Clinical trials: Functional Cognitive Disorder
Migraine Disorders
Cognitive Function and Autonomic Regulation in Patients With Migraine
Individuals with migraine have impaired cognitive function and worse autonomic function compared to individuals without migraine.
- Trial name
- NCT04272229
- Testing
- Cognition, Sympathetic Nervous System, Concentratio and Attention
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fortaleza University
Type 1 Diabetes, Hypoglycemia
Brain Ketone Metabolism in Type 1 Diabetes
This study is designed to examine the value of infusing BHB in type 1 diabetic subjects during experimentally induced hypoglycemic episode in conjunction with testing of cognitive function.
- Trial name
- NCT02471040
- Testing
- Beta-hydroxybutyrate, Normal Saline
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Yale University
Concussion (Diagnosis)
Sports-related Concussion: Physiological, Biomechanical and Cognitive Methodology
The study aims to investigate the changes in physiological, biomechanical and cognitive performance under a traumatic sport-event (i.e., rugby match).
- Trial name
- NCT04841876
- Testing
- rugby matches
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
Mental Health Wellness 1, Work Related Stress
Mental Balance Study
The proposed design is a randomised, double-blind, controlled, crossover intervention assessing the effects of an active intervention, containing Scutellaria baicalensis and Crataegus, versus placebo, on stress, cognition, sleep…
- Trial name
- NCT05757050
- Testing
- Re-Focus "Verum" Tablets
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- A. Vogel AG
Quality of Life, Aging
Functional Outcomes of Stay Strong Stay Healthy Program
Strength training can increase muscle mass and strength while improving bone density and reducing risk for osteoporosis and related fractures.
- Conditions
- Quality of Life, Aging, Memory Loss, Cardiovascular Diseases
- Trial name
- NCT02677363
- Testing
- Resistance Exercise
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Quality of Life, Surgery
Determination of the Effect of Puzzle Use in Elderly Patients
The aim of this study is to determine the effects of the use of a simple, reliable and cost-effective puzzle on post-operative cognitive function changes, postoperative recovery, and quality of life using questionnaires and…
- Conditions
- Quality of Life, Surgery, Postoperative Confusion, Cognitive Dysfunction
- Trial name
- NCT05796830
- Testing
- Puzzle application
- Volunteers
- healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Dementia
Occupational Therapy Programme of Patients With Dementia Performing Activities of Daily Living
To assess the effectiveness of the Stimulation of Activities of Daily Living (SADL) Occupational Therapy programme on the independence of ADL by persons with dementia who are institutionalized.
- Trial name
- OTSALD (NCT02199353)
- Testing
- Stimulation of Activities Daily Living, Conventional ADLOccupational Therapy
- Where
- Spain
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Extremadura
Dementia
Examining the Relationship Between Hormone Therapy (HT) and Cognitive Function (The WHIMS-ECHO Study)
This is a prospective, observational study of the cohort of older post-menopausal participants in the WHI Memory Study, a sub-cohort of participants in the WHI Hormone Trials.
- Trial name
- WHIMS-ECHO (NCT00745056)
- Where
- United States
- Volunteers
- 2,922 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Cognitive Decline, Cognitive Dysfunction
Open-label, Post-marketing, Prospective Study to Assess Impact of COVID-19 on Cognitive Function in Patients
The objective of this study is to compare the impact of the coronavirus disease (SARS-CoV-2, or COVID-19) on cognitive function in the population of patients who have been diagnosed, treated and recovered from the COVID-19…
- Conditions
- Cognitive Decline, Cognitive Dysfunction, Brain Health, Post CoV-2 Syndrome
- Trial name
- COVID19 (NCT04950673)
- Testing
- Cognivue
- Where
- 4 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Cognivue, Inc.
Cognitive Change, Cognitive Impairment
The Everyday Function Intervention Trial
Loss of independence, cognitive decline, and difficulties in everyday function are areas of great concern for older adults and their families.
- Conditions
- Cognitive Change, Cognitive Impairment, Healthy Aging, Dementia
- Trial name
- EFIT (NCT04651582)
- Testing
- Cognitive Training, Cognitive Stimulating Activities
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Clemson University
Healthy Individuals (Controls), Parkinson Disease
Motor Learning in Health and Movement Disorders: Role of Physical Activity and Advanced Devices
The goal of this clinical trial is to investigate motor responses in healthy subjects and patients with movement disorders, brain and spinal cord injury, neuromuscular diseases, or cardiovascular diseases.
- Conditions
- Healthy Individuals (Controls), Parkinson Disease, Multiple Sclerosis, Alzheimer Disease
- Trial name
- Allena-mente (NCT07066137)
- Testing
- CAREN, Control group
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Mild Cognitive Impairment, NAD
The Effects of Nicotinamide Adenine Dinucleotide (NAD) on Brain Function and Cognition
The purpose of this study is to determine the effects of Niagen (nicotinamide riboside, vitamin B3), on NAD levels, brain function including cognition and blood flow in people diagnosed with mild cognitive impairment (MCI).
- Trial name
- NAD (NCT02942888)
- Testing
- Nicotinamide riboside, Sugar Pill
- Where
- 2 sites in United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Cognitive Function, Cognitive Decline
Phospholipid-rich Dairy Extract for Cognitive Function
This clinical trial aims to determine whether dietary phospholipid-rich dairy milk extract improves cognitive function in adults with mild cognitive impairment and to assess its safety.
- Trial name
- NCT07011680
- Testing
- Phospholipid-rich dairy milk extract
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Pusan National University Yangsan Hospital
Cognitive Change, Beta-Thalassemia
Assessment of Cognitive Function, Fatigue and Health Related Quality of Life in Children With Beta Thalassemia
This study aims to: Assess the cognitive function in children with beta thalassemia Evaluate the fatigue in beta thalassemic children Assess the health related quality of life measures in children with beta thalassemia.
- Conditions
- Cognitive Change, Beta-Thalassemia, Fatigue, Quality of Life
- Trial name
- NCT05469230
- Where
- Egypt
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gamma Oscillations, Healthy Adults
Investigating the Effectiveness of Personalized Optimal Gamma Auditory Frequency Stimulation Intervention on Cognitive Function Enhancement
This study aims to evaluate whether personalized gamma-frequency auditory stimulation enhances cognitive function and brain synchronization.
- Conditions
- Gamma Oscillations, Healthy Adults, Alzheimer's Disease (AD), Gamma Entrainment Using Sensory Stimuli (GENUS)
- Trial name
- NCT07690865
- Testing
- Personalized optimal gamma auditory frequency stimulation, Non-optimal gamma auditory frequency stimulation
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Cognitive Decline, Aging
Effects of a Colon-delivered Multivitamin Supplement on Brain Functioning, Immunometabolic- and Intestinal Markers in Ageing
COMBI is a multi-center, randomized controlled trial among 70 older adults at risk of cognitive decline. The main goal is to investigate the effect of a 6-week colon-delivered multivitamin supplementation on the gut-brain axis in…
- Trial name
- COMBI (NCT05675007)
- Testing
- Colon-delivered multivitamin supplement
- Where
- 2 sites in Netherlands
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Donders Centre for Cognitive Neuroimaging
Anhedonia, Cognitive Function
Pitolisant Effects on Affect and Cognition Exploratory Study (PEACE Study)
The goal of this study is to investigate the effects of selective histamine 3 antagonist pitolisant on brain function and cognition in healthy individuals. The main questions it aims to answer are: 1.
- Trial name
- PEACE (NCT05849675)
- Testing
- Pitolisant 17.8 MG [Wakix]
- Where
- United Kingdom
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Mild Cognitive Impairment, Healthy Aging
A Novel Computer-Based Functional Skills Assessment and Training Program
People with cognitive impairments such as Mild Cognitive Impairment (MCI), often experience difficulty performing everyday routine activities.
- Trial name
- NCT04679441
- Testing
- The Computerized Functional Skills Assessment and Training Program, Brain HQ Double Decision
- Where
- 2 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- i-Function, Inc.
Alcohol Aftereffects, Anxiety
A Clinical Study to Assess the Effects of JoyRise Recovery Powder on Mitigating Alcohol Aftereffects.
This study assesses the effectiveness of JoyRise Recovery Powder in reducing alcohol aftereffects, cognitive impairment, and anxiousness among participants aged 35-54 who consume alcohol.
- Conditions
- Alcohol Aftereffects, Anxiety, Cognitive Impairment
- Trial name
- NCT06575972
- Testing
- JoyRise Recovery Powder
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Joyrise
Aging, Nursing Homes
Effect of Sunlight Exposure and Outdoor Activities on Depression, Cognition and Quality of Life in the Elderly
Background: The transition to long-term care facility can be a stressful and emotional event for the elderly. The evidences showed that the prevalence of depression and the cognition impairment were higher in the…
- Conditions
- Aging, Nursing Homes, Depression in Old Age, Cognitive Impairment
- Trial name
- NCT03304301
- Testing
- sunlight exposure
- Where
- Taiwan
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Chiayi Christian Hospital