Clinical trials: Functional Neurological Symptom Disorder, open to volunteers
Oral Health
A Study on the Correlation Between Oral Health and Delirium in Surgical Inpatients
Delirium is a clinical syndrome characterized by acute attention deficits, altered consciousness, and fluctuating cognitive dysfunction, typically triggered by multifactorial causes such as physical illness, medication use, or…
- Trial name
- NCT06969092
- Testing
- Oral Frailty
- Where
- China
- Volunteers
- 550 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Multiple Sclerosis, Gait Disorders, Neurologic
"Balance, Gait, and Motion Analysis in Multiple Sclerosis"
The goal of this observational cross-sectional study is to investigate the relationship between functional measures of balance and gait and objective kinetic and kinematic parameters in people with Multiple Sclerosis (MS).
- Conditions
- Multiple Sclerosis, Gait Disorders, Neurologic, Postural Balance, Motion Analysis
- Trial name
- MS-BALGAIT (NCT07630311)
- Where
- 2 sites in Greece
- Volunteers
- 40 people
- Sponsor
- University of Patras
Sarcopenia
Creatine HCl Supplementation in Sarcopenia: A Randomized Controlled Study
The CONCRET-SARCOPA trial is a 12-week, double-blind, randomized controlled study designed to evaluate the efficacy of creatine HCl supplementation in older adults with sarcopenia.
- Trial name
- SARCOPA (NCT07285226)
- Testing
- Experimental 1, Experimental 2
- Where
- Serbia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Center for Health Sciences, Serbia
Stroke, Hemiparesis
Personalized Robotic Telerehabilitation for Upper Limb Functional Recovery After Stroke in a Home-Based Setting
Stroke is a leading cause of long-term disability worldwide, with upper-limb impairment representing a major determinant of functional limitation and reduced independence.
- Conditions
- Stroke, Hemiparesis, Upper Extremity Paresis, Motor Impairment
- Trial name
- ROBOHOME (NCT07590349)
- Testing
- Robotic-Assisted Telerehabilitation Virtual Reality-Based Telerehabilitation, Virtual reality-based rehabilitation platform without robotic assistance
- Volunteers
- 70 people
- Sponsor
- University of Campania Luigi Vanvitelli
Cerebral Palsy, Hemiplegic
Effects of Robotic Hand Therapy on Hand Function and Dexterity in Cerebral Palsy
This randomized controlled trial aims to evaluate the effects of robotic hand therapy using the Syrebo E12 soft-robotic glove compared with conventional physiotherapy on hand function and manual dexterity in children with…
- Trial name
- NCT07571668
- Testing
- Robotic Hand Therapy, Conventional physical Therapy
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Riphah International University
Lung Transplantation
Impact of Inspiratory Muscle Training (IMT) With Intermittent Variable Resistance (IVR) Versus Constant Resistance (CR) on Functional Capacity in Lung Transplantation (LTx) Patients (I-TRAIN-LTx Study)
Objectives: Primary Objective: To compare Maximum Inspiratory Pressure (MIP) in lung transplant (LT) patients between the use of inspiratory muscle training (IMT) with intermittent variable resistance (IVR) or constant resistance…
- Trial name
- I-TRAIN-LTx (NCT06963190)
- Testing
- Constant Resistance (CR), Intermittent Variable Resistance (IVR)
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Hospital Universitario Marqués de Valdecilla
Migraine in Children, Complex Regional Pain Syndromes
Supraspinal Processing of Sensory Aspects of Pain
The goal of this basic science study is to learn about the brain mechanisms of chronic pain across different chronic pain syndromes in pediatric patients.
- Conditions
- Migraine in Children, Complex Regional Pain Syndromes, Musculoskeletal Pain, Functional Abdominal Pain Syndrome
- Trial name
- SCP (NCT05814497)
- Testing
- Multisensory Task, Graphesthesia, Divided attention
- Where
- United States
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Knee Osteoarthristis
BFR Training and Knee Osteoarthritis
Knee osteoarthritis (KOA) is a chronic, progressive degenerative joint disease characterized by cartilage and bone degeneration, synovial inflammation, and structural changes.
- Trial name
- NCT07590323
- Testing
- Standard Treatment, Pain neuroscience education, Blood flow restriction training
- Where
- Saudi Arabia
- Volunteers
- 90 people
- Sponsor
- University of Hail
Hallux Valgus
Foot Orthoses in the Treatment of Painful Hallux Valgus
This randomized pilot feasibility trial will evaluate the feasibility of conducting a full-scale randomized controlled trial comparing custom-made, prefabricated, and sham foot orthoses in people with painful hallux valgus.
- Trial name
- NCT07781735
- Testing
- Podiatric Education, Exercise, Prefabricated foot orthoses
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- Université du Québec à Trois-Rivières
Chronic Pain
Pain Management Teams Using Whole Health to Optimize Function and Safety in Veterans: The TEAMWORK Trial
The focus of this study is to determine whether adding Whole Health Coaching (WHC) improves pain care among adults with chronic pain and who are currently working with a pain management team (PMT) at the VA.
- Trial name
- TEAMWORK (NCT07149870)
- Testing
- Pain Management Team + Whole Health Coach (PMT-WHC), Pain Management Team-Usual Care (PMT-UC)
- Where
- 5 sites in United States
- Volunteers
- 432 people
- Sponsor
- VA Office of Research and Development
Critical Illness, Delirium
A Multi-Modal Combination Intervention to Promote Cognitive Function in Older Intensive Care Unit Survivors
Up to 25% of intensive care unit (ICU) survivors experience cognitive impairment comparable in severity to mild Alzheimer's disease and related dementias after hospital discharge.
- Conditions
- Critical Illness, Delirium, Cognitive Impairment, Cognitive Decline
- Trial name
- SLEEP-COG (NCT06411561)
- Testing
- SLEEP + COG, COG, SLEEP
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Washington
Consciousness Disorders
Measuring Brain Complexity to Detect and Predict Recovery of Consciousness in the ICU
Disorders of consciousness (DoC) caused by severe brain injury affect millions of people worldwide each year. A patient's level of consciousness in the intensive care unit (ICU) significantly impacts the recovery from disability…
- Trial name
- COMPASS (NCT06568536)
- Testing
- Repeated behavioral assessments, functional electroencephalography and brain imagery, TMS-EEG
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- Massachusetts General Hospital
Parkinson Disease
Deep Brain Stimulation in Parkinson's Disease: Motor and Functional Outcomes
Introduction: Parkinson's Disease (PD) is a progressive neurodegenerative condition characterized by classic motor symptoms, such as bradykinesia, rigidity, resting tremor, and postural instability, which directly compromise the…
- Trial name
- NCT07567599
- Testing
- Deep Brain Stimulation
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Federal University of Minas Gerais
Aphasia, Acquired, Chronic Stroke
VR and Scrip Training of PWA, Randomized Controlled Trial
The goal of this RCT is to investigate if computerized script training may promote functional communication and nonverbal cognitive functions of Cantonese-speaking PWA, and whether VR may further magnify the treatment outcomes.
- Trial name
- VRSTPWA (NCT06722092)
- Testing
- VR-based script training, Conventional script training
- Volunteers
- 105 people
- Sponsor
- The Hong Kong Polytechnic University
Stroke Sequelae, Gait Disorders, Neurologic
Efficacy of Trans-spinal Magnetic Stimulation on Functional Mobility in Chronic Stroke Patients
The goal of this clinical trial is to learn if trans-spinal magnetic stimulation works to treat gait disorders in chronic stroke adults. It will also learn about the safety of trans-spinal magnetic stimulation.
- Conditions
- Stroke Sequelae, Gait Disorders, Neurologic, Stroke
- Trial name
- NCT06593184
- Testing
- Trans-spinal magnetic stimulation
- Where
- 3 sites in Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Federal de Pernambuco
Myofascial Pain Syndrome (MPS)
High-Intensity Laser Therapy for Trapezius Myofascial Pain (HILT-TRAP Study)
This study aims to evaluate the effectiveness of optimized High-Intensity Laser Therapy (HILT) compared with sham treatment in patients with trapezius myofascial pain syndrome.
- Trial name
- HILT-TRAP Stud (NCT07352787)
- Testing
- High-Intensity Laser Therapy
- Where
- Iraq
- Volunteers
- 104 people
- Sponsor
- Neveen Abd El Maksoad Kohaf
Plantar Fasciopathy, Chronic Pain
One Cause of Heel Pain is Plantar Fasciopathy (PF). In Most Cases, a Heel Spur is Frequently Present Alongside PF. We Aim to Evaluate the Efficacy of Corticosteroid Injection and Radiofrequency Ablation, Along With Tissue Elasticity Assessed by Ultrasound, in Patients With Chronic Pain (≥6 Months).
Heel pain is common among adults. One cause of heel pain is plantar fasciopathy (PF). In most cases, a heel spur, a bony prominence that extends into the plantar fascia, is frequently present alongside PF.
- Conditions
- Plantar Fasciopathy, Chronic Pain, Corticosteroid Injection, Radiofrequency Ablation
- Trial name
- NCT07120204
- Testing
- Corticosteroid Injection, Radiofrequency thermocoagulation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- TC Erciyes University
Severe Permanent Uni or Bilateral Non-pulsatile Tinnitus, Without Associated Vestibular Pathology
Evaluation of Deep Brain Stimulation (DBS) of the Right Operculum 3 (OP3) in Permanent Non-pulsatile Disabling Tinnitus (TINNOP3-DBS)
This pilot study aims at evaluating the effectiveness of the treatment of unilateral or bilateral, non-pulsatile, disabling, tinnitus, without vestibular dysfunction, using Deep Brain Stimulation (DBS) of the parieto-insular…
- Conditions
- Severe Permanent Uni or Bilateral Non-pulsatile Tinnitus, Without Associated Vestibular Pathology, Resistant to Therapeutic Failure, With or Without Hearing Loss
- Trial name
- TINNOP3-DBS (NCT04296097)
- Testing
- DBS
- Where
- France
- Volunteers
- 7 people
- Sponsor
- University Hospital, Grenoble
Fibromyalgia (FM), Chronic Migraine Headache
Relieving Chronic Pain: Psychosomatic Mechanisms and Psychological Interventions in Fibromyalgia and Chronic Headache
Pain is one of the most important manifestations of the disease state and significantly affects people\'s quality of life. According to the International Association for the Study of Pain (IASP), pain is not only a sensory…
- Trial name
- FIBROMIG (NCT06652724)
- Testing
- Dynamic interpersonal therapy (DIT), technique of expressive writing (TSE), Treatment as Usual (TAU)
- Where
- 2 sites in Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Low Muscle Strength, Malnutrition
Efficacy of Oral Nutritional Supplement in Community-Dwelling Adults Following Acute Care
The study aims to determine the effects of Oral Nutritional Supplement (ONS) added to usual care on body weight compared with usual care alone in community-dwelling adults aged 55 years and older who are at risk of malnutrition…
- Trial name
- NCT07753239
- Testing
- ONS, Standard of Care (SOC)
- Where
- 7 sites in Thailand
- Volunteers
- 304 people
- Sponsor
- Abbott Nutrition