Clinical trials: Functional Cognitive Disorder
Autism
Functional MRI of Cognitive Control in Autism
This study aims to investigate the role of fronto-striatal circuits and cognitive control in the perseverative and inflexible behavior that is a defining feature of autism.
- Trial name
- NCT00463164
- Where
- Netherlands
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Bipolar Disorder (BD), Cognitive Impairment
TMS for Improving Cognitive Function in Bipolar Disorder
Bipolar disorder is a highly disabling psychiatric illness, and cognitive impairment is common in patients with bipolar depression as well as during remission, contributing substantially to functional disability and poorer…
- Trial name
- NCT07414147
- Testing
- Active Intermittent Theta Burst Stimulation, Online Cognitive Training
- Where
- China
- Volunteers
- 88 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Alzheimer Dementia, Alzheimer Disease
Treating Hyperexcitability in AD With Levetiracetam
The aim of this study is to explore the relationship between cortical hyperexcitability, abnormalities of brain network function, and cognitive dysfunction in human patients with AD and whether administration of the antiepileptic…
- Conditions
- Alzheimer Dementia, Alzheimer Disease, Dementia of Alzheimer Type, Mild Cognitive Impairment
- Trial name
- LeAD (NCT03875638)
- Testing
- Levetiracetam
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Inflammatory Bowel Diseases
Heart Rate Variability and Inflammatory Bowel Disease
The goals of this study are to test the effectiveness of a virtually delivered, group-based coping skills treatment program incorporating heart rate variability biofeedback to target autonomic dysfunction in youth diagnosed with…
- Trial name
- NCT06537258
- Testing
- Biofeedback Enhanced Treatment
- Where
- 3 sites in United States
- Volunteers
- 128 people
- Sponsor
- Emory University
Traumatic Brain Injury
Transcranial Direct Current Stimulation and Computer-based Training for the Traumatic Brain Injury Rehabilitation
Traumatic Brain Injury (TBI) is a serious public health problem due to its high mortality and morbidity rates, mainly affecting young adult males.
- Trial name
- NCT03382626
- Testing
- anodal tDCS, Computer-assisted training
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo General Hospital
Dementia, Neurocognitive Disorders
Cognitive Stimulation in Older Adults With Alzheimer's Disease
This multicentre study, employing a randomised controlled repeated measures experimental design, will be conducted in several Portuguese institutions that provide care and support services for older adults diagnosed with mild to…
- Conditions
- Dementia, Neurocognitive Disorders, Cognitive Impairment, Cognitive Dysfunction
- Trial name
- NCT07041008
- Testing
- Digital intervention, Physical/Analogue Intervention
- Where
- 39 sites in Portugal
- Volunteers
- 514 people
- Sponsor
- Rsocialform - Geriatria, Lda
Autism Spectrum Disorder
MOTOR PROFICIENCY IN RELATION TO COGNITIVE FUNCTIONS AND SEVERITY IN CHILDREN WITH AUTISM SPECTRUM DISORDERS
To investigate the relationship between cognitive function, the severity of autism spectrum disorder (ASD), and the development of fine and gross motor skills in children with ASD
- Trial name
- NCT06889233
- Testing
- measuring cognitive functions, severity of autism , gross and fine motor skills
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Cairo University
Exercise, Parkinson Disease
Comparing the Effects of Instability Resistance Training Versus Aerobic Training on Cognitive and Motor Improvements Found in Parkinson's Disease Participants
This study will be looking at the effects that instability resistance training and aerobic training, individually, have on the improvement of various motor and cognitive impairments present in individuals with Parkinson' disease.
- Trial name
- NCT03711955
- Testing
- Exercise
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Sun Life Financial Movement Disorders Research and Rehabilitation Centre
Psychotic Disorders, ADHD
Cognitive Remediation in Forensic Mental Health Care
Forensic patients often display cognitive deficits, particularly in the domain of executive functions, that represent a challenge to forensic rehabilitation.
- Conditions
- Psychotic Disorders, ADHD, TBI (Traumatic Brain Injury), Aggression
- Trial name
- CRFMHC (NCT04610697)
- Testing
- Cognitive Remediation, Active Control
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- The Royal Ottawa Mental Health Centre
Acute Brain Injury, Cognitive Dysfunction
Cognitive Function and Health-related Quality of Life After Neuro-intensive Care
The study will provide information on cognitive impairment and Health related quality of life in patients surviving 12 months after acute brain injury, generate a hypothesis of useful variables to predict cognitive impairment or…
- Conditions
- Acute Brain Injury, Cognitive Dysfunction, Delirium, Sepsis
- Trial name
- COGNI (NCT04881097)
- Testing
- no intervention
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Diabetes Mellitus, Type 2, Metabolic Syndrome X
Functional MRI Biomarkers of Cognitive Decrements in Diabetes
The exact neuronal mechanism underlying the cognitive decline associated with diabetes mellitus type 2 (DM2) still remains to be elucidated.
- Conditions
- Diabetes Mellitus, Type 2, Metabolic Syndrome X, Mild Cognitive Impairment
- Trial name
- NCT01705210
- Where
- Netherlands
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Preterm Birth, Psychological Distress
Expected and Actual Preterm-Birth and Parental Distress: Impact on Children's Mental Health
The purpose of the present study is the assessment of the mental health and cognitive development of children 6-11 years after premature or term birth.
- Conditions
- Preterm Birth, Psychological Distress, Mental Health, Cognitive Functioning
- Trial name
- NCT06627140
- Testing
- Diagnostic procedures
- Where
- Germany
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Goethe University
Breast Cancer, Chemotherapeutic Agent Toxicity
Effects of Chemotherapy on the Brain in Women With Newly Diagnosed Early-Stage Breast Cancer
RATIONALE: Gathering information over time from laboratory tests, imaging scans, and assessment tests may help doctors learn more about the side effects of chemotherapy and plan the best treatment.
- Conditions
- Breast Cancer, Chemotherapeutic Agent Toxicity, Cognitive/Functional Effects, Fatigue
- Trial name
- NCT00755313
- Testing
- trastuzumab, aromatase inhibition therapy, carboplatin
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cognitive Function, Anxiety
A Virtual Clinical Trial to Examine the Effect of Magnesium Choline Citrate on Cognitive Function and Anxiety in Healthy Adolescents and Adults
The goal of this clinical trial is to examine the effect of Magnesium Choline Citrate on cognitive function and anxiety in healthy adolescents and adults.
- Trial name
- NCT07685613
- Testing
- Magnesium Choline Citrate
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nutrisol, LLC
Psychotic Disorders, Schizophrenia
Examining the Efficacy of a Virtual Reality Cognitive Remediation Program for People Living With Psychosis
Individuals living with a psychotic disorder often experience changes to their thinking and social skills that can lead to challenges with work, school, relationships and living independently.
- Conditions
- Psychotic Disorders, Schizophrenia, Schizo Affective Disorder
- Trial name
- NCT05973110
- Testing
- Cognitive Remediation, Active Control
- Where
- Canada
- Volunteers
- 52 people
- Sponsor
- The Royal Ottawa Mental Health Centre
Hearing Loss, Sensorineural, Bilateral Vestibulopathy
Effect of Hearing Loss and Vestibular Decline on Cognitive Function in Older Subjects
The world population has been growing and aging dramatically, with a rising prevalence of dementia. Worldwide, around 50 million people have dementia, with 10 million new cases added every year.
- Conditions
- Hearing Loss, Sensorineural, Bilateral Vestibulopathy, Alzheimer Disease, Mild Cognitive Impairment
- Trial name
- GECkO (NCT04385225)
- Testing
- Longitudinal follow-up
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Iron-deficiency, Iron Deficiency Anemia
Fatigue, Quality of Life, Cognitive Function and Physical Ability in Patients Suspected of Colorectal Malignancy
The aim is to investigate if iron deficiency at the time of colorectal cancer diagnosis has an influence on fatigue, quality of life, cognition and physical ability.
- Conditions
- Iron-deficiency, Iron Deficiency Anemia, Colorectal Cancer, Fatigue
- Trial name
- NCT04749589
- Testing
- iron deficiency
- Where
- 3 sites in Denmark
- Volunteers
- 200 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Schizophrenia, Schizoaffective Disorder
Optimizing CBSST With Executive Function Training for Schizophrenia (R33)
This randomized controlled clinical trial will test a blended intervention that combines Executive Function Training with Cognitive-Behavioral Skills Training (E-CBSST).
- Trial name
- ECBSST R33 (NCT07658391)
- Testing
- E-CBSST, E-SC
- Where
- 2 sites in United States
- Volunteers
- 106 people
- Sponsor
- University of California, San Diego
Dementia, Neurocognitive Disorders
Prefrontal Cortex Dynamics of the Elderly During a Cognitive Stimulation Programme
This research aims to evaluate the effect of cognitive stimulation (CS) on the functioning of the prefrontal cortex (PFC), seeking an analysis of both cerebral hemodynamics in neuroplasticity and aspects related to the initiation…
- Conditions
- Dementia, Neurocognitive Disorders, Cognitive Impairment, Cognitive Dysfunction
- Trial name
- NCT04693611
- Testing
- Individual cognitive stimulation therapy (iCST), Functional near-infrared spectroscopy (fNIRS)
- Where
- Portugal
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- CEDIARA - Assoc. Solidariedade Social de Ribeira de Fráguas
Mild Cognitive Impairment
Memory Training in Patients With Amnestic Mild Cognitive Impairment
Preview research reports evidence of cognitive plasticity among individuals with amnestic Mild cognitive Impairment, and small-size studies have suggest that this population can benefit from memory training.
- Trial name
- NCT01978353
- Testing
- Memory Training, Psychoeducation
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo General Hospital
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