Clinical trials: Functional Neurological Disorder
Osteoarthritis, Pain
An Investigation Into the Role of Walking in Treating the Symptoms of Knee Osteoarthritis: The WalkOut Study
There are over 8.75 million people in the United Kingdom with osteoarthritis in their knees. The effect of this condition can be debilitating. Symptoms are due to wear and tear of the knee joint.
- Conditions
- Osteoarthritis, Pain, Arthritis, Gonarthritis
- Trial name
- WalkOut (NCT02748291)
- Testing
- Walking, Department of Health Physical Activity Guidelines
- Where
- United Kingdom
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Bruxism, Sleep
Investigation of Respiratory Function in Bruxism
The aim of the study was to evaluate the respiratory functions, sleep quality and headache severity of individuals with bruxism and to compare them with the control group without bruxism.
- Trial name
- NCT07133035
- Testing
- Pulmonary function test, Fonseca Anamnestic Index, Jenkins Sleep Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Atılım University
Muscle Weakness, Myalgia
Coenzyme Q10 in Older Athletes Treated With Statin Medications
The purpose of this study is to evaluate the effect of coenzyme Q10 administration in improving mitochondrial function as measured by anaerobic threshold in older athletes on a stable dose of statin medication.
- Conditions
- Muscle Weakness, Myalgia, Side Effects of Statins
- Trial name
- NCT01026311
- Testing
- Coenzyme q 10
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Richard Deichmann, MD
Mild Cognitive Impairment, Alzheimer Disease
Skeletal Muscle as a Mediator of Exercise Induced Effects on Metabolism & Cognitive Function: Role for Myokines & miRNAs
The purpose of this study is to determine specific changes in muscle secretory profile (myokines, miRNA) in association with neurodegenerative disease progression and metabolic dysfunction.
- Conditions
- Mild Cognitive Impairment, Alzheimer Disease, Parkinson Disease, Healthy Volunteers
- Trial name
- Brain-Muscle (NCT02253732)
- Testing
- 3 months exercise intervention program
- Where
- 2 sites in Slovakia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Slovak Academy of Sciences
TBI (Traumatic Brain Injury)
Clinical Significance of circMETTL9 Gene in Traumatic Brain Injury
Objective: The relevance of circMETTL9 to the degree of injury, disturbance of consciousness, cognitive function and prognosis in patients with moderate to severe traumatic brain injury (TBI) remains unknown.
- Trial name
- NCT05484921
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital of Nantong University
Multiple Sclerosis
The Effect of Dietary Salt Intake on Immune Function in Patients With Multiple Sclerosis
The purpose of this work is to investigate the influence of dietary salt intake on immune function in multiple sclerosis (MS) subjects and healthy controls.
- Trial name
- NCT02282878
- Testing
- High/Low Sodium Diet
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Yale University
Cerebral Small Vessel Diseases
Recovery Improved in Covert Stroke With Exercise
Silent ischemic, also known as "covert stroke vascular disease" (CSVD), contributes to neurological deficits that are caused by damage to small blood vessels in the brain.
- Trial name
- RISE-2 (NCT02068391)
- Testing
- Stretching Program, Exercise Program
- Where
- Canada
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Obstructive Sleep Apnea, Sleep Apnea
Validity and Reliability of the 6-Minute Pegboard and Ring Test (6PBRT) in Adults With Obstructive Sleep Apnea Syndrome
Obstructive sleep apnea (OSA) is a common sleep-related breathing disorder characterized by recurrent upper airway obstruction during sleep, leading to intermittent hypoxia and sleep fragmentation.
- Trial name
- NCT07465874
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mardin Artuklu University
Oral Frailty, Depression
Group Reading and Oral Exercise Program for Older Adults
Depression is common among older adults and is often associated with declines in physical and oral health. Non-pharmacological, community-based interventions are needed to support both mental and physical well-being.
- Conditions
- Oral Frailty, Depression, Sarcopenia, Physical Function Decline
- Trial name
- NCT07550335
- Testing
- Reading and Oral Exercise Program
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
Multiple Sclerosis
The Minnesota Manual Dexterity Test As A Measure Of Hand Function in Multiple Sclerosis
The aim of the study is to report the results of manual dexterity using the Minnesota Manual Dexterity Test in people with Multiple Sclerosis.
- Trial name
- NCT04721340
- Testing
- Test Group, Control Grup
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Shoulder Pain
Correlation Between Cyriax's Functional Examination and Ultrasound Examination in Patients With Shoulder Pain
Shoulder problems cause substantial disability in daily living, work, leisure activity, and exercise. The presence of shoulder problem such as rotator cuff pathology reported was highly predictive of impaired health-related…
- Trial name
- NCT02688205
- Testing
- Cyriax's functional examination, Ultrasound examination
- Where
- Taiwan
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Frailty, Physical Disability
Vitamin D and Calcium Supplementation at Danish Nursing Homes
Nursing home residents are in high risk of vitamin D deficiency, which negatively affects bone health. Vitamin D and calcium supplements have shown to increase bone density and reduce fracture risk and may affect daily physical…
- Conditions
- Frailty, Physical Disability, Aging, Muscle Weakness
- Trial name
- NCT04956705
- Testing
- Vitamin D and calcium
- Where
- 2 sites in Denmark
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- University College Copenhagen
Knee Osteoarthritis, Limitation, Mobility
The Effect of Graded Motor Imagery on Pain and Function in Individuals With Knee Osteoarthritis
The aim of this study is to investigate whether Graded Motor Imagery (GMI) application is as effective as Transcutaneous Electrical Nerve Stimulation (TENS) in individuals with knee osteoarthritis (OA).
- Trial name
- NCT05925517
- Testing
- Graded Motor Imagery (GMI), Transcutaneous Electrical Nerve Stimulation (TENS), Conventional Physiotherapy Program
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Artvin Coruh University
TBI (Traumatic Brain Injury)
Long Lasting Effect of Hyperbaric Oxygen Therapy on Cognitive Function in Traumatic Brain Injury Patients
To evaluate the cognitive functions of patients who suffered brain injury due to traumatic head injury and were previously treated in a hyperbaric chamber between one and four years after the end of treatment.
- Trial name
- NCT07430150
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Hydrocephalus, Alzheimer Disease
MR Evaluation of Cerebrospinal Fluid (CSF) Dynamics
The Researchers are trying to test a MR imaging method for detection of Cerebral Spinal Fluid (CSF) flow in the brain to help diagnosis and better understand diseases that affect brain function.
- Trial name
- NCT04099823
- Testing
- MRI screening form, Urine pregnancy test, MR brain
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Age-related Macular Degeneration, Dementia
Words on the Brain: Can Reading Rehabilitation for Age-Related Vision Impairment Improve Cognitive Functioning?
Age-related vision impairment and dementia both become more prevalent with increasing age. Research into the mechanisms of these conditions has proposed that some of their causes (e.g., macular degeneration/glaucoma and…
- Conditions
- Age-related Macular Degeneration, Dementia, Low Vision, Low Vision Aids
- Trial name
- WOTB (NCT04276610)
- Testing
- Low Vision Reading Rehabilitation
- Where
- 2 sites in Canada
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
Bereavement, Depressive Disorder
Consequences of Conjugal Bereavement in Adults
Bereavement refers to the expected reactions and sadness associated with the loss of a loved one. It has been reported that the loss of a spouse is rated as the major life stressor among survivors of varying ages and diverse…
- Conditions
- Bereavement, Depressive Disorder, Immunologic Disease, Mental Disorder
- Trial name
- NCT00001659
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Obstructive Sleep Apnea, Malocclusion
Changes in Upper Airway Anatomy, Quality of Life Measures, and Polysomnographic Parameters Using A Functional Dental Appliance
A prospective study measuring changes in upper airway anatomy, quality of life measures, and polysomnographic parameters using a functional dental appliance (Homeoblock)
- Trial name
- NCT02805764
- Testing
- Homeoblock
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Insomnia
Study of an Evening Dose of Eszopiclone on Next Day Driving Ability & Psychomotor/Memory Function in Healthy Volunteers
Male and female healthy volunteers. Patients must also possess a full current driving license (for at least one year), and be a regular car driver.
- Trial name
- NCT00368160
- Testing
- Eszopiclone
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sumitomo Pharma America, Inc.
Rehabilitation of Upper Limb Motor Function in Hemiplegia Due to Supratentorial Cerebral Infarction Using Armeo Power Robot
Effects of Armeo Power Robot Therapy on Upper Limb Recovery in Hemiplegic Stroke Patients
This study investigates the effectiveness of combining Armeo Power robotic therapy with conventional rehabilitation techniques to improve upper limb motor function in patients with hemiplegia caused by supratentorial cerebral…
- Trial name
- BV108/RAPPHCN (NCT06708065)
- Testing
- Armeo Power robot restores upper limb motor function., A Home Exercise Program, Occupational therapy activities
- Where
- Vietnam
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Hanoi Medical University
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