Clinical trials: Functional Knee Pain
Knee Osteoarthristis
Femoral Nerve Mobilization for Patients With Knee Osteoarthritis
Background: Knee osteoarthritis (KO) is considered as a cause of disability among the elderly, causing pain, reduced quality of life, and decreased functionality.
- Trial name
- RCT (NCT07329205)
- Testing
- traditional physical therapy, Femoral nerve mobilization
- Where
- Saudi Arabia
- Volunteers
- 50 people
- Sponsor
- Prince Sattam Bin Abdulaziz University
Knee Osteoarthritis, Chronic Knee Pain
Selective Nerve Ablation for Chronic Knee Pain: A Retrospective Study
SAVE-KNEE is a single-center retrospective observational cohort study evaluating outcomes of ultrasound-guided cryoneurolysis, radiofrequency ablation and chemical neurolysis for chronic knee pain in routine clinical care.
- Trial name
- SAVE-KNEE (NCT07835672)
- Testing
- Ultrasound-Guided Cryoneurolysis, Ultrasound-Guided Radiofrequency Ablation, Ultrasound-Guided Chemical Neurolysis
- Where
- Poland
- Volunteers
- 746 people
- Sponsor
- Michał Bartoszewicz
Knee Osteoarthristis
BFR Training and Knee Osteoarthritis
Knee osteoarthritis (KOA) is a chronic, progressive degenerative joint disease characterized by cartilage and bone degeneration, synovial inflammation, and structural changes.
- Trial name
- NCT07590323
- Testing
- Standard Treatment, Pain neuroscience education, Blood flow restriction training
- Where
- Saudi Arabia
- Volunteers
- 90 people
- Sponsor
- University of Hail
Total Knee Arthroplasty
Femoral Triangle and Adductor Canal Blocks Versus Femoral Nerve Block for Total Knee Arthroplasty
This prospective, double-blinded, randomized controlled study evaluates effects of femoral triangle and adductor canal blocks in comparison with femoral nerve block for primary total knee arthroplasty.
- Trial name
- NCT03645954
- Testing
- Femoral Nerve Block, Femoral Triangle & Adductor Canal Blocks
- Where
- Lithuania
- Volunteers
- 80 people
- Sponsor
- Lithuanian University of Health Sciences
Osteoarthritis, Knee
Effect of Patellar Denervation on Post-operative Knee Pain and Knee Function in Total Knee Arthroplasty
This study is a double-blind randomized controlled trial aiming to investigate the effects of patellar denervation using electrocautery on postoperative knee pain and knee function in patients undergoing primary total knee…
- Trial name
- PD (NCT07342166)
- Testing
- Patellar Denervation
- Where
- Thailand
- Volunteers
- 64 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Knee Osteoarthritis, Central Pain Syndrome
Effects of Vagus Nerve Stimulation on Central Pain Sensitivity & Parasympathetic Function in Knee Osteoarthritis
The goal of this clinical trial is to test the feasibility and effectiveness of transcutaneous vagus nerve stimulation (tVNS) to the ear on pain and autonomic function in people with knee osteoarthritis (OA).
- Trial name
- NCT05625178
- Testing
- Transcutaneous vagus nerve stimulation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Texas, El Paso
Osteoarthritis of the Knee
Efficacy of Spearmint Tea in Relieving Osteoarthritis of the Knee
The purpose of this study is to investigate the benefits of daily consumption of a high rosmarinic acid spearmint tea, developed by the University of Guelph, on measures of pain, physical function and disease activity in…
- Trial name
- NCT01380015
- Testing
- Commercially spearmint tea, High Rosmarinic Acid Spearmint Tea
- Where
- 2 sites in Canada
- Volunteers
- 49 people
- Sponsor
- University of Guelph
Knee Osteoarthritis
Effects of Body Awareness Therapy in Knee Osteoarthritis
The aim of this study is to investigate the effect of Body Awareness Therapy (BAT) on pain, balance and functional capacity in patients with knee osteoarthritis.
- Trial name
- NCT04165187
- Testing
- Body Awareness Therapy, Home exercise program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bezmialem Vakif University
Osteoarthritis, Knee
Effects of Different Telerehabilitation Methods on Pain, Functional Limitation, Muscle Strength, Balance, and Quality of Life in Patients With Knee Osteoarthritis.
The aim of our study is; To compare the effectiveness of asynchronous and synchronous telerehabilitation programs on pain, functional limitation, muscle strength, balance and quality of life parameters in patients with knee…
- Trial name
- NCT05514704
- Testing
- Exercise Therapy via video conference, Exercise Therapy via mobile application
- Volunteers
- 60 people
- Sponsor
- Marmara University
Osteoarthritis, Knee
Effects of Neurodynamics of Pain and Function in Patients With Knee Osteoarthrosis
Osteoarthritis is defined as a degenerative joint disease characterised by a decrease in joint space due to cartilage loss and the presence of subchondral sclerosis and osteophytes.
- Trial name
- NCT05375448
- Testing
- Neural mobilisation
- Where
- 2 sites in Spain
- Volunteers
- 50 people
- Sponsor
- CEU San Pablo University
Knee Osteoarthritis
Effects of Nigella Sativa Oil on Pain Intensity and Physical Functions in Patients With Knee Osteoarthritis
Purpose: The study was conducted to determine the effect of 1 ml of nigella sativa oil applied for 2 minutes three times a day for 21 days on pain severity and physical functions in patients with knee osteoarthritis (OA).
- Trial name
- NCT05541185
- Testing
- Nigella sativa oil, Naproxen and lidocaine gel, Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Sultan ÇEÇEN
Primary Total Knee Arthroplasty
The Efficacy of Local Infiltration Analgesia for Postoperative Pain Management After Total Knee Arthroplasty
This prospective, double-blinded, randomized controlled study evaluates the effects of peripheral nerve blocks with and without local infiltration analgesia for postoperative pain management after primary total knee arthroplasty.
- Trial name
- NCT04258241
- Testing
- Local infiltration analgesia with local anesthetic, Local infiltration analgesia without local anesthetic, Needle
- Where
- Lithuania
- Volunteers
- 80 people
- Sponsor
- Lithuanian University of Health Sciences
Patello Femoral Pain Syndrome
Active Release and Myofascial Release Technique in Patients With Patellofemoral Pain Syndrome
Patellofemoral pain syndrome (PFPS) is often associated with imbalance and weakness in several key muscle group. These include the quadriceps (especially the vastus medialis oblique), hip abductors and external rotators and…
- Trial name
- NCT07854041
- Testing
- Group A, Group B
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Osteoarthritis, Pain
An Investigation Into the Role of Walking in Treating the Symptoms of Knee Osteoarthritis: The WalkOut Study
There are over 8.75 million people in the United Kingdom with osteoarthritis in their knees. The effect of this condition can be debilitating. Symptoms are due to wear and tear of the knee joint.
- Conditions
- Osteoarthritis, Pain, Arthritis, Gonarthritis
- Trial name
- WalkOut (NCT02748291)
- Testing
- Walking, Department of Health Physical Activity Guidelines
- Where
- United Kingdom
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Meniscus Injury, Kinesio Taping
Kinesiotaping in Isolated Meniscus Injuries
The effect of kinesiotaping on pain and functionality in isolated meniscus injuries.
- Trial name
- NCT07574307
- Testing
- Exercise, kinesiotaping
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Bandırma Onyedi Eylül University
Pain, Osteoarthritis, Hip
Placebo-controlled Trial With OROS Hydromorphone Hydrochloride to Treat Patients With Moderate to Severe Pain Induced by Osteoarthritis of the Hip or the Knee
This clinical trial tests the pain relieving effectiveness of OROS hydromorphone, a once-daily formulation of a strong opioid against placebo in patients, who are suffering from pain due to osteoarthritis of the hip or the knee…
- Conditions
- Pain, Osteoarthritis, Hip, Osteoarthritis, Knee
- Trial name
- NCT00980798
- Testing
- OROS hydromorphone HCl
- Where
- 12 sites in Czechia, Romania and 2 more
- Volunteers
- 288 people
- Sponsor
- Janssen-Cilag International NV
Knee Osteoarthritis, Pain, Musculoskeletal
Intra-articular Corticosteroid Injection in GAE for Knee Knee Osteoarthritis
The goal of this clinical trial is to investigate the effectiveness and safety of intra-articular corticosteroid injection (IACI) in alleviating post-procedural pain and improving early outcomes in patients undergoing geniculate…
- Trial name
- NCT06514716
- Testing
- Geniculate Artery Embolization with Intra-articular Corticosteroid Injection (GAE with IACI), Geniculate Artery Embolization alone (GAE alone)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Zagazig University
Patellofemoral Pain Syndrome
Comparison of Effects of Mobilization With Movement and Kinesiotaping in Patellofemoral Pain Syndrome
Patellofemoral Pain Syndrome (PFPS), also known as the anterior knee pain, is one of the most common musculoskeletal disorders. Most of the patients suffer from knee pain for long time.
- Trial name
- NCT02707679
- Testing
- Mulligan's Straight leg-raise with traction, Mulligan's Mobilization with Movement, Kinesiotaping
- Volunteers
- 35 people
- Sponsor
- Hacettepe University
Knee Osteoarthritis, Pain
Magnetotherapy Versus Microwave Combined With Exercise for Knee Osteoarthritis.
The high prevalence of knee osteoarthritis and the absence of well-defined protocols for the application of Magnetotherapy (MT), makes it necessary to investigate the effect of this therapy on patients with knee osteoarthritis.
- Trial name
- MT-MW-EX (NCT04866745)
- Testing
- Magnetotherapy plus exercise, Microwave plus exercise
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- University of Castilla-La Mancha
Knee Osteoarthritis
Effect of Retro Walking Versus Isometric Multi-angular Exercises on Pain and Functional Performance in Knee Osteoarthritis in Geriatric Population
Osteoarthritis is a leading musculoskeletal cause of disability in elderly persons all over the world and a major cause of physical limitations and reduced quality of life (1).
- Trial name
- NCT06274346
- Testing
- Multiangular Isometric exercise
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Delta University for Science and Technology