Clinical trials: Functional Outcomes
Outcome, Fatal, Infection
A Pharmacokinetics Study of Daptomycin in Critically Ill Patients and Effects of Daptomycin on Kidney
Daptomycin ，is the first approved member of a new class of antimicrobials, the cyclic lipopeptides, and presents selective action against gram-positive bacteria, including methicillin- and vancomycin-resistant strains，disrupting…
- Trial name
- NCT04277143
- Testing
- Daptomycin
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Zhongnan Hospital
Stroke
StroCare - Optimised Cross-sectoral,Coordinated Treatment of Stroke Patients With Patient-orientated Outcome Measurement
The Trial is a multi-centred controlled interventional study with a pre-post design. The primary aim of the study is the evaluation of the effectiveness and cost-effectiveness of the StroCare treatment.
- Trial name
- StroCare (NCT04159324)
- Testing
- optimized cross-sectoral, structured and coordinated treatment pathway that integrates a patient-centred outcome evaluation
- Where
- Germany
- Volunteers
- 409 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Benign Prostatic Hyperplasia
Preoperative Anxiety and Surgical Fear in Holmium Laser Enucleation of the Prostate and Transurethral Resection of the Prostate Patients With Benign Prostatic Hyperplasia
Benign prostatic hyperplasia (BPH) is a common condition in older men and may cause bothersome lower urinary tract symptoms that can negatively affect quality of life.
- Trial name
- HoLEP and TURP (NCT07663097)
- Testing
- Holmium Laser Enucleation of the Prostate (HoLEP), Transurethral Resection of the Prostate (TURP)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Hitit University
Neoplasms Prostate, Cancer of the Prostate
MRI/Ultrasound Fusion Guided Prostate Cryotherapy
Registration of Prostate Cancer patients undergoing Prostate Cryotherapy guided by Mutiparametric-MRI (MP-MRI) highlighting biopsy confirmed regions. The primary outcome measure is 5 year oncological control.
- Trial name
- FIPC (NCT02381990)
- Testing
- FUSE IMAGE MRI GUIDED PROSTATE CRYOTHERAPY
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Urological Research Network, LLC
Appendectomy, Laparoscopic
Functional Outcomes of Open vs Laparoscopic Appendectomy
this study compare between open and laparoscopic appendectomy
- Trial name
- NCT07696143
- Testing
- open appendectomy, lap appendectomy
- Where
- Egypt
- Volunteers
- 832 people
- Sponsor
- Zagazig University
Knee Arthritis, Osteoarthritis, Osteo Arthritis of the Knee
Quadriceps Muscle Quality and Clinical Outcomes in Knee Osteoarthritis
The purpose of this cross-sectional, observational study is to evaluate the relationship between quadriceps muscle quality-specifically muscle echogenicity and thickness change during isometric contraction-and clinical outcomes…
- Trial name
- NCT07541274
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Izmir City Hospital
Diastasis Recti and Weakness of the Linea Alba, Abdominal Wall Defect
Patient-Reported Outcomes in Women With Postpartum Abdominal Wall Insufficiency (PPAWIS)
Postpartum abdominal wall insufficiency syndrome (PPAWIS) is a multidimensional condition that may affect physical function, quality of life, body image, and sexual health in women after childbirth.
- Conditions
- Diastasis Recti and Weakness of the Linea Alba, Abdominal Wall Defect, Postpartum Complication, Abdominal Wall Anomaly
- Trial name
- EMPOWER (NCT07407374)
- Testing
- Routine Clinical Care
- Volunteers
- 30 people
- Sponsor
- Swissmed Hospital
Major Depressive Disorder
Treatment Outcome in Major Depressive Disorder
Major Depressive Disorder (MDD) is one of the most severe and frequently occurring brain disorders worldwide. It has been linked to serotonergic dysfunction, sexual dysfunction, vulnerability to stress and neuro-inflammation.
- Trial name
- NCT02869035
- Testing
- Escitalopram, Duloxetine
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cervical Spinal Stenosis, Cervical Myelopathy
CSS-Assessing the Course of Degenerative Cervical Spinal Stenosis Using Functional Outcomes
The study will consist of two parts: In Study A, objectively assessed physical activity, gait, balance, range of movement of specific joints during walking and neurophysiological findings between patients with cervical spine…
- Trial name
- NCT04381663
- Testing
- conservative treatment, surgical treatment
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University Hospital, Basel, Switzerland
Social Work, Psychiatric, Physiotherapy
Social Work-Supported Physiotherapy and Psychosocial Outcomes in Third Age University and Nursing Home Residents
The aging process is considered not only as a phase characterized by changes in physical functioning, but also as a multidimensional life stage affecting psychosocial well-being, social participation, and quality of life.
- Trial name
- NCT07525596
- Testing
- Social Work-Supported Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Munzur University
Feeding Disorders, Anorexia Nervosa
Technological Balance Rehabilitation in Feed and Eating Disorders
Postural control depends on the central integration of vestibular, visual, and somatosensory inputs and the integrity of the neural efferent motor pathway, which continuously provides postural adjustments to environmental and…
- Conditions
- Feeding Disorders, Anorexia Nervosa, Bulimia Nervosa
- Trial name
- ROAR-FED (NCT06641973)
- Testing
- Robotic balance rehabilitation with hunova® robotic platform
- Where
- Italy
- Volunteers
- 72 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Diabetic Foot Ulcer
At-Home Exercise Study for Veterans With Healed Diabetic Foot Ulcers
Foot ulcers and amputations are a common and feared complication for people with diabetes. People with a diabetic foot ulcer have a higher risk of dying within five years than people with diabetes without an ulcer.
- Trial name
- NCT06312579
- Testing
- 12-week home based exercise, 12-week standard of care
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- VA Office of Research and Development
Satisfaction, Patient
The Outcomes of Subject After Total Knee Arthroplasty
Total Knee Arthroplasty (TKA) is a standard of intervention for severe knee osteoarthritis, also been proven with benefits in improving pain, mobility, and quality of life. However, the outcomes after TKA is controversial.
- Trial name
- NCT05810090
- Testing
- Total knee arthroplasty
- Where
- Taiwan
- Volunteers
- 631 people
- Sponsor
- Changhua Christian Hospital
Covid19, Corona Virus Infection
Functional Recovery of Hospitalised Patients With COVID-19: The COREG Extension Study
Older adults and those with chronic underlying health conditions are the most susceptible to COVID-19 and its complications. Although there has been a rapid response to studying the effects of COVID-19 in the acute stages, little…
- Conditions
- Covid19, Corona Virus Infection, Mobility Limitation, Frailty
- Trial name
- NCT04602260
- Where
- Canada
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- McMaster University
Kidney Disease, Liver Disease
Remote Ischemic Preconditioning In Abdominal Organ Transplantation
Does remote ischemic preconditioning (RIPC) induced by a brief period of occlusion of blood flow to the lower extremity prior to organ recovery in deceased donors, improve short and long term outcomes after transplantation of…
- Conditions
- Kidney Disease, Liver Disease, Pancreas Disease
- Trial name
- RIPCOT (NCT00975702)
- Testing
- RIPC by Inflation of Pneumatic Tourniquet
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Neck Pain
Body Composition and Cervical Outcomes in Non-Specific Neck Pain
Non-specific neck pain (NSNP) is a common musculoskeletal condition that significantly affects quality of life, daily activities, and work productivity.
- Trial name
- NCT07388706
- Testing
- Clinical Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Postoperative Cognitive Dysfunction, Geriatrics
GDFT and Postoperative Cognitive Function in Geriatric Cancer Surgery
Postoperative cognitive decline remains a common and clinically significant complication among geriatric patients undergoing major abdominal cancer surgery.
- Conditions
- Postoperative Cognitive Dysfunction, Geriatrics, Abdominal Neoplasm, Hemodynamics
- Trial name
- NCT07438249
- Testing
- Masimo Root Hemodynamic Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Lung Cancer, Surgery
Effects of Inspiratory Muscle Training After Lung Cancer Surgery, a Randomized Controlled Trial
The purpose of this study is to evaluate the effects of postoperative inspiratory muscle training on the recovery of respiratory muscle strength in high risk patients referred for lung cancer surgery.
- Trial name
- NCT01793155
- Testing
- Inspiratory muscle training
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Aalborg University Hospital
Total Knee Replacement
Robotic Assisted TKA
As an intraoperative tool, a modern robotic total knee arthroplasty (TKA) system should be able to identify a patient's native femoral and tibial anatomy, as well as, assess ligament tension and gap balance.
- Trial name
- NCT06062615
- Testing
- Total knee replacement using Omnibot Knee System, Conventional Total knee replacement, Omnibot Robotic Knee System
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Triple Negative Breast Cancer (TNBC)
Evaluating Ovarian Toxicity Outcomes Following Immunotherapy in Patients With Triple-Negative Breast Cancer (TNBC)
This study aims to collect information about the effects of chemotherapy combined with immunotherapy (immune checkpoint inhibitors) for early-stage triple-negative breast cancer (TNBC) on ovarian function and fertility.
- Trial name
- FERTILE (NCT07527819)
- Where
- 9 sites in Australia
- Volunteers
- 75 people
- Sponsor
- Peter MacCallum Cancer Centre, Australia
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