Clinical trials: Functional Limitation
Osteoarthritis, Knee
Effects of Different Telerehabilitation Methods on Pain, Functional Limitation, Muscle Strength, Balance, and Quality of Life in Patients With Knee Osteoarthritis.
The aim of our study is; To compare the effectiveness of asynchronous and synchronous telerehabilitation programs on pain, functional limitation, muscle strength, balance and quality of life parameters in patients with knee…
- Trial name
- NCT05514704
- Testing
- Exercise Therapy via video conference, Exercise Therapy via mobile application
- Volunteers
- 60 people
- Sponsor
- Marmara University
Relapsing Remitting Multiple Sclerosis, Secondary Progressive Multiple Sclerosis
Functional Outcomes From Diets in Multiple Sclerosis
The purpose of this study is to test the effects of two dietary interventions, glycemic load and calorie restriction, on physical function, cognition, pain, fatigue, mood, and anxiety in adults with multiple sclerosis (MS).
- Trial name
- FOOD_for_MS (NCT05327322)
- Testing
- Glycemic load, Calorie restriction, Behavioral support
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Alabama at Birmingham
Traumatic Brain Injury
The Brave Initiative: Bringing Rehabilitation to American Veterans in an Enriched Environment
The purpose of this study is to determine the value of Constraint-Induced Movement therapy (CIMT) for improving motor function and general fitness in adults with subacute and chronic traumatic brain injury (TBI), particularly TBI…
- Trial name
- TBI (NCT02339220)
- Testing
- Constraint-Induced Movement Therapy (CIMT), Lakeshore Enriched Fitness Training (LEFT), standard Transfer Package (sTP)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Alabama at Birmingham
Cerebral Palsy, Spastic
Effectiveness of Virtual Reality on Functional Mobility During Treadmill Training in Children With Cerebral Palsy
Cerebral palsy (CP), which occurs as a consequence of brain damage, has multiple deficits such as a global reduction of motor cortical activity during movement execution and inadequate processing of corticospinal and…
- Trial name
- NCT05131724
- Testing
- Treadmill training with virtual reality, Treadmill training
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- University of Vic - Central University of Catalonia
Pain, Stiffness
Use of Whole-Body Periodic Acceleration Therapy To Aches and Pains
The purpose of this study is to test the effectiveness of whole body periodic acceleration for helping with symptoms of aches and pains suffered by many patients.
- Conditions
- Pain, Stiffness, Abnormal Gait, Balance
- Trial name
- Exer-Rest (NCT01629810)
- Testing
- Whole body periodic acceleration (Exer-Rest)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Center for Translational Medicine
Metabolic Syndrome
Calorie Restricted Diet and Exercise
Calorie-restricted(CR) diet and exercise were effective to reduce Metabolic syndrome(MetS), however, its effect on knee functions for MetS patients with degenerate meniscus lesions(DMLs) was still poorly investigated.
- Trial name
- NCT05092178
- Testing
- calorie restricted diet and exercise, exercise alone
- Where
- China
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- The First People's Hospital of Jingzhou
Healthy Individuals
Acute Effects of Exercises Combined With Blood Flow Restriction in Healthy Individuals
Purpose of the study is; to investigate the acute effects of exercises combined with blood flow restriction on strength, proprioception and functional motor performance in healthy individuals.
- Trial name
- NCT04206345
- Testing
- exercise with blood flow restriction, exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Caloric Restriction, Body Composition
Short Term Effects of Semaglutide on Body Composition and Performance
Semaglutide, a GLP-1 receptor agonist, has demonstrated significant weight-loss effects in people with obesity and/or type 2 diabetes, but its impact on exercise performance among lean, fit athletes remains unknown.
- Conditions
- Caloric Restriction, Body Composition, Performance
- Trial name
- NCT07874971
- Testing
- Semaglutide (SEMA)
- Where
- Denmark
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Morten Hostrup, PhD
Muscle Strength, Athletic Performance
Nordic vs Blood Flow Restriction Nordic Exercise in Elite Female Pole Vaulters
The purpose of this randomized controlled trial is to compare the effects of Nordic Hamstring Exercise (NHE) and Blood Flow Restriction-assisted Nordic Hamstring Exercise (BFR-NHE) on hamstring muscle strength, muscle morphology…
- Conditions
- Muscle Strength, Athletic Performance, Hamstring Adaptation, Sports Injury Prevention
- Trial name
- NCT07705698
- Testing
- Nordic Hamstring Exercise, Blood Flow Restriction-Assisted Nordic Hamstring Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Toros University
Covid19, Dyspnea
Understanding Exertional Dyspnea and Exercise Intolerance in COVID-19
A novel corona virus emerged in 2019 causing Corona Virus Disease 2019 (covid-19). In one year more than 80 000 000 cases worldwide were documented.
- Trial name
- NCT04732663
- Testing
- No Intervention
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Chronic Obstructive Pulmonary Disease (COPD), Blood Flow Restriction Training (BFRT)
Effects Of Low-Load Blood Flow Restriction Training Of The Upper Extremity In Patients With Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease (COPD) is characterized by persistent airflow limitation, progressive dyspnea, and peripheral muscle dysfunction, significantly impairing functional capacity and quality of life.
- Trial name
- NCT07469111
- Testing
- Low-Load Blood Flow Restriction Training (LL-BFRT) + Aerobic Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Inonu University
Hand Transplantation, Peripheral Nerve Injuries
Harnessing Neuroplasticity to Enhance Functional Recovery During Chronic Recovery From Upper Extremity Nerve Repair
This study adopts a strategy that has arisen from basic neuroscience research on facilitating adaptive brain plasticity and applies this to rehabilitation to improve functional recovery in peripheral nervous system injuries…
- Conditions
- Hand Transplantation, Peripheral Nerve Injuries, Neurologic Rehabilitation
- Trial name
- NCT03610763
- Testing
- Transcranial Direct Current Stimulation, Modified Constraint Induced Movement Therapy
- Where
- 3 sites in United States
- Volunteers
- 180 people
- Sponsor
- University of Missouri-Columbia
Cerebral Palsy Spastic Hemiplegic
Investigation of the Effect of Constraint Induced Movement Therapy Applied to the Lower Extremity on Lower Extremity Functions in Individuals With Unilateral Cerebral Palsy
Lower extremity constraint induced movement therapy has been applied to individuals with multiple sclerosis, stroke, subacute and chronic hemiparesis in recent years and positive results have been reported.
- Trial name
- NCT06753812
- Testing
- constraint induced movement therapy, Control (Standard treatment)
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Abant Izzet Baysal University
Neonates and Preterm Infants, Neonates or Premature Babies
Prospective Study of the Feasibility of Brain Connectivity Imaging by Functional Ultrasound Imaging (fUS) in Newborn Infant
Neurodevelopmental disorders (NDD) affect how the brain develops and can lead to lifelong difficulties with movement, learning, behavior, and thinking.
- Trial name
- CONEXUS (NCT06940713)
- Testing
- Imaging Time
- Where
- France
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Phase I Randomized Controlled Trial of Functional Resistance Training in Older Cancer Survivors: The ACES Trial
The study will assess the feasibility and preliminary efficacy of live, online supervised group functional resistance training in older cancer survivors who may have difficulty with independent functioning.
- Conditions
- Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm, Cancer, Functional Limitation
- Trial name
- ACES (NCT07606313)
- Testing
- Functional Resistance Training, Stretching, Delayed Functional Resistance Training
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- OHSU Knight Cancer Institute
Anterior Cruciate Ligament Rupture
BFRT in Adolescents After ACL Reconstruction
This is an interventional study that will examine effects of blood flow restriction training (BFRT) in adolescents aged 12-18 after anterior cruciate ligament reconstruction surgery (ACLR).
- Trial name
- NCT04390035
- Testing
- Blood Flow Restriction using Delfi Personalized Tourniquet System
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Healthcare of Atlanta
HIV Infections, Cardiovascular Diseases
Implementation and Effectiveness of Physical Activity to Prevent Disability in HIV-infected Adults Older Than 50 From Côte d'Ivoire
The overall objective of this research is to provide evidence on the effectiveness and implementation of two strategies deliver a structured programme of physical activity (PA) people living with HIV older than 50 years from…
- Conditions
- HIV Infections, Cardiovascular Diseases, Insulin Resistance Syndrome X
- Trial name
- VIRAGE+ (NCT06139497)
- Testing
- Physical activity programme, Home-based physical activity
- Where
- 2 sites in Côte d’Ivoire
- Volunteers
- 180 people
- Sponsor
- ANRS, Emerging Infectious Diseases
Stroke, Upper Limb Motor Impairment
tDCS Combined With Constraint-Induced Therapy in Post-Stroke Upper Limb Rehabilitation
The objective of this clinical trial is to evaluate the effects of transcranial direct current stimulation (tDCS) combined with constraint-induced therapy (CIT) on upper limb motor recovery in individuals after stroke.
- Conditions
- Stroke, Upper Limb Motor Impairment, Post-Stroke Hemiparesis
- Trial name
- tDCS-CIT Strok (NCT07458503)
- Testing
- transcranial direct current stimulation (tDCS), Constraint-induced movement therapy
- Where
- 2 sites in Brazil
- Volunteers
- 40 people
- Sponsor
- Universidade do Estado do Pará
Aging, Cognitive Decline
Augmented Reality Treadmill Walking for Cognitive and Physical Health in Older Adults
This study evaluated the feasibility and health effects of using augmented reality (AR) treadmill walking in older adults. Sixty community-dwelling adults aged 65 to 80 years were randomly assigned to either an AR treadmill group…
- Conditions
- Aging, Cognitive Decline, Sarcopenia, Mobility Limitation
- Trial name
- ART-Walk (NCT07074613)
- Testing
- Traditional Treadmill Walking, JOHNSON 8.1T treadmill with Passport AR system
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan College of Performing Arts
Acute Renal Failure
Brief Title:Effect of a Preoperative Calorie Restriction on Renal Function After Cardiac Surgery
The aim of this study is to assess the effect of a diet prior to cardiac surgery on the common postoperative decline of renal function. Until now, there is no known drug or procedure to preserve the kidneys from this impairment.
- Trial name
- CR_KCH (NCT01534364)
- Testing
- calorie restriction
- Where
- Germany
- Volunteers
- 82 people
- Sponsor
- University of Cologne