area of cutaneous hyperalgesia compared to volunteers treated with placebo, after exposure to the heat/capsaicin model…
- Trial name
- NCT01981395
- Testing
- Fenobam
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Laura Cavallone
Parkinson Disease
The Role of DLOTCA-G in the Cognitive Function Evaluation of Parkinson's Patients
The purpose of this study is to evaluate the usefulness of Dynamic Loewenstein's Occupational Therapy and Cognitive Assessment Scale for Geriatrics (DLOTCA-G) in parkinson patients.
- Trial name
- NCT06131619
- Testing
- assesment of cognitive parameters with DLOTCA-G
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
HIV/AIDS
Assessment of Cognitive Functioning as it Relates to Risk for Suicide in Veterans With HIV/AIDS
The purpose of this project is to gather pilot data related to exploring relationships between cognitive impairment and/or psychiatric distress and suicidal thoughts and/or behaviors in Veterans with Human Immunodeficiency Virus…
- Trial name
- NCT01749007
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System