Clinical trials: Functional Cognitive Disorder
Acquired Brain Injury, Executive Function Disorder
Goal Management Training (GMT) for Improvement of Cognitive Control Function After Acquired Brain Injury
The goal of this clinical trial is to investigate predictors of treatment outcome, and the effect of individual treatment components of Goal Management Training (GMT) for improvement of cognitive control function in people with…
- Trial name
- NCT06604000
- Testing
- GMT Usual, GMT Cuing, GMT Boost
- Where
- Norway
- Volunteers
- 116 people
- Sponsor
- St. Olavs Hospital
Mild Cognitive Impairment
Functional MRI Changes Resulting From the Feuerstein Program in Older People With Mild Cognitive Impairment (MCI)
Background: The Feuerstein Instrumental Enrichment Program was designed to prevent mental deterioration and preserve cognitive abilities among people aged 60 and above.
- Trial name
- NCT03447236
- Testing
- Feuerstein Program
- Where
- Israel
- Volunteers
- 28 people
- Sponsor
- Rambam Health Care Campus
Mild Cognitive Impairment
The Effects of a Line Dance Program on Cognitive Function, Physical Function, and Quality of Life in Older Adults With Mild Cognitive Impairment
This study aims to evaluate the effects of a structured line dance program on cognitive function, physical performance, and quality of life in older women with mild cognitive impairment (MCI).
- Trial name
- LD-MCI (NCT07058844)
- Testing
- High-BPM Line Dance, Low-BPM Line Dance, Usual Daily Activity
- Where
- China
- Volunteers
- 75 people
- Sponsor
- Wanyu Shu
Mild Cognitive Impairment (MCI), Parkinsons Disease (PD)
Study to Investigate Vagus Nerve Stimulation to Augment Executive Function in Healthy and Cognitively Impaired Populations
This study plans to learn more about how stimulating the vagus nerve through gentle electrical stimulation applied to the ear can affect decision-making, problem-solving, and other thinking abilities.
- Conditions
- Mild Cognitive Impairment (MCI), Parkinsons Disease (PD), Healthy Adult
- Trial name
- NCT07424365
- Testing
- transcutaneous auricular vagus nerve stimulation
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Post Traumatic Stress Disorder
MDMA-Assisted CBCT for PTSD vs CBCT RCT
This study aims to evaluate the safety, feasibility, acceptability, and effectiveness of MDMA-assisted Cognitive-Behavioral Conjoint Therapy (CBCT) versus CBCT alone for the treatment of Post-Traumatic Stress Disorder (PTSD).
- Trial name
- NCT06044675
- Testing
- MDMA assisted psychotherapy, Psychotherapy
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Remedy
Stroke
Robotic Rehabilitation and Cognitive Functions
A recent multicenter study of the Fondazione Don Gnocchi (FDG) Robotic Rehabilitation Group (NCT02879279) showed the efficacy of robotic rehabilitation in upper limb motor recovery after stroke using a set of robots and…
- Trial name
- NCT04164381
- Testing
- Robotic assisted intervention
- Where
- Italy
- Volunteers
- 51 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Attention Deficit, Mobility
Cognitive and Postural Activities of Prematurely Born Children
Prematurely born children (PC) have academic difficulties related to poorer attention capabilities. Additionally, they often show excessive mobility, quoted as agitation.
- Conditions
- Attention Deficit, Mobility, Postural Activity
- Trial name
- COGNIPOST (NCT04275895)
- Testing
- Evaluation of different attention or/and postural activities
- Where
- France
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Mild Cognitive Impairment
Effects of an Exercise Snacking Intervention on Cognitive Function in Patients With Mild Cognitive Impairment: A Nationwide Multicenter Randomized Controlled Trial
This multicenter randomized controlled trial aims to evaluate the effects of a Baduanjin-based exercise snacking intervention on cognitive function in older adults with mild cognitive impairment (MCI).
- Trial name
- ES-MCI (NCT07822867)
- Testing
- Baduanjin-Based Exercise Snacking
- Volunteers
- 240 people
- Sponsor
- Peking University
Schizophrenia, Schizoaffective Disorder
Effect of Single Dose Intranasal Insulin On Cognitive Function
The purpose of the study is to find out how a small dose of insulin might affect memory, the ability to concentrate, and improve your daily functioning in patients with schizophrenia and schizoaffective disorders.
- Trial name
- NCT00646581
- Testing
- Insulin (Humulin)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Functional Autonomy Level
Optimization of Drug Prescribing in an Elderly Population of Geriatric Consultations
Aging is often associated with multiple chronic conditions conducting increased consumption of drugs. Drug therapy is necessary for the treatment of many diseases.
- Trial name
- OPTIM (NCT02740764)
- Testing
- Optimization of drug prescribing
- Where
- 2 sites in France
- Volunteers
- 302 people
- Sponsor
- Hospices Civils de Lyon
Prostate Cancer
Perioperative Changes of Cognitive Function According to Jugular Vein Insufficiency in Robot-assisted Prostatectomy
Internal jugular vein (IJV) is the main pathway of cerebral venous drainage and it has valve system to prevent retrograde blood flow to the brain.
- Trial name
- NCT01905488
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Yonsei University
Neurological Diseases or Conditions, Psychiatric Diseases
Understanding the Role of Monoaminergic Neurotransmitters in Cognitive Functions Using Fast-cyclic Voltammetry in Patients With Neurological and Psychiatric Diseases Eligible for Neurosurgical Treatment (COGAMINE)
This study aims at dynamically mapping local variations in the concentrations of monoaminergic neurotransmitters (for e.g. dopamine, serotonin and noradrenaline) in the human brain using fast-scan cyclic voltammetric recordings…
- Conditions
- Neurological Diseases or Conditions, Psychiatric Diseases, Candidates for Deep Brain Stimulation, Candidates for Invasive S-EEG
- Trial name
- COGAMINE (NCT06853977)
- Testing
- Cognitive tasks
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier St Anne
Anesthesia, Cognitive Dysfunction
Evaluation of Cognitive Functions by Cerebral Pulse Oximetry
General and Spinal Anesthesia can be used in geriatric patients in orthopedic surgery. Post-op cognitive dysfunction can be seen in orthopedic surgeries in this group of patients.
- Trial name
- NCT03827083
- Testing
- cerebral pulse oximetry
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tepecik Training and Research Hospital
Cerebral Palsy
Cognitive Functioning in Children and Adolescents With Cerebral Palsy
Background: Cerebral palsy (CP) is characterized by motor impairment but commonly involves more widespread difficulties, including cognitive impairment.
- Trial name
- CPCog-Youth-DK (NCT05921422)
- Testing
- Cognitive assessment
- Where
- 2 sites in Denmark
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Alzheimer's Disease
Safety and Effectiveness Study of Intranasal Insulin Glulisine on Cognitive and Memory in Mild-Mod AD Patients.
The purpose of this study is to investigate the effect of the rapidly acting intranasal insulin derivative (glulisine) on memory and cognition in 12 patients suffering from mild-moderate Alzheimer's Disease (AD) using a…
- Trial name
- NCT01436045
- Testing
- Insulin glulisine, Saline
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- HealthPartners Institute
Cognitive Change, Sleep Deprivation
Sleep Deprivation Study
The purpose of this study is to evaluate the measures of brain function, both neurophysiological (event-related potentials (ERPs) and functional (cognitive assessments), in response to sleep deprivation.
- Conditions
- Cognitive Change, Sleep Deprivation, Caffeine
- Trial name
- NCT05560620
- Testing
- Sleep Deprivation, Caffeine, No Caffeine
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- NeuroCatch Inc.
Memory Loss, Cognitive Changes
Aging and Estrogen on Cortical Function
This study will focus on how estrogen affects parts of the brain associated with memory and how the effect of estrogen is altered with aging in postmenopausal women.
- Conditions
- Memory Loss, Cognitive Changes, Postmenopausal Symptoms
- Trial name
- NCT01268046
- Testing
- Estradiol oral capsule, transderman estrogen patch
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Subjective Cognitive Decline
Β-OHB Supplementation and Brain Health in Older Adults
The goal of this randomized placebo controlled crossover trial is investigate the effects of short-term ketone monoester (KME) supplementation to brain function in older adults with subjective cognitive decline.
- Trial name
- NCT06588946
- Testing
- Ketone monoester (KME) supplement
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- McMaster University
Depressive Symptoms, Parkinson's Disease
Rasagiline in Cognitive-impairment Related Depression: AzileCt in COgnitive-impairment Related DepressiOn
The primary endpoint for this study is the clinical response after 12 weeks of treatment, defined as a change in total score from baseline depressive symptoms as measured by the Beck Depression Inventory-Amended (BDI-IA) total…
- Trial name
- ACCORDO (NCT01055379)
- Testing
- Rasagiline
- Where
- 12 sites in Italy
- Volunteers
- 121 people
- Sponsor
- Lundbeck Italia S.p.A.
PTSD, Cognitive Function
Self-regulation of Prefrontal Cortex During Emotional Cognitive Control in PTSD
Deficits in emotional cognitive control are present in a number of clinical psychiatric populations including depression, anxiety, and PTSD.
- Trial name
- SPrC-PTSD (NCT04543513)
- Testing
- Real-time functional magnetic resonance neurofeedback (rtfMRI-nf)
- Where
- United States
- Sponsor
- Laureate Institute for Brain Research, Inc.
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