Clinical trials: Functional Cognitive Disorder
Cognitive Dysfunction, Cognitive Decline
Broccoli Sprout Extract for Cognitive Function
This clinical trial aims to determine whether broccoli sprout extract improves cognitive function in adults with mild cognitive impairment and to assess its safety.
- Trial name
- NCT07334366
- Testing
- Broccoli sprout extract (BSE)
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Pusan National University Yangsan Hospital
ADHD - Attention Deficit Disorder With Hyperactivity
Brain Stimulation and Attention Control in Children With ADHD
The goal of this clinical trial is to learn if brain stimulation can help children ages 6 to 12 with attention-deficit/hyperactivity disorder (ADHD) improve their attention and self-control.
- Trial name
- NCT07182344
- Testing
- Intermittent Theta Burst Stimulation to Right DLPFC
- Where
- 2 sites in Kazakhstan
- Volunteers
- 40 people
- Sponsor
- Neurolab Plus
Type1diabetes
Effects of Ketosis on Brain Function in Patients With T1DM
The scientific goal of this study is to examine the effects of a ketogenic diet on hypoglycemia tolerance and brain function in people with type 1 diabetes mellitus (T1D) and to clarify the mechanistic role of ketones in this…
- Trial name
- NCT04219709
- Testing
- Very low carbohydrate diet, Standard carbohydrate diet
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Boston Children's Hospital
Schizophrenia
Evaluating Two Types of Cognitive Training in Veterans With Schizophrenia
Cognitive dysfunction is a major contributor to the poor community outcome of individuals with schizophrenia. Developing more effective cognitive remediation interventions is imperative to improve the daily lives of affected…
- Trial name
- NCT01891721
- Testing
- Brain Fitness Program (BFP), Cognitive Package (Cogpack), Commercial Computer Games (Sporcle)
- Where
- 2 sites in United States
- Volunteers
- 105 people
- Sponsor
- VA Office of Research and Development
Rett Syndrome
Cognitive Function in Rett Syndrome During Trofinetide Treatment
Assessing cognitive functions among individuals with severe intellectual and developmental disabilities (IDD), including RTT, is often challenging due to floor effects of many standardized assessment batteries in this population.
- Trial name
- NCT06705816
- Testing
- None interventional
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Minnesota
Migraine Headache, Cognitive Impairment
Treximet in Acute Migraine Headache: Assessing Cognitive Function
Migraine headache occurs frequently in women more than men and is associated with symptoms not only of significant pain but also of symptoms typically including of photophobia, phonophobia, nausea and vomiting.
- Trial name
- NCT00837044
- Testing
- Treximet, Migraine rescue medication of choice
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Neurological Research Center
Acquired Brain Injury
Virtual Reality vs Traditional Cognitive Training in Patients With Severe Acquired Brain Injury
Considerable evidence exists for using Virtual Reality (VR) for rehabilitation of acquired brain injury (ABI), with a particular focus on stroke.
- Trial name
- VR-sABI (NCT06474871)
- Testing
- Khymeia®-Virtual Reality rehabilitation System (VRRS EVO SYSTEM or COMPACT VRRS ENGINE), Traditional cognitive training (TCT)
- Where
- 5 sites in Italy
- Volunteers
- 28 people
- Sponsor
- Anna Estraneo
Brain Metastases, Adult, Neurocognitive Function
UCSD Image-Guided Cognitive-Sparing Radiosurgery for Intracranial Lesions
In this proposal, the investigators introduce advanced diffusion and volumetric imaging techniques along with innovative, automated image parcellation methods to identify critical brain regions, incorporate into cognitive-sparing…
- Conditions
- Brain Metastases, Adult, Neurocognitive Function, Cancer, Meningioma of Brain
- Trial name
- IG-SRS (NCT04343157)
- Testing
- Cognitive Sparing Brain Stereotactic Radiosurgery (SRS)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Jona Hattangadi-Gluth
Frailty, Disability Physical
Prevention of Functional and Cognitive Impairment Through a Multicomponent Exercise Program
The hospitalized elderly patient is conditioned by a series of circumstances unrelated to the pathological process itself that caused hospital admission and that usually worsen the results of hospitalization.
- Conditions
- Frailty, Disability Physical, Hospital Acquired Condition
- Trial name
- NCT04600453
- Testing
- Physical Exercise
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Fundacion Miguel Servet
Down Syndrome
Non-drug Study to Evaluate the Suitability of Neurocognitive Tests and Functioning Scales for the Measurement of Cognitive and Functioning Changes in Children With Down Syndrome
The aim of this study is to assess the suitability of selected scales (floor/ceiling effects, variability, test-retest reliability) to measure cognitive function in children with Down syndrome over 6 months, and to evaluate the…
- Trial name
- NCT02451657
- Testing
- No Intervention
- Where
- 10 sites in United States, France and 1 more
- Volunteers
- 40 people
- Sponsor
- Hoffmann-La Roche
Chronic Insomnia Disorder
Modified Suanzaoren Decoction Versus Eszopiclone for the Treatment of Chronic Insomnia Disorder
The purpose of this study is to observe the cognitive function and clinical efficacy of modified Suanzaoren decoction and eszopiclone in the treatment of chronic insomnia disorder patients, and to investigate the possible neural…
- Trial name
- NCT06452953
- Testing
- suanzaoren decoction, Eszopiclone 1 mg
- Where
- China
- Volunteers
- 85 people
- Sponsor
- Central South University
Mild Cognitive Impairment
Investigating Mild Cognitive Impairment in Patients And Controls With TD-fNIRS
The goal of the proposed observational, multi-site study is to use fNIRS neurophysiological data recorded during a battery of tasks to detect MCI within a cohort consisting of patients and age-matched healthy controls.
- Trial name
- IMPACT (NCT05996575)
- Testing
- fNIRS measurement
- Where
- 6 sites in United States
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Kernel
Stroke
Tele-Rehabilitation Study for People With a History of Stroke
Stroke results in long-term disability for many people, and particularly for survivors of stroke who have cognitive impairments.
- Trial name
- NCT02724813
- Testing
- Cognitive Orientation to Occupational Preformance (COOP)
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Baycrest
Mild Cognitive Impairment
Efficacy of Different Doses of Tai Chi Chuan on Cognitive Function in Persons With Mild Cognitive Impairment
To determine the relationship between the effects of different frequencies and duration of Tai Chi Chuan in dose parameters to improve cognitive function in elderly persons with mild cognitive impairment.
- Trial name
- NCT06375720
- Testing
- Lower frequency, shorter period of Tai Chi Chuan, Higher frequency, shorter period of Tai Chi Chuan, Lower frequency, longer period of Tai Chi Chuan
- Volunteers
- 350 people
- Sponsor
- Lidian Chen
Physician Well-being, Cognitive Function
Performance Nutrition for Residents and Fellows
Currently, residents commonly experience dehydration and poor nutrition during nighttime duty hours as a result of heavy work load, lack of time to take nutrition and hydration breaks, or limited or no access to healthy food and…
- Conditions
- Physician Well-being, Cognitive Function, Diet Modification, Diet Habit
- Trial name
- NCT03698123
- Testing
- Dietary Modification
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Stanford University
Hypoglycaemia
Recurrent Hypoglycaemia in Type 1 Diabetes
Patients with type 1 diabetes are at risk of very low blood sugar levels (hypoglycaemia) as a severe side effect to insulin therapy, in particular subjects who have lost warning of hypoglycaemia.
- Trial name
- HypoNeuro (NCT01337362)
- Testing
- Insulin clamp
- Where
- Denmark
- Volunteers
- 23 people
- Sponsor
- Hillerod Hospital, Denmark
Insomnia
Playing Cognitive Games For Older Adults With Insomnia
The purpose of this research is to look at the effects of computerized cognitive training on sleep, mental abilities (cognition), and other aspects of daytime functioning, such as mood, and arousal
- Trial name
- PLAY (NCT04282642)
- Testing
- Cognitive Training, WLC (Waitlist Control)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Cognitive Manifestations
Asymptomatic Carotid Stenosis: Cognitive Function and Plaque Correlates
Carotid artery plaques are known to cause stroke. Cognitive impairment is an insidious but poorly understood problem in patients with carotid plaques.
- Trial name
- ACCOF (NCT01353196)
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- VA Office of Research and Development
Mild Cognitive Impairment, Healthy Controls
Cross-Cultural Use of Performance-Based Functional Assessment in Alzheimer's Disease
This study plans to assess the effectiveness of performance-based functional assessments (PBFAs) and cognitive assessments in diagnosing Alzheimer's disease in Hispanic/Latino populations.
- Trial name
- NCT03081546
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Thalassemia, Brain Function (Measured by ERP Level)
A Case Control Study to Evaluate the Cognitive and Brain Function of β-thalassemia Patients.
β-thalassemia syndromes are a group of hereditary disorders characterized by a genetic deficiency in the synthesis of beta-globin chains.
- Trial name
- NCT01935661
- Where
- Israel
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
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