Clinical trials: Functional Constipation
Functional Constipation, Gastrointestinal Disorders
A Randomized, Open-label, Three-arm Study of MZRW on Tolerability, Exposure and Pharmacokinetics
This is a randomized open-label, three-arm, phase 1 clinical study. The investigators aim to investigate a Chinese Proprietary Medicine, MZRW on its tolerability, system exposure and pharmacokinetics profile.
- Trial name
- NCT02359396
- Testing
- MZRW
- Where
- China
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
Functional Constipation, Therapeutic Touch
Effect of Therapeutic Touch on Functional Constipation in Infants and Young Children
The aim of the study is to determine the effect of therapeutic touch on functional constipation in infants and young children.
- Conditions
- Functional Constipation, Therapeutic Touch, Infants, Children
- Trial name
- NCT06353841
- Testing
- Therapeutic Touch
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Burdur Mehmet Akif Ersoy University
Spinal Cord Injuries, Constipation
Use of a Prokinetic Agent as an Adjunct to Thrice Weekly Bowel Care After SCI
To measure a baseline for each subject, an abdominal x-ray (KUB) was performed, the SCI Bowel Survey and Treatment Satisfaction Questionnaire (TSQM) were administered and the subject's weight determined.
- Conditions
- Spinal Cord Injuries, Constipation, Neurogenic Bowel
- Trial name
- TWBC (NCT04671030)
- Testing
- Neostigmine and Glycopyrrolate, Iontophoresis
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Constipation Chronic Idiopathic
Evaluation of the Triple Management Program in the Management of Functional Chronic Constipation in Children
Abstract Background: Chronic constipation is a common disease in children, 3% all children visit gastroenterology clinics with different types and complains.
- Trial name
- NCT06082622
- Testing
- laxatives
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Minia University
Constipation, Fecal Incontinence
Diagnosis of Functional Defecation Disorders in Childhood
Purpose To compare different kinds of diagnostic investigations in order to identify the most sensitive and least invasive when diagnosing constipation.
- Trial name
- NCT00230360
- Where
- Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Constipation
A Study to Evaluate the Effects of a Natural Supplement in Adults With Chronic Functional Constipation
Constipation is common in the general population, especially in women and in the elderly. Hard stool is a complaint often associated with constipation, which suggests that stool softening would provide a major benefit in the…
- Trial name
- NCT02073006
- Testing
- Natural Fibre Supplement
- Where
- Ireland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Atlantia Food Clinical Trials
Functional Constipation
The Effect of Probiotics on Functional Constipation in the Elderly
The main scope of the proposed research in the framework is to investigate the effect of probiotic bacteria Lactobacillus acidophilus LA3, Bifidobacterium animalis ssp.
- Trial name
- NCT04506801
- Testing
- Probalans senior
- Where
- Croatia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Katarina Fehir Šola
Bowel Symptoms, Depression Disorders
The Effect of Inulin in Irritable Bowel Syndrome
Purpose: This study was conducted to evaluate the effect of inulin on bowel symptoms, depression and quality of life in individuals with constipation-dominant irritable bowel syndrome.
- Conditions
- Bowel Symptoms, Depression Disorders, Inulin, Constipation
- Trial name
- NCT06610188
- Testing
- Prebiotic group
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Mardin Artuklu University
Colic, Infantile, Milk Allergy, Cow's
Validation Of A Parent Administered Symptom Score For Unsettled Infants (Every Baby is UnIQue)
It's common for infants to be unsettled, especially in the first few months of life. While this is often normal, persistent symptoms can be stressful for families.
- Conditions
- Colic, Infantile, Milk Allergy, Cow's, Gastro Oesophageal Reflux Disease, Atopic Dermatitis (Eczema)
- Trial name
- NCT07121062
- Testing
- Online parent administered questionnaire
- Where
- United Kingdom
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Functional Constipation in Children
Is Vitamin D Deficiency Linked to Functional Constipation In Children
Constipation is one of the most common causes of patient visits to pediatric clinics. Prevalence of constipation is estimated between 1.9-27.2% in the USA (Rasquin et al., 2006).
- Trial name
- NCT06657313
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Benha University
Feasibility Studies
A Pilot Study To Evaluate the Effects of Lactobacillus Supplements
This is a feasibility study to evaluate a decentralized (remote) clinical trial in Korea. In this study, an open-label, randomized, remote clinical trial to evaluate the effects of lactobacillus supplements on alleviating…
- Trial name
- NCT05520073
- Testing
- Lactobacillus plantarum, Vitamin C
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Functional Colonic Disease, Fecal Incontinence
Effect of Lumbo-sacral Magnetic Stimulation on Colonic Motility
The purpose of this study is to evaluate the effect of sacral nerve magnetic stimulation on the colonic motility in healthy subjects, in incontinent and constipated patients.
- Trial name
- NCT00213317
- Testing
- lombo-sacral magnetic stimulation
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Functional Constipation
Effect of Probiotics on Functional Constipation in Adults
Introduction: Functional constipation is a symptom-based gastrointestinal disorder without an organic origin (eg, bowel obstruction). It has a prevalence of 14% in adults.
- Trial name
- PROBCON (NCT04437147)
- Testing
- 3 Billion UFC strains of probiotics, 8 Billion UFC strains of probiotics
- Where
- Brazil
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Luciane Cruz Lopes
Rome IV Functional Constipation
Microbiome Analysis of Constipated Versus Non-constipation Patients
This study intends to evaluate the microbiome of chronically constipated patients as compared to those with a non-constipated gastrointestinal system.
- Trial name
- NCT04106232
- Testing
- No change in procedure except for specimen collection throughout procedure
- Where
- 3 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- HyGIeaCare, Inc.
Functional Constipation
Dose-ranging Efficacy of Polydextrose Supplement on Colonic Transit Time and Symptoms in Adults With Functional Constipation
This study will investigate the effectiveness of Polydextrose, a dietary fiber, at decreasing Colonic Transit Time and the gastrointestinal symptoms of Functional Constipation.
- Trial name
- NCT02314936
- Testing
- Litesse powder containing 12 g polydextrose, Litesse powder containing 8 g polydextrose, Litesse powder containing 4 g polydextrose
- Where
- Canada
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- KGK Science Inc.
Irritable Bowel Syndrome
Curcumin (Tumeric) in the Treatment of Irritable Bowel Syndrome: A Randomized-Controlled Trial
Evidence exists to support low-grade inflammation as the inciting factor leading to visceral hypersensitivity and alteration in motility in irritable bowel syndrome.In the medical literature,there is ample in vitro and in vivo…
- Trial name
- CuTIBS (NCT00779493)
- Testing
- curcumin
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Constipation - Functional, Depressive Symptoms
FMT Treating Constipation Patients With Depression and/or Anxiety Symptoms - Clinical Efficacy and Potential Mechanisms
Constipated patients often have mental problems such as depression and anxiety due to difficult defecation. Our previous studies have proved the efficacy of FMT treating constipation.
- Conditions
- Constipation - Functional, Depressive Symptoms, Anxiety Symptoms, Gut-Brain Disorders
- Trial name
- NCT03233100
- Testing
- FMT
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jianfeng Gong
Chronic Pancreatitis, Inflammatory Bowel Diseases
Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study
This is a prospective, descriptive, observational research study designed to observe and document the clinical practice by domain experts, and how the knowledge of new findings that are published in the medical literature affect…
- Conditions
- Chronic Pancreatitis, Inflammatory Bowel Diseases, Hepatitis, NASH - Nonalcoholic Steatohepatitis
- Trial name
- GREAT1 (NCT04306939)
- Testing
- venipuncture, Questionnaires, Additional Sample Collections
- Where
- United States
- Volunteers
- 120,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Constipation
Effects of Alpha-1 Antagonist, Stress and Relaxation on Anorectal Functions
This study is designed to better understand the effects of effects of stress, relaxation, and a medication alfuzosin on bowel control and emptying in healthy people and patients with bowel problems.
- Trial name
- NCT01834729
- Testing
- Alfuzosin
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Functional Constipation, Healthy
Effect of scFOS on Increase in Stool Frequency in Constipated People
The study aims to evaluate the effects of short-chain fructo-oligosaccharides on the frequency and consistency of stools in subjects with functional constipation.
- Trial name
- CONSYST (NCT03707002)
- Testing
- scFOS, Maltodextrin
- Where
- France
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Syral