Clinical trials: Functional Constipation, open to volunteers
Bloating, Rifaximin
Rifaximin Treatment in Bloating Predominant Functional Bowel Disorders
This randomized, double-blind, placebo-controlled trial will evaluate the effects of a 14-day course of rifaximin on bloating symptoms, gut microbiota, microbial metabolites, and intestinal gases in adults with Rome V irritable…
- Conditions
- Bloating, Rifaximin, Functional Bowel Disorder, Irritable Bowel Syndrome
- Trial name
- NCT07522255
- Testing
- Rifaximin (drug)
- Where
- Thailand
- Volunteers
- 78 people
- Sponsor
- Mahidol University
Functional Constipation
Core-Based Movement and Nutritional Counselling for Stress and Metabolic Outcomes in Overweight Women With Functional Constipation
This study will investigate the effect of core-based movement and nutritional counselling on stress, serum cortisol, and lipid profile in overweight women with functional constipation.
- Trial name
- NCT07694830
- Testing
- Guideline-Based Nutritional Counselling, Core-Based Movement Exercise Program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Functional Constipation (FC)
Fiber Nutritional Supplement for Management of Constipation During Pregnancy
This study aims to evaluate the effectiveness of a daily Fiber Nutritional Supplement (Materna® Opti fiber), containing partially hydrolyzed guar gum (PHGG) and vitamins C, D, zinc, and selenium, combined with nutritional…
- Trial name
- NCT07588633
- Testing
- fiber supplement (PHGG) with counselling for constipation management
- Where
- Brazil
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Refractory Constipation, Somatic Symptom Disorder (DSM-5)
Evaluation of Fluoxetine for Refractory Constipation With Somatic Symptom Disorder Features
This single-center, randomized, double-blind, placebo-controlled trial evaluates the efficacy and safety of fluoxetine (40 mg/day) versus placebo in 194 adults with refractory chronic constipation exhibiting Somatic Symptom…
- Conditions
- Refractory Constipation, Somatic Symptom Disorder (DSM-5), Functional Constipation (FC)
- Trial name
- REFLECT (NCT06506136)
- Testing
- Fluoxetine
- Volunteers
- 194 people
- Sponsor
- Zhifeng Zhao, PhD
Bowel Dysfunction, Dysmotility
Comparison of a New Non-invasive Device With the Invasive Gold-standard Investigation to Assess Function of the Large Bowel in Children
The goal of this clinical trial is to learn if the new non-invasive device (Body Surface Colonic Mapping) works to accurately assess colonic movement and function in children.The main questions it aims to answer are: Are Body…
- Conditions
- Bowel Dysfunction, Dysmotility, Hirschsprung Disease, Anorectal Malformations
- Trial name
- NCT07789782
- Testing
- Body Surface Colonic Mapping
- Where
- Australia
- Volunteers
- 50 people
- Sponsor
- Murdoch Childrens Research Institute
Functional Constipation (FC)
Implementation of Physical Therapy Protocol for Functional Constipation
The goal of this randomized controlled trial is to investigate the effects of standard medical treatment alone and the effects of adding different physiotherapy protocols to standard medical treatment on constipation severity…
- Trial name
- NCT07719504
- Testing
- Standard medical treatment, Maitland orthopedic manual therapy (MOMT), Russian current stimulation (ERS)
- Volunteers
- 60 people
- Sponsor
- Cairo University
Eosinophilic Esophagitis, Gastroesophageal Reflux Disease (GERD)
Indiana University Gastrointestinal Motility Diagnosis Registry
Develop a registry (list of patients) with accurate clinical motility diagnosis. This registry will help the doctors to identify the patients with specific disease conditions.
- Conditions
- Eosinophilic Esophagitis, Gastroesophageal Reflux Disease (GERD), Gastroparesis, Functional Vomiting
- Trial name
- NCT04506593
- Testing
- no intervention
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Indiana University
Parkinsons Disease (PD), Constipation - Functional
Nutritional Intervention for Constipation Symptoms in Patients With Parkinson's Disease
The goal of this clinical trial is to evaluate whether a dietitian-guided nutritional intervention can improve constipation symptoms in people with Parkinson's disease (PD).
- Trial name
- NUTRI-GUT-PD (NCT07213856)
- Testing
- Dietitian-Guided Nutritional Intervention
- Where
- Brazil
- Volunteers
- 54 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Inflammatory Bowel Disease (IBD), Irritable Bowel Syndrome (IBS)
Enabling Microbiomics- Driven Personalized Nutrition
The goal of this observational research study is to determine how diet contributes to various gastrointestinal related conditions.
- Conditions
- Inflammatory Bowel Disease (IBD), Irritable Bowel Syndrome (IBS), Celiac Disease, Diarrhea
- Trial name
- EMPOWER (NCT06657001)
- Where
- United States
- Volunteers
- 4,001 people
- Sponsor
- Mayo Clinic
Functional Constipation
Probiotics for Constipation Relief in Adults
This study aims to evaluate the efficacy and safety of Bifidobacterium animalis subsp. lactis BLa36 in adults with functional constipation.
- Trial name
- NCT07507955
- Testing
- Probiotic, Maltodextrin, High-activity probiotic group
- Where
- China
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Constipation, Cancer
A Study of Herbal Supplements in Cancer Survivors With Constipation
The purpose of this study is to find out whether MZRW is an effective treatment for constipation in cancer survivors. The researchers will compare MZRW with placebo, a pill that looks like MZRW and is given in the same way, but…
- Conditions
- Constipation, Cancer, Functional Constipation
- Trial name
- NCT07091084
- Testing
- MZRW
- Where
- 7 sites in United States
- Volunteers
- 70 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Functional Constipation (FC)
Dose-Effect Response in Acupuncture for Functional Constipation
This is a single-center, randomized, parallel-group trial evaluating the dose-response relationship of two experimental interventions: manual acupuncture and electroacupuncture for functional constipation.
- Trial name
- NCT07506122
- Testing
- Manual Acupuncture, Electroacupuncture
- Where
- 2 sites in China
- Volunteers
- 72 people
- Sponsor
- Tongji Hospital
Functional Constipation
Co-supplementation With Bifidobacterium Longum W11 and Colopectin for Maintenance Therapy in Children With Functional Constipation
Functional constipation is a common condition in children and often requires prolonged maintenance treatment with macrogol. This randomized, double-blind, placebo-controlled trial will evaluate whether co-supplementation with…
- Trial name
- NCT07536698
- Testing
- Bifidobacterium longum W11 (Bowell®) + Colopectin (Colopectin®)
- Volunteers
- 100 people
- Sponsor
- Liaquat University of Medical & Health Sciences
Gastrointestinal Motility Disorders in Children, Hirschsprung Disease
Improvement of Understanding of Pediatric Sacral Neuromodulation: Therapeutic Strategies and Outcome Variables
The goal of this study is to learn about the effects of sacral neuromodulation in pediatric patients with gastrointestinal motility disorders.
- Conditions
- Gastrointestinal Motility Disorders in Children, Hirschsprung Disease, Constipation - Functional
- Trial name
- SMART-GUT (NCT07519915)
- Testing
- SNM/MRI/EMG
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Friedrich-Alexander-Universität Erlangen-Nürnberg
Functional Constipation
The Efficacy and Palatability of Developed Polyethylene Glycol-based Formula for Children With Functional Constipation
This study aims to evaluate the efficacy and palatability of a developed polyethylene glycol-based formula compared with the standard polyethylene glycol (PEG) in the treatment of children with functional constipation for 8…
- Trial name
- NCT06357897
- Testing
- Local PEG4000, Commercial PEG4000
- Where
- Thailand
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Constipation - Functional
Chronic Ingestion of Fructooligosaccharide and Psyllium on Intestinal Transit in Women With Functional Constipation: A Randomized Crossover Trial
The goal of this clinical trial is to evaluate the effect of dietary fibers in the treatment of functional constipation in women. It will also assess the potential side effects associated with fiber consumption.
- Trial name
- NCT07202481
- Testing
- Psyllium powder, Fructooligosaccharide
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- Federal University of Minas Gerais
Constipation - Functional
Effectiveness and Safety of Benemix® in Constipation
The goal of this clinical trial is to find out whether the functional food Benemix® helps treat constipation in adults and whether it is safe to use.
- Trial name
- (Benemix-UdeA) (NCT07427914)
- Testing
- Benemix®, a functional food composed of turmeric, onion, magnesium, and lactose-free, skimmed milk powder
- Volunteers
- 80 people
- Sponsor
- Universidad de Antioquia
Constipation, Constipation - Functional
Soluble and Osmotic Fibre (SOLOS) Diet for Constipation
This research aims to study the dual effectiveness of incorporating soluble fibre and osmotic carbohydrates (SOLOS), with or without restricting fructans and GOS, and present novel findings in managing GI symptoms in patients…
- Conditions
- Constipation, Constipation - Functional, Constipation Chronic Idiopathic, Constipation Predominant Irritable Bowel Syndrome
- Trial name
- SOLOS (NCT07388589)
- Testing
- Diet
- Where
- Singapore
- Volunteers
- 180 people
- Sponsor
- Singapore Institute of Technology
Constipation - Functional, Chronic Constipation
The Efficacy and Safety of Microbiota Transplantation Combined With Prebiotics for Treatment of Functional Constipation
Chronic constipation is a common gastrointestinal disorder with a global prevalence of approximately 15%, severely impacting daily life and quality of life.
- Conditions
- Constipation - Functional, Chronic Constipation, Fecal Microbiota Transplantation
- Trial name
- NCT07386795
- Testing
- FMT
- Where
- China
- Volunteers
- 19 people
- Sponsor
- Peking Union Medical College Hospital
Constipation - Functional, Fecal Microbiota Transplantation (FMT)
The Safety and Efficacy of Fecal Microbiota Transplantation Combined With Nutritional Intervention in the Treatment of Functional Constipation：a Pilot Study
Chronic constipation is a common gastrointestinal disease with a global prevalence of about 15%, significantly affecting daily life and quality of life.
- Conditions
- Constipation - Functional, Fecal Microbiota Transplantation (FMT), Chronic Constipation
- Trial name
- NCT07387952
- Testing
- FMT
- Where
- China
- Volunteers
- 5 people
- Sponsor
- Peking Union Medical College Hospital