Clinical trials: Functional Outcomes
Parkinson Disease
Speech and Voice Outcomes Following HD-tDCS Over the Left SMA
Pharmaceutical and neurosurgical treatments reliably ameliorate the cardinal motor symptoms in PD but, they often yield inconsistent outcomes for speech and voice disorders, with some studies showing exacerbation of pre-treatment…
- Trial name
- NCT06245070
- Testing
- Active transcranial direct current stimulation
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Louisiana State University and A&M College
Shoulder Arthropathy
Quality of Life, Functional Outcomes and Costs in Shoulder Arthroplasty
This prospective observational study aims to collect and analyse data on functional outcomes, quality of life indicators, and costs in patients undergoing primary total shoulder arthroplasty (shoulder replacement) surgery.
- Trial name
- NCT05940974
- Testing
- Questionnaire administration
- Where
- Russia
- Volunteers
- 12 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Dementia, Pain
Dissemination and Implementation of Function Focused Care for Assisted Living
This study will evaluate pain, management of pain, behavioral symptoms, and the quality of staff-resident interactions between residents with and without dementia, test the relationship of these variables to participation in…
- Trial name
- NCT03459118
- Testing
- Function Focused Care
- Where
- 2 sites in United States
- Volunteers
- 853 people
- Sponsor
- University of Maryland, Baltimore
Ulcerative Colitis
Outcomes of Transanal Tran-section and Single-stapled (TTSS) Ileal Pouch-Anal Anastomosis
This study aims to compare the functional and surgical outcomes of Ulcerative Colitis (UC) patients undergoing Transanal Transection and Singl-Stapled (TTSS) versus Double-stapled Ileal Pouch-Anal Anastomosis (IPAA)
- Trial name
- TTSS-Pouch (NCT06331637)
- Testing
- Transanal Transection and Single-Stapled anastomosis (TTSS), Double-stapled anastomosis
- Where
- Italy
- Volunteers
- 174 people
- Sponsor
- Istituto Clinico Humanitas
Malunion of Fracture of Radius
Evaluating the Utility of Bone Grafts in Open Wedge Corrective Osteotomy and Plate Fixation
INTRODUCTION A variety of bone grafts and substitutes are available for filling bone defects in the distal radius after corrective osteotomy, but the harvesting of bone from the iliac crest is the gold standard as it allows easy…
- Trial name
- WOPPeR (NCT06093763)
- Testing
- Group without bone grafting, Group with bone grafting
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Maastricht University Medical Center
Older Adults (65 Years and Older), Cognition
Effects of Breathing Exercises on Cognition in Older Adults
The goal of this interventional clinical trial is to investigate the effects of breathing exercises added to balance training on cognitive function in individuals aged 65 years and older.
- Conditions
- Older Adults (65 Years and Older), Cognition, Balance Control in Elderly, Fall Prevention in Healthy Aging
- Trial name
- NCT07505914
- Testing
- Balance Training Program, Inspiratory Muscle Training, Breathing Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Pseudarthrosis, Clavicle Fracture
Descriptive Single-center Retrospective Study of a Series of Cases of Clavicle Pseudarthrosis: Epidemiology, Surgical Management, and Functional Outcomes
1. Study identification Study title: PSEUDO-CLAV - Single-center retrospective descriptive study of clavicle nonunion (pseudarthrosis): epidemiology, surgical management, and functional outcomes PSEUDO-clav_Notice non oppositi……
- Conditions
- Pseudarthrosis, Clavicle Fracture, Clavicle Fracture, Non Union/Malunion
- Trial name
- PSEUDO-CLAV (NCT07414654)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Brest
Stroke
Research Proposal of New Technologies and Standardization of Physiotherapy Stroke Rehabilitation
One of the main goals of physiotherapy in stroke rehabilitation is to maximize walking ability of patients as soon as possible. Traditionally, intervention selection and application of neuroplasticity to stroke patients depends…
- Trial name
- NCT05420103
- Testing
- Accelerated Stroke Ambulation Program
- Where
- Hong Kong
- Volunteers
- 650 people
- Sponsor
- Tai Po Hospital
Clinical Outcomes, Functional Outcomes
Prospective G7 Dual Mobility Total Hip PMCF
This is a prospective multi-center clinical evaluation following recipients of the G7 Dual Mobility hip device. The primary objective is to characterize survivorship of the G7 hip at five years post-index procedure.
- Conditions
- Clinical Outcomes, Functional Outcomes, Radiological Outcomes, Survivorship
- Trial name
- NCT03308929
- Testing
- G7 Dual Mobility hip
- Where
- 6 sites in United States
- Volunteers
- 250 people
- Sponsor
- Zimmer Biomet
Motor Function
Effects of Home-based CIMT and Clinic-based CIM on Stroke
Constraint induced movement therapy (CIMT) is based on the theoretical basis that constraining the unaffected limb following injury of the brain such as stroke can help overcome learned non-use.
- Trial name
- NCT06465251
- Testing
- Home-based CIMT, Clinic-based CIMT, Control
- Where
- Hong Kong
- Volunteers
- 96 people
- Sponsor
- The Hong Kong Polytechnic University
Osteoarthritis, Knee, TKA
Comparing Efficacy Between Restricted Kinematic Alignment vs Mechanical Alignment in Bilateral TKA
The goal of this RCT is to investigate efficacy between restricted kinematic alignment and mechanical alignment TKA in simultaneous bilateral TKA patients.
- Trial name
- NCT06323577
- Testing
- Restricted kinematic alignment, Mechanical alignment
- Where
- Thailand
- Volunteers
- 50 people
- Sponsor
- Thammasat University Hospital
Bariatric Surgery, Surgery
Optimizing Function Outcomes After Bariatric Surgery With Core Stabilization Training: A Randomized Controlled Study
Bariatric surgery has been reported to be the most effective treatment option for losing and maintaining body weight and improving comorbidities and mortality associated with morbid obesity.
- Trial name
- NCT04932694
- Testing
- Core stabilization training
- Where
- 2 sites in Egypt, Saudi Arabia
- Volunteers
- 54 people
- Sponsor
- Cairo University
Muscle Mass and Strength, Obesity & Overweight
Function and Lean Mass Preservation With Resistance Exercise During a GLP-1RA Treatment
This study aims to investigate the effect that a structured, progressive resistance exercise program may have on maintaining the muscle mass and physical function of overweight/ obese females whilst they experience a tirzepatide…
- Conditions
- Muscle Mass and Strength, Obesity & Overweight, Physical Function
- Trial name
- FLEX (NCT07457437)
- Testing
- Progressive Resistance Exercise Training Program, Habitual physical activity guidelines
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Cerebral Palsy, Spastic, Cerebral Palsy, Dyskinetic
Functional Benefits of Multisite Surgery for the Upper Limb of Children With Cerebral Palsy
The aim of the study is to investigate the impact of individualized multisite neuro-orthopedic surgery of the upper limb in children with Cerebral Palsy on unilateral functional capacities and bimanual performance.
- Conditions
- Cerebral Palsy, Spastic, Cerebral Palsy, Dyskinetic, Infantile Hemiplegic Cerebral Palsy
- Trial name
- NCT04395729
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française
Spastic Diplegic Cerebral Palsy
Efficacy and Functional Outcomes of Botulinum Toxin A Injections to Hamstrings in Flexed Knee Gait in Cerebral Palsy
The study proposes to determine if injections of BTX-A to the hamstring muscles result in measurable physiologic changes not observed with normal saline injections in children with spastic diplegic cerebral palsy who walk with a…
- Trial name
- NCT00261131
- Testing
- Botulinum Toxin A
- Volunteers
- 250 people
- Sponsor
- Shriners Hospitals for Children
Rectal Cancer
Longterm Functional Outcomes in Patients Undergoing Organ Preserving Treatment for Rectal Cancer With or Without Local Excision After Chemoradiotherapy
Treatment of rectal cancer by standard neoadjuvant chemoradiotherapy protocols leads to a complete response in about 15% of patients, or even a higher fraction if radiotherapy is followed by an Oxaliplatin based chemotherapy as…
- Trial name
- PRESERVE (NCT06249672)
- Testing
- Local excision
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Macromastia, Hypertrophy Breast
Satisfaction, Pain and Function Outcomes of Breast Reduction Patients
To explore the indications and benefits of breast reduction. The investigators suspect all of the patients in this population suffer from neck/back pain and limitations in function.
- Trial name
- NCT05288530
- Volunteers
- 35 people
- Sponsor
- Claytor Noone Plastic Surgery
Childhood Traumatic Grief, Post Traumatic Stress
Randomized Controlled Trial of Trauma-focused CBT in Tanzania and Kenya
The primary goal is to study the effectiveness of Trauma-focused Cognitive Behavioral Therapy (TF-CBT) in treating traumatic grief and traumatic stress for orphaned children and young adolescents in two East African sites with…
- Conditions
- Childhood Traumatic Grief, Post Traumatic Stress, Post Traumatic Stress Disorder, Depressive Symptoms
- Trial name
- NCT01822366
- Testing
- Trauma-focused Cognitive Behavioral Therapy
- Where
- 3 sites in United States, Kenya and 1 more
- Volunteers
- 1,280 people
- Sponsor
- Duke University
Ankle Sprains, Chronic Ankle Instability
Cognitive Behavioral Based Physical Therapy for Patients With Chronic Ankle Instability
The purpose of this study is to investigate the feasibility of a psychologically informed physical therapy intervention in individuals with Chronic Ankle Instability.
- Trial name
- NCT07237581
- Testing
- CBPT/HEP, HEP Only
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Creighton University
Clinical Outcomes
MAKO-Uni-Knee Arthroplasty Clinical Outcomes and Function
This study represents a single-surgeon/institution, non-randomized, consecutive series, prospective and comparative cohort design.
- Trial name
- NCT03354195
- Testing
- Unicompartmental knee arthroplasty with the Mako Robotic Arm-assisted system.
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Foundation for Orthopaedic Research and Education
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.