Clinical trials: Functional Outcomes
Stroke, Paralysis Arm
Exergame and Robotic Therapy Impact on Tenascin-C and Functional Outcome on Stroke Patients
This clinical trial aims to compare the effectiveness of Robotic versus Exergame versus Standard therapy to improve hand function among post-stroke patients.
- Trial name
- NCT06563206
- Testing
- Exergame, Robotic, Conventional
- Where
- 2 sites in Indonesia
- Volunteers
- 48 people
- Sponsor
- Hasanuddin University
Charcot Marie Tooth Disease (CMT), Pes Cavovarus
Walking Function Outcomes Following Surgical Correction With Rehabilitation Versus Physical Therapy Alone in Charcot-Marie-Tooth Disease: A Bidirectional Cohort Study
The goal of this study is to compare changes in walking ability in people with Charcot-Marie-Tooth disease (CMT) who receive two different treatment approaches for foot deformities that affect walking.
- Conditions
- Charcot Marie Tooth Disease (CMT), Pes Cavovarus, Surgery, Exercise Training
- Trial name
- CMT-WALK (NCT07432035)
- Testing
- Functional Surgery plus Rehabilitation, Physical Exercise
- Volunteers
- 200 people
- Sponsor
- Peking University Third Hospital
Flexor Tendon Injury, Tendon Injury - Hand
Effects of Different Wrist Positions in Dorsal Blocking Orthoses After Flexor Tendon Repair
This randomized controlled study aims to compare the effects of three different wrist positions (30° extension, neutral, and 30° flexion) used in dorsal blocking orthoses during early active mobilization after zone I-II flexor…
- Trial name
- NCT07489235
- Testing
- 3D-Printed Dorsal Blocking Orthosis (wrist 30 degree extension), 3D-Printed Dorsal Blocking Orthosis (wrist neutral), 3D-Printed Dorsal Blocking Orthosis (wrist 30 degree flexion)
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Sedanur Güngör
Kinematical Alignment,Mechanical Alignment, Navigation
A Randomised Control Trial Comparing Functional Outcomes for Navigated Kinematically Aligned TKR Versus Navigated Mechanically Aligned TKR
The overall aim of the study is to compare navigated kinematically aligned total knee replacements (KA TKR) with navigated mechanically aligned TKR (MA TKR) in terms of function and ROM The objectives are therefore: 1.
- Trial name
- MaKKRO (NCT04246138)
- Testing
- alignment types
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Pelvic Organ Prolapse
Anatomical and Functional Outcomes of Perigee and Apogee Mesh in Total Pelvic Floor Reconstruction Versus Gynecare Prolift
The investigators designed a prospective study in this article to evaluate the efficacy, the life quality and the complications of two different meshes of type I (one is Perigee/Apogee, the other is named Gynecare prolift) versus…
- Trial name
- mesh (NCT03070873)
- Testing
- Perigee and Apogee Mesh, Gynecare Prolift Mesh, Traditional Surgery
- Volunteers
- 258 people
- Sponsor
- Nanjing Medical University
Congestive Heart Failure
The Registry Evaluating Functional Outcomes of Resynchronization Management
The purpose of this study is to evaluate the functional outcomes of resynchronization management and to describe the patient psychosocial characteristics (depression ad anxiety) and associated outcomes with electrophysiologic…
- Trial name
- REFORM (NCT00959179)
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Saint Luke's Health System
Functional Ankle Instability, Kinesiophobia
Comparative Effect of Combined Strength, Core and Balance Training on Kinesiophobia, Ankle Instability, Functional Outcomes, and Performance in Table Tennis Players With Functional Ankle Instability
This randomized controlled trial investigates the comparative effect of combined strength and balance training versus balance and core training on kinesiophobia (fear of movement), ankle instability, functional outcomes, and…
- Conditions
- Functional Ankle Instability, Kinesiophobia, Sports Rehabilitation, Neuromuscular Control
- Trial name
- NCT07671170
- Testing
- Experimental : Combined Strength and Balance Training, Control : Balance and Core Training
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Ibadat International University, Islamabad
Hemianopsia, Homonymous, Brain Injury
Biofeedback for Hemianopia Vision Rehabilitation
Patients with brain injury secondary to stroke, surgery, or trauma frequently suffer from homonymous hemianopia, defined as vision loss in one hemifield secondary to retro- chiasmal lesion.
- Conditions
- Hemianopsia, Homonymous, Brain Injury, Stroke, Brain Tumor
- Trial name
- NCT05397873
- Testing
- Biofeedback training
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- University Health Network, Toronto
Patient Reported Outcome Measures, Recovery of Function
FIT Study (Functional Outcomes In Trauma Study)
Why? There is not much information in the UK on how well patients who sustain major trauma function afterwards. Major trauma is defined as significant injuries with a calculated 'injury severity score' (ISS) over 15.
- Conditions
- Patient Reported Outcome Measures, Recovery of Function, Rehabilitation, Disability Evaluation
- Trial name
- NCT04074382
- Testing
- Online Questionnaires, Qualitative Interviews
- Where
- United Kingdom
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Knee Osteoarthritis
Gastrocnemius Myofascial Release in Females With Knee Osteoarthritis
The goal of this clinical trial is to determine whether gastrocnemius myofascial release is effective in reducing pain and improving physical function in females with knee osteoarthritis.
- Trial name
- MFR/KNEE OA (NCT07507175)
- Testing
- GASTROCNEMIUS MYOFASCIAL RELEASE
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Vestibular Disorder, Headache
The Effect of OMT on Functional Outcomes and Anti-inflammatory Biomarkers in Mild to Moderate Traumatic Brain Injury
Test the hypothesis that a certain set of osteopathic manipulation procedures preformed on patients with mild to moderate traumatic brain injury will result in accelerated rates of recovery assessed using vestibular function…
- Conditions
- Vestibular Disorder, Headache, Traumatic Brain Injury
- Trial name
- NCT03163901
- Testing
- Osteopathic Manipulative Treatment
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Surgery
Brain Function Monitoring During Surgery
The purpose of this research is to gather information on the effectiveness of the Sedline Brain Function Monitor, and its use in this study to determine whether monitoring the brain activity during anesthesia will improve…
- Trial name
- NCT06619730
- Testing
- Sedline Brain Function Monitor
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Chicago
Knee Osteoarthritis
Corticosteroid vs Platelet-Rich Plasma Intra-articular Injections in the Treatment of Knee Osteoarthritis.
This study will explore the effectiveness of intra-articular knee injections in patients with osteoarthritis by comparing Corticosteroid (triamcinolone) vs Platelet Rich Plasma (PRP).
- Trial name
- NCT06032039
- Testing
- Triamcinolone, Platelet Rich Plasma
- Where
- Jamaica
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- The University of The West Indies
Nutrition, Healthy
Functional and Nutritional Plant-based Mixed Protein Study (FuN Protein Study)
The study aims to investigate the effects of optimized plant protein mixtures versus their animal protein equivalents on satiety, protein metabolism, and overall metabolic health
- Trial name
- NCT06421194
- Testing
- Investigational meal 1 - Commercial animal-based protein foods [Siew mai (6 pieces) and Ngoh hiang (2 pieces)], Investigational meal 2- Commercial animal-based protein foods [Gyoza (11 pieces) and Luncheon meat (5 pieces)], Investigational meal 3- Formulated plant-based protein foods [Siew mai (6 pieces) and Ngoh hiang (1 piece cut into 2)]
- Where
- Singapore
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Food and Biotechnology Innovation
Neurologic Disorder, Neurologic Diseases
Functional Outcomes and Control Using Synchron BCI - Australia
Functional Outcomes and Control Using Synchron BCI - Australia (FOCUS-AUS)
- Conditions
- Neurologic Disorder, Neurologic Diseases, MND (Motor Neurone DIsease), Motor Neuron Disease
- Trial name
- FOCUS-AUS (NCT07533903)
- Testing
- Stentrode
- Where
- Australia
- Volunteers
- 10 people
- Sponsor
- Synchron, Inc.
Skull Base Pathology
Olfactory Function Following Endoscopic Endonasal Skull Base Surgery
The purpose of this study is to compare a subject's sense of smell before and after endoscopic endonasal surgery to remove a skull base abnormality (i.e.
- Trial name
- UPSIT (NCT02165969)
- Testing
- endoscopic endonasal surgery with UPSIT
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Ricardo L. Carrau, MD
Stroke, Cerebral Infarction
Platelet Hyperreactivity to Aspirin and Stroke
STUDY QUESTIONS What is the real prevalence of platelet "resistance" to aspirin during the acute phase of stroke and after 3 months, and 1 year, as measured using different platelet function tests? Do all methods measure similar…
- Conditions
- Stroke, Cerebral Infarction, Cardiovascular Diseases, Vascular Diseases
- Trial name
- PLARAS (NCT00766896)
- Testing
- Aspirin (platelet sensitive versus platelet hyperreactivity)
- Where
- Brazil
- Volunteers
- 203 people
- Sponsor
- University of Sao Paulo
Neovascular Age-related Macular Degeneration
Functional and Structural Outcomes in Neovascular Age-related Macular Degeneration
Several studies during the last years reported the involvement of anti-retinal autoantibodies in ocular disorders, such as AMD. These studies support the growing evidence of an immunological involvement in the pathogenesis of…
- Trial name
- CAPTAIN (NCT02843490)
- Testing
- Ranibizumab
- Where
- Germany
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
Heart Failure, Congestive
Placebo-Controlled Randomized Study of KW-3902 for Subjects Hospitalized With Worsening Renal Function and Heart Failure Requiring IV Therapy
To evaluate the effect of KW-3902IV, in addition to standard therapy, on the proportion of worsening heart failure and worsening renal function, and on the proportion of deaths or rehospitalizations for heart failure or worsening…
- Trial name
- REACH UP (NCT00443690)
- Testing
- rolofylline
- Volunteers
- 480 people
- Sponsor
- NovaCardia, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Age-Related Balance Impairment, Healthy Older Adults
Effects of Dynamic Neuromuscular Stabilization Exercises Versus Balance Exercises in Older Adults
The aim of this study is to compare the effects of Dynamic Neuromuscular Stabilization (DNS) based exercises and balance exercises on functional capacity, balance, muscle strength, and quality of life in older adults.
- Trial name
- NCT07495280
- Testing
- Dynamic Neuromuscular Stabilization Exercises, Balance Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
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