Clinical trials: Functional Immune Response
T Cell Response to Dried Plum, Vitamin D Influence on Immune Response
Prebiotics (Dried Plum) and Immune Function in Postmenopausal Women
Prior studies have shown that dietary supplementation with dried plums (also known as prunes) reduces bone loss in postmenopausal women.
- Conditions
- T Cell Response to Dried Plum, Vitamin D Influence on Immune Response, Dried Plum and Immune Function
- Trial name
- NCT07222111
- Testing
- Dried plums
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Indiana University
Immune Response
LIFEHOUSE: Description of the Tent Bucket -Immune Support
This immune support program will be an extension to the existing LIFEHOUSE program. Essential employees in Gig Harbor, WA; Colonial Heights, VA; Lenexa, KS, and Santa Fe Springs, CA, will be offered complimentary supplementation…
- Trial name
- LIFEHOUSE (NCT04734288)
- Testing
- Vit.D3 5000 IU, Immune Active
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Metagenics, Inc.
Immune Function, Immunity
Effects of TM02® Supplementation on Immune Function in Children
This randomized, double-blind, placebo-controlled clinical study evaluated the effects of 12 weeks of TM02® supplementation on immune-related outcomes in generally healthy children aged 2 to 12 years.
- Trial name
- NCT07853573
- Testing
- TM02®
- Where
- Malaysia
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Ligno Biotech Sdn. Bhd.
Cell Migration, Cell Invasion
This Repeated Measures Parallel-group Investigation Will Examine the Influence of Short-term Melatonin Supplementation (5mg, 3 x Day for 72 Hours) on Cellular Responses, Functional Performance and Recovery Following an Acute Bout of Dynamic Resistance Exercise in Resistance Trained Men and Women
Oral Melatonin is a commercially available product available alone and as a constituent in a number of supplements. Previous research suggests that short-term supplementation with oral melatonin may amplify the recovery response…
- Conditions
- Cell Migration, Cell Invasion, Exercise Recovery
- Trial name
- NCT06617351
- Testing
- Melatonin
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Yogurt Intake, Gastrointestinal Immune Function
Yogurt and GI Health
The purpose of this research is to assess mucosal immune function responses in the gastrointestinal (GI) tract to twice-daily yogurt consumption.
- Conditions
- Yogurt Intake, Gastrointestinal Immune Function, Gut Microbiome, Gut Health
- Trial name
- NCT05931471
- Testing
- Yogurt Intervention
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Irritable Bowel Syndrome
Manipulation of Visceral Sensitivity and Immune System in IBS
Irritable bowel syndrome (IBS) is a common condition. At least 20% of the population suffer from IBS. The symptoms of abdominal pain, diarrhoea, constipation, bloating and difficulty with bowel motions are often disabling.
- Trial name
- NCT00418340
- Testing
- probiotic (bacterial/dietary supplement)
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- London North West Healthcare NHS Trust
Constipation - Functional
Breath Gases, Gut Flora, and Immunity in Children With Constipation
Constipation is a common problem in children that can affect their daily life, school performance, and social activities. Researchers have found that the bacteria living in our intestines (called "gut microbiome") may play an…
- Trial name
- NCT07797491
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Crohn's Disease
Acupuncture Treatment for Active Crohn's Disease
The purpose of this study is to observe the efficacy and safety of acupuncture and moxibustion for Crohn's disease and the regulation mechanism of intestinal microbiota and peripheral immunity.
- Trial name
- NCT02559037
- Testing
- Acupuncture and moxibustion
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Shanghai Institute of Acupuncture, Moxibustion and Meridian
Over the Age of 65, Admitted to the Trauma Service
Immunologic Function in the Elderly After Injury
The purpose of this research is to learn more about the function of the body's ability to fight infection when the immune response is activated when injury occurs, in the elderly population.
- Trial name
- NCT00447135
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Summa Health System
Chronic Lymphocytic Leukemia (CLL)
The Duration of Humoral Immunity and the Memory Cell Function After Vaccination With 7-valent Pneumococcal Conjugate Vaccine in CLL
Patients with chronic lymphocytic leukemia (CLL)have had very poor humoral responses to pneumococcal polysaccharide vaccine (PPV).
- Trial name
- KLL2 (NCT00919321)
- Testing
- Pneumococcal polysaccharide vaccine (PPV)
- Where
- Finland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Vascular Function, Healthy
Effects of Sodium Chloride or Its Substitute Salt Potassium Chloride on Vascular Function
This is a prospective, monocentric, randomized trial to investigate how sodium chloride or its substitute potassium chloride acutely affects vascular function by ingestion via a salted soup.
- Conditions
- Vascular Function, Healthy, Diabetes
- Trial name
- ESCAPE-SALT (NCT05970601)
- Testing
- Soup
- Where
- Germany
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. med. Johannes Stegbauer
Type 1 Diabetes Mellitus
The Effect of Cocoa Flavanol on the BOLD Response and Cognitive Function in Type 1 Diabetes
Type 1 Diabetes (T1D) is associated with microvascular changes in the brain, which can cause cognitive dysfunction. Cocoa flavanols (CF) can stimulate vasodilation, resulting in enhanced cerebral blood flow and better cognitive…
- Trial name
- NCT03452605
- Testing
- cocoa flavanol supplementation
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Chronic Myeloproliferative Disorders, Leukemia
Measuring Changes in Blood in Patients at High Risk of Cytomegalovirus Infection After Undergoing Donor Bone Marrow Transplant or Peripheral Blood Stem Cell Transplant
RATIONALE: Tests that measure certain changes in blood in patients at high risk of cytomegalovirus infection may help doctors learn more about predicting cytomegalovirus infection after donor stem cell transplant.
- Conditions
- Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm
- Trial name
- NCT00716911
- Testing
- ganciclovir, polymerase chain reaction, flow cytometry
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Inflammation, Psychosocial Functioning
Mindfulness Meditation Neuroimaging Study for Undergraduates
This study is designed to test the effectiveness of mindfulness meditation intervention classes on psychosocial health outcomes.
- Conditions
- Inflammation, Psychosocial Functioning, Depression, Anxiety
- Trial name
- NCT05304052
- Testing
- Mindfulness Meditation classes
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Functional Immune Response, Postprandial Bioavailability DHA
The Effect of Algae Oil Supplements on Functional Immune Response and Bioavailability of Lipids in Blood, a Pilot Study
In this explorative study we will investigate whether two sustainable oil supplements yield equivalent results to fish oil supplements in terms of postprandial immune response, among elderly adults, after standardization of the…
- Conditions
- Functional Immune Response, Postprandial Bioavailability DHA, Fatty Acid Metabolism
- Trial name
- ALG (NCT07086573)
- Testing
- Algae oil 1, Algae oil 2, Fish oil (control)
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Maartje van den Belt
Arthritis, Rheumatoid, Muscular Weakness
Neuromusuclar Adaptations in the Rheumatoid Arthritis Disease
Rheumatoid arthritis (RA) is a chronic autoimmune disease that causes joint inflammation and progressive joint destruction. Rheumatoid cachexia is one of the structural manifestations of RA, and consists of a reduction in muscle…
- Trial name
- NCT03543488
- Testing
- Neuromuscular and functional capacity tests
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Somatoform Disorders, Fibromyalgia
Immune Patterns in Pain Patients DSM-IV
The purpose of this study is to define subgroups of patients with somatoform disorders due to DSM-IV by immunological, psychological and genetic characterization.
- Conditions
- Somatoform Disorders, Fibromyalgia, Myofascial Pain Syndrome, Diffuse, Depression
- Trial name
- IPPPDIV (NCT01106339)
- Where
- Germany
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Healthy
T Cell Responses to Various Levels of Exercise Stress
The objective of this project is to quantify the immunoendocrine response to acute stress events combining both physical and psychological challenges.
- Trial name
- NCT06638684
- Testing
- Exercise
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Kansas
Inflammatory Response, Metabolic Disturbance
Beet Supplementation, Exercise, Inflammation
This study will determine if ingesting a beet-based supplement with nitrates for 2 weeks moderates exercise-induced inflammation.
- Conditions
- Inflammatory Response, Metabolic Disturbance, Immune Suppression
- Trial name
- NCT05907135
- Testing
- Beet
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Gut Microbiota, Immune Function
The Effect of a Prebiotic, Probiotic and Synbiotic on the Gut Microbiota and Immune Response of Older Volunteers (GOS)
Healthy older volunteers will be recruited to a study where they will be given four different treatments over a 28 week period. These treatments include: a prebiotic, a probiotic, a synbiotic (prebiotic + probiotic) and a…
- Trial name
- NCT01586247
- Testing
- Synbiotic, Prebiotic, Probiotic
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Reading