Clinical trials: Functional Cognitive Disorder
Major Depression
My Depression Wellness Toolkit Study
Major depressive disorder (MDD) continues to have a profound impact on individuals, families, and the health care system. Despite marked success in treating active individual episodes of unipolar depression, our understanding of…
- Trial name
- NCT01178424
- Testing
- Mindfulness Based Cognitive Therapy, Cognitive Behaviour Therapy
- Where
- Canada
- Volunteers
- 166 people
- Sponsor
- Centre for Addiction and Mental Health
Consciousness Disorder, Cognitive Impairment
Neurophysiological Evaluation of Residual Cognitive Functions in Patients With Severe Alterations of Consciousness
Identify potential markers of recovery through event-related potentials (ERPs) in the evolution of altered consciousness with potential ability to discriminate between different conditions of altered state of consciousness.
- Trial name
- NCT05802524
- Testing
- Neurowave Group
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Ischemic Stroke, Hemorrhagic Stroke
Transcranial Direct Current Stimulation, Functional Activity, Stroke, RCT
Stroke patients often experience impaired balance and weight-bearing due to muscle weakness and neurological deficits. Motor rehabilitation is a crucial goal in their recovery, and transcranial direct current stimulation (tDCS)…
- Conditions
- Ischemic Stroke, Hemorrhagic Stroke, Stroke, Cardiovascular
- Trial name
- NCT07200661
- Testing
- Experimental A tDCS: Transcranial direct current stimulation., Experimental B tDCS: Transcranial direct current stimulation., Experimental C tDCS: Transcranial direct current stimulation.
- Where
- 3 sites in Thailand
- Volunteers
- 30 people
- Sponsor
- University of Phayao
Multiple Sclerosis
The Effect of Internal- or External-Focused Exercise Training, Administered in Conjunction With a Cognitive Task, on Walking, Balance, and Cognitive Functions in Individuals With Multiple Sclerosis
This interventional clinical trial aims to investigate the effects of internal and external focus-based exercise training combined with cognitive dual-task training in individuals diagnosed with multiple sclerosis.
- Trial name
- NCT07507084
- Testing
- Internal Focus Dual-Task Training, External Focus Dual-Task Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Kutahya Health Sciences University
Schizophrenia Disorders, Cognitive Dysfunction
Cognitive Remediation Therapy for Schizophrenia: Effects on EEG and Emotional Regulation
This study aims to determine whether Cognitive Remediation Therapy (CRT) can improve attention, memory, and emotional regulation in people with schizophrenia.
- Conditions
- Schizophrenia Disorders, Cognitive Dysfunction, Emotion Regulation Disorders
- Trial name
- CRT-SCHZ (NCT06936397)
- Testing
- Cognitive Remediation Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Beykoz University
Multiple Sclerosis
Home-based EXergames To impRove cognitivE Function in MUltiple Sclerosis
Study design: Phase II, multicenter, randomized, sham-controlled, single-blind, parallel arm, multicenter study to test the hypothesis that home-based exergames is not inferior to home-based cognitive rehabilitation delivered by…
- Trial name
- EXTREMUS (NCT04169750)
- Testing
- Exergames, Adaptive COGNI-TRAcK
- Where
- 4 sites in Italy
- Volunteers
- 135 people
- Sponsor
- San Camillo Hospital, Rome
Carpal Tunnel Syndrome
Effects of Mirror Therapy on Pain and Function on Bilateral Carpal Tunnel Syndrom
The purpose of this study was to evaluate pain and function after mirror therapy as well as level of catastrophism in bilateral carpal tunnel syndrome patients
- Trial name
- MTSTC (NCT03169218)
- Testing
- Mirror therapy
- Where
- Spain
- Volunteers
- 18 people
- Sponsor
- Olga Del Pozo Blanco
Mild Cognitive Impairment, Mild Dementia
Resistance Training to Individuals for Cognitive Impairment With Dementia
This research project aims to analyze the effects of different resistance training volumes on cognitive function, oxidative stress, immunological response, lipid profile, glycemic status, liver function, muscle function…
- Trial name
- TRAIN4BRAIN (NCT06185010)
- Testing
- One Resistance Training Set (Single Session), Three Resistance Training Sets (Single Session), One Resistance Training Set (8 Weeks)
- Where
- Portugal
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Beira Interior
Stroke, Acute
Health Disparities in Stroke Patients and Their Families: a Longitudinal Multicenter Study (HDSS)
The meeting point of the patient and his/her immediate family with the health care system is complicated and traumatic. While having to deal with medicalization geared towards providing evidence-based and cost-effective medical…
- Trial name
- HDSS (NCT03330652)
- Where
- 4 sites in Israel
- Volunteers
- 600 people
- Sponsor
- Sheba Medical Center
Lymphoma
PET-based Evaluation of Chemotherapy-induced Brain Damage in Lymphoma
Positron emission tomography (PET) with 18-fluoro-deoxy-glucose (PET-FDG) is emerging as a promising approach for detecting brain lesions in dementia, among which Alzheimer's disease has been the most widely studied.
- Trial name
- LYMCOTEP (NCT02601547)
- Testing
- PET-FDG brain imaging and NPT
- Where
- France
- Volunteers
- 18 people
- Sponsor
- University Hospital, Toulouse
Postoperative Cognitive Dysfunction
Effect of Ciprofol Injection on Postoperative Cognitive Function
This study aims to explore the effect of ciprofol on the postoperative cognitive function of inpatients undergoing gastrointestinal endoscopy examination, to compare the anesthetic effects and differences in adverse reactions of…
- Trial name
- NCT07673978
- Testing
- Ciprofol group, Propofol group
- Where
- China
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Postoperative Cognitive Dysfunction
Evaluation of the Effect of Preoperative Intravenous Amantadine Sulfate on the Postoperative Early Cognitive Functions in a Elderly Patient With Laparoscopic Radical Prostatectomy
Evaluation of the effect of preoperative intravenous administration of amantadine sulfate on the prevention of the development of early cognitive dysfunction in elderly patients undergoing laparoscopic radical prostatectomy
- Trial name
- NCT03988010
- Testing
- Amantadine Sulfate
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- TC Erciyes University
Multiple Sclerosis
Effects of tDCS and Cognitive Rehabilitation on Cognition and Neural Plasticity in MS Patients
The goal of this clinical trial is to evaluate whether transcranial direct current stimulation (tDCS) and cognitive rehabilitation can improve cognitive functions and neuronal plasticity in patients with multiple sclerosis (MS).
- Trial name
- NCT07160218
- Testing
- tDCS, Cognitive Rehabilitation
- Where
- Iran
- Volunteers
- 45 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Fronto-temporal Dementia, Fronto-temporal Lobar Dementia
Vortioxetine for the Treatment of Mood and Cognitive Symptoms in Frontotemporal Dementia
The goal of this clinical trial is to learn if vortioxetine improves mood symptoms and cognition in patients with early-stage behavioral variant Frontotemporal Dementia (bvFTD).
- Conditions
- Fronto-temporal Dementia, Fronto-temporal Lobar Dementia, Frontotemporal Degeneration, Frontotemporal Dementia (FTD)
- Trial name
- NCT06604520
- Testing
- Vortioxetine
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Primary Brain Tumor, Neurocognition
Executive and Socio-cognitive Functions in Survivors of Primary Brain Tumor: Impact on Patients' Quality of Life
Significant advances in primary malignant brain tumors (PBT) treatment have led to dramatically improved survival, both in children and adults.
- Conditions
- Primary Brain Tumor, Neurocognition, Quality of Life
- Trial name
- NEUROCOG-QOL (NCT02693405)
- Testing
- Executive functions, social cognition, quality of life
- Where
- France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Alzheimer's Disease
The Effect of Cognitive Function as Measured by Repeated Cognitive Measures After 12 Weeks Treatment With Donepezil
The purpose of this study is to determine if there is improvement or measurable change in cognition after only one month of treatment with donepezil when using a computerized test battery.
- Trial name
- NCT01024660
- Testing
- Donepezil
- Where
- 18 sites in Canada, Peru and 2 more
- Volunteers
- 155 people
- Sponsor
- AstraZeneca
Age-related Cognitive Decline
ItaliaN Study With Tailored Multidomain Interventions to Prevent Functional and Cognitive Decline in Community-dwelling Older Adults
The goal of this interventional non-pharmacological study is to investigate the effects of a multi-domain intervention ( "active intervention"), compared to that followed by normal clinical practice ("self-guided intervention")…
- Trial name
- IN TeMPO (NCT06248723)
- Testing
- Nutritional intervention, Physical exercise, Cognitive training
- Where
- Italy
- Volunteers
- 1,340 people, healthy volunteers welcome
- Sponsor
- University of Milano Bicocca
Healthy
Efficacy of Multiple Micronutrient Fortified Biscuits and Deworming in Vietnamese School Children
The aim of this study is to identify the effect of a school-based food fortification intervention with multi-micronutrients with or without deworming to improve anemia, micronutrient status, cognitive function, health (morbidity…
- Trial name
- NCT00728273
- Testing
- worm treatment and multiple micronutrient fortified biscuits
- Where
- Thailand
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- Neys-van Hoogstraten Foundation, The Netherlands
Attention Deficit Hyperactivity Disorder
Neuroendocrine Substrates, Candidate Genes and Endophenotypes in ADHD
Attention-deficit/hyperactivity disorder (ADHD) is one of the most common child and adolescent psychiatric disorders. In recent years, some researchers have become interested in analyzing neuroendocrine substrate levels in ADHD…
- Trial name
- NCT02392169
- Testing
- Methylphenidate
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- Chang Gung Memorial Hospital
Chronic Kidney Disease
Exercise Trial in Chronic Kidney Disease
Chronic Kidney Disease (CKD) is exceedingly common in older adults, in whom it is associated with impairment in cognition and physical function.
- Trial name
- AWARD (NCT01462097)
- Testing
- Aerobic exercise training, Health Education
- Where
- 2 sites in United States
- Volunteers
- 99 people
- Sponsor
- University of Maryland, Baltimore
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