Clinical trials: Functional Magnetic Resonance Imaging (fMRI)
Brain Tumor
Evaluation of Preoperative Functional Magnetic Resonance Imaging (fMRI) in Patients With Brain Tumors
The purpose of this study is to test the accuracy of using an imaging technique called breath-holding functional magnetic resonance imaging (BH fMRI) in addition to the standard imaging test described above.
- Trial name
- NCT03604302
- Testing
- fMRI Paradigms
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Pleasure
RS-fMRI to Nutrient Shakes
Resting state functional magnetic resonance imaging (rsfMRl) of the brain is used to measure pleasantness after consumption of four different milkshakes with added sugars or sweeteners.
- Trial name
- NCT02745730
- Testing
- Glucose, Fructose, Sucralose
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
PostTraumatic Stress Disorder
PTSD Among Victims of Sexual Abuse and Changes in Structural and Functional Brain Connectivity
The goal of this study is to identify the early modifications in fronto-temporal connectivity in female victims who developed PTSD, compared to female victims who did not develop the disorder, and to healthy control females.
- Trial name
- COPTSD (NCT01405495)
- Testing
- MRI-based techniques (sMRI, fMRI, DTI, ASL)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Fibromyalgia, Chronic Pain
Tai Chi Intervention and Brain Imaging Study Among Fibromyalgia Patients and Healthy Controls
This exploratory study proposal is the first pilot brain imaging study to determine if Tai Chi can modulate brain resting state functional connectivity (rsFC) and brain morphometry among fibromyalgia (FM) patients and healthy…
- Trial name
- fMRI/FMEX (NCT02407665)
- Testing
- Tai Chi
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
Healthy
Task Augmentation of Transcranial Magnetic Stimulation (TMS)
This pilot, within-subjects, randomized proof-of-concept study investigates the effects of activating the DLPFC promotion system on TMS treatment outcomes.
- Trial name
- TaskTMS (NCT04586205)
- Testing
- active TMS, IASP Task, SST Task
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Healthy Volunteers
Investigating the Analgesic Potential of (2R,6R)-HNK in Acute Pain in Healthy Volunteers
Background: Opioid drugs are often prescribed for acute and chronic pain. But these drugs are addictive, and they lead to more than 14,000 overdose deaths in the United States each year.
- Trial name
- NCT07504601
- Testing
- (2R,6R)-Hydroxynorketamine
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Obesity
Effect of Intranasal Insulin on Cognitive Processes and Appetite
This study investigates the effect of intranasal insulin on cognitive processes (behavioural and neural) in healthy lean and obese female adults.
- Trial name
- NCT03632681
- Testing
- Intranasal Insulin
- Where
- United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Cerebral Metastases Patients
Neurococognitive and Functioal Assessment of Patients With Brain Metastases
The investigators seek to perform an observational study in patients with brain metastases that are to undergo whole brain radiation therapy (WBRT) or stereotactic radiosurgery (SRS) treatment in order to quantify any baseline…
- Trial name
- NCT01861405
- Testing
- neuropsychological testing and quality of life assessments, Standard of Care WBRT or SRS, Functional magnetic resonance imaging
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Painful Diabetic Neuropathy
Functional Magnetic Resonance Imaging of Brain Activity in Patients With Painful Diabetic Neuropathy
Patients with painful diabetic neuropathy (PDN) often combine with anxiety and depression. However, the pathogenesis of PDN is unclear, especially the mechanism associated with central nervous system.
- Trial name
- NCT03700502
- Testing
- resting-state functional Magnetic Resonance Imaging
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Cognitive Impairment, Functional Magnetic Resonance Imaging
Functional Magnetic Resonance Imaging (fMRI) of Brain in ICU Survivors With Cognitive Impairment
Long-term cognitive dysfunction greatly influences patient's quality of life after critical illness. However,its neurophysiological basis remains unknown.This is a 3 year fMRI study conducted at the Jiangyin people's Hospital.
- Conditions
- Cognitive Impairment, Functional Magnetic Resonance Imaging, Septic Shock, Inflammation
- Trial name
- NCT03946839
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jian-jun Yang
Healthy
Studying the Hedonic and Homeostatic Regulation of Food Intake Using Functional MRI
The purpose of this study is to investigate how gut hormones and brain areas respond differently to gastric distention, tasteless calories, or palatable food and how this alters appetite.
- Trial name
- NCT05525845
- Testing
- Functional Magnetic Resonance Imaging (pCASL-MRI), Intragastric Balloon, Elemental Meal
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Amnesia
Transient Global Amnesia (TGA). Exploratory Study of the Default Mode Network During the Acute Phase
The transient global amnesia, in which the memory disorder is massive, transient and pure, offers a unique model for exploring episodic memory.
- Trial name
- ICTUS (NCT02010853)
- Testing
- IRMf
- Where
- France
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Orthotopic Neobladder
The Supraspinal Control of Lower Urinary Tract Function in Patients With Orthotopic Sigmoid Neobladder.
Orthotopic sigmoid neobladder surgery is one of the ideal urinary diversion methods after radical cystectomy.In recent years, functional imaging studies have revealed brain regions related to urinary system function, but brain…
- Trial name
- NCT05558111
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Healthy, Healthy Adult
Effects of Repetitive Transcranial Magnetic Stimulation on Two Cerebellar Targets
The purpose of this study is to understand how different areas of the cerebellum (a part of the brain) control different functions and how they can be influenced by non-invasive brain stimulation.
- Trial name
- StimCervelet (NCT07561229)
- Testing
- Active rTMS - Lobule VIII, Active rTMS - Crus I/II, Cognitive and Motor Assessment Battery
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Repetitive Negative Thinking, Neurofeedback
Effect of Mindfulness-based Neurofeedback for Adolescents With Elevated Repetitive Negative Thinking
This study will test the hypotheses that adolescent with repetitive negative thinking who at at-risk for serious mental illness will show greater default mode network (DMN) connectivity than healthy controls, at-risk adolescents…
- Trial name
- CHARMS (NCT07055217)
- Testing
- Mindfulness Training, Mindfulness-based Neurofeedback (Real mbNF)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Healthy
Comparison of Externally and Self-Initiated Movements
This study will use magnetic resonance imaging (MRI) to investigate how the brain controls voluntary movements triggered by an external stimulus or self-initiated. Registered HCMS healthy normal volunteers may participate.
- Trial name
- NCT00028197
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Healthy Volunteer
A Study To Assess Effects Of PF-04958242 On Bold Functional Magnetic Resonance Imaging During Working Memory Activation And Arterial Spin Labeling At Rest In Healthy Subjects
The primary objective of this study aims to determine whether the drug affects brain activity in healthy volunteers, either when the participants are performing a memory task, or when lying at rest.
- Trial name
- NCT01365338
- Testing
- PF-04958242
- Where
- 2 sites in United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Biogen
Healthy
Infant Diet Effects on Brain Function and Language Processing (fMRI)
The purpose of this study is to identify neurocognitive functions and language processing of 8-year-old children who were fed either breast milk, milk-based formula or soy-based formula during the first year of life.
- Trial name
- NCT00735423
- Testing
- No intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Cognition, Affect (Mental Function)
ETASCAN Project: ETAS Project 2
This study aims to investigate the chronic effects of ETAS® on cognitive, affective and neural outcomes in healthy adults aged 60-80 years with mild to moderate subjective cognitive complaints.
- Conditions
- Cognition, Affect (Mental Function), Sleep, MRI
- Trial name
- ETASCAN (NCT07550140)
- Testing
- ETAS®
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Reading
Exposure
Neutral Correlates of Risk-taking in Adolescents Exposed to Drugs Prenatally
Objective- To use fMRI to compare brain activity at rest and during memory and decision making tasks in normal children and in children exposed in utero to drugs of abuse.
- Trial name
- NCT01365988
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
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