Clinical trials: Functional Colonic Disease
Central Nervous System Sensitization
Correlation Between Central Sensitization Inventory and Posturographic Data
To investigate the use of balance as a screening tool for Central Sensitization, a condition of the nervous system that is associated with the development and maintenance of chronic pain.
- Trial name
- NCT03058003
- Testing
- Posturography Evaluation, Central Sensitization Inventory
- Where
- 2 sites in United States, Australia
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Caps Research Network
Irritable Bowel Syndrome (IBS), Functional Dyspepsia
Interactive Effects of Early-Life Stress, Diet, and Metabolism on Gastrointestinal Dysfunction With Neuropsychiatric Symptoms
The goal of this observational case-control study is to learn how stressful experiences, dietary habits, and blood nutrient levels are associated with gastrointestinal symptoms and symptoms of depression and anxiety in adults…
- Conditions
- Irritable Bowel Syndrome (IBS), Functional Dyspepsia, Inflammatory Bowel Disease (IBD), Gastroparesis
- Trial name
- NCT07852819
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Shandong University
Fibromyalgia, Irritable Bowel Syndrome
Clinical Study on Implicit Learning, Comorbidity and Stress Vulnerability in Chronic Functional Pain
The project investigates on the role of pain avoidance, comorbidity and stress response for the development of chronic somatic and visceral pain.
- Trial name
- NCT00222209
- Testing
- Experimental heat pain model
- Where
- Germany
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Universitätsmedizin Mannheim
Irritable Bowel Syndrome
Fecal Microbial Transplantation in Treatment of Irritable Bowel Syndrome; a Double Blinded Placebo Controlled Trial.
Fecal Microbial Transplantation in Treatment of Irritable Bowel Syndrome; a Double Blinded Placebo Controlled Trial - the REFIT project Irritable bowel syndrome (IBS) is a condition characterized by variable complaints like…
- Trial name
- REFIT (NCT02154867)
- Testing
- Fecal transplantation
- Where
- Norway
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Abdominal Pain, Irritable Bowel Syndrome
Pain Processing and Pain Neuroscience Education in Children With Chronic Abdominal Pain
The primary scientific objective of the study entails examining whether altered endogenous pain inhibition is present in children with functional abdominal pain (FAP) and irritable bowel syndrome (IBS) compared with healthy…
- Trial name
- NCT02880332
- Testing
- Usual care, Pain Neuroscience education, Extra care
- Where
- Belgium
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Fibromyalgia, Irritable Bowel Syndrome
Welfare Benefits in Functional Somatic Disorders
The objective of this observational study is to estimate the number of weeks of welfare benefits, i.e. sickness benefit, unemployment benefit and social assistance, for individuals with functional somatic disorders and compare…
- Conditions
- Fibromyalgia, Irritable Bowel Syndrome, Chronic Fatigue Syndrome, Bodily Distress Syndrome
- Trial name
- NCT05611606
- Volunteers
- 9,656 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Irritable Bowel Syndrome, Food Sensitivity
Confocal Laser Endomicroscopy to Determine Influence of Food Antigens on Mucosal Integrity
Irritable bowel syndrome (IBS) is mainly associated with food intolerance and presents a particular challenge in gastrointestinal practice.
- Conditions
- Irritable Bowel Syndrome, Food Sensitivity, Healthy Controls
- Trial name
- RDS_CLE (NCT05056610)
- Testing
- food antigens on duodenal mucosa
- Where
- Germany
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Irritable Bowel Syndrome With Diarrhea, Irritable Bowel Syndrome
Safety and Efficacy of a Probiotic Supplement in IBS-D
This study aims to assess the safety and efficacy of a single probiotic strain on symptom severity in adults with diarrhea-predominant Irritable Bowel Syndrome (IBS-D).
- Trial name
- IBIS (NCT05754177)
- Testing
- Probiotic
- Where
- Slovenia
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- The Archer-Daniels-Midland Company
Irritable Bowel Syndrome (IBS)
Diet and Motility in IBS
The goal of this observational study is to identify factors that influence symptoms in children with irritable bowel syndrome (IBS), to find ways to make diet treatments work better and possibly create personalized plans to help…
- Trial name
- IBS (NCT07283341)
- Testing
- Wireless Patch System
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Irritable Bowel Syndrome
An Open-Label Study of Two Formulations of LX1033 in Healthy Human Subjects
The purpose of this study is to assess the pharmacodynamic effects, pharmacokinetics, and safety of two oral formulations (tablet and capsule) of LX1033 in normal healthy volunteers.
- Trial name
- NCT01411800
- Testing
- 250 mg capsule, 250 mg tablets
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Lexicon Pharmaceuticals
Functional Gastrointestinal Disorders
Emotion Focused Therapy in Irritable Bowel Syndrome Patients
The study was quasi-experimental including patients in two intervention and control groups. Three measurements were done: pretest, post-test, and a two-months follow-up.
- Trial name
- NCT02657668
- Testing
- Emotion Focused Therapy
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Najafabad Branch
Irritable Bowel Syndrome
Microbiota Community of Irritable Bowel Syndrome in Episodes and Remission Phase
Analyze microbiota community of irritable bowel syndrome in episodes phase and remission phase.
- Trial name
- NCT02566629
- Testing
- collect faeces from participants
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shandong University
Bowel Symptoms, Depression Disorders
The Effect of Inulin in Irritable Bowel Syndrome
Purpose: This study was conducted to evaluate the effect of inulin on bowel symptoms, depression and quality of life in individuals with constipation-dominant irritable bowel syndrome.
- Conditions
- Bowel Symptoms, Depression Disorders, Inulin, Constipation
- Trial name
- NCT06610188
- Testing
- Prebiotic group
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Mardin Artuklu University
Fibromyalgia, Irritable Bowel Syndrome
Patient-reported Outcome Measures (PROMs) in Patients With Bodily Stress Syndrome: Protocol for a Prospective Cohort Study
This cohort study implements patient reported outcome measures (PROMs) for patients with bodily stress syndrome in a clinic for functional disorders.
- Conditions
- Fibromyalgia, Irritable Bowel Syndrome, Somatic Symptom, Chronic Fatigue Syndrome
- Trial name
- SYMPA (NCT04667611)
- Testing
- Psychosocial interventions
- Where
- Finland
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Irritable Bowel Syndrome, Inflammatory Bowel Diseases
The Ecological Role of Yeasts in the Human Gut
Irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) (categorised into Crohn's disease (CD) and ulcerative colitis (UC)) are chronic gut disorders with debilitating symptoms that profoundly impact quality of life…
- Conditions
- Irritable Bowel Syndrome, Inflammatory Bowel Diseases, Gastrointestinal Disease
- Trial name
- YIG (NCT04138225)
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Grace Ward
IBS - Irritable Bowel Syndrome
Fecal Transplantation in Patients With IBS
The study will characterize the biology of FMT in the context of IBS prior to wider clinical application of the method. Given the ethical concerns of unknown and long-term adverse effects of FMT therapy, the study will include…
- Trial name
- NCT03333291
- Testing
- fecal suspension
- Where
- Norway
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Gulf War Illness, Persian Gulf War Syndrome
Study of Gulf War Illness (GWI) by Comparing GWI and Healthy Veterans
Determine if: genetic differences of CNDP1 gene the previously defined GWI/Chronic Fatigue Syndrome (GWI/CFS) cerebrospinal fluid proteome contents psychometric other variables can differentiate between veterans of the 1990-1991…
- Trial name
- NCT00810225
- Where
- United States
- Volunteers
- 516 people, healthy volunteers welcome
- Sponsor
- Georgetown University
IBS - Irritable Bowel Syndrome
Pre-analytical Influences on a Blood Test Study
Chronic diarrhoea is common and often believed to result from irritable bowel syndrome (IBS). However, up to 50% of patients with an IBS diagnosis may have something called Bile Acid Diarrhoea (BAD) instead.
- Trial name
- NCT05434949
- Testing
- Blood test, Analyses of samples
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- The Royal Wolverhampton Hospitals NHS Trust
Irritable Bowel Syndrome, Cyclical Vomiting Syndrome
Multi Modal Imaging: An MRI Study to Investigate Differences in the Structure and the Function of the Brain at Rest.
The structural/RSN study involves Structural and Resting State Neuroimaging. The purpose of Structural Neuroimaging is to use MRI technology to identify cortical and white matter morphometric differences between patients with…
- Conditions
- Irritable Bowel Syndrome, Cyclical Vomiting Syndrome, Ulcerative Colitis, Vulvodynia
- Trial name
- MMI (NCT01517516)
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Irritable Bowel Syndrome, Relief of Irritable Bowel Syndrome Symptoms
Effects of Cultura Yoghurt in Irritable Bowel Syndrome (IBS) Patients on Intestinal and Immunological Changes
To determine the effect of cultura probiotic yoghurt on number of responders to treatment during 8 weeks of treatment in comparison to placebo.
- Conditions
- Irritable Bowel Syndrome, Relief of Irritable Bowel Syndrome Symptoms, Quality of Life
- Trial name
- NCT01127828
- Testing
- Arla Yoghurt with no probiotic, Probiotic yoghurt (Cultura)
- Where
- Sweden
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Good Food Practice, Sweden