Clinical trials: Functional Outcomes
Vitreomacular Traction, Vitreomacular Adhesion
Assessment of Patients Treated With JETREA® for Vitreomacular Traction
The purpose of this study is to observe the anatomical and functional outcomes of ocriplasmin (JETREA®) over a 6-month follow-up period.
- Trial name
- NCT02035748
- Testing
- Ocriplasmin
- Volunteers
- 628 people
- Sponsor
- Alcon Research
Weight Loss, Obesity
Health Outcomes After Participating in Exercise (HOPE)
Aging is associated with significant declines in muscle mass, strength, and physical performance, all of which lead to disability, loss of independence, and adverse clinical outcomes.
- Conditions
- Weight Loss, Obesity, Aging
- Trial name
- HOPE (NCT03430115)
- Where
- United States
- Volunteers
- 588 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Skin Appearance, Skin Texture
Clinical Evaluation of a Multi-functional Beauty Device on Cosmetic Skin Outcomes
This study is designed to evaluate changes in cosmetic skin appearance and safety following at-home use of a multi-functional beauty device over a 4-week treatment period among approximately 50 participants.
- Conditions
- Skin Appearance, Skin Texture, Skin Sagging, Wrinkles
- Trial name
- NCT07871708
- Testing
- Multi-functional Home-use Beauty Device, Topical Skincare Serum, Skincare Mask
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- APR Co., Ltd.
Renal Cell Carcinoma
Oncological and Functional Outcomes of Laparoscopic Partial Nephrectomy in Renal Cell Carcinoma Stages T1 Versus T2a: Prospective Comparative Study.
RCC represents around 3% of all cancers, with the highest incidence occurring in Western countries . Within the several RCC risk factors identified, smoking, obesity, and hypertension are most strongly associated with RCC .
- Trial name
- NCT05486871
- Testing
- laparoscopic partial nephrectomy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Trauma, Congenital Bone and Joint Abnormalities
Telemedicine Consultation in Trauma and Orthopedic
The purpose of this study is to determine whether telemedicine consultations (lead by standard scheme)allows to increase quality of anatomical and functional outcomes and improve clinical work-flow at patients with acute bone and…
- Conditions
- Trauma, Congenital Bone and Joint Abnormalities, Joint Diseases, Orthopedic Surgery Complications
- Trial name
- TeleTO (NCT00815243)
- Testing
- Telemedicine consultation, Treatment plan
- Where
- 5 sites in Ukraine
- Volunteers
- 300 people
- Sponsor
- Donetsk National Medical University
Obesity
Effects of Exercise Intensity in Obese Children and Adolescents
The prevalence of paediatric obesity has increased over the last two decades and with it, an increased diagnosis of lifestyle-related diseases in children and adolescents.
- Trial name
- NCT01991106
- Testing
- High intensity interval training, Moderate intensity continuous training, Nutritional advice
- Where
- 2 sites in Australia, Norway
- Volunteers
- 100 people
- Sponsor
- Norwegian University of Science and Technology
Fragility Fractures of the Pelvis (FFP), Osteoporotic Fractures
Functional Outcomes in Older Adults With Fragility Fractures of the Pelvis: The FFP-France Study
Fragility fractures of the pelvis (FFP) are an increasingly common complication of osteoporosis in older adults and are associated with substantial morbidity, loss of independence, and mortality.
- Trial name
- NCT07871084
- Testing
- Observational Assessment of Fragility Fractures of the Pelvis
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Total Hip Arthroplasty (THA), Kinesiophobia (Fear of Movement)
Effect of Cognitive Behavioral Therapy on Kinesiophobia and Functional Outcomes After Total Hip Arthroplasty.
The goal of this clinical trial study is to evaluate the effectiveness of cognitive behavioral therapy in reducing kinesiophobia and improving Clinical outcomes in postoperative patients following total hip arthroplasty The main…
- Trial name
- NCT07427758
- Testing
- Cognitive-behavioral therapy, Exercise
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Total Knee Anthroplasty, Total Knee Arthroplasty Recovery
The Effects of Mir Shakeel Teleintegrated Therapy Plan in Patients Undergoing Total Knee Arthroplasty
This randomized controlled trial aims to evaluate the effectiveness of a newly developed Modified Structured Telerehabilitation Intervention Protocol (MSTITP) compared with conventional in-person physical therapy in patients…
- Trial name
- RCT (NCT07239258)
- Testing
- Mir Shakeel Teleintegrated Therapy plan, Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 150 people
- Sponsor
- Lincoln University College Malaysia
Boswellia Serrata, Irritable Bowel Syndrome
Positive Outcomes of the Supplementation With Lecithin-based Delivery Form of Curcuma Longa and of Boswellia Serrata in IBS
Small bowel dysbiosis (SBD), is a frequent finding in subjects with irritable bowel syndrome (IBS). The formula-tion in sunflower lecithin (Phytosome) of Curcuma longa and Boswellia serrata demonstrated beneficial effects on…
- Trial name
- NCT06407609
- Testing
- Curcuma and boswellia extracts plus low fodmap diet, Low Foodmap diet
- Where
- Italy
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Azienda di Servizi alla Persona di Pavia
Herniated Disc, Sciatica Due to Intervertebral Disc Disorder
Effects of Neural Mobilization Combined With Manual Therapy on Infrared Thermography, Inflammatory Markers and Clinical Outcomes in Patients With Lumbar Disc Herniation: A Randomized Controlled Clinical Trial
The objective of this randomized controlled clinical trial is to evaluate whether manual therapy combined with neural mobilization can improve pain, functional impairment, quality of life, inflammatory markers, and infrared…
- Trial name
- NCT07752199
- Testing
- Neural Mobilization, Manual Therapy
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Longhua Hospital
Constipation - Functional
Adherence/Outcomes After Use of Constipation Action Plan
Adherence to recommendations for treatment of chronic constipation in pediatric population is often poor. This study is attempting to improve adherence, and outcomes, by implementing a trial of a constipation action plan plus…
- Trial name
- NCT03821532
- Testing
- Constipation Action Plan
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Temporomandibular Joint Ankylosis
Comparison of Three Osteotomy Techniques in Temporomandibular Joint Ankylosis Surgery
Temporomandibular joint (TMJ) ankylosis is a condition in which the jaw joint becomes partially or completely fused, resulting in restricted mouth opening and difficulties with chewing, speaking, and daily activities.
- Trial name
- TMJ-OST (NCT07883889)
- Testing
- Piezoelectric Surgical Device, Ultrasonic Bone Scalpel, Conventional Reciprocating Saw
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Ankara University
Anterior Cruciate Ligament Rupture, Tendon Injuries
Shear-Wave Elastography of Regenerated Hamstring Tendons After ACL Reconstruction (SWE-ACL)
Anterior cruciate ligament (ACL) reconstruction using autologous hamstring tendon grafts is a commonly performed procedure. Although the semitendinosus and gracilis tendons demonstrate regeneration at the donor site, the…
- Conditions
- Anterior Cruciate Ligament Rupture, Tendon Injuries, Muscle Weakness
- Trial name
- SWE-ACL (NCT07555782)
- Testing
- Shear-Wave Elastography Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Edema Leg
Pneumatic Compression Versus Anti-thromboembolic Exercises for Patients Undergoing Total Hip Arthroplasty
This study is a randomized controlled trial, with two parallel arms. The open-label study will be conducted in accordance with the helsinky statement and good clinical practice standards.
- Trial name
- NCT05312060
- Testing
- PC Pneumatic compression, AE Antithromboembolic exercises
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- Luca Marin
Hematologic Diseases, Acute Myeloid Leukemia
Muscle Dysfunction in Patients With Haematological Diseases
PURPOSE: To evaluate the prevalence and prognostic value of sarcopenia in patients diagnosed with hematological cancer diseases.
- Conditions
- Hematologic Diseases, Acute Myeloid Leukemia, Acute Lymphoid Leukemia, Myelodysplastic Syndromes
- Trial name
- NCT05150561
- Where
- Denmark
- Volunteers
- 216 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Crohn Disease (CD), Dynamic Prediction Model
Development of a Dynamic Prediction Model for Crohn's Disease-Related Intestinal Surgery Using Longitudinal Indices of Routine Blood Tests: A Single-Center Retrospective Cohort Study
This single-center retrospective cohort study aims to develop and internally validate a dynamic prediction model that uses longitudinal data from routinely collected blood tests to continuously assess the risk of Crohn's disease…
- Trial name
- NCT07644390
- Volunteers
- 500 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Coronary Artery Bypass Graft Surgery Patients
Improving Outcomes and Quality of Life After CABG
The principal objective to this randomized trial is to compare the efficacy of two strategies of intra-operative hemodynamic management during cardiopulmonary bypass among patients undergoing primary elective coronary artery…
- Trial name
- NCT00256620
- Testing
- Mean arterial pressure during cardiopulmonary bypass 80 mmHg vs. customized
- Where
- United States
- Volunteers
- 412 people
- Sponsor
- Weill Medical College of Cornell University
Trauma
Investigating Outcomes of Lower Limb Trauma
This is an observational study, which aims to firstly develop a sensor-based objective mobility assessment. This will then be used to profile and compare the outcomes of patients who undergo amputation with those who have limb…
- Trial name
- NCT01691950
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Imperial College London
TBI (Traumatic Brain Injury)
Impact Of Early Cognitive Rehabilitation On Functional Outcomes Following Moderate Traumatic Brain Injury
Purpose of the study: This study aims to detect the impact of early cognitive rehabilitation on functional outcomes with patients following moderate traumatic brain injury.
- Trial name
- NCT06981897
- Testing
- early cognitive therapy program in addition to selected physical therapy program (positioning, chest care exercise)., selected physical therapy program (Chest care exercise, passive movement of the four limbs) in addition to early cognitive therapy program, Control group
- Where
- 3 sites in Egypt
- Volunteers
- 34 people
- Sponsor
- Amany Saadallah Hassan Mobarez
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