Clinical trials: Functional Neurological Disorder
Parkinson Disease, Healthy
Neurofeedback Training for PD
The goal of this clinical trial is to test neurofeedback training in both people with Parkinson's disease and healthy control. The main questions it aims to answer are: To demonstrate that EEG based or STN LFP based neurofeedback…
- Trial name
- NCT05987865
- Testing
- Neurofeedback training
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Stroke
Recovery Prediction of Motor Function Using Neuroimaging Techniques in Subacute Stroke Patients
Prediction of recovery from stroke can assist in the planning of impairment-focused rehabilitation. To achieve better prediction for clinical purposes, this study investigated a new prediction model with low inter-individual…
- Trial name
- NCT03365596
- Testing
- Conventional therapy
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Knee Osteoarthritis
Effects of Concurrent Exercise Combinations in Knee Osteoarthritis:
This study will include 3 different groups of intervention. First group of knee osteoarthritis patients will be applied both strengthening and 30 minutes bicycle exercises in the same session, 2 days strecthing exercises and 30…
- Trial name
- NCT05054686
- Testing
- Stretching and Aerobic Exercise at Clinic, Strenghthening and Aerobic Exercise, Strengthening, Stretching and Aerobic Exercises at clinic
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Frailty, Sarcopenia
Effect of Exercise-education Program PERMANENTO in Late Life
The general aim of the present study is to create and empirically evaluate (RCT trial) an online education and exercise program (called PERMANENTO) to help older adults to understand the wider consequences of being active and…
- Trial name
- PERMANENTO (NCT06133894)
- Testing
- Exercise program PERMANENTO inspired by developmental kinesiology
- Where
- Czechia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
TBI (Traumatic Brain Injury), Brain Concussion
Dual-Task Exercise for Mild Traumatic Brain Injury (mTBI)
The investigators previously developed a virtual 14-day dual-task walking exercise program and tested its feasibility with individuals with mild traumatic brain injury (mTBI) history.
- Conditions
- TBI (Traumatic Brain Injury), Brain Concussion, Clinical Trial, Rehabilitation
- Trial name
- NCT06037603
- Testing
- Brain & Walk Exercise Every Day (BraW-Day)
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Muscle Loss, Obesity
Long-term Intervention Effects of a Personalized, Home-based Exercise Program and Nutritional Advice, Along With the Inclusion of a Pre-workout Multi-ingredient Supplement on the Body Composition, Functional Capacity and Quality of Life of Middle-aged and Older Adults (40-70 Years)
The purpose of this study is to analyse the potential benefits of ingesting a commercially available pre-workout multi-ingredient supplement providing ~90 Kcal.
- Conditions
- Muscle Loss, Obesity, Obesity, Abdominal, Weight Loss
- Trial name
- NCT04630977
- Testing
- Multi-ingredient Pre-workout supplement, Progressive Resistance Training, Nutritional Patterns Guideline
- Where
- United Kingdom
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Greenwich
Voice Disorders
Brain Mapping of Voice Control
Some voice disorders are caused by uncontrolled muscle actions that affect the larynx or voice box. The purpose of this study is to understand 1) how the brain controls voice production; 2) how changes in sensation within the…
- Trial name
- NCT00066911
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Hypoxic-Ischemic Encephalopathy, Neonatal Encephalopathy
Healthy Little Eyes
The purpose of this research study is to gather more information on how eye injury is related to a baby's future development and see if eye function and brain test results can be used, along with current measures, to better…
- Conditions
- Hypoxic-Ischemic Encephalopathy, Neonatal Encephalopathy, Encephalopathy
- Trial name
- NCT05971446
- Testing
- Visual Evoked Potential (VEP), Electroretinogram (ERG)
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Metabolism - Cerebral Energy
The Efficient Brain Study
Cerebral energy metabolism declines with advanced aging, and is implicated in age-related cognitive decline, Alzheimer's disease (AD), and other forms of neurodegenerative disease (Parkinson's disease).
- Trial name
- NCT02771366
- Testing
- Fermented Papaya Preparation, Granulated Sugar
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Florida
Multiple Sclerosis, Cognition Disorders
Linking Cognitive Functioning to Multimodal Imaging in Multiple Sclerosis (MS)
Multiple sclerosis (MS) is the most common progressive neurologic disorder to occur in adults of working-age. Despite longstanding recognition of cognitive impairment as a symptom of MS, two obstacles in measurement have limited…
- Trial name
- NCT03723356
- Testing
- Siemens Biograph mMR (molecular MR), fMRI, Diffusion Spectrum Imaging (DSI)
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Upper Extremity Paresis
PNF Strengthening and De-lorme and Watkins Exercises on Upper Extremity Function and Strength in Stroke Patients
The aim of this study is to evaluate the effects of proprioceptive neuromuscular facilitation strengthening exercises and de-Lorme and Watkins exercises program in stroke patients with upper limb weakness in chronic stroke…
- Trial name
- NCT05904795
- Testing
- PNF strengthening exercises, de-lorme and watkins exercises
- Where
- Pakistan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Anesthesia, Anesthesia, Local
A Study in Healthy Male Volunteers to Investigate the Safety and Tolerability of a Single Dose of Neosaxitoxin Alone and in Combination With Bupivacaine (With and Without Epinephrine) for Brachial Plexus Blockade
Neosaxitoxin is a new compound that is in clinical development as local anesthetic for surgical anesthesia and postoperative analgesia.
- Conditions
- Anesthesia, Anesthesia, Local, Analgesia
- Trial name
- NCT03399435
- Testing
- Neosaxitoxin combined with bupivacaine low and epinephrine (T1), Bupivacaine low combined with epinephrine (C1), Bupivacaine high combined with epinephrine (C2)
- Where
- Netherlands
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Grünenthal GmbH
Chronic Plantar Fasciitis, Control Group
Frequency of Neuropathic Pain in Patients With Plantar Fasciitis
Study Design This prospective cross-sectional study was undertaken between November 2023 and March 2024. Written and verbal informed consent was obtained from all patients.
- Trial name
- NCT06348017
- Where
- Turkey (Türkiye)
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Yozgat City Hospital
Granulomatosis With Polyangiitis
Neutrophils as Prognostic Factors in Granulomatosis With Polyangiitis (Formerly Named Wegener's Granulomatosis)
Anti-neutrophil cytoplasm antibodies (ANCA)-associated vasculitis are rare diseases characterized by inflammation of blood vessels.
- Trial name
- NeutroVasc (NCT01862068)
- Testing
- Blood samples and clinical data, Blood sample
- Where
- France
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Spinal Cord Diseases
Reorganization of Brain Functions in Patients With Cervical Myelopathy Using fMRI and MRS
Decompressive surgery to relieve symptoms of spinal cord compression due to dysfunction, such as arthritis, has proved variable in success.
- Trial name
- NCT00447343
- Testing
- Decompressive cervical spine surgery, fMRI and MRS scan
- Where
- Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Obstructive Sleep Apnoea, Obesity
Peripheral Vascular Function in Obstructive Sleep Apnoea
Peripheral vascular function is impaired in people with obstructive sleep apnoea who are untreated compared with age-, weight- and sex-matched healthy controls.
- Trial name
- NCT01619748
- Where
- 2 sites in United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Dementia Alzheimers, Dementia With Lewy Bodies
Dementias and Microbiota Composition: Is Possible to Revert the Dementia Symptoms Reverting the Microbiota Composition?
Dementia is the major cause of disability and dependency among older adults worldwide affecting memory, cognitive abilities and behavior, interfering with one's ability to perform daily lives activities.
- Conditions
- Dementia Alzheimers, Dementia With Lewy Bodies, Parkinson Disease Dementia, Dementia Frontotemporal
- Trial name
- DEM-BIOTA (NCT05943925)
- Testing
- No intervention, Probiotic supplement
- Where
- Spain
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Iodine Deficiency, Thyroid
Iodine Impact on Thyroid Function and Psychomotor Development, Observational Study in the Portuguese Minho Region
Full intellectual capabilities are achieved only if crucial nutrients are present during development. Iodine deficiency is the most common cause of preventable brain harm in infants.
- Conditions
- Iodine Deficiency, Thyroid, Pregnancy Related, Psychomotor Impairment
- Trial name
- IodineMinho (NCT04288531)
- Testing
- Iodine supplementation
- Where
- 10 sites in Portugal
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- University of Minho
Prader-Willi Syndrome, Obesity
Plasma Adiponectin Level and Vascular Endothelial and Smooth Muscle Cell Function in Children With Prader-Willi Syndrome
Context: Prader-Willi syndrome (PWS) is a genetic disorder characterized by childhood-onset obesity and endocrine dysfunction that leads to cardiovascular disability and early death within the first 3 decades of life.
- Trial name
- NCT01479322
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Diabetes Mellitus, Neuropathy, Diabetic
Assessments and Interventions for Hand Neuropathy in DM
This study is to investigate the effects of task-based biofeedback training compared with home-based programs on sensorimotor function and quality of life for diabetic patients with neuropathic hands.
- Trial name
- NCT03847129
- Testing
- Biofeedback training, Home-based tendon gliding and resistance training
- Where
- Taiwan
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
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