Clinical trials: Functional Disturbance as Result
Atrial Fibrillation, Inflammatory Marker
Red Cell Distribution Width as a Predictor for Post Operative Atrial Fibrillation After Open Heart Surgries
In this study we investigate the correlation between RDW and POAF, as we use the RDW as a predictor for inflammation for prediction of POAF
- Conditions
- Atrial Fibrillation, Inflammatory Marker, Heart; Surgery, Heart, Functional Disturbance as Result
- Trial name
- NCT06286111
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Functional Disturbance as Result
A Clinical Study to Compare Functional Outcomes After Surgery Using a Transverse or Longitudinal Surgical Incision in the Skin.
Trigger finger is a common pathology in the hand. Patients suffer from pain and depending on which tasks, patients have difficulty to perform them.
- Trial name
- NCT06267105
- Testing
- Longitudinal incision, Transverse incision
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- Corporacion Parc Tauli
Heart; Surgery, Heart, Functional Disturbance as Result
Trial to Compare Different Strategies of Mean Arterial Pressure Management During Cardiopulmonary By-pass
Background: One of the main goals of the Cardiopulmonary By-Pass (CPB) is targeting an adequate Mean Arterial Pressure (MAP), in order to maintain appropriate perfusion pressures in all end-organs during heart surgery.
- Trial name
- MAP (NCT05740397)
- Testing
- Management of mean arterial pressure during cardiopulmonary by-pass in cardiac surgery interventions. The MAP will be mantained in the range of values of each study arm
- Where
- Italy
- Volunteers
- 900 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Role of Neurofilment in Diagnosis of Multiple Sclerosis
Neurofilament Light Chain as Diagnostic and Prognostic Marker in naïve Multiple Sclerosis Patients
Neurofilament protein detected in the serum appears to be a good marker for the extent of active neurodegeneration. Chitinase may also be a good marker reflecting the degree of astrocyte activation, or damage in active lesions…
- Trial name
- NFLMS (NCT06197841)
- Where
- Egypt
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Assiut University
Heart; Surgery, Heart, Functional Disturbance as Result, Anxiety
Combination of Music and Relaxing Light on the Patient's Anxiety After Cardiac Surgery in the Intensive Care Unit
Cardiac surgery is not trivial. It requires opening the thorax in certain indications: coronary artery bypass grafting, valve replacements or plasties, aortic dissection, etc.
- Conditions
- Heart; Surgery, Heart, Functional Disturbance as Result, Anxiety, Pain, Postoperative, Delirium
- Trial name
- RéaRelax (NCT05178680)
- Testing
- relaxation session combining music and soft light
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Poitiers University Hospital
Heart; Surgery, Heart, Functional Disturbance as Result, Pain, Postoperative
Development of Open Heart Surgery Patient Care Protocol and Its Effect on Post-sternotomy Pain
Open heart surgery method is generally used in the treatment of cardiovascular diseases. Sternotomy is the process of opening the sternum. After sternotomy, individuals experience ongoing pain in the anterior thorax.
- Conditions
- Heart; Surgery, Heart, Functional Disturbance as Result, Pain, Postoperative, Nursing Caries
- Trial name
- NCT05902052
- Testing
- Care Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kutahya Health Sciences University
Lung Diseases, Mechanical Ventilation
Mitochondrial Dysfunction of Alveolar and Circulating Immune Cells During Acute Respiratory Distress Syndrome: Impact of Infectious Aggression and Alveolar Stretching as a Result of Mechanical Ventilation.
Sepsis leads to a deregulated host response that can lead to organ failure. During sepsis, experimental and clinical data suggest the occurrence of mitochondrial dysfunctions, particularly in circulating muscle and monocytes…
- Conditions
- Lung Diseases, Mechanical Ventilation, Bronchoalveolar Lavage
- Trial name
- PNEUMOCHONDRIE (NCT03955887)
- Testing
- bronchoalveolar lavage fluid (BAL), Venous blood
- Where
- France
- Volunteers
- 28 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Heart; Surgery, Heart, Functional Disturbance as Result
Pre-operative Carriage of Respiratory VIRUSes, and Acute Respiratory Distress Syndrome After Heart Surgery
The main objective of our study is to determine whether asymptomatic influenza virus carriage is associated with an increased risk of post-operative Acute Respiratory Distress Syndrome (ARDS) after cardiac surgery.
- Trial name
- VIRUS-ATTAC (NCT04562207)
- Testing
- Screening for respiratory virus infection
- Where
- 5 sites in France
- Volunteers
- 1,256 people
- Sponsor
- Rennes University Hospital
Heart; Surgery, Heart, Functional Disturbance as Result
Evaluation of Damaging Factors to Endothelial Glycocalyx During Heart Surgery.
Evaluation of endothelial glycocalyx damage in on-pump conventional coronary artery bypass surgery using a syndecan-1 (CD138) blood test. The study will be carried out in two stages.
- Trial name
- NCT03491163
- Testing
- Syndecan-1 concentration evaluation
- Where
- Lithuania
- Volunteers
- 147 people
- Sponsor
- Lithuanian University of Health Sciences
Heart; Surgery, Heart, Functional Disturbance as Result, Pediatric ALL
Oblique Versus Transverse Orientation Approach for Internal Jugular Venous Cannulation in Pediatrics
this study aimed to compare oblique versus transverse orientation approach in jugular venous cannulation in term of cannulation success in pediatric heart surgery patients
- Trial name
- NCT05656937
- Testing
- internal jugular venous cannulation
- Where
- Indonesia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Individual Psychiatric Disorder, Couple Dysfunction
Assessing Psychotherapy Outcome With Feedback
This study is a comparison of client outcomes in two different types of psychotherapy treatment. In one condition clients will receive treatment-as-usual (TAU); the therapy that they would normally receive.
- Conditions
- Individual Psychiatric Disorder, Couple Dysfunction, Family Dysfunction
- Trial name
- NCT02023736
- Testing
- Systemic Therapy Inventory of Change (STIC), Treatment as Usual
- Where
- 4 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- The Family Institute at Northwestern University
Left Ventricular Systolic Dysfunction
3D & Speckle Tracking Together as a Marker for Early Outcome in Cardiac Surgery
Patients presenting with Left Ventricle (LV) dysfunction undergoing cardiac surgery are at increased risk of perioperative morbidity and mortality.
- Trial name
- NCT02642770
- Testing
- Transesophageal echocardiography
- Where
- India
- Volunteers
- 73 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Mild Cognitive Impairment, White Matter Hyperintensity
Use of Gou-Teng to Treat Patients With Mild Cognitive Impairment
Mild cognitive impairment (MCI) is a pre-dementia condition commonly occurs in elderly people. As Hong Kong has become an aged society, the prevalence of dementia and MCI in Hong Kong has increased substantially in recent…
- Trial name
- NCT04532697
- Testing
- Uncaria Rhynchophylla (Gou-Teng)
- Where
- Hong Kong
- Volunteers
- 56 people
- Sponsor
- Chinese University of Hong Kong
Post Cardiac Arrest Patient Who Was Treated by Hypothermia Protocol
Plasma Neutrophil Gelatinase-associated Lipocalin (NGAL) as Early Biomarker for Renal Dysfunction and Good Neurologic Outcome in Out of Hospital Cardiac Arrest Patients
Postresuscitation disease is a constellation of disorders related to whole-body ischemia and reperfusion syndrome. It includes hypoxic damage in brain, liver, kidney, heart and other organ.
- Trial name
- NCT01987466
- Testing
- Serum NGAL level
- Where
- South Korea
- Volunteers
- 73 people
- Sponsor
- Yonsei University
Mild Cognitive Impairment, Lack of Physical Activity
Change in Executive Function and IADL Using a Virtual Supermarket Environment Among People With MCI
The aim of the study is to investigate the feasibility of using a virtual supermarket as an intervention tool for overcoming deficits in executive function as well as enhancing IADL performance among persons with Mild Cognitive…
- Trial name
- EF-VAPS (NCT01103453)
- Testing
- Virtual Action Planning Supermarket (VAP-S) Software
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Carmel Medical Center
Heart; Surgery, Heart, Functional Disturbance as Result
The Effect of 10 Repetitions of Deep Breathing Exercises
The goal of this clinical trial is to learn and assess the effect of 10 repetitions of deep breathing exercises every 3 hours compared to 3 repetitions of deep breathing exercises on the sleep quality of patients after heart…
- Trial name
- NCT06435715
- Testing
- 10 Repetitions of Deep Breathing Exercise, 3 Repetitions of Deep Breathing Exercise
- Where
- Indonesia
- Volunteers
- 50 people
- Sponsor
- Universitas Indonesia
Endothelial Dysfunction
Endothelial Dysfunction As A Predictor Of Perioperative Outcome
The goal of this clinical research study is to learn whether the inability of certain blood vessel cells (endothelial cells) to function properly may help researchers to predict who is at risk for complications after surgery and…
- Trial name
- NCT00384683
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Weaning Failure, Sepsis
Ultrasound-Assessed Diaphragmatic Dysfunction as a Predictor of Weaning Outcome
This study aims to assess whether the degree of diaphragm excursion and diaphragm thickening measured by ultrasound during a weaning trial may be used to predict successful weaning from mechanical ventilation in patients with…
- Trial name
- NCT04825509
- Testing
- Ultrasound
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Surgical Wound Infection, Heart; Surgery, Heart, Functional Disturbance as Result
Early Detection of Surgical Wound Infections Using Sensor Technology
Infections that are caused by surgical incision are commonly known as surgical site infections (SSI). A surgical wound infection can develop at any time after surgery until the wound has healed (usually two to three weeks after…
- Trial name
- SSI-Sensor (NCT03401658)
- Testing
- Sensor light detector
- Where
- United Kingdom
- Sponsor
- Liverpool Heart and Chest Hospital NHS Foundation Trust
Heart; Surgery, Heart, Functional Disturbance as Result
Monitoring of Cardiac Function With 3-axis Accelerometers
Aim of the study: To validate accelerometers for continuous monitoring of global cardiac function during weaning from cardiopulmonary bypass (CPB) in cardiac surgery.
- Trial name
- NCT01926067
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Oslo University Hospital