Clinical trials: Functional Cognitive Disorder
Multiple Sclerosis
Effects of Lutein Supplementation on Cognition and MPOD in Multiple Sclerosis Patients-
The central hypothesis is that lutein supplementation will improve MPOD and cognition. Accordingly, the specific aims are to 1) to determine the process feasibility associated with participating in 4-month lutein supplementation…
- Trial name
- LuMES (NCT04843813)
- Testing
- Lutein
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Illinois at Urbana-Champaign
Mild Cognitive Impairment
Effect of Tablet-Based Games on Executive Functions in Older Adults With Mild Cognitive Impairment
The primary objective of this study is to investigate whether a tablet-based role-playing game is more effective than tablet-based word or image puzzles at improving executive functions in older adults with mild cognitive…
- Trial name
- NCT05468424
- Testing
- tablet (iPad or android) based role-playing game, tablet (iPad or android) based word puzzles and image puzzles
- Where
- 2 sites in Canada
- Volunteers
- 42 people
- Sponsor
- John Puxty
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
The Effect of Acupuncture Therapy on Cognitive Function in Post-COVID-19 Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Background of study: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a common sequela after SARS-CoV-2 infection(COVID-19). Cognitive dysfunction is one of the most common debilitating symptoms in ME/CFS.
- Trial name
- NCT07357688
- Testing
- Acupuncture
- Where
- 2 sites in China
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Xi Wu
Chronic Low-back Pain
Cognitive Functional Therapy Compared With Sham-treatment for Low Back Pain
Chronic low back pain is a public health problem, and there is strong evidence that it is associated with a complex interaction of biopsychosocial factors.
- Trial name
- NCT04518891
- Testing
- Cognitive Functional Therapy (CFT)
- Where
- Brazil
- Volunteers
- 152 people
- Sponsor
- University of Sao Paulo
Breast Cancer, Cancer Survivor
Cognitive Enhancement Program in Improving Cognitive Function in Breast Cancer Survivors
This randomized clinical trial studies cognitive enhancement program in improving cognitive function in breast cancer survivors.
- Conditions
- Breast Cancer, Cancer Survivor, Cognitive/Functional Effects
- Trial name
- NCT02166983
- Testing
- computer-assisted cognitive training, cognitive intervention, mind-body intervention procedure
- Where
- United States
- Sponsor
- Stanford University
Cognitive Impairment, Cognitive Function
Brain Health in Breast Cancer Survivors
Endocrine therapy (ET) is widely used to treat hormone receptor positive breast cancer and prevent recurrence by downregulating estrogen function.
- Trial name
- NCT04297020
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Jonsson Comprehensive Cancer Center
Balance Disorders, Accidental Falls
Population Cohort Set-up for the Epidemiological Assessment of Balance Disorders in Elderly People
As people age, it becomes more common to experience balance problems. These issues can increase the risk of falling, which may lead to serious health consequences and loss of independence.
- Conditions
- Balance Disorders, Accidental Falls, Frailty, Aging
- Trial name
- EPIBAS (NCT06965660)
- Where
- Spain
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Alzheimer Disease, Functional Food
Non-pharmacological Intervention for Preclinical Alzheimer's Disease
Alzheimer's disease (AD) is the most common form of neurodegenerative disorders leading to dementia. Currently, there has been no effective drugs targeting this disease.
- Conditions
- Alzheimer Disease, Functional Food, Subjective Cognitive Decline, Intervention
- Trial name
- NCT04279418
- Testing
- Mixed functional foods supplementation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- XuanwuH 2
Strength Training Adaptations, Stress
The Impact of 12-week Ashwagandha Supplementation Induced by Resistance Training on Strength, Levels of Neurotrophic and Stress Response Proteins, Oxidative and Psychological Stress, and Cognitive Function in Physically Active Male Adults
This clinical trial will study the effects of Ashwagandha (Withania somnifera), a natural plant extract, on physical and mental health in adult men.
- Conditions
- Strength Training Adaptations, Stress, Sleep Quality, Cognitive Functions
- Trial name
- NCT07803068
- Testing
- Ashwagandha, Resistance training
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Fibromyalgia
Kinesthetic Brain and Telerehab Pilates for Cognitive and Functional Outcomes in Women With Fibromyalgia
Fibromyalgia is a chronic pain syndrome often accompanied by fatigue, psychological problems, and cognitive dysfunction, leading to reduced quality of life.
- Trial name
- NCT07141550
- Testing
- Clinical Pilates Group, Kinesthetic Brain Exercises Group
- Volunteers
- 30 people
- Sponsor
- Izmir Democracy University
Insomnia, Alzheimer Disease
Transdermal Trigeminal Electrical Neuromodulation on Mild Cognitive Impairment With Insomnia
This study aims to validate the safety and impact of transdermal trigeminal electrical neuromodulation(Cefaly) on mild cognitive impairment patients with insomnia on brain functional and structural connectivity as well as sleep…
- Conditions
- Insomnia, Alzheimer Disease, Mild Cognitive Impairment, Amyloid
- Trial name
- NCT05200897
- Testing
- Transdermal trigeminal electrical neuromodulation(Cefaly)
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Saint Vincent's Hospital, Korea
Obesity, Adolescent
Increased Protein at Breakfast for Weight Management in Overweight Adolescents
Adolescent obesity, negatively affecting the lives of over 18 million (34%) US adolescents, continues to be a major public health concern due to the increased risk of developing chronic diseases, including type 2 diabetes.
- Trial name
- NCT03146442
- Testing
- Breakfast
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Overactive Bladder, Mild Cognitive Impairment
A Study of Fesoterodine and Oxybutynin on Cognitive Function in Mild Cognitive Impairment
The purpose of this study is to assess the effects of fesoterodine at 4mg and 8mg doses versus a placebo and oxybutynin 5mg bid versus placebo on cognitive abilities in older people with overactive bladder and mild cognitive…
- Trial name
- NCT02240459
- Testing
- fesoterodine 4mg, Oxybutynin, fesoterodine 8mg
- Where
- Canada
- Volunteers
- 47 people
- Sponsor
- University of Alberta
Schizophrenia
Effects of 12 Weeks Walking on Cognitive Function in Schizophrenia
This study is a 12-week randomized-controlled clinical trial. It will be planned to conduct in a total of 120 male and female subjects from the Department of Psychiatry at Kaohsiung Chang Gung Memorial Hospital.
- Trial name
- NCT04411979
- Testing
- treatment-as-usual plus aerobic walking
- Where
- Taiwan
- Volunteers
- 85 people
- Sponsor
- Chang Gung Memorial Hospital
Multiple Sclerosis
Aerobic Training Effects on Motor and Cognitive Performances in MS: an Exploratory Study With Structural and Functional MRI
Aerobic training (AT) induces cardiovascular, metabolic and muscular changes and has been proposed as a promising rehabilitative approach in elderly adults and in neurological patients to improve both motor and cognitive…
- Trial name
- NCT04097418
- Testing
- Aerobic training compared to conventional motor training
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Leukemia, Lymphoma
Improving Cognitive Function in Older Adults Undergoing Stem Cell Transplant
Cancer and treatment-related cognitive changes, such as thinking or remembering, hinder resumption of normal routine and roles and worsen quality of life.
- Conditions
- Leukemia, Lymphoma, Multiple Myeloma, Myelodysplastic Syndromes (MDS)
- Trial name
- PROACTIVE (NCT04898790)
- Testing
- CHAMPS-II adapted to adults 60+ years in HCT setting
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- University of Nebraska
Insomnia
Playing Cognitive Games For Older Adults With Insomnia
The purpose of this research is to look at the effects of computerized cognitive training on sleep, mental abilities (cognition), and other aspects of daytime functioning, such as mood, and arousal
- Trial name
- PLAY (NCT04282642)
- Testing
- Cognitive Training, WLC (Waitlist Control)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Cognitive Impairment
Turkish Version of the Cognitive Functioning Self-Assessment Scale
Self-report scales used in the assessment of cognitive functions can serve as an initial screening tool for the general population, aside from specific neuropsychiatric tests, which are more costly and time-consuming.
- Trial name
- NCT06678412
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Chronic Kidney Failure, Renal Dialysis
Health Related Quality of Life and Cognitive Function Among Norwegian Dialysis Patients
The purpose of this study is to assess health related quality of life and its predictors among chronic dialysis patients and to assess cognitive function using 3 different tests.
- Trial name
- NCT00806130
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Norwegian University of Science and Technology
Cognitive Impairment
An fMRI Study of Jianpi Yishen Huatan Granules for Cognitive Impairment After Acute Cerebral Infarction
The purpose of this study is to explore the pathogenesis of cognitive impairment after acute cerebral infarction by applying the multimodal function MRI to dynamically observe the changes of the value of NAA,Cho,Cr,FA in a…
- Trial name
- NCT02752867
- Testing
- Jianpi Yishen Huatan Granules
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Dongfang Hospital Beijing University of Chinese Medicine
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