Clinical trials: Functional Outcomes
Social Anxiety Disorder
Neural Markers of Treatment Mechanisms and Prediction of Treatment Outcomes in Social Anxiety
The purpose of this clinical trial is to answer the question: can the investigators predict which adults with social anxiety disorder (SAD) will successfully respond to treatment? To answer this question, the investigators plan…
- Trial name
- NCT05683223
- Testing
- Group CBT for Social Anxiety Disorder, Sertraline, Individual CBT for Social Anxiety Disorder
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Osteoarthritis, Pain
Efficacy of Exercise on Quality of Life and Physical Function in Patients With Knee Osteoarthritis
The overall contribution of this study is to increase the knowledge of the efficacy of strength and aerobic exercise on knee related quality of life, knee pain, and physical function in patients with knee osteoarthritis (OA).
- Trial name
- NCT01682980
- Testing
- Strength training, Aerobic exercise
- Where
- Norway
- Volunteers
- 207 people
- Sponsor
- Oslo University Hospital
Acute Ischemic Stroke
Effect of Human Urinary Kallidinogenase on Inflammatory Factors in Acute Ischemic Stroke (KIF-AIS)
The goal of this clinical trial is to explore the changes in the expression levels of inflammatory factors before and after the early treatment of Human Urinary Kallidinogen (HUK) in the acute ischemic stroke.
- Trial name
- NCT06696703
- Testing
- Human urinary kininogenase(HUK)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Acute Ischemic Stroke, Large Vessel Occlusion
Inflammatory Markers and Prognosis After Cerebral Thrombectomy in Large Vessel Occlusion
The goal of this observational study is to describe the local change in interleukin-6 (IL-6) across a blood clot in adults with acute ischemic stroke caused by anterior circulation large vessel occlusion who are undergoing…
- Trial name
- IMPACT-LVO (NCT07754942)
- Testing
- Prospective Mechanical Thrombectomy Cohort
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Zhongshan Hospital Xiamen University
Trauma, Critical Illness
Optimizing Recovery in Trauma Patients by Integrating Enhanced Nutrition Delivery
This is a prospective, randomized, controlled trial designed to evaluate the impact of enhanced protein supplementation compared to a standard of care nutrition delivery in critically ill older adult trauma patients.
- Trial name
- NCT06521086
- Testing
- Nutrition Supplements - Fresubin KCAL Drinks
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Duke University
Piriformis Syndrome
Effects of Hold Relax With Agonist Contraction and Active Release Therapy on Clinical Outcomes in Piriformis Syndrome
The aim of this study is to compare the effects of hold relax agonist contraction and active release therapy on reducing pain intensity, improving functioning and sleep quality in patient with piriformis syndrome.
- Trial name
- NCT05370378
- Testing
- Hold Relax with Agonist Contraction, Active Release Therapy
- Where
- Pakistan
- Volunteers
- 82 people
- Sponsor
- University of Lahore
Hip Fractures, Rehabilitation
Use of Mobile App to Enhance Geriatric Hip Fracture Rehabilitation
The steady increase in the incidence of geriatric hip fracture places an increasing burden on health care service in Hong Kong. Post fracture limitations are prominent and restrain many of the elderly from returning to community…
- Trial name
- NCT04053348
- Testing
- Home-based rehabilitation program using mobile app
- Where
- Hong Kong
- Volunteers
- 144 people
- Sponsor
- Hospital Authority, Hong Kong
Flexor Tendon Injury, Tendon Injury - Hand
Effects of Different Wrist Positions in Dorsal Blocking Orthoses After Flexor Tendon Repair
This randomized controlled study aims to compare the effects of three different wrist positions (30° extension, neutral, and 30° flexion) used in dorsal blocking orthoses during early active mobilization after zone I-II flexor…
- Trial name
- NCT07489235
- Testing
- 3D-Printed Dorsal Blocking Orthosis (wrist 30 degree extension), 3D-Printed Dorsal Blocking Orthosis (wrist neutral), 3D-Printed Dorsal Blocking Orthosis (wrist 30 degree flexion)
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Sedanur Güngör
Functional Dyspepsia
Treatment Outcomes For Functional Dyspepsia Based On Current International Guidelines In Multi-Ethnic Asian Patients
Functional dyspepsia (FD) is among the most established and common functional gastrointestinal disorders (FGIDs). FD is subdivided into two subtypes based on symptoms: epigastric pain syndrome (EPS) and postprandial distress…
- Trial name
- NCT04918017
- Testing
- Treatment based on subtypes: Esomeprazole or Itopride, Treatment with proton pump inhibitor regardless of subtype: Esomeprazole
- Where
- Malaysia
- Volunteers
- 180 people
- Sponsor
- University of Malaya
Amputation of Knee, Back Pain
Biofeedback Retention in Individuals With AKA
More than two million Americans are currently living with a full or partial limb loss, and an additional 185,000 amputations occur each year. The majority of amputations occur in the lower limbs.
- Conditions
- Amputation of Knee, Back Pain, Osteo Arthritis Knee
- Trial name
- NCT05126485
- Testing
- Haptic Biofeedback from SageMotion Biofeedback System
- Where
- 2 sites in United States
- Volunteers
- 35 people
- Sponsor
- San Jose State University
Anterior Cruciate Ligament Injuries, Arthroscopy
Functional Outcomes Comparison in Patients Using Knee Brace Post ACL Reconstruction With Autograft Bone Quadricep Tendon
This study is a study looking for the relationship between variables with a prospective cohort design to determine functional outcomes subjectively and objectively in patients with and without braces after ACL reconstruction with…
- Conditions
- Anterior Cruciate Ligament Injuries, Arthroscopy, Braces
- Trial name
- ACL (NCT05457452)
- Testing
- Knee Brace
- Where
- Indonesia
- Volunteers
- 32 people
- Sponsor
- Universitas Indonesia
Geriatric Hip Fracture
Geriatric Hip Fractures Caregiver Programme
Objective: To study whether fracture hip patients can be benefited from the empowerment program Hypothesis to be tested Primary hypothesis: empowerment program can improve the patient's functional recovery.
- Trial name
- NCT05393349
- Testing
- Empowering the patient and caregiver for early and safe discharge of patients with geriatric hip fractures
- Where
- Hong Kong
- Volunteers
- 125 people
- Sponsor
- The University of Hong Kong
Kidney Transplant, DCD Kidney
NRP + ex Situ HMPO2 vs NRP Alone in DCD Kidney Transplantation
The goal of this clinical trial is to learn if the combination of Normothermic Regional Perfusion (NRP) at the time of organ procurement with ex situ Hypothermic Oxygenated Perfusion (HMPO2) of kidneys recovered from donors after…
- Trial name
- OxyPerf (NCT07779187)
- Testing
- Ex situ hypothermic oxygenated machine preservation
- Where
- 3 sites in Sweden
- Volunteers
- 214 people
- Sponsor
- Karolinska University Hospital
Tumor, Stroke
Different Intraoperative Blood Pressure Management on Postoperative Cognitive Function in Tumor Patients（PRECISION）
This is a randomized controlled study to explore whether perioperative blood pressure management with different strategies can reduce the incidence of delirium and postoperative cognitive impairment and serious perfusion related…
- Trial name
- PRECISION (NCT06711432)
- Testing
- Norepinephrine or phenylephrine
- Where
- China
- Volunteers
- 214 people
- Sponsor
- Zhejiang Cancer Hospital
Myofascial Pain Syndrome (MPS), Neck Pain
Dual Frequency Low-Level Laser Therapy in Myofascial Trigger Points of Upper Trapezius
The goal of this clinical trial is to determine whether dual frequency low-level laser therapy can reduce pain, improve function, and increase neck movement in patients with myofascial trigger points in the upper trapezius…
- Conditions
- Myofascial Pain Syndrome (MPS), Neck Pain, Myofacial Trigger Points
- Trial name
- DF-LLLT-MTP-UT (NCT07137728)
- Testing
- Red Low-Level Laser Therapy, Infrared Low-Level Laser Therapy, Dual Frequency Low-Level Laser Therapy
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- University of Lahore
Gynecologic Cancer, Frailty
Cognitive and Physical Frailty as Predictors of Decision Satisfaction in Geriatric Gynecologic Oncology
This prospective observational study aims to evaluate the association between preoperative cognitive function, measured by the Montreal Cognitive Assessment (MoCA), and physical frailty, assessed using the Clinical Frailty Scale…
- Conditions
- Gynecologic Cancer, Frailty, Cognitive Impairment, Geriatric Oncology
- Trial name
- GYNCOGFRAIL (NCT07085000)
- Testing
- No Intervention - Observational Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Izmir City Hospital
Ischemic Stroke, Acute, Treatment Outcome
Effect of Early Versus Late Initiation of Edaravone Dexborneol on Neural Function in Patients With Acute Ischemic Stroke
The primary objective of this study was to evaluate the efficacy and safety of initiation of edaravone dextivel therapy compared with placebo in patients with acute ischaemic stroke (early and late) and to explore the optimal…
- Trial name
- EARLYS (NCT05885919)
- Testing
- Edaravone Dexborneol Concentrated Solution for injection
- Where
- 3 sites in China
- Volunteers
- 212 people
- Sponsor
- Xiangya Hospital of Central South University
Healthy, Vitamin D Deficiency
Can Correction of Low Vitamin D Status in Infancy Program for a Leaner Body Composition?
One in four infants are born with low amounts of vitamin D stored in their body. This study is designed to test whether improving vitamin D status quickly after birth helps infants to build muscle and to normalize growth.
- Conditions
- Healthy, Vitamin D Deficiency, Gestational Diabetes
- Trial name
- NCT02563015
- Testing
- cholecalciferol, Reference 400
- Where
- Canada
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- McGill University
Functional Constipation
Core-Based Movement and Nutritional Counselling for Stress and Metabolic Outcomes in Overweight Women With Functional Constipation
This study will investigate the effect of core-based movement and nutritional counselling on stress, serum cortisol, and lipid profile in overweight women with functional constipation.
- Trial name
- NCT07694830
- Testing
- Guideline-Based Nutritional Counselling, Core-Based Movement Exercise Program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Ankle Sprains
Smartphone App to Improve Functional Outcomes in Ankle Sprains
Ankle sprains are the most common musculoskeletal complaint of children presenting to the emergency department (ED). Healing can often be protracted, leading to prolonged pain, missed school and work, and delayed return to a…
- Trial name
- SPRAIN (NCT03564015)
- Testing
- Smartphone app, Paper handout
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
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