Clinical trials: Functional Cognitive Disorder
Oral Health
A Study on the Correlation Between Oral Health and Delirium in Surgical Inpatients
Delirium is a clinical syndrome characterized by acute attention deficits, altered consciousness, and fluctuating cognitive dysfunction, typically triggered by multifactorial causes such as physical illness, medication use, or…
- Trial name
- NCT06969092
- Testing
- Oral Frailty
- Where
- China
- Volunteers
- 550 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Mild Cognitive Impairment
Comparison of High-Intensity Interval Training and Moderate-Intensity Continuous Training in Mild Cognitive Impairment
This study aims to determine the effects of High-Intensity Interval Training (HIIT) and Moderate-Intensity Continuous Training (MICT) on cognitive and physical fitness in community-dwelling adults diagnosed with Mild Cognitive…
- Trial name
- NCT07248709
- Testing
- High-Intensity Interval Training (HIIT), Moderate-Intensity Continuous Training
- Where
- 2 sites in Pakistan
- Volunteers
- 68 people
- Sponsor
- Riphah International University
Cognitive Assessment, Psychological Function
Snacks and Brain Health
This project will investigate whether daily snack consumption can improve memory, mood, and overall brain function in people with cognitive impairment.
- Conditions
- Cognitive Assessment, Psychological Function, GI Health
- Trial name
- NCT07348406
- Testing
- Pecan snack, Pretzel snack
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Texas Tech University Health Sciences Center
Atrial Fibrillation
EMOTIon and COgNitive Function After Atrial Fibrillation Catheter Ablation vs. Medical Therapy(EMOTICON Trial)
"Atrial fibrillation (AF) is an arrhythmic disease that increases especially in the elderly, increasing the risk of ischemic stroke by 5 times and is a major cause of dementia and cognitive impairment.
- Trial name
- NCT04942171
- Testing
- Atrial fibrillation catheter ablation group, Medical therapy group
- Where
- South Korea
- Volunteers
- 320 people
- Sponsor
- Yonsei University
Cognitive Disorders, HIV Infections
A Study of Decreased Mental Function Associated With HIV
The purpose of this study is to compare pictures of the brain of HIV-infected people with memory problems before and after treatment with selegiline. Selegiline is the study drug received through A5090.
- Trial name
- NCT00027040
- Testing
- Selegiline hydrochloride
- Where
- 12 sites in United States
- Volunteers
- 90 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Metabolic Syndrome, Coronary Heart Disease
Cognition and Exercise Training
The aim of study is to investigate the impact of two different training modalities (high intensity interval training (HIIT) versus moderate intensity continuous exercise training (MICET) on cognitive performance, cerebral…
- Conditions
- Metabolic Syndrome, Coronary Heart Disease, Chronic Heart Failure
- Trial name
- COGNEX-2 (NCT01906957)
- Testing
- high intensity interval training (HIIT), moderate intensity continuous exercise training
- Where
- 2 sites in Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Montreal Heart Institute
Intellectual Disability
Therapy-Based Games' Effects on Motor and Cognitive Skills in Intellectual Disabilities
Individuals with intellectual disabilities face challenges in areas of attention, motor skills, and awareness. Among the problems they experience are difficulties in focusing, transitioning from one activity to another…
- Trial name
- NCT06097819
- Testing
- Mobile app-based game group, Supervised combined sensor-based game group, Individualized occupational therapy group
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Istanbul Medipol University Hospital
Mild Cognitive Impairment
EXCEL: Exercise for Cognition and Everyday Living for Seniors With Memory Complaints
Alzheimer's disease (AD) is a major health issue in Canada; it affects over 8% of the population aged over 65 years. Persons with AD have a reduced quality of life as they become dependent on others for activities of daily living…
- Trial name
- NCT00958867
- Testing
- Exercise program (AT), Exercise training (RT), Exercise training (S & R; control)
- Where
- Canada
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Healthy
Efficacy, Transfer, and Neuro-functional Basis of a Memory Training Targeting Episodic Retrieval in Older Adults.
Aging leads to cognitive changes that affect memory, particularly episodic retrieval. These impairments are detrimental to seniors' quality of life.
- Trial name
- SPECTRA (NCT06110234)
- Testing
- Episodic Specificity Induction, Associative Memory
- Where
- Canada
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal
Acquired Brain Injury
Exploring the Use of the Cognitive Orientation to Daily Occupational Performance Approach (CO-OP) With Children, Teenagers and Young Adults With Executive Functions Deficits Following Severe Acquired Brain Injury
Acquired brain injury (ABI) in childhood are the cause of disabling motor, cognitive and behavioural disorders, with severe consequences on the later development of autonomy and learning, with long-term repercussions on…
- Trial name
- REFECO-OP (NCT04560777)
- Testing
- CO-OP intervention
- Where
- 2 sites in France
- Volunteers
- 12 people
- Sponsor
- Hopitaux de Saint-Maurice
Parkinson Disease (PD)
Pilot Deprescribing of Antimuscarinic Overactive Bladder Medications in Parkinson Disease
This is an unblinded, non-randomized National Institute of Health (NIH) Stage I of Behavioral Intervention Development trial. The investigators will enroll 20 subjects with Parkinson disease (PD) for a series of 20 of N-of-1…
- Trial name
- NCT07627529
- Testing
- Overactive bladder antimuscarinic deprescribing
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Corporal Michael J. Crescenz VA Medical Center
Schizophrenic Disorder, Cognitive Impairment
Sodium Butyrate For Improving Cognitive Function In Schizophrenia
The purpose of this grant is to evaluate the efficacy of sodium butyrate as a novel treatment for cognitive deficits in schizophrenia (SZ).
- Trial name
- NCT03010865
- Testing
- Sodium Butyrate
- Where
- China
- Sponsor
- Shanghai Mental Health Center
Glioma, Brain Neoplasm
EEG-Guided Cognitive Function Preservation in Patients With Brain Tumors
Brain tumors and their surgical treatment may impair cognitive function, affecting patients' quality of life. This prospective single-arm study aims to evaluate the feasibility and clinical utility of an EEG-based neural signal…
- Conditions
- Glioma, Brain Neoplasm, Brain Tumor Adult
- Trial name
- NCT07699172
- Testing
- EEG-Based Neural Signal Decoding Strategy
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Bo Wang
Epilepsy, Autism Spectrum Disorder
Biomarkers for Epilepsy Development and the Effect of Physical Exercise in Children With Autism
This study aims to identify novel biomarkers for epilepsy development in children with autism and to evaluate the effects of physical exercise on these biomarkers and clinical outcomes.
- Trial name
- ASD/EP (NCT07373431)
- Testing
- Physical activity program
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Region Skane
Cognitive Impairment, High Fall Risk
Fall Prevention in Mild Cognitive Impairment
Falls represent the leading cause of hospitalization, nursing home admissions, disability and mortality for older adults with annual healthcare costs over $50 billion.
- Trial name
- NEUROFALL (NCT07507812)
- Testing
- Virtual Neurophysiological Rehabilitation
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- VA Office of Research and Development
ADHD
A Novel fNIRS Neurofeedback Intervention for Enhancement of Working Memory in Attention Deficit Hyperactivity Disorder (ADHD)
The proposed study is to test and validate a novel intervention that integrates computerized cognitive training with real-time neuromonitoring and neurofeedback to enhance working memory by probing the individualized neural…
- Trial name
- NCT04002167
- Testing
- Neurofeedback, Cognitive training
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Stanford University
Attention Deficit Hyperactivity Disorder
Efficacy of Cognitive Behavioral Therapy in Treatment of Adults With Attention Deficit Hyperactivity Disorder
The purpose of the project is to evaluate the efficacy of cognitive behavioral therapy (CBT) for adults with attention deficit hyperactivity disorder (ADHD) with and without stimulant medication and compare it to medication…
- Trial name
- NCT02210728
- Testing
- methylphenidate or amphetamine product, Cognitive behavioral therapy
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Lily Hechtman
Alzheimer's Disease, Huntington's Disease
A Phase 1, Non-Randomized, Open-Label, Single-Dose Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [PF 01913539] In Subjects With Severely-Impaired And Normal Renal Function
This study is to compare the pharmacokinetics of Dimebon in subjects with severe renal impairment to subjects with normal renal function after oral administration of a single oral 20-mg dose of Dimebon.
- Trial name
- NCT00824590
- Testing
- Dimebon
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pfizer
Age-related Functional Decline, Mild Cognitive Impairment
Health Benefits of Nutraceutical Supplementation in Older Adults.
This study examines a multi-ingredient nutraceutical designed to support several areas of health in older adults, including muscle strength, cognitive function, immune response, and inflammation.
- Trial name
- NCT07534878
- Testing
- Powder containing whey isolate and herbal extracts (30g sachet)
- Where
- India
- Volunteers
- 23 people
- Sponsor
- GPLIFE HEALTHCARE PRIVATE LIMITED
Energy Restriction, Sleep Deprivation
Brain Energy and Cognition
This proposed laboratory study will extend previous findings on relationships between cognitive function and nutritional status to conditions that more closely resemble military operations where aerobic exercise, inadequate…
- Trial name
- NCT01603550
- Testing
- Sleep Deprivation, Energy Restriction
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.