Clinical trials: Functional Disorder of Intestine
Irritable Bowel Syndrome
A Clinical Study to Determine the Safety and Efficacy of An Oral Probiotic Supplementation in the Management of Irritable Bowel Syndrome With Protein Digestion.
This is an open-label, two-arm, prospective, interventional, in-use safety and efficacy study of an oral probiotic supplementation in adult subjects having irritable bowel syndrome.
- Trial name
- NCT06687720
- Testing
- MetBroma
- Where
- India
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- NovoBliss Research Pvt Ltd
Irritable Bowel Syndrome, Gallstone Disease
Pharmacokinetics, Bioequivalence, and Safety Study of Trimedat® 76,95 mg Orally Disintegrating Tablets and Trimedat® 100 mg Tablets in Healthy Volunteers.
This study aims to evaluate pharmacokinetic profile, safety and establish bioequivalence of the investigational drug Trimedat® 76,95 mg orally disintegrating tablets compared to the reference drug Trimedat® 100 mg tablets in…
- Conditions
- Irritable Bowel Syndrome, Gallstone Disease, GERD, Biliary Dyskinesia
- Trial name
- NCT07421011
- Testing
- Trimedat®
- Where
- Russia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Valenta Pharm JSC
Pelvic Pain, Abdominal Pain
Female Chronic Pelvic Pain
The purpose of this study is to investigate the frequency and severity of chronic pelvic pain (CPP) in adult women living in Copenhagen Country and Zealand Country (total population 2,4 million), Denmark, in relation to selected…
- Conditions
- Pelvic Pain, Abdominal Pain, Painful Bladder Syndrome, Interstitial Cystitis
- Trial name
- Female CPP (NCT01255345)
- Testing
- Chronic pelvic pain
- Where
- Denmark
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital at Herlev
Fecal Incontinence, Constipation
Studies in Patients With Defecatory Disorders
Defecatory disorders like chronic constipation and faecal incontinence affect 25% of the population with rising incidence. Defecatory disorders pose a major health care burden and are poorly recognized and treated.
- Trial name
- NCT03317938
- Testing
- Fecobionics
- Where
- 2 sites in Hong Kong
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Giome
Muscle Loss
Galactooligosaccharide and Aging
Sarcopenia is a progressive muscle disease, most commonly affecting older individuals, that is categorised by 1) low muscle strength, 2) low muscle quantity or quality, and 3) low physical performance.
- Trial name
- NCT06411964
- Testing
- Prebiotic
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Bath
Intestinal Barrier Function, Chronic Inflammation
Reduction of Obesity-Associated Intestinal Inflammation by Low-Fat Dairy Yogurt
The main objective of this work is to conduct a clinical trial in obese and non-obese individuals testing the ability of low-fat dairy yogurt to improve gastrointestinal health and reduce chronic inflammation.
- Trial name
- NCT01686204
- Testing
- Low fat dairy yogurt, Soy pudding
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Irritable Bowel Syndrome, Quality of Life
Effect of Stress Ball on Irritable Bowel Syndrome
Objective: This study will be conducted to evaluate the effect of stress ball on symptom severity, quality of life, depression, anxiety and stress in patients with irritable bowel syndrome (IBS).
- Conditions
- Irritable Bowel Syndrome, Quality of Life, Depression, Anxiety
- Trial name
- NCT05931107
- Testing
- Stress ball practice group (Stress ball squeezing)
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Bedriye Cansu DEMİRKIRAN
Inflammatory Bowel Diseases, Functional Gastrointestinal Disorders
The Healthy Endoscopy Study
Researchers at Seattle Children's Research Institute want to find ways to understand gastrointestinal disease such as Inflammatory Bowel Disease (IBD), Irritable Bowel Syndrome (IBS) and Graft-Versus-Host-Disease (GVHD).
- Trial name
- NCT04369963
- Testing
- Esophagogastroduodenoscopy and Colonoscopy with Biopsies
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Irritable Bowel Syndrome (IBS)
Deep Learning-Based Confocal Laser Microendoscopy Feature Atlas Construction and Its Application in Intelligent Diagnosis of Irritable Bowel Syndrome
In this study, the healthy control group and IBS patients are taken as the research subjects, and CLE is applied to image and analyze the enrolled persons respectively, to derive and compare the characteristic microstructural…
- Trial name
- NCT07051226
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
NAFLD, Obesity
Influence of a Mediterranean Diet Combined With a Physical Activity Intervention, on NAFLD and Inflammation Parameters.
The study in question is an interventional study with nutritional intervention. The aim of the study is to evaluate whether the adoption of two different models of Mediterranean Diet, based on the different percentage of…
- Conditions
- NAFLD, Obesity, IBS
- Trial name
- NAFLD-POS5 (NCT06275906)
- Testing
- Mediterranean diet and moderate intensity physical exercise (outdoor walking).
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Irritable Bowel Syndrome, Food Sensitivity
Confocal Laser Endomicroscopy to Determine Influence of Food Antigens on Mucosal Integrity
Irritable bowel syndrome (IBS) is mainly associated with food intolerance and presents a particular challenge in gastrointestinal practice.
- Conditions
- Irritable Bowel Syndrome, Food Sensitivity, Healthy Controls
- Trial name
- RDS_CLE (NCT05056610)
- Testing
- food antigens on duodenal mucosa
- Where
- Germany
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Acupressure, Post-Op Complication
Effect of Acupressure on Recovery of Bowel Function in Patients Post Cesarean Section
Research objectives To compare the efficacy of acupressure with no acupressure to examine time to first flatus in patient post cesarean section ; Acupressure at ST-36 Zusanli (lateral to anterior crest of tibia, in the tibialis…
- Conditions
- Acupressure, Post-Op Complication, Cesarean Section, Bowel Ileus
- Trial name
- NCT04620850
- Testing
- Acupressure
- Where
- Thailand
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Constipation, Intestinal Functional Disorder
The Efficacy Evaluation of TCI604 Probiotic on Intestinal Function Improvement
The objective of this study is to evaluate whether the TCI604 probiotics has the potential to enhance human gut function and alleviate constipation.
- Trial name
- NCT07135362
- Testing
- TCI604 probiotics
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Inflammatory Bowel Diseases, Irritable Bowel Syndrome
Randomized Controlled Trial of Citizen-targeted Evidence-based Resources
The purpose of this study is to determine whether an online resource developed to aid health consumers in making health decisions and better support them to seek quality evidence before other evidence is effective in the context…
- Trial name
- NCT04693780
- Testing
- Structured guide, List
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- McMaster University
NAFLD, IBS
Effects of Tomato Consumption on Steatosis, Intestinal Function and Glucose and Lipid Metabolism in Subjects With NAFLD
The study in question is an interventional study with nutritional intervention. the aim of the study is to evaluate whether a diet enriched with tomatoes can have favorable effects on: specific aspects associated with NAFLD, such…
- Trial name
- NCT06389851
- Testing
- Experimental: Case Group - Tomato-free diet, Experimental: Case group - Diet enriched with tomatoes
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Irritable Bowel Syndrome, Vaginal Health
A Single Group Study to Evaluate the Effects of a Vaginal Probiotic on Vaginal and Digestive Health
This is a virtual single-group study that will last 12 weeks. Participants will take 1 capsule every day, with water. Questionnaires will be completed at baseline, 2 weeks, 4 weeks, and 12 weeks.
- Trial name
- NCT06124313
- Testing
- Vaginal Probiotic
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rael
Irritable Colon, Irritable Bowel Syndrome (IBS)
Study On The Effect Of GW876008 On Cerebral Blood Flow In Irritable Bowel Syndrome (IBS) Patients And Healthy Volunteers
This is a three-period crossover study to compare GW876008 and placebo to see if GW876008 will normalise blood flow responses after different emotional stimuli.
- Trial name
- NCT00376896
- Testing
- GW876008 200mcg, GW876008 20mcg
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Gastroschisis
Evaluation of Glycerin Suppositories to Improve Bowel Function in Gastroschisis
Gastroschisis is a congenital defect of the abdominal wall that leads to evisceration of various amounts of the abdominal organs.
- Trial name
- NCT03355326
- Testing
- Glycerin Suppository
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Indiana University