Clinical trials: Functional Independence, open to volunteers
Duchenne Muscular Dystrophy (DMD)
The Effect of Dual-tasking Program on Cognitive and Physical Functions and Independence in Activities of Daily Living in Children With Duchenne Muscular Dystrophy: A Single-blind Randomized Controlled Trial
Duchenne Muscular Dystrophy (DMD) is an X-linked recessive disorder characterized by progressive muscle degeneration and frequent developmental, cognitive and behavioral impairments, occurring in one in 5000 live births of boys.
- Trial name
- DMD-DUAL-FUNC (NCT06887491)
- Testing
- Conventional physiotherapy program, Conventional physiotherapy program + Dual task program
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people
- Sponsor
- Lokman Hekim University
Mild Cognitive Impairment
Evaluation of a Digital Neurorehabilitation Program Using Exergames for Adults With Mild Cognitive Impairment
The goal of this clinical trial is to learn whether a semi-autonomous digital telerehabilitation program using therapeutic video games ("exergames") can help improve quality of life and functional independence in older adults…
- Trial name
- NCT07423260
- Testing
- Digital exergame-based neurorehabilitation program, Individual conventional physiotherapy
- Where
- Spain
- Volunteers
- 38 people
- Sponsor
- European University of Madrid
Stroke (Subacute)
Comparative Effects of Functional Electrical Stimulation and Mirror Therapy for Foot Clearance Among Patients With Sub-acute Stroke
This study aims to evaluate the effectiveness of two rehabilitation techniques- Functional Electrical Stimulation (FES) and Mirror Therapy (MT)-in improving motor recovery among stroke survivors.
- Trial name
- FES MT CVA (NCT07448532)
- Testing
- Neuromodulators, Sensory Agumentation
- Where
- 2 sites in Pakistan
- Volunteers
- 38 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Cerebral Palsy, Spastic Diplegia
Effects of Proprioceptive Neuromuscular Facilitation and Task-Oriented Training on Upper Extremity Function in Children With Spastic Diplegic Cerebral Palsy
Children with spastic diplegic cerebral palsy often experience upper extremity impairments, including reduced coordination, muscle control, and functional hand use, which limit independence in daily activities.
- Trial name
- PNF-TOT-CP (NCT07694804)
- Testing
- Proprioceptive Neuromuscular Facilitation (PNF), Task-Oriented Training (TOT), Combined Proprioceptive Neuromuscular Facilitation and Task-Oriented Training
- Where
- Pakistan
- Volunteers
- 63 people
- Sponsor
- Ibadat International University, Islamabad
Stroke
Effects of Group Leisure Activities and Musical Training on Hospital Stroke Rehabilitation.
The goal of this clinical trial is to learn whether adding group leisure activities and musical training can help people recover better after a stroke during their hospital rehabilitation.
- Trial name
- RehArt (NCT07541560)
- Testing
- Standard Intensive Stroke Rehabilitation Program, Music-supported Therapy, Enriched Intervention
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Escola Universitària d'Infermeria i Teràpia Ocupacional de Terrassa
Parkinson's Disease (PD)
Effects Of Strategy Training And PNF On Balance, Gait, And Independence In Parkinson's Disease
This randomized controlled trial aims to compare the effects of Strategy Training and Proprioceptive Neuromuscular Facilitation (PNF) on balance, gait, and functional independence in patients with Parkinson's disease.
- Trial name
- NCT07484451
- Testing
- PNF Technique, Strategy Training
- Where
- 2 sites in Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Mobility Limitation, Cognitive Impairment
Living Independence Through Functional Training
The purpose of the research is to evaluate the feasibility and benefits of a six-week hybrid task-oriented resistance exercise program for older adults who have been recently discharged from home health care.
- Trial name
- LIFT (NCT07125378)
- Testing
- Task-oriented resistance exercise
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- University of Florida
Memory Disorders
Predictive Factors of Autonomy Loss in Real-life Cohort
The Alzheimer's disease or related disorders (ADRD) are among the most disabling diseases because of their main features such as cognitive impairment, loss of functional autonomy and behavioural disorders.
- Trial name
- MEM-AURA (NCT03894254)
- Testing
- no intervention
- Where
- 5 sites in France
- Volunteers
- 5,400 people
- Sponsor
- Hospices Civils de Lyon
Stroke
Thoracolumbar Fascia Thickness in Chronic Stroke Patients
The main objective of this study was to examine the thoracolumbar fascia thickness in chronic stroke patients using objective methods and to reveal the relationship of this flexibility with balance, trunk control, trunk…
- Trial name
- NCT07107295
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ankara University
Neurofibromatosis 1 (NF1), Executive Function (Cognition)
Cognitive Intervention for Children and Adolescents With NF1
Psychological interventions have been shown to be effective for managing cognitive and mental health challenges in different patient populations.
- Conditions
- Neurofibromatosis 1 (NF1), Executive Function (Cognition), Cognitive Intervention
- Trial name
- NCT07869914
- Testing
- Unstuck and On Target!
- Volunteers
- 60 people
- Sponsor
- The Hospital for Sick Children
Chronic Stroke Patients
Neuropilates and Otago Exercises on Balance, Posture and Functional Independence in Chronic Stroke
This randomized clinical trial will be conducted at various physical therapy clinics of Faisalabad over a six-month period, enrolling a total of 32 participants selected through non probability convenience sampling technique.
- Trial name
- NCT07293416
- Testing
- neuropilates, otago exercises
- Where
- 3 sites in Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Stroke
Effect of MRP With and Without EMS on Gait, Functional Independence and QOL in Stroke Patients
To determine the effects of motor relearning programme with and without electrical muscle stimulation on gait, functional independence and quality of life in hemiplegic stroke patients.
- Trial name
- NCT06407830
- Testing
- motor relearning programme, electrical muscle stimulations with motor relearning programme
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Riphah International University
Functional Neurological Disorder, Conversion Disorder
Restoring Independence With Stimulation-Enhanced Treatment for People With Functional Neurological Disorder
The goal of this clinical trial is to test a new treatment for adults with walking problems due to Functional Neurological Disorder (FND).
- Trial name
- RISE-FND (NCT07769970)
- Testing
- Stimulation-Enhanced Physical Therapy, Active Comparator
- Where
- New Zealand
- Volunteers
- 60 people
- Sponsor
- University of Auckland, New Zealand
Acute Burns
Non-Invasive Vagus Nerve Stimulation in Patients With Acute Burn Injuries
This randomized controlled study will investigate the effects of non-invasive vagus nerve stimulation on inflammatory response and functional recovery in adults with acute burn injuries.
- Trial name
- NCT07574580
- Testing
- Non-Invasive Auricular Vagus Nerve Stimulation, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Fenerbahce University
Healthy Elderly
Innovative Hand Rehabilitation System With Synchronized Contralateral Haptic Feedback
Previous studies have found that graded motor imagery (GMI) training can provide continuous activation of the cerebral cortex compared to traditional rehabilitation therapy.
- Trial name
- NCT07077460
- Testing
- TIPr, Mirror Visual Feedback Device, Mirror Visual Feedback Device(Blocked mirror)
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Immune Deficiency
Efficacy of QBKPN Site-Specific Immunomodulator in Improving Innate Immune Function & Reducing Respiratory Tract Infection in Older Adults
This study is designed to test whether QBKPN SSI can improve immune function in older adults, including how well it can protect against respiratory and other infections, whether it improves the body's response to COVID-19…
- Trial name
- RESILIENCE (NCT05421325)
- Testing
- QBKPN SSI
- Where
- Canada
- Volunteers
- 72 people
- Sponsor
- Qu Biologics Inc.
Immunometabolism, Mitochondrial Function, Bioenergetics
Independent and Combined Effects of Short-term Sulforaphane Supplementation and Exercise on Immunometabolism in Healthy Adults
The study consist of 3 interventional periods which will be completed by each consenting participant in a randomized, crossover fashion. The interventional periods will be separated by a minimum 1 week washout period.
- Conditions
- Immunometabolism, Mitochondrial Function, Bioenergetics, Inflammation
- Trial name
- EXSFN (NCT07668596)
- Testing
- Sulforaphane-rich Broccoli Sprout Extract, High Intensity Interval Treadmill Running
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Parkinson Disease (PD)
Idiopathic Parkinson's Disease: Interest of an Early Group-Based Cognitive Rehabilitation Program (LIFECOG-PD)
Current pharmacological treatments have not demonstrated significant improvement in cognitive impairment in Parkinson's disease (PD).
- Trial name
- LIFECOG-PD (NCT07813156)
- Testing
- cognitive rehabilitation program
- Where
- France
- Volunteers
- 24 people
- Sponsor
- University Hospital, Clermont-Ferrand
Intrinsic Capacity, Frailty
Project ICOPE Brazil: Assessment of Intrinsic Capacity in Brazilian Older Adults
The ICOPE Brazil study aims to understand aging trajectories in Brazil, especially healthy aging trends based on intrinsic capacity, a collective of mental and physical capacities one may have to maintain their functional ability…
- Conditions
- Intrinsic Capacity, Frailty, Aging, Healthy Aging
- Trial name
- ICOPE-BR (NCT06968702)
- Volunteers
- 3,838 people
- Sponsor
- University of Sao Paulo
Stroke, Ideomotor Apraxia
Post-Stroke Apraxia, Motor Function, Balance, and Gait
The goal of this observational study is to examine whether ideomotor apraxia is associated with motor function, balance, walking performance, and independence in daily activities in adults with hemiplegia after stroke.
- Conditions
- Stroke, Ideomotor Apraxia, Hemiplegia
- Trial name
- NCT07879807
- Testing
- Standardized clinical assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Izmir City Hospital