Clinical trials: Functional Cognitive Disorder
Atrial Fibrillation (AF), Stroke
Population-based Atrial Fibrillation Screening in Individuals With NT-proBNP Above Median in the Tromsø Study
The aim is to investigate whether screening with long-term ECG monitoring in individuals with elevated NT-proBNP leads to a lower incidence of ischeamic stroke and death from vascular causes.
- Conditions
- Atrial Fibrillation (AF), Stroke, NT-pro-BNP, Cognitive Function and Well-Being
- Trial name
- PAFS-Tromsø (NCT07343895)
- Testing
- Long term heart rythm monitoring by ECG247
- Where
- 2 sites in Norway
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Hepatitis C, Hepatitis B
Neurocognitive Functioning in Patients With Hepatitis C Pre- and Post-Treatment With Antiviral Medication
The estimated global prevalence of hepatitis C (HCV) infection is approximately 3% (170 million individuals). In Canada there are an estimated 240,000 people infected with HCV.
- Trial name
- NCT00188201
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Drug Addiction
Project on tDCS Intervention to Enhance Advanced Social Cognitive Functions in Drug Rehabilitation Individuals
This project aims to explore key brain functional and biochemical indicators associated with impaired advanced social cognition through an integrated approach encompassing unconscious control, conscious control, cognitive…
- Trial name
- NCT06888700
- Testing
- Transcranial direct current stimulation
- Where
- China
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Shaanxi Normal University
Cognitive Impairment, Cognitive Decline
A Mechanistic Study to Investigate tDCS and Working Memory in MCI Patients
The current study is a mechanistic study to evaluate working memory gains from application of transcranial direct current stimulation (tDCS) in older adults with mild cognitive impairments (MCI) compared to cognitively healthy…
- Trial name
- AIM (NCT05998031)
- Testing
- Active tDCS
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Florida
Obesity, Metabolic Syndrome
The Effect of Combined Aerobic Exercise and Calorie Restriction on Mood, Cognition, and Motor Behavior in Overweight and Obese Women
The benefits of weight-loss programs on mood state and cognitive and motor behavior remain unclear and are largely limited to those of calorie restriction (CR) or physical exercise alone.
- Trial name
- NCT04016909
- Testing
- aerobic exercise plus calorie restriction
- Where
- Lithuania
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Physical Disability
Multi-ingredient Nutrition Supplement in Older Adults
The aims of the present study are: i. To conduct a population study of body composition, muscle function and ability to undertake activities of daily living in elderly Irish individuals ii.
- Trial name
- NCT02001831
- Testing
- Supplement
- Where
- Ireland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Cognitive Functions
Cognitive Stimulation Therapy Group for Residential Home Residents With Dementia and Mild Cognitive Impairment
The research aims to investigate the effectiveness a cognitive stimulation therapy group for older adults with dementia and mild cognitive impairment living in residential homes.
- Trial name
- CSTSAGE (NCT07372066)
- Testing
- Cognitive Stimulation Therapy group, Calligraphy group
- Where
- Hong Kong
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- City University of Hong Kong
Metabolic Syndrome, Coronary Artery Disease
Brain, Cardiac Hemodynamics and Cognition During Exercise in Subjects With Various Cardiovascular Profiles
People with cardiovascular risk (CV) factors (obesity, diabetes, etc...) or established heart disease (such as coronary heart disease or chronic heart failure) often have cognitive dysfunction as compared to people without CV…
- Conditions
- Metabolic Syndrome, Coronary Artery Disease, Heart Failure
- Trial name
- COGNEX (NCT03018561)
- Testing
- Exercise and Cognitive testing
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Montreal Heart Institute
Mild Cognitive Impairment, MCI
Effects of Methylene Blue in Healthy Aging, Mild Cognitive Impairment and Alzheimer's Disease
A double-blind, placebo-controlled study that aims to investigate the effect of 2-week and 12-week administration of USP methylene blue (MB) on cerebral blood flow, functional connectivity, memory and attention cognitive…
- Conditions
- Mild Cognitive Impairment, MCI, Aging, Alzheimer's Disease
- Trial name
- MB2 (NCT02380573)
- Testing
- Methylene Blue, FD&C Blue # 2, Phenazopyridine hydrochloride
- Where
- United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Alzheimer's Disease
Alzheimer's Disease and Physiological, Cognitive Function and BDNF Levels of Plasma Adaptation After Exercise Training
Alzheimer's disease (AD) is a neurodegenerative disease leading to one of the most common forms of dementia in humans and memory disorder is one of the first symptoms that lead to diagnosis.
- Trial name
- MARAE (NCT02968875)
- Testing
- Endurance Training, therapeutic education meetings
- Where
- Martinique
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University Hospital Center of Martinique
Bipolar
Genetic Association Study Between Single Nucleotide Polymorphisms (SNPs) and Cognitive Performance in Young Bipolar Type I Patients: LICAVALGENE
This is a genetic association study of cognitive impairment in young bipolar disease type I patients without medications in mania, depression, hypomania or mixed states.
- Trial name
- Licavalgene (NCT00969930)
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Mild Cognitive Impairment (MCI), Parkinsons Disease (PD)
Study to Investigate Vagus Nerve Stimulation to Augment Executive Function in Healthy and Cognitively Impaired Populations
This study plans to learn more about how stimulating the vagus nerve through gentle electrical stimulation applied to the ear can affect decision-making, problem-solving, and other thinking abilities.
- Conditions
- Mild Cognitive Impairment (MCI), Parkinsons Disease (PD), Healthy Adult
- Trial name
- NCT07424365
- Testing
- transcutaneous auricular vagus nerve stimulation
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Post Traumatic Stress Disorder
MDMA-Assisted CBCT for PTSD vs CBCT RCT
This study aims to evaluate the safety, feasibility, acceptability, and effectiveness of MDMA-assisted Cognitive-Behavioral Conjoint Therapy (CBCT) versus CBCT alone for the treatment of Post-Traumatic Stress Disorder (PTSD).
- Trial name
- NCT06044675
- Testing
- MDMA assisted psychotherapy, Psychotherapy
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Remedy
Attention Deficit, Mobility
Cognitive and Postural Activities of Prematurely Born Children
Prematurely born children (PC) have academic difficulties related to poorer attention capabilities. Additionally, they often show excessive mobility, quoted as agitation.
- Conditions
- Attention Deficit, Mobility, Postural Activity
- Trial name
- COGNIPOST (NCT04275895)
- Testing
- Evaluation of different attention or/and postural activities
- Where
- France
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Schizophrenia, Schizoaffective Disorder
Effect of Single Dose Intranasal Insulin On Cognitive Function
The purpose of the study is to find out how a small dose of insulin might affect memory, the ability to concentrate, and improve your daily functioning in patients with schizophrenia and schizoaffective disorders.
- Trial name
- NCT00646581
- Testing
- Insulin (Humulin)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Anesthesia, Cognitive Dysfunction
Evaluation of Cognitive Functions by Cerebral Pulse Oximetry
General and Spinal Anesthesia can be used in geriatric patients in orthopedic surgery. Post-op cognitive dysfunction can be seen in orthopedic surgeries in this group of patients.
- Trial name
- NCT03827083
- Testing
- cerebral pulse oximetry
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tepecik Training and Research Hospital
Cerebral Palsy
Cognitive Functioning in Children and Adolescents With Cerebral Palsy
Background: Cerebral palsy (CP) is characterized by motor impairment but commonly involves more widespread difficulties, including cognitive impairment.
- Trial name
- CPCog-Youth-DK (NCT05921422)
- Testing
- Cognitive assessment
- Where
- 2 sites in Denmark
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cognitive Change, Sleep Deprivation
Sleep Deprivation Study
The purpose of this study is to evaluate the measures of brain function, both neurophysiological (event-related potentials (ERPs) and functional (cognitive assessments), in response to sleep deprivation.
- Conditions
- Cognitive Change, Sleep Deprivation, Caffeine
- Trial name
- NCT05560620
- Testing
- Sleep Deprivation, Caffeine, No Caffeine
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- NeuroCatch Inc.
Memory Loss, Cognitive Changes
Aging and Estrogen on Cortical Function
This study will focus on how estrogen affects parts of the brain associated with memory and how the effect of estrogen is altered with aging in postmenopausal women.
- Conditions
- Memory Loss, Cognitive Changes, Postmenopausal Symptoms
- Trial name
- NCT01268046
- Testing
- Estradiol oral capsule, transderman estrogen patch
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Fatigue, Cognitive Function
Radicle Energy VBMTM: A Study Assessing the Impact of Health and Wellness Products on Fatigue and Related Health Outcomes
Radicle Energy VBMTM: A randomized, double-blind, placebo- controlled direct-to-consumer study assessing the impact of health and wellness products on fatigue and related health outcomes.
- Conditions
- Fatigue, Cognitive Function, Global Mental Health, Sleep Disturbance
- Trial name
- NCT07653724
- Testing
- Energy Active Product 1
- Where
- United States
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Radicle Science