Clinical trials: Functional Motor Disorder
Spastic Diplegic Cerebral Palsy, Hemiplegic Cerebral Palsy
Strength Training in Children With Spastic Diplegic and Hemiplegic Cerebral Palsy Receiving Botulinum Toxin
To estimate the effectiveness of strength training after administration of botulinum toxin in children with spastic diplegic cerebral palsy and hemiplegic cerebral palsy on muscle volume and gross motor function.
- Trial name
- NCT04177186
- Testing
- Strength training, Strength training with botulinum toxin
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Asir John Samuel
Parkinson Disease, Balance
Non-motor Symptoms, Balance, Muscle Strength, and Functional Mobility in Patients With Parkinson's Disease
The purposes of this study is to examine balance, muscle strength, and mobility in relation with non-motor symptoms (NMSs) in patients with Parkinsosn's Disease (PD).
- Conditions
- Parkinson Disease, Balance, Muscle Strength, Mobility
- Trial name
- NCT04420910
- Testing
- Non-Motor Symptoms, Balance, Lower Limb Strength
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Type 2 Diabetes, Impaired Glucose Tolerance
Exercise Effects on Cardiovascular Risk Factors, Quality of Life, Muscle Function in Type 2 Diabetes and Healthy Persons
A sedentary lifestyle is known to be a risk factor to developing type 2 diabetes. The aim of this study was to determine the effects of adding regular Nordic walking to daily physical activity.
- Trial name
- SMIDIG (NCT00852982)
- Testing
- Exercise
- Where
- Sweden
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Low Back Pain, Low Back Pain, Recurrent
Structural White and Gray Matter Correlates of Impaired Muscle Control and Deficient Pain Processing
Although the cause of persistent non-specific low back pain (LBP) remains unknown, structural and functional alterations of the brain, alterations in the lumbar muscles and dysfunction of the central nervous system have been…
- Conditions
- Low Back Pain, Low Back Pain, Recurrent, Low Back Pain, Chronic, Healthy Volunteers
- Trial name
- B~Maps (NCT06143319)
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Ghent
Peripheral Arterial Disease, Critical Limb Ischemia
Exercise Rehabilitation for Patients With Critical Limb Ischemia After Revascularization
Peripheral arterial disease (PAD) affects more than 200 million people worldwide. This disease occurs with narrowing and occlusion of arteries supplying oxygenated blood to the organs and limbs.
- Trial name
- NCT03839953
- Testing
- Supervised Exercise Program, Best Medical Therapy
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Osteoarthritis
Study of Effectiveness of Hand Exercises to Treat Symptoms of Hand Osteoarthritis
Participants in this study will do hand exercises once per day for 16 weeks. The purpose of the study is to determine if hand exercises designed to improve range of movement and strength are an effective way to decrease…
- Trial name
- NCT00375947
- Testing
- Hand Exercise
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- The Arthritis Research Institute of America
Spastic Diplegic Cerebral Palsy
Repetitive Transcranial Magnetic Stimulation Versus Botulinum Injection on Spasticity on Children With Diplegic Cerebral Palsy
This trial will enroll 75 children with spastic diplegic cerebral palsy both matched in age, sex, degree of disability and cognitive functions with the same exclusion criteria undergoing the same physical therapy.
- Trial name
- NCT06218316
- Testing
- botulinum toxin A, Transcranial Magnetic Stimulation, Rehabilitation Training Protocol
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- MTI University
Physical Function, Cognitive Decline
Face-to-face vs Online Physical Exercise in Seniors Living in Nursing Homes (ExerMOT-NH)
The benefits of multicomponent physical exercise (MPE) in the mental and physical health of older adults are widely accepted. However, during Covid19 pandemic, some face-to-face programs for physical exercise were canceled.
- Conditions
- Physical Function, Cognitive Decline, Psychological Well-Being
- Trial name
- ExerMOT-NH (NCT06352749)
- Testing
- Advice to increase physical activity and reduce sedentary behavior, Online Physical Exercise, Face-to-Face Exercise
- Where
- 4 sites in Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)
Healthy
Use of Real-Time Functional Magnetic Resonance Imaging Neurofeedback to Improve Motor Function in Cerebellar Ataxia
This project will study the feasibility of motor rehabilitation in people with cerebellar ataxia using real-time functional magnetic resonance imaging neurofeedback (rt-fMRI NF) in conjunction with motor imagery.
- Trial name
- fMRI (NCT05436249)
- Testing
- Neurofeedback treatment, At-home therapy
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Ulcerative Colitis, Inflammatory Bowel Diseases
Effects of Exercise in Patients With Ulcerative Colitis
The aim of this study is to investigate the effects of moderate to high intensity exercise on gut function and inflammatory markers in patients with Ulcerative Colitis (UC), and to compare them with individuals of matched age who…
- Trial name
- NCT04143490
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Manchester Metropolitan University
Stroke
Effects of Aerobic Exercise on the Cerebral Arterial System, Cognitive, and Motor Function in Post-stroke Patients.
Background: Stroke is the second leading cause of death and disability worldwide and in Hong Kong, 6.2% of all registered deaths in 2020 were due to cerebrovascular disease.
- Trial name
- NCT05706168
- Testing
- treadmill exercise, Cycle ergometer exercise
- Where
- Hong Kong
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Obesity, Vascular Dysfunction
DNA Methylation and Vascular Function
The main objective is to examine DNA hypomethylation as an underlying mechanism for the increased production of inflammatory cytokines and the impaired vascular function in obese individuals and as a potential target for…
- Trial name
- NCT03527420
- Testing
- Exercise training
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Calorie Deficiency, Fasting
Effects of Calorie Restriction and Cold Stimuli on Health-related Indicators, Cognitive and Motor Functions
The goal of this clinical trial was to identify if duration of acute calorie restriction (CR)/fasting or combination CR with cold stimuli have any effects on mental and physical health-related markers, and to clarify if different…
- Conditions
- Calorie Deficiency, Fasting, Cold Exposure
- Trial name
- NCT05545943
- Testing
- 2-days of zero calorie restriction and whole-body cold-water immersion, 6-days of calorie restriction, 2-days of zero calorie restriction without whole-body cold-water immersion
- Where
- Lithuania
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Spinal Cord Injuries (SCI), Spinal Cord Injury
Transcutaneous Spinal Electrical Stimulation to Improve Exercise Function After Spinal Cord Injury.
Our overall objective is to decrease the prevalence of multiple sedentary-related diseases that are secondary consequences of spinal cord injury (SCI).
- Conditions
- Spinal Cord Injuries (SCI), Spinal Cord Injury, Spinal Injury
- Trial name
- NCT07692191
- Testing
- Transcutaneous spinal electrical stimulation (TSES)
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Clinical Deterioration
Prevention of Functional and Cognitive Impairment Through a Multicomponent Exercise Program in Hospitalized Older Adults
The goal of this clinical trial is to determine whether a multicomponent exercise program improves functional capacity and cognitive status in hospitalized elderly patients aged 75 and older.
- Trial name
- PREDISC (NCT06634147)
- Testing
- Exercise
- Where
- 2 sites in Spain
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Fundacion Miguel Servet
Parkinsons Disease (PD)
Neuroimaging of Parkinson's
Parkinson's Disease (PD) is a neurodegenerative disorder caused by dysfunction in both subcortical structures and the cortex. The investigators recently discovered a new brain system called the Somato-Cognitive Action Network…
- Trial name
- NCT07024875
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Obesity
Acute Cognition and Exercise
The central hypothesis is that, while both groups will benefit from the exercise session, participants with obesity will exhibit greater gains in cognitive control, relative to healthy weight adults.
- Trial name
- ACE (NCT05078203)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Diabetes Type 2
Exercise Study on Cardiac Function in Patients With Diabetes Mellitus Type 2 and Diastolic Dysfunction
The aim of the study is to compare the effects of aerobic interval training and the IDF recommendations on physical activity on cardiac function and CV risk factors in patients with diabetes.
- Trial name
- NCT01206725
- Testing
- Exercise
- Where
- Norway
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Healthy
Influence of Fast and Slow Imagined Muscle Contractions on Muscle Function or Central Nervous System Properties
The goal of this randomized clinical trial is to learn if imagining fast or slow muscle contractions causes different responses for nervous system excitability and muscle function in young, healthy males and females in.
- Trial name
- NCT06627491
- Testing
- Imagined muscle contractions
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Kennesaw State University
Spinal Muscular Atrophy
Aerobic Training in Patients With Spinal Muscular Atrophy Type III
Spinal muscular atrophy type III, (SMAIII) is a disease in the nerve cells in the spinal cord which leads to to progressive muscle weakness and atrophy. No effective treatment is available for SMA.
- Trial name
- NCT02003937
- Testing
- Aerobic conditioning
- Where
- Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet