Clinical trials: Functional Outcomes
Mild Cognitive Impairment (MCI), Sarcopenia
Project Gnosis: the Neurophysical and Psychosocial Health Outcomes of Tai Chi for Older Adults with Cognitive Concerns or Mild Cognitive Impairment
Mild Cognitive Impairment (MCI) in older adults is linked to muscle loss (sarcopenia) and can lead to dementia, with pain further impacting cognitive and physical performance.
- Trial name
- NCT06828926
- Testing
- Tai Chi
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ohio University
Comparative Effectiveness Research
Comparative Functional Vision Outcomes: DAILIES TOTAL1 Toric vs. Spherical Lenses in Asian Astigmatic Patients
The goal of this comparative clinical trial is to assess the effectiveness of DAILIES TOTAL1 Toric Contact Lenses compared to Spherical Equivalent Contact Lenses in improving the functional vision of astigmatic patients, with a…
- Trial name
- NCT06230263
- Testing
- Visual acuity test
- Where
- Hong Kong
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Mopsy Research
Hernia, Ventral
Transverse Abdominal Plane Anesthesia for Abdominal Wall Reconstruction
The aim of this study is to evaluate the short-term postoperative outcomes in the abdominal wall reconstruction population using an intraoperative local anesthetic infusion.
- Trial name
- NCT02274077
- Testing
- EXPAREL, Normal Saline
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Chester Mays
Cognitive Function
Radicle Clarity CNM™: A Study Assessing the Impact of Health and Wellness Products on Cognitive Function and Related Health Outcomes Among E-Gamers
Radicle Clarity CNM™: A randomized, double-blind, placebo-controlled direct-to-consumer study assessing the impact of health and wellness products on cognitive function and related health outcomes among E-Gamers.
- Trial name
- NCT07386964
- Testing
- Clarity Active Product
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Critical Illness
Functional Outcomes in Children Post Critical Illness
Improvements in medical care have led to decreasing mortality rates in critically ill children, which have been reported to be as low as 5%.
- Trial name
- NCT03730844
- Where
- Singapore
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
PRF, Hypospadias
A Multicenter Randomized Controlled Trial Comparing Platelet-Rich Fibrin and Ventral Dartos Flap as Intermediate Layers in Tabularized Incised Plate (TIP) Urethroplasty for Distal Hypospadias With Mild Penile Curvature
Distal hypospadias is the most common form of hypospadias. The Tubularized Incised Plate (TIP) repair is the standard surgical technique for this condition; however, complications such as fistula formation and meatal stenosis…
- Conditions
- PRF, Hypospadias, Distal Hypospadias, Hypospadias Repair
- Trial name
- PRF (NCT07045545)
- Testing
- - Group A: Platelet-rich fibrin membrane prepared intraoperatively and applied over neourethra, Group B: Ventral dartos flap rotated over neourethra
- Where
- Uzbekistan
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- National Children's Medical Center, Uzbekistan
Osteoarthritis of the Knee, Degenerative Osteoarthritis
Platelet-Rich Plasma and the Effects of NSAIDs on Pain and Functional Scores in Knee Osteoarthritis
The primary research purpose is to determine if the use of a drug therapy intervention (each study participant will be randomly assigned to receive one of 3 study medications which will be blinded from everyone, including the…
- Conditions
- Osteoarthritis of the Knee, Degenerative Osteoarthritis, Knee Pain Chronic
- Trial name
- PRPNSAIDsKOA (NCT05742763)
- Testing
- Ibuprofen and PRP, Acetaminophen and PRP
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- QC Kinetix LLC
Oxidative Stress, Inflammation
Effects of Magnesium and Spinning Training on Echocardiographic, Inflammatory, and Aerobic Outcomes
Regular aerobic exercise may improve cardiorespiratory fitness while modulating systemic inflammation and oxidative stress. Spinning, as a structured indoor cycling modality, provides a practical aerobic exercise model with…
- Conditions
- Oxidative Stress, Inflammation, Physical Fitness, Echocardiography
- Trial name
- NCT07662954
- Testing
- Spinning Training, Magnesium Supplementation
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Karamanoğlu Mehmetbey University
Distal Radius Fracture
Impact of Early ADL Participation on Outcomes Post DRF
This study is a randomized controlled trial (RCT). This RCT which will study the effect of performing daily activities early after a distal radius fracture being treated conservatively in a cast. This study will have two groups.
- Trial name
- NCT05650996
- Testing
- ADL/Cast Care instruction, Cast Care Instruction
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- George Washington University
Cognitive Function
Radicle Clarity 24: A Study of Health and Wellness Products on Cognitive Function and Related Health Outcomes
A randomized, double-blind, placebo-controlled direct-to-consumer study of health and wellness products on cognitive function and related health outcomes
- Trial name
- NCT06294431
- Testing
- Clarity Active Study Product 1.1 Usage, Clarity Active Study Product 2.1 Usage
- Where
- United States
- Volunteers
- 4,794 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Coronary Artery Disease, Coronary Heart Disease
Impact of Cardiac Rehabilitation on Patient Outcomes
Objective: This study aimed to retrospectively evaluate the impact of cardiac rehabilitation (CR) on functional capacity, depressive symptoms, health-related quality of life, and sleep quality in patients with heart disease.
- Trial name
- NCT07468955
- Testing
- Exercise Based Cardiac Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Premature Birth, Obstructive Lung Disease
Pulmonary Outcomes of Bronchopulmonary Dysplasia in Young Adulthood
Preterm birth alters the normal sequence of lung development with lasting respiratory consequences. It is still unclear whether observed respiratory morbidities in preterm born individuals reflect sequelae from a non-progressive…
- Conditions
- Premature Birth, Obstructive Lung Disease, Bronchopulmonary Dysplasia
- Trial name
- NCT02820818
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Anterior Cruciate Ligament Rupture
BFRT in Adolescents After ACL Reconstruction
This is an interventional study that will examine effects of blood flow restriction training (BFRT) in adolescents aged 12-18 after anterior cruciate ligament reconstruction surgery (ACLR).
- Trial name
- NCT04390035
- Testing
- Blood Flow Restriction using Delfi Personalized Tourniquet System
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Healthcare of Atlanta
Aging, Cognitive Decline
Impact of a Novel Brain Longevity Supplement Containing the Postbiotic Urolithin A (Mitopure) on Cognitive Function and Related Health Outcomes
This is a parallel group, randomized, double-blind, placebo-controlled clinical study assessing the safety and effects of a novel nutritional product on self-reported cognitive function and health in adults that reside in the…
- Conditions
- Aging, Cognitive Decline, Brain Fog, Cognitive Function
- Trial name
- CLARITY (NCT07060898)
- Testing
- Active Product
- Where
- United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Concussion, Mild, Concussion, Severe
Ketone Supplementation in Adolescents Post-Concussion
Adolescent brains undergo rapid and significant changes in structural architecture and functional organization during development.
- Conditions
- Concussion, Mild, Concussion, Severe, Concussion, Brain, Concussive Injury
- Trial name
- NCT04079907
- Testing
- Ketone
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Mental Health, Loneliness
The Impact of a Telephone Reminiscence Program
The purpose of this study is to better understand how a telephone reminiscence program impacts reminiscence functions and mental health outcomes in community-dwelling older adults.This study will take 12 weeks to complete and…
- Conditions
- Mental Health, Loneliness, Social Isolation
- Trial name
- NCT05977608
- Testing
- Telephone Reminiscence Intervention
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Athletic Injuries
Functional and Performance Effects of a 4-week Weightlifting Program in Highly Trained Adolescent Basketball Athletes
Weightlifting is an increasingly used intervention in the sport field to improve both function and performance outcomes. However, the effects in a pediatric and adolescent population are not well described, and require further…
- Trial name
- NCT05824780
- Testing
- Exercise training
- Where
- Spain
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Degenerative Joint Disease, Osteoarthritis
Comparison of Clinical Outcomes and Performance of Total Knee Replacement Patients Before and After Surgery
This study is to determine the relevancy of clinical scales for outcome measures as compared to flexion angle and other gait measures.
- Conditions
- Degenerative Joint Disease, Osteoarthritis, Knee Injury, Trauma, Connective Tissue Disorder
- Trial name
- TKR (NCT01379118)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Respiratory Function, Pediatric Anesthesia
Effects of Different Inspiratory:Expiratory Ratios on Respiratory and Recovery Outcomes During Dental Procedures Under General Anesthesia in Pediatric Patients
This observational study aims to evaluate the effects of different inspiratory to expiratory (I:E) ratios (1:2 vs. 1:3) during mechanical ventilation in pediatric patients undergoing dental procedures under general anesthesia.
- Conditions
- Respiratory Function, Pediatric Anesthesia, General Anesthesia
- Trial name
- NCT07323420
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Parkinson's Disease
Trial Comparing Functional Outcomes of Awake vs. Asleep Deep Brain Stimulation (DBS) for Parkinson's Disease
The purpose of the proposed study is to demonstrate that the functional outcomes of DBS surgery utilizing the "asleep" technique are not inferior to those reported for traditional "awake" DBS technique.
- Trial name
- NCT02401308
- Testing
- Deep Brain Stimulation surgery
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix