Clinical trials: Functional Independence
Independent Living, Disability Free Survival
A Clinical Trial of STAtin Therapy for Reducing Events in the Elderly (STAREE)
The STAREE study will examine whether treatment with statin (atorvastatin 40mg) compared with placebo will prolong disability free survival and reduce major cardiovascular events amongst healthy elderly people (≥70 years).
- Conditions
- Independent Living, Disability Free Survival, Elderly, Healthy
- Trial name
- STAREE (NCT02099123)
- Testing
- Atorvastatin
- Where
- 6 sites in Australia
- Volunteers
- 9,971 people, healthy volunteers welcome
- Sponsor
- Monash University
Spinal Cord Injury (SCI)
Trunk Balance and Functional Independence in Individuals With SCI
This study investigates the relationship between trunk balance, position sense, wheelchair skills, and functional independence in individuals with thoracic spinal cord injury.
- Trial name
- SCI (NCT06612112)
- Testing
- No Interventions
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Afyonkarahisar Health Sciences University
Mobility Limitations, Malnutrition
Older Person's Exercise and Nutrition Study
The novelty with the OPEN study is to evaluate the effects of the simple sit-to-stand exercise during routine care, in combination with an oral protein-rich supplement, on functional status and independence in frail older…
- Trial name
- OPEN (NCT02702037)
- Testing
- oral protein-rich supplement, Exercise
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Karolinska Institutet
Osteoarthritis
Determinants of Functional Ability, Perceived Health, and Interaction With Multimorbidity in Hip and Knee Osteoarthritis
Hip and knee osteoarthritis (OA) is an important health problem with a high prevalence and significant consequences on functional ability, perceived health, restriction of autonomy and handicap.
- Trial name
- PRO-ART (NCT02887092)
- Volunteers
- 881 people
- Sponsor
- Central Hospital, Nancy, France
Multiple Sclerosis, Rehabilitation
Robot-assisted Arm Training in Multiple Sclerosis
The upper limb (UL) plays an important role in the daily functioning of patients with Multiple Sclerosis (MS) and negatively influences their quality of life. Effective arm-hand training programs are needed.
- Trial name
- RAMSES (NCT03561155)
- Testing
- Robot assisted treatment (Amadeo®), Conventional treatment
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Early Ambulation
Implementing a Hospital-Based Walking Program (STRIDE): Function QUERI 2.0
Implementing a Hospital-Based Walking Program (STRIDE): Function QUERI 2.0 aims to compare implementation strategies for large-scale spread of STRIDE, a supervised walking program for hospitalized older Veterans.
- Trial name
- STRIDE (NCT04868656)
- Testing
- Implementation Strategy: Foundational Support, Implementation Strategy: Enhanced Support
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- VA Office of Research and Development
Pain, Pruritus
Desensitization of Nociceptive Afferents by Application of Topical Capsaicin, Trans-cinnamaldehyde and L-menthol
The purpose of this study is to investigate the potential desensitising effects of repeated applications of capsaicin, trans-cinnamaldehyde and L-menthol on thermal, mechanical and chemical sensory stimulations.
- Conditions
- Pain, Pruritus, Neuropathic Pain, Dermatology/Skin - Other
- Trial name
- NCT03132142
- Testing
- Capsaicin, Trans-cinnamaldehyde, L-Menthol
- Where
- Denmark
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Dementia, Alzheimer's Disease
Preventing Loss of Independence Through Exercise (PLIE) in Persons With Dementia
Nearly 1 in 10 older Veterans have dementia, which is a devastating condition that leads to a progressive loss of independence and functional status. Currently available dementia medications do not alter the disease course.
- Trial name
- PLIE-VA (NCT02350127)
- Testing
- Preventing Loss of Independence through Exercise (PLIE), Usual Care
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- VA Office of Research and Development
Stroke
Remediation of the Non-Paretic Arm in Stroke
Stroke survivors with severe contralesional paresis often have substantial control and coordination deficits in the non-paretic arm.
- Trial name
- NCT03062930
- Testing
- Track 1, Track 2
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Milton S. Hershey Medical Center
Muscle, Ligament and Fascia Disorders
Muscle Strength and Functional Autonomy of Elderly Women
This study shows an evaluation of the correlation between the muscle strength levels and functional autonomy of elderly women.
- Trial name
- NCT01553396
- Volunteers
- 35 people
- Sponsor
- Euro-American Network of Human Kinetics
Spinal Cord Injuries
Kinesiophobia, Fear of Falling, Functional Independence, and Psychological Status in Spinal Cord Injury
Individuals aged 18-65 years who have been clinically diagnosed with spinal cord injury and have developed paraplegia will be included in the study.
- Trial name
- NCT07549217
- Volunteers
- 70 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Cerebral Palsy (CP), Balance
Sensory Integration Therapy and Function in Cerebral Palsy
Cerebral palsy (CP) is a non-progressive neurological disorder that affects movement, posture, and functional abilities. Children with CP frequently experience impairments in motor control, sensory processing, balance, postural…
- Conditions
- Cerebral Palsy (CP), Balance, Sensory Integration Disorder
- Trial name
- NCT07278635
- Testing
- Sensory Integration Therapy, Balance and Coordination Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Yeditepe University
Alzheimer's Disease, Dementia Disorders
Comparison of Two Modes of Administration of the IADL Questionnaire, Assessing the Level of Functional Autonomy of Patients to Carry Out the Tasks of Daily Living: Randomized Controlled Trial Among Patients of a Memory Clinic
In France, about 1 million people 65 and older are diagnosed with dementia syndrome characterized by cognitive decline and impairment of functional capacity.
- Trial name
- IADL (NCT02654574)
- Testing
- IADL administration by phone
- Where
- France
- Volunteers
- 299 people
- Sponsor
- Hospices Civils de Lyon
Mild Cognitive Impairment, Dementia
Exercise and Activities for Independent Living With Mild Cognitive Impairment (MCI)
The purpose of this project is to evaluate an exercise and health promotion program for older adults with mild memory loss. The study will investigate the efficacy of a memory-enhanced exercise and health promotion program to…
- Trial name
- NCT00446394
- Testing
- Resources and Activities for Life Long Independence (RALLI), Social Walking program (SW)
- Where
- United States
- Volunteers
- 181 people
- Sponsor
- University of Washington
Stroke
Effect of Gait Training With Auditory Stimuli on Balance, Gait & Funtional Independence in Stroke
To determine the effect of gait training with auditory stimuli on dynamic balance, gait and functional independence on chronic stroke.
- Trial name
- NCT05751161
- Testing
- conventional gait training
- Where
- Pakistan
- Volunteers
- 18 people
- Sponsor
- Riphah International University
Down Syndrome
Neurodevelopmental Treatment for Balance and Mobility in Children With Down Syndrome
The goal of this clinical trial is to evaluate whether Neurodevelopmental Treatment (NDT) can improve balance, mobility, walking capacity, and functional independence in preschool children with Down syndrome.
- Trial name
- NCT07653399
- Testing
- Neurodevelopmental Treatment (NDT)
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Istanbul Nisantasi University
Alzheimer Disease
Effects of Enriched Gardens in Nursing Home Residents With Dementia
Comparing the effect of the frequentation of an enriched garden vs sensory conventional garden by nursing home residents with Alzheimer disease.
- Trial name
- NCT04903171
- Testing
- INCENTIVE VISITING A GARDEN : ENRICHED OR CONVENTIONAL SENSORY GARDEN
- Where
- France
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- RIVAGES
Memory Disorders
Predictive Factors of Autonomy Loss in Real-life Cohort
The Alzheimer's disease or related disorders (ADRD) are among the most disabling diseases because of their main features such as cognitive impairment, loss of functional autonomy and behavioural disorders.
- Trial name
- MEM-AURA (NCT03894254)
- Testing
- no intervention
- Where
- 5 sites in France
- Volunteers
- 5,400 people
- Sponsor
- Hospices Civils de Lyon
Adolescent Behavior, Psychosocial Functioning
Intervention to Enhance Coping and Help-seeking Among Youth in Foster Care
This study will deploy a scalable secondary prevention program that leverages existing foster youth transition services to improve mental health functioning and service use before and after exiting foster care.
- Conditions
- Adolescent Behavior, Psychosocial Functioning, Coping Behavior, Help-Seeking Behavior
- Trial name
- NCT06019377
- Testing
- Stronger Youth Networks and Coping (SYNC)
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Portland State University
Hemiplegic Cerebral Palsy
Effect of Action Observation Physical Training on Quality of Upper Limb and Functional Independence in Children With Hemiplegia
30 children with a diagnosis of hemiplegic cerebral palsy
- Trial name
- AOPT (NCT05875012)
- Testing
- action observation physical training, Traditional physical therapy training
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University