Clinical trials: Functional Dysphagia
Dysphagia, Swallowing Disorder
The Effects of Bilateral Cerebellar rTMS on Cortical Function
Swallowing function is controlled by two swallowing centres (one on each half of the brain). There is a dominant and non-dominant swallowing centre.
- Trial name
- NCT03831789
- Testing
- Cerebellar targeted rTMS
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Parkinsons Disease (PD), Oropharyngeal Dysphagia
Biological Determinants and Neural Compensation of Dysphagia in Parkinson's Disease
Parkinson's disease (PD) is the second most common neurodegenerative disorder and frequently leads to oropharyngeal dysphagia, a swallowing disorder that strongly affects patient health and quality of life.
- Trial name
- NCT07299448
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Irritable Bowel Syndrome, Gallstone Disease
Pharmacokinetics, Bioequivalence, and Safety Study of Trimedat® 76,95 mg Orally Disintegrating Tablets and Trimedat® 100 mg Tablets in Healthy Volunteers.
This study aims to evaluate pharmacokinetic profile, safety and establish bioequivalence of the investigational drug Trimedat® 76,95 mg orally disintegrating tablets compared to the reference drug Trimedat® 100 mg tablets in…
- Conditions
- Irritable Bowel Syndrome, Gallstone Disease, GERD, Biliary Dyskinesia
- Trial name
- NCT07421011
- Testing
- Trimedat®
- Where
- Russia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Valenta Pharm JSC
Spinal Cord Injuries, Deglutition Disorders
Respiratory Capacity and Swallowing Function in Spinal Disorders: A Pilot Study
This study is part of a larger grant, for which the overall goal is to collect measurements of liquid flow through the oropharynx (i.e., mouth and throat) during swallowing.The focus of this study is to evaluate the flow of…
- Trial name
- NCT04114604
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University Health Network, Toronto
Multiple Sclerosis, Dysphagia
Effects of CTAR and PNF Exercises on Swallowing in Multiple Sclerosis
This study compares two exercise programs for people with multiple sclerosis (MS) who have trouble swallowing. One group did chin exercises against resistance (CTAR), and the other group did neck exercises based on a technique…
- Conditions
- Multiple Sclerosis, Dysphagia, Deglutition Disorders
- Trial name
- CTAR-PNF-MS (NCT07726667)
- Testing
- CTAR exercise, PNF exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Sanko University
Thyroidectomy, Voice Alteration
Impact of Total Thyroidectomy on Voice and Swallowing
Purpose of this study is to evaluate the outcome of total thyroidectomy on vocal and swallowing function.
- Conditions
- Thyroidectomy, Voice Alteration, Swallowing Alteration
- Trial name
- NCT01607242
- Testing
- Endoscopy of larynx, Voice Handicap Index, Swallowing Assesment
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- University of Thessaly
Obesity, Morbid, GERD
Functional Changes in the Stomach and Esophagus After One Anastomosis Gastric Bypass- OAGB
Evaluation of the functional changes in the stomach and esophagus of patients undergoing One Anastomosis Gastric Bypass (OAGB)
- Conditions
- Obesity, Morbid, GERD, Ulcer, Gastric
- Trial name
- BiFLux (NCT04422405)
- Testing
- One Anastomosis Gastric Bypass (OAGB)
- Where
- Switzerland
- Volunteers
- 300 people
- Sponsor
- Spital Limmattal Schlieren
Dysphagia
Effect of Direct Chin-tuck Against Resistance on Swallowing Function
Chin-tuck Against Resistance (CTAR) is a widely used training method in swallowing rehabilitation that strengthens the suprahyoid muscles, enhancing their contraction during swallowing and promoting the anterior-superior movement…
- Trial name
- NCT07479680
- Testing
- dCTAR
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Swallowing Function
Dysphagia in Head and Neck Cancer With Radiation
This study focuses on swallowing dysfunction, a common issue affecting 60-75% of head and neck cancer patients due to tumor damage, treatment complications, and chemoradiotherapy side effects, which can lead to malnutrition and…
- Trial name
- NCT06747208
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Dysphagia, Swallowing Function, Diet Modification, Dysphagia Diet, Diet Standardization
Standardized Dysphagia Diet in Clinical Evaluation of Swallowing Function
Diet modification has been a vital component in the management of dysphagia. The lingual manipulation of bolus, pharyngeal propulsion, and initiation of swallowing reflex are all affected by the texture of bolus.
- Trial name
- NCT05634980
- Testing
- FEES
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Sarcopenia, Dysphagia
Comparison of the Swallowing Functions in Sarcopenia and Dynapenia
The purpose of the study to investigate the comparison of the swallowing functions of the sarcopenia and dynapenia in older patients
- Conditions
- Sarcopenia, Dysphagia, Swallowing Disorder
- Trial name
- NCT04960007
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Deglutition Disorder, High Risk Pregnancy
Study of Fetal Swallowing
This study will establish a database of fetal movements associated with feeding. It will use information obtained from standard fetal ultrasound procedures to identify and measure the growth of the baby's face, lips, tongue, jaw…
- Trial name
- NCT00004566
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Swallowing Disorder
The Effect of Active Breathing Exercises for Elderly People in the Community
The goal of this clinical trial is to explore the impact of Active Breathing Exercises on swallowing function and quality of life in community-dwelling elderly individuals (≥60 year old) with swallowing disorders.
- Trial name
- ABE (NCT06232031)
- Testing
- Active Breathing Exercises
- Sponsor
- Zeng Changhao
Head and Neck Cancer, Swallowing Disorder
İnvestigation of the Effect of Neck Endurance on Swallowing and Directional Coordination in Head and Neck Cancer Patients
In the study, it was aimed to evaluate the relationship between dysphagia, which is one of the treatment complications, and the variables of respiratory performance, intraoral pressure and neck endura, and to look at the future…
- Conditions
- Head and Neck Cancer, Swallowing Disorder, Respiratory Function, Neck Muscle Issue
- Trial name
- NCT07434245
- Testing
- Fiberoptic Endoscopic Evaluate Swallowing
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Istanbul Arel University
Gastroesophageal Reflux Disease (GERD), Eosinophilic Esophagitis (EoE)
Mucosal Impedance in Pediatric Population
Our hypothesis is that patients with GERD and/or Eosinophilic Esophagitis (EE) have lower esophageal impedance measurements when compared to patients who do not have GERD or EE.
- Conditions
- Gastroesophageal Reflux Disease (GERD), Eosinophilic Esophagitis (EoE), Functional Dyspepsia
- Trial name
- NCT02320981
- Testing
- Standard of Care esophagogastroduodenoscopy (EGD) with measurement of mucosal impedance
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Dysphagia
Effects of IOPI on Swallowing Function and Functional Status in Geriatric Patients
This project is an exploratory study that aims to investigate the effects of IOPI therapy on the swallowing function and tongue strength of geriatric patients in a geriatric ward in an acute hospital.
- Trial name
- NCT05074784
- Testing
- IOPI Therapy, Tongue Depressor Traditional Intervention
- Volunteers
- 84 people
- Sponsor
- Khoo Teck Puat Hospital
Irritable Bowel Syndrome, Gastro-oesophageal Reflux Disease
The Influence of Concomitant Irritable Bowel Syndrome on Gastro-Oesophageal Reflux Disease Symptoms and Severity.
This research aims to investigate whether there is a link between irritable bowel syndrome (IBS) and acid reflux, particularly whether there is a difference in acid reflux symptoms between people with and without IBS.
- Trial name
- NCT06615856
- Testing
- Questionnaire
- Volunteers
- 124 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Oral Dryness and Saliva Altered, Oral Manifestations
The Effects of Using Augmented Reality (AR) System to Train Foreign Care Workers.
The aim of this study was to evaluate the effect of augmented reality (AR) system training intervention of foreign care workers on the salivary biomarker and oral function of older people.
- Conditions
- Oral Dryness and Saliva Altered, Oral Manifestations, Swallowing Disorder
- Trial name
- NCT05938166
- Testing
- oral care augmented reality (AR), video-based oral hygiene education course
- Where
- Taiwan
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Dyspepsia
The Safety and Efficacy of Dexloxiglumide for the Relief of Symptoms of Functional Dyspepsia.
"Functional dyspepsia" has been defined loosely as "pain or discomfort centered in the upper abdomen." The symptoms can also include fullness, early satiety, bloating, belching, nausea, retching and vomiting.
- Trial name
- NCT00303264
- Testing
- dexloxiglumide, Nexium (esomeprazole)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Forest Laboratories
Acute Stroke, Dysphagia
The Effects of Chin Tuck Against Resistance Exercise on Acute Stroke Patients With Dysphagia
The aim of this study is to investigate the effects of chin tuck against resistance exercise on swallowing function, depression, and quality of life in acute stroke patients with dysphagia.
- Trial name
- NCT06674356
- Testing
- chin tuck against resistance exercise
- Where
- Taiwan
- Volunteers
- 74 people
- Sponsor
- National Taiwan University Hospital